CACNA1A Products
(Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A))
Categories
Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas, the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1A subunit, which is predominantly expressed in neuronal tissue. Mutations in this gene are associated with 2 neurologic disorders, familial hemiplegic migraine and episodic ataxia 2. This gene also exhibits polymorphic variation due to (CAG)n-repeats. Multiple transcript variants encoding different isoforms have been found for this gene. In one set of transcript variants, the (CAG)n-repeats occur in the 3' UTR, and are not associated with any disease. But in another set of variants, an insertion extends the coding region to include the (CAG)n-repeats which encode a polyglutamine tract. Expansion of the (CAG)n-repeats from the normal 4-16 to 21-28 in the coding region is associated with spinocerebellar ataxia 6. [provided by RefSeq, Mar 2010].
antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.
Featured CACNA1A Categories
CACNA1A Antibodies
High quality antibodies with extensive validation data.
CACNA1A ELISA Kits
Reliable ELISA kits for a wide range of species.
CACNA1A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CACNA1A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7175608
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN306878
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN6243080
Quantity
200 μL
Datasheet
Datasheet
Recommended CACNA1A ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965321
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965320
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1167089
Quantity
96 tests
Datasheet
Datasheet
Recommended CACNA1A Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3090203
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3121194
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3090205
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our CACNA1A products
: "The Cav2.1/alpha1A (P/Q-type) voltage-dependent calcium channel mediates inhibitory neurotransmission onto mouse cerebellar Purkinje cells." in: The European journal of neuroscience, Vol. 13, Issue 10, pp. 1902-12, (2001) (PubMed).: "Vascular smooth muscle cells express the alpha(1A) subunit of a P-/Q-type voltage-dependent Ca(2+)Channel, and It is functionally important in renal afferent arterioles." in: Circulation research, Vol. 87, Issue 10, pp. 896-902, (2000) (PubMed).
Synonyms and alternative names related to CACNA1A
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit S homeolog (cacna1a.S), calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a (cacna1aa), calcium voltage-gated channel subunit alpha1 A (CACNA1A), calcium voltage-gated channel subunit alpha1 A (Cacna1a), calcium channel, voltage-dependent, P/Q type, alpha 1A subunit (Cacna1a), P/Q-type voltage-gated calcium channel alpha1A subunit ChCaChA1A (LOC395892), alpha1A, APCA, BccA1, BI, ca(v)2.1, Caca1a, CACH4, CACN3, cacna-a, cacna1a, CACNL1A4, Cacnl1a4, cav2.1, Cav2.1, CAV2.1, Ccha1a, EA2, FHM, HPCA, la, leaner, MHP, MHP1, nmf352, rbA-1, rkr, rocker, SCA6, si:ch211-237k17.1, tg, totteringProtein level used designations for CACNA1A
- calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
- voltage-dependent calcium ion channel alpha subunit
- ZfCav2.1
- BI
- RBA-I
- brain calcium channel 1
- brain calcium channel I
- brain class A
- calcium channel alpha 1A
- calcium channel, L type, alpha-1 polypeptide
- calcium channel, voltage-dependent, alpha 1A subunit
- voltage-dependent P/Q-type calcium channel subunit alpha-1A
- voltage-gated calcium channel subunit alpha Cav2.1
- P/Q-type calcium channel alpha1A subunit
- calcium channel, P/Q type, alpha 1A
- calcium channel, alpha 1A subunit
- voltage-gated calcium channel alpha 1A subunit
- calcium channel BI-1
- calcium channel BI-2
You are here:
