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Browse our s100b Proteins (S100B)

Full name:
S100 Calcium Binding Protein B Proteins (S100B)
On are 58 S100 Calcium Binding Protein B (S100B) Proteins from 19 different suppliers available. Additionally we are shipping s100b Antibodies (445) and s100b Kits (69) and many more products for this protein. A total of 584 s100b products are currently listed.
AI266795, AI850290, Bpb, NEF, S100, S100-B, S100a, S100beta, S100P
list all proteins Gene Name GeneID UniProt
S100B 20193 P56565
S100B 6285 P04271
S100B 25742 P04631

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s100b Proteins (S100B) by Origin

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Top referenced s100b Proteins

  1. Human s100b Protein expressed in Human Cells - ABIN2002268 : Allore, OHanlon, Price, Neilson, Willard, Cox, Marks, Dunn: Gene encoding the beta subunit of S100 protein is on chromosome 21: implications for Down syndrome. in Science (New York, N.Y.) 1988 (PubMed)
    Show all 5 references for ABIN2002268

  2. Mouse (Murine) s100b Protein expressed in Human Cells - ABIN2008480 : Esposito, Scuderi, Lu, Savani, De Filippis, Iuvone, Steardo, Sheen, Steardo: S100B induces tau protein hyperphosphorylation via Dickopff-1 up-regulation and disrupts the Wnt pathway in human neural stem cells. in Journal of cellular and molecular medicine 2008 (PubMed)
    Show all 5 references for ABIN2008480

  3. Human s100b Protein expressed in Escherichia coli (E. coli) - ABIN2181721 : Smith, Shaw: A novel calcium-sensitive switch revealed by the structure of human S100B in the calcium-bound form. in Structure (London, England : 1993) 1998 (PubMed)
    Show all 3 references for ABIN2181721

  4. Human s100b Protein expressed in Escherichia coli (E. coli) - ABIN667150 : Ayilavarapu, Kantarci, Fredman, Turkoglu, Omori, Liu, Iwata, Yagi, Hasturk, Van Dyke: Diabetes-induced oxidative stress is mediated by Ca2+-independent phospholipase A2 in neutrophils. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 2 references for ABIN667150

  5. Mouse (Murine) s100b Protein expressed in Escherichia coli (E. coli) - ABIN667030 : Shin, Bing, Chae, Kim, Bach, Park, Yamada, Nabeshima, Kim: Role of microsomal epoxide hydrolase in methamphetamine-induced drug dependence in mice. in Journal of neuroscience research 2009 (PubMed)
    Show all 2 references for ABIN667030

More Proteins for s100b Interaction Partners

Mouse (Murine) S100 Calcium Binding Protein B (S100B) interaction partners

  1. S100B inhibits C3H/10T1/2 murine embryonic mesenchyma.l cells into osteoblasts. S100B stimulates C3H/10T1/2 cell differentiation into adipocytes.

  2. The results of this study showed that S100B affects behavioral despair in female mice through functional interaction with the 5-HT7 (show HTR7 Proteins) receptor.

  3. Data show that S100B has direct effects on macrophages, enhancing particularly CCL22 (show CCL22 Proteins) and IL-1beta (show IL1B Proteins) expression and modulates the inflammatory response in uveoretinitis and this is likely to be, at least in part, via a direct effect on macrophages.

  4. Data show that high glucose increased protein-protein interaction between Steap4 (show STEAP4 Proteins) and S100B in mesangial (MES13) cells.

  5. S100A1 (show S100A1 Proteins)-KO exhibited increased right ventricular (RV) weight and elevated RV pressure in the absence of altered left ventricular filling pressures, increase in wall thickness of muscularized pulmonary arteries and a reduction in microvascular perfusion.

  6. high glucoseinduced profibrotic genes (TGFbeta (show TGFB1 Proteins), type IV collagen (show COL4 Proteins) and fibronectin (show FN1 Proteins)) and cell hypertrophyrelated p21WAF1 are dependent on S100B.

  7. S100A1 (show S100A1 Proteins) and S100B are dispensable for endochondral ossification during skeletal development.

  8. S100A1 ablationalso reduced plaque associated and increased non-plaque associated PO4-Akt and PO4-GSK3beta staining.

  9. Patients with acute myocardial infarction (MI) showed significantly increased S100A1 (show S100A1 Proteins) serum levels. Experimental MI in mice induced comparable S100A1 (show S100A1 Proteins) release. S100A1 (show S100A1 Proteins) signaling in cardiac fibroblasts occurs through endosomal TLR4 (show TLR4 Proteins)/MyD88 (show MYD88 Proteins).

  10. Data suggest up-regulation of S100b/RAGE (show AGER Proteins) (advanced glycosylation end-product receptor) signaling plays role in inflammatory interaction between adipocytes/macrophages; adipocyte secretion of S100b is up-regulated by Tnf (tumor necrosis factor-alpha (show TNF Proteins)).

Human S100 Calcium Binding Protein B (S100B) interaction partners

  1. this study shows that low levels of S100B correlate to a better anti-CTLA-4 (show CTLA4 Proteins) immunotherapy response and survival in advanced melanoma patients

  2. Our data suggest that elevated S100B protein levels might indicate neuronal damage in the brains of people with cannabis use disorder.

  3. The strong CD68 (show CD68 Proteins) and S100 co-expression in our case did not allow a clear-cut discrimination between the immunophenotype of histiocytic neoplasms and amelanotic melanoma, because of CD68 (show CD68 Proteins) immunoreactivity occurring in 75% of metastatic malignant melanomas

  4. Serum S100B protein levels increased after general anaesthesia. The values of S100Bp (median 164.0 ng/L) were significantly higher than the values of S100Bb (median 94.5 ng/L). The median of the difference between S100Bp and S100Bb was 58.0 ng/L. There were statistically significant differences between S100Bb and S100Bp.

  5. Although an elevation in S100B was not observed in this (second) ascent during re-exposure to the hypobaric hypoxia of high altitude for either the non-treated (acclimatised) or the dexamethasone treated (acclimatised and dexamethasone) groups, the hypothesis that S100B would reduce following acclimatisation could not be statistically confirmed in our study given the wide confidence intervals and small sample size

  6. Serum S100B is a useful quantitative biomarker in routine follow-up of high-risk melanoma patients.

  7. There was no association found between serum and CSF (show CSF2 Proteins) S100B with radiographic vasospasm or DIND. S100B is a potential prognostic marker for aSAH (show ASAH1 Proteins) outcome

  8. Fetuses of active smoker mothers had lower cord blood S100B levels compared to fetuses of non-smoker mothers.

  9. This study inquires into the physiological concentrations of NSE (show ENO2 Proteins) and S100B proteins in CSF (show CSF2 Proteins), carried out on a sufficiently large group of 601 patients.

  10. Studied circulating S100B and adiponectin (show ADIPOQ Proteins) in children who underwent open heart surgery. S100B showed a significant increase from hospital admission up to 24 h after procedure.

Cow (Bovine) S100 Calcium Binding Protein B (S100B) interaction partners

  1. As CSF (show CSF2 Proteins)-S100B levels in calves with neurologic diseases widely differed, the utility of CSF (show CSF2 Proteins)-S100B as a diagnostic marker for neurologic diseases in cattle remains inconclusive.

  2. S100B might participate in the pathophysiology of brain inflammatory disorders via RAGE (show AGER Proteins)-dependent regulation of several inflammation-related events including activation and migration of microglia

  3. X-ray crystallography was used here to characterize an interaction between Ca(2 (show CA2 Proteins))(+)-S100B and TRTK-12, a target that binds to the p53 (show TP53 Proteins)-binding site on S100B.

  4. Intracellular S100B might modulate myoblast differentiation by interfering with MyoD (show MYOD1 Proteins) expression in an NF-kappaB (show NFKB1 Proteins)-dependent manner.

  5. S100b activates guanylate cyclase in a calcium-dependent manner [review]

  6. Structural studies in combination with biochemical data are used to develop a model for calcium-induced activation of human nuclear serine/threonine kinase (NDR (show STK38 Proteins)) kinase by S100B.

  7. S100B shows a sufficient thermostability to resist pasteurization but not spry-drying in milk formulas for preterm and term infants.

  8. Structures of pentamidine (Pnt (show ETS2 Proteins)) bound to Ca(2 (show CA2 Proteins)+)-loaded and Zn(2+),Ca(2 (show CA2 Proteins)+)-loaded S100B were determined by X-ray crystallography at 2.15 A (R(free)=0.266) and 1.85 A (R(free)=0.243) resolution, respectively.

Rabbit S100 Calcium Binding Protein B (S100B) interaction partners

  1. The time course of S100B serum values following spinal cord decompression correlates with outcome; the initial degree of paresis is not a prognostic factor to predict outcome.

s100b (S100B) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21\; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

Alternative names and synonyms associated with s100b (S100B)

  • S100 calcium binding protein A1 (S100a1)
  • S100 calcium binding protein B (S100B)
  • S100 calcium binding protein B (S100b)
  • S100 protein, beta polypeptide, neural (S100b)
  • AI266795 protein
  • AI850290 protein
  • Bpb protein
  • NEF protein
  • S100 protein
  • S100-B protein
  • S100a protein
  • S100beta protein
  • S100P protein

Protein level used designations for S100B

S-100 protein alpha chain , S-100 protein subunit alpha , S100 calcium-binding protein A1 , protein S100-A1 , S-100 calcium-binding protein, beta chain , S-100 protein subunit beta , S100 calcium-binding protein, beta (neural) , protein S100-B , S-100 protein beta chain , S100 calcium-binding protein B , S100 protein, beta polypeptide , S-100 calcium-binding protein beta subunit , S100 calcium-binding protein beta (neural) , S100 protein, beta polypeptide, neural , S100 calcium binding protein, beta (neural) , S100 calcium-binding protein, beta

20193 Mus musculus
6285 Homo sapiens
101099488 Felis catus
100533204 Sus scrofa
525716 Bos taurus
100009495 Oryctolagus cuniculus
25742 Rattus norvegicus
424038 Gallus gallus
100726901 Cavia porcellus
491615 Canis lupus familiaris
101113190 Ovis aries
20203 Mus musculus
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