Browse our Lysine (K)-Specific Demethylase 1A Proteins (KDM1A)

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Lysine (K)-Specific Demethylase 1A Proteins (KDM1A)
On www.antibodies-online.com are 9 Lysine (K)-Specific Demethylase 1A (KDM1A) Proteins from 6 different suppliers available. Additionally we are shipping Lysine (K)-Specific Demethylase 1A Antibodies (216) and Lysine (K)-Specific Demethylase 1A Kits (4) and many more products for this protein. A total of 245 Lysine (K)-Specific Demethylase 1A products are currently listed.
Synonyms:
1810043O07Rik, AA408884, Aof2, ARABIDOPSIS LYSINE-SPECIFIC HISTONE DEMETHYLASE, ATLSD1, ATSWP1, BHC110, D4Ertd478e, DKFZp459N2450, F23N19.21, F23N19_21, Kdm1, KDM1A, Lsd1, LSD1-like 1, LYSINE-SPECIFIC HISTONE DEMETHYLASE, mKIAA0601, RGD1562975, SWP1, wu:fb82e06, wu:fc51a02, wu:fj36a05, wu:fj66b06, xLSD1
list all proteins Gene Name GeneID UniProt
KDM1A 23028 O60341
KDM1A 99982 Q6ZQ88
Rat KDM1A KDM1A 500569  

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Lysine (K)-Specific Demethylase 1A Proteins (KDM1A) by Origin

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Top referenced Lysine (K)-Specific Demethylase 1A Proteins

  1. Human KDM1A Protein expressed in Baculovirus infected Insect Cells - ABIN2005873 : Kusaba, Ito, Morita, Iida, Sato, Fujimoto, Kawasaki, Tanaka, Hirochika, Nishimura, Tanaka: Rice NON-YELLOW COLORING1 is involved in light-harvesting complex II and grana degradation during leaf senescence. in The Plant cell 2007 (PubMed)

  2. Human KDM1A Protein expressed in HEK-293 Cells - ABIN2714763 : Boxer, Barajas, Tao, Zhang, Khavari: ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes. in Genes & development 2014 (PubMed)

More Proteins for Lysine (K)-Specific Demethylase 1A Interaction Partners

Human Lysine (K)-Specific Demethylase 1A (KDM1A) interaction partners

  1. This study identified histone modification by SUMO as the first post-translational modification that stimulates intranucleosomal demethylation by the developmentally critical LSD1-CoREST (show RCOR1 Proteins) complex.

  2. These findings provide insight into the regulation of LSD1 and Epithelial-to-Mesenchymal Transition (EMT (show ITK Proteins)) and identify MOF (show KAT8 Proteins) as a critical suppressor of EMT (show ITK Proteins) and tumor progression.

  3. High LSD1 expression is associated with colon cancer.

  4. results demonstrate that CoREST (show RCOR1 Proteins) and LSD1 downregulate the Notch (show NOTCH1 Proteins) pathway in the developing cerebral cortex

  5. LSD1 is a primary and positive regulator of the HPV16 E7-induced epithelial-mesenchymal transition in cervical cancer

  6. these results suggest that HDAC5 (show HDAC5 Proteins) is critical in regulating LSD1 protein stability through post-translational modification, and the HDAC5 (show HDAC5 Proteins)-LSD1 axis has an important role in promoting breast cancer development and progression.

  7. KDM1A inhibitors may be utilized to alleviate acquired resistance to sorafenib in hepatocellular carcinoma cells.

  8. This study identified the lysine-specific demethylase (show MBD2 Proteins) KDM1A as a novel interaction partner of ZEB2 and demonstrated that mouse and human T-cell acute lymphoblastic leukemia cells with increased ZEB2 levels critically depend on KDM1A activity for survival.

  9. LSD1 overexpression is associated with non-small cell lung cancer.

  10. a model in which the EZH2 (show EZH2 Proteins)/HOXA11 (show HOXA11 Proteins)-AS/LSD1 complex and HOXA11 (show HOXA11 Proteins)-AS/miR (show MLXIP Proteins)-1297/EZH2 (show EZH2 Proteins) cross-talk serve as critical effectors in gastric cancer tumorigenesis and progression.

Mouse (Murine) Lysine (K)-Specific Demethylase 1A (KDM1A) interaction partners

  1. through interaction with Zfp516, LSD1 is recruited to UCP1 (show UCP1 Proteins) and other brown adipose tissue-enriched genes.

  2. Study propose that KDM1A is a key regulator of spermatogenesis and germ cell maintenance in the mouse.

  3. This study demonstrates that the FGF19 (show FGF19 Proteins)-SHP (show LAMC1 Proteins)-LSD1 axis maintains homeostasis by suppressing unnecessary autophagic breakdown of cellular components, including lipids, under nutrient-rich postprandial conditions.

  4. This analysis identified that LSD1 is the only lysine demethylase (show MBD2 Proteins) required for myogenic differentiation and that KDM3B (show KDM3B Proteins), KDM6A (show KDM6A Proteins), and KDM8 (show JMJD5 Proteins) are the candidate lysine demethylases required for osteoblast differentiation.

  5. Class I KDACs facilitate Dex-induced transcriptional repression by suppressing LSD1 complex activity at selected target gene promoters

  6. The study describes an interaction network of STAT5a (show STAT5A Proteins)/LSD1/HDAC3 (show HDAC3 Proteins) and a dual function of LSD1/HDAC3 (show HDAC3 Proteins) on STAT5a (show STAT5A Proteins)-dependent transcription, defined by protein-protein interactions, genomic binding localization/affinity and motifs.

  7. that nuclear GSK3beta- and USP22 (show USP22 Proteins)-mediated KDM1A stabilization is essential for glioblastoma tumorigenesis

  8. MALDI-TOF (show FEZF2 Proteins) mass spectrometry indicates that hydrogen peroxide blocks labeling of cysteine 600, which we propose forms an intramolecular disulfide with cysteine 618 to negatively regulate the catalytic activity of KDM1A

  9. lysine-specific demethylase (show MBD2 Proteins) 1 LSD1 represses HSD11B1 (show HSD11B1 Proteins) (hydroxysteroid 11-beta-dehydrogenase isozyme 1), a key glucocorticoid-activating enzyme, independently from PRDM16 (show PRDM16 Proteins)

  10. RIP140 (show NRIP1 Proteins) protects LSD1's catalytic domain and antagonizes its Jade-2 (show PHF15 Proteins)-mediated ubiquitination and degradation.

Zebrafish Lysine (K)-Specific Demethylase 1A (KDM1A) interaction partners

  1. LSD1 plays a critical role in hair cell regeneration and might represent a novel biomarker and potential therapeutic approach for the treatment of hearing loss.

  2. results suggest that the LSD1-dependent shutdown of Etv2 (show ETV2 Proteins) gene expression may be a significant event required for hemangioblasts to initiate hematopoietic differentiation

  3. Results indicate that LSD1 demethylase (show MBD2 Proteins) activity is required for neuromast development in zebrafish larvae.

Pig (Porcine) Lysine (K)-Specific Demethylase 1A (KDM1A) interaction partners

  1. LSD1 gene has two transcripts and is expressed in various tissues and relatively higher in ovary, kidney, and spleen.

Arabidopsis thaliana Lysine (K)-Specific Demethylase 1A (KDM1A) interaction partners

  1. LSD1, EDS1, and PAD4 (show PADI4 Proteins) participate in the regulation of various molecular and physiological processes that influence Arabidopsis fitness.

  2. AtSWP1 and AtCZS represent two main components of a co-repressor complex that fine tunes flowering and is unique to plants.

  3. AtLSD1, similar to HsLSD1, has demethylase (show MBD2 Proteins) activity toward mono- and dimethylated Lys4 but not dimethylated Lys9 and Lys27 of histone 3. [LSD1]

Lysine (K)-Specific Demethylase 1A (KDM1A) Protein Profile

Protein Summary

This gene encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with Lysine (K)-Specific Demethylase 1A (KDM1A)

  • amine oxidase (flavin containing) domain 2 (AOF2)
  • lysine (K)-specific demethylase 1 (KDM1)
  • lysine (K)-specific demethylase 1A (KDM1A)
  • lysine (K)-specific demethylase 1A (kdm1a)
  • lysine (K)-specific demethylase 1A (Kdm1a)
  • lysine (K)-specific demethylase 1a (kdm1a)
  • Lysine-specific histone demethylase 1-1 (LDL1)
  • 1810043O07Rik protein
  • AA408884 protein
  • Aof2 protein
  • ARABIDOPSIS LYSINE-SPECIFIC HISTONE DEMETHYLASE protein
  • ATLSD1 protein
  • ATSWP1 protein
  • BHC110 protein
  • D4Ertd478e protein
  • DKFZp459N2450 protein
  • F23N19.21 protein
  • F23N19_21 protein
  • Kdm1 protein
  • KDM1A protein
  • Lsd1 protein
  • LSD1-like 1 protein
  • LYSINE-SPECIFIC HISTONE DEMETHYLASE protein
  • mKIAA0601 protein
  • RGD1562975 protein
  • SWP1 protein
  • wu:fb82e06 protein
  • wu:fc51a02 protein
  • wu:fj36a05 protein
  • wu:fj66b06 protein
  • xLSD1 protein

Protein level used designations for KDM1A

amine oxidase (flavin containing) domain 2 , lysine (K)-specific demethylase 1 , lysine (K)-specific demethylase 1A , BRAF35-HDAC complex protein BHC110 , FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit , flavin-containing amine oxidase domain-containing protein 2 , lysine-specific histone demethylase 1 , lysine-specific histone demethylase 1A , neuroprotective protein 3 , lsd1

GENE ID SPECIES
419571 Gallus gallus
456614 Pan troglodytes
718609 Macaca mulatta
100171870 Pongo abelii
100216250 Xenopus (Silurana) tropicalis
100557968 Anolis carolinensis
23028 Homo sapiens
99982 Mus musculus
478193 Canis lupus familiaris
500569 Rattus norvegicus
558450 Danio rerio
532997 Bos taurus
100127157 Sus scrofa
842582 Arabidopsis thaliana
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