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Browse our CACNA1A (CACNA1A) ELISA Kits

Full name:
Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit ELISA Kits (CACNA1A)
On www.antibodies-online.com are 10 Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A) ELISA Kits from 4 different suppliers available. Additionally we are shipping CACNA1A Antibodies (32) and CACNA1A Proteins (6) and many more products for this protein. A total of 48 CACNA1A products are currently listed.
Synonyms:
alpha1A, APCA, BccA1, BI, ca(v)2.1, Caca1a, CACH4, CACN3, cacna-a, cacna1a, Cacnl1a4, CAV2.1, Ccha1a, EA2, FHM, HPCA, la, leaner, MHP, MHP1, nmf352, rbA-1, rkr, rocker, SCA6, si:ch211-237k17.1, tg, tottering
list all ELISA KIts Gene Name GeneID UniProt
CACNA1A 25398 P54282
CACNA1A 773 O00555
CACNA1A 12286 P97445

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More ELISA Kits for CACNA1A Interaction Partners

Zebrafish Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A) interaction partners

  1. The efficient activation of CaV2.1 channels during action potentials may contribute to the highly reliable transmission at zebrafish neuromuscular junctions.

Human Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A) interaction partners

  1. To assess the gene dosage effect in SCA6 homozygotes, study determined the effect of CACNA1A CAG repeat (show CELF3 ELISA Kits) length on the age-of-onset in heterozygotes, found that the total number of CAG repeats in both the normal and expanded alleles was inversely correlated with the age-of-onset in SCA6

  2. Electrophysiological characterization of VDCC currents revealed that the suppressive effect of RIM2alpha on voltage-dependent inactivation (VDI) was stronger than that of RIM1alpha (show RIMS1 ELISA Kits) for the CaV2.1 variant containing the region encoded by exons 44 and 47.

  3. Mutations in SLC1A2 (show SLC1A2 ELISA Kits) and CACNA1A Are Important Causes of Epileptic Encephalopathies

  4. Eye movement disorders are an early manifestation of CACNA1A mutations phenotype in children.

  5. The presence of SCN1A (show SCN1A ELISA Kits) mutations and absence of mutations in ATP1A2 (show ATP1A2 ELISA Kits) or CACNA1A suggest that the Polish patients represent FHM type 3.

  6. South American cohort did not confirm the effect of the four candidate loci as modifier of onset age: mithocondrial A10398G polymorphism and CAGn at RAI1 (show DOM3Z ELISA Kits), CACNA1A, ATXN3 (show ATXN3 ELISA Kits), and ATXN7 (show ATXN7 ELISA Kits) genes

  7. Cav2.1 dysfunction in episodic ataxia (show USP14 ELISA Kits) type 2 has unexpected effects on axon excitability.

  8. CACNA1A might play a role in the etiology of autism as demonstrated in the Chinese Han population

  9. Expression of DnaJ-1 (show DNAJC14 ELISA Kits) potently suppresses alpha1ACT-dependent degeneration , concomitant with decreased aggregation of the pathogenic protein. Mutating the nuclear importer karyopherin a3 (show KPNA4 ELISA Kits) also leads to reduced toxicity from pathogenic CACNA1A

  10. This report illustrates the phenotypic heterogeneity of CACNA1A loss-of-function mutations and stresses the cognitive and epileptic manifestations caused by the loss of CaV2.1 channels function

Mouse (Murine) Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A) interaction partners

  1. Electrophysiological characterization of VDCC currents revealed that the suppressive effect of RIM2alpha on voltage-dependent inactivation (VDI) was stronger than that of RIM1alpha (show RIMS1 ELISA Kits) for the CaV2.1 variant containing the region encoded by exons 44 and 47.

  2. Cacna1a mutation plays a significant role in protein expression patterns in cerebellum of mutant mice.

  3. Our findings that BAG3 (show BAG3 ELISA Kits) is localized at the sarcolemma and t-tubules while modulating myocyte contraction and action potential duration through specific interaction with the beta1-adrenergic receptor and L-type Ca(2 (show CA2 ELISA Kits)+) channel provide novel insight into the role of BAG3 (show BAG3 ELISA Kits) in cardiomyopathies and increased arrhythmia risks in heart failure.

  4. Findings demonstrate that the mutant Cav2.1 channel exerts a protective effect against cryogenic brain injury in rolling Nagoya mice

  5. results indicate that regulation of CaV2.1 channels by Ca(2 (show CA2 ELISA Kits)+) sensor proteins is essential for normal synaptic plasticity at the neuromuscular junction and for muscle strength, endurance, and motor coordination in mice in vivo

  6. regulation of CaV2.1 channels by calcium sensor proteins is required for normal short-term plasticity

  7. Thus, GHSR1a differentially inhibits CaV2 (show CAV2 ELISA Kits) channels by Gi/o or Gq protein pathways depending on its mode of activation.

  8. Genetic ablation of Cacna1a in layer VI neurons produced Absence Epilepsy.

  9. CACNA1A regulates lysosomal fusion with endosomes and autophagosomes and is required for neuronal homeostasis.

  10. CaV2.1 Ca2 (show CA2 ELISA Kits)+ channel mutation leads to developmental abnormalities in Cl- transporter expression and GABAA (show GABRg1 ELISA Kits) receptor compositions in hippocampal neurons.

Cow (Bovine) Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A) interaction partners

  1. new information on the hypothalamic expression of alpha1A and alpha1D subunits during development in a mammal with a long gestation period and a large and convoluted brain.

  2. cloned the full-length alpha1A subunit

Rabbit Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A) interaction partners

  1. Gem (show GEM ELISA Kits) contains two candidate inhibitory sites, each capable of producing full inhibition of P/Q-type Ca(2 (show CA2 ELISA Kits)+) channels.

  2. describe a CACNA1A mutation (A454T) that disturbs the functional interaction between SNAREs and the poreforming alpha1A subunit, resulting in mutant P/Q channels that are less efficiently coupled to secretion.

CACNA1A Antigen Profile

Antigen Summary

Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas, the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1A subunit, which is predominantly expressed in neuronal tissue. Mutations in this gene are associated with 2 neurologic disorders, familial hemiplegic migraine and episodic ataxia 2. This gene also exhibits polymorphic variation due to (CAG)n-repeats. Multiple transcript variants encoding different isoforms have been found for this gene. In one set of transcript variants, the (CAG)n-repeats occur in the 3' UTR, and are not associated with any disease. But in another set of variants, an insertion extends the coding region to include the (CAG)n-repeats which encode a polyglutamine tract. Expansion of the (CAG)n-repeats from the normal 4-16 to 21-28 in the coding region is associated with spinocerebellar ataxia 6.

Alternative names and synonyms associated with CACNA1A

  • calcium channel, voltage-dependent, P/Q type, alpha 1A subunit (cacna1a) Elisa Kit
  • calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a (cacna1aa) Elisa Kit
  • calcium channel, voltage-dependent, P/Q type, alpha 1A subunit (CACNA1A) Elisa Kit
  • calcium channel, voltage-dependent, P/Q type, alpha 1A subunit (Cacna1a) Elisa Kit
  • P/Q-type voltage-gated calcium channel alpha1A subunit ChCaChA1A (LOC395892) Elisa Kit
  • alpha1A Elisa Kit
  • APCA Elisa Kit
  • BccA1 Elisa Kit
  • BI Elisa Kit
  • ca(v)2.1 Elisa Kit
  • Caca1a Elisa Kit
  • CACH4 Elisa Kit
  • CACN3 Elisa Kit
  • cacna-a Elisa Kit
  • cacna1a Elisa Kit
  • Cacnl1a4 Elisa Kit
  • CAV2.1 Elisa Kit
  • Ccha1a Elisa Kit
  • EA2 Elisa Kit
  • FHM Elisa Kit
  • HPCA Elisa Kit
  • la Elisa Kit
  • leaner Elisa Kit
  • MHP Elisa Kit
  • MHP1 Elisa Kit
  • nmf352 Elisa Kit
  • rbA-1 Elisa Kit
  • rkr Elisa Kit
  • rocker Elisa Kit
  • SCA6 Elisa Kit
  • si:ch211-237k17.1 Elisa Kit
  • tg Elisa Kit
  • tottering Elisa Kit

Protein level used designations for CACNA1A

calcium channel, voltage-dependent, P/Q type, alpha 1A subunit , voltage-dependent calcium ion channel alpha subunit , ZfCav2.1 , BI , RBA-I , brain calcium channel 1 , brain calcium channel I , brain class A , calcium channel alpha 1A , calcium channel, L type, alpha-1 polypeptide , calcium channel, voltage-dependent, alpha 1A subunit , voltage-dependent P/Q-type calcium channel subunit alpha-1A , voltage-gated calcium channel subunit alpha Cav2.1 , P/Q-type calcium channel alpha1A subunit , calcium channel, P/Q type, alpha 1A , calcium channel, alpha 1A subunit , voltage-gated calcium channel alpha 1A subunit , calcium channel BI-1 , calcium channel BI-2

GENE ID SPECIES
373828 Xenopus laevis
562059 Danio rerio
100021108 Monodelphis domestica
25398 Rattus norvegicus
773 Homo sapiens
12286 Mus musculus
282648 Bos taurus
100009265 Oryctolagus cuniculus
395892 Gallus gallus
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