Browse our anti-TACR1 (TACR1) Antibodies

Full name:
anti-Tachykinin Receptor 1 Antibodies (TACR1)
On are 152 Tachykinin Receptor 1 (TACR1) Antibodies from 26 different suppliers available. Additionally we are shipping TACR1 Kits (43) and TACR1 Proteins (11) and many more products for this protein. A total of 212 TACR1 products are currently listed.
ASPR, nk1R, NKIR, Spr, Tac1r, Tacr1
list all antibodies Gene Name GeneID UniProt
TACR1 6869 P25103
TACR1 21336 P30548
TACR1 24807 P14600

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Top referenced anti-TACR1 Antibodies

  1. Human Polyclonal TACR1 Primary Antibody for ICC, FACS - ABIN152468 : Lai, Ho, Kilpatrick, Wang, Tuluc, Korchak, Douglas: Full-length and truncated neurokinin-1 receptor expression and function during monocyte/macrophage differentiation. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)
    Show all 35 references for 152468

  2. Guinea Pig Polyclonal TACR1 Primary Antibody for ICC, IHC (fro) - ABIN152451 : Anderson, Seybold: Phosphorylated cAMP response element binding protein increases in neurokinin-1 receptor-immunoreactive neurons in rat spinal cord in response to formalin-induced nociception. in Neuroscience letters 2000 (PubMed)
    Show all 30 references for 152451

  3. Human Monoclonal TACR1 Primary Antibody for ELISA - ABIN395116 : Pinheiro, Bulik, Thornton, Sullivan, Root, Bloss, Berrettini, Schork, Kaye, Bergen, Magistretti, Brandt, Crawford, Crow, Fichter, Goldman, Halmi, Johnson, Kaplan, Keel, Klump, La Via, Mitchell, Strober, Rotondo, Treasure, Woodside: Association study of 182 candidate genes in anorexia nervosa. in American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010 (PubMed)
    Show all 5 references for 395116

  4. Human Polyclonal TACR1 Primary Antibody for ICC, IF - ABIN261566 : Cavanaugh, Lee, Lo, Shields, Zylka, Basbaum, Anderson: Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli. in Proceedings of the National Academy of Sciences of the United States of America 2009 (PubMed)

  5. Human Polyclonal TACR1 Primary Antibody for WB - ABIN657820 : Saus, Brunet, Armengol, Alonso, Crespo, Fernández-Aranda, Guitart, Martín-Santos, Menchón, Navinés, Soria, Torrens, Urretavizcaya, Vallès, Gratacòs, Estivill: Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients. in Journal of psychiatric research 2010 (PubMed)

  6. Human Polyclonal TACR1 Primary Antibody for ELISA, WB - ABIN1535783 : Gerard, Garraway, Eddy, Shows, Iijima, Paquet, Gerard: Human substance P receptor (NK-1): organization of the gene, chromosome localization, and functional expression of cDNA clones. in Biochemistry 1991 (PubMed)

More Antibodies against TACR1 Interaction Partners

Human Tachykinin Receptor 1 (TACR1) interaction partners

  1. Expression substance P/neurokinin A (show TAC1 Antibodies)/hemokinin-1 and their preferred neurokinin 1/neurokinin 2 (show TAC1 Antibodies) receptors are dysregulated in uterine leiomyomata.

  2. results suggest that ARRB1 (show ARRB1 Antibodies) plays an essential role in NK1R-mediated cell proliferation and G2/M transition in glioblastoma cells. Interference with ARRB1 (show ARRB1 Antibodies)-mediated signaling via NK1R may have potential significance for therapeutic strategies targeting glioblastoma.

  3. Data suggest that endogenous tachykinin ligands for neurokinin-1 receptor exhibit large variations in binding/activation kinetics; substance P (show TAC1 Antibodies) exhibits fast association kinetics; neurokinin A (show TAC1 Antibodies) exhibits slow association kinetics.

  4. We showed that pretreating a cardiomyocyte cell line (H9C2) and a TNBC cell line (MDA-MB 231) with aprepitant, a SP receptor antagonist that is routinely used to treat chemotherapy-associated nausea, decreased DOX-induced reduction of viability, apoptotic cell death, and ROS (show ROS1 Antibodies) production in cardiomyocytes

  5. These findings reveal important insight into the molecular mechanisms of the NK1R complex as a critical component in a model of pediatric liver cancer and may support the development of novel therapeutic interventions for hepatoblastoma

  6. Neuropeptide signaling through neurokinin-1 (show TAC1 Antibodies) and neurokinin-2 (show TAC1 Antibodies) receptors augments antigen presentation by human dendritic cells

  7. Inhibition of CaV2.3 (show CACNA1E Antibodies) channels by NK1 (show CD160 Antibodies) receptors is sensitive to membrane cholesterol but insensitive to caveolin-1 (show CAV1 Antibodies).

  8. NK-1 (show CD160 Antibodies) activation could enhance EGFR (show EGFR Antibodies) expression and phosphorylation, and then activate EGFR (show EGFR Antibodies) related Erk/MAPK (show MAPK1 Antibodies) and Akt (show AKT1 Antibodies) pathway.

  9. The single nucleotide polymorphisms in the TACR1 gene are associated with sex differences in postoperative nausea and vomiting.

  10. Results show the existence of a relevant alteration in NK-1R expression in bipolar disorder patients and further suggest Substance P (show TAC1 Antibodies) involvement in BD.

Mouse (Murine) Tachykinin Receptor 1 (TACR1) interaction partners

  1. results indicate the contribution of NK1R signaling in maintaining the homeostasis of the ocular surface under steady-state condition, and that the lack of functional NK1R increases the susceptibility of eyes to develop severe herpes stromal keratitis upon ocular HSV-1 infection

  2. the NK1R-CreER mouse line is a valuable new tool for conditional gene manipulation enabling the visualization and manipulation of cells that express NK1R.

  3. NK1R-/- mice did not exhibit excessive false alarms, compared with wildtypes (response disinhibition) but, as in the 5-Choice ContinuousPerformance Test, they exhibited more perseverative responses throughout the test

  4. NK1R-expressing dorsal horn neurons play a major role in the expression of symptoms of chronic itch.

  5. The results of this study indicated that certain behaviours, disrupted in ADHD, are influenced by an interaction between the BRAS and NK1R, and suggest that ACE (show ACE Antibodies) inhibitors could provide a novel treatment for this disorder.

  6. Results provide evidence linking enhanced waking activity and the pro-inflammatory molecule substance P (show TAC1 Antibodies) to changes in slow-wave activity associated with sleep-active cortical cells that co-express nNOS (show NOS1 Antibodies) and the NK-1R

  7. the hyperactivity, perseveration and, possibly, inattentiveness of NK1R-/- mice is a direct consequence of a lack of functional NK1R

  8. Substance P (show TAC1 Antibodies) partly accounts for the increased density of microglia in the substantia nigra through chemotaxic recruitment via a novel NK1R-NOX2 (show CYBB Antibodies) axis-mediated pathway.

  9. NK1 (show HGF Antibodies)-R expression in the trachea, bronchus, and lung tissue increased in MP-infected BALB/c mice, which may explain why wheezing occurs after MP infection.

  10. The behavioural response of mice lacking NK1r to guanfacine resembles its clinical profile in treatment of ADHD

Rabbit Tachykinin Receptor 1 (TACR1) interaction partners

  1. Implanting vascular bundles into the tissue engineered bone can significantly improve the expression levels of NK1R and VIPR1 (show VIPR1 Antibodies).

Guinea Pig Tachykinin Receptor 1 (TACR1) interaction partners

  1. Activation of neurokinin-1 (show TAC1 Antibodies) receptors in primary sensory neurons plays a role in the generation of overactive bladder.

  2. Substance P (show TAC1 Antibodies) and SP-R mRNA expressions were reduced after IMETIT treatment of allergic rhinitis.

TACR1 Antigen Profile

Antigen Summary

This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P.

Alternative names and synonyms associated with TACR1

  • substance-P receptor-like (LOC100053491) antibody
  • tachykinin receptor 1 (TACR1) antibody
  • tachykinin receptor 1 (Tacr1) antibody
  • ASPR antibody
  • nk1R antibody
  • NKIR antibody
  • Spr antibody
  • Tac1r antibody
  • Tacr1 antibody

Protein level used designations for TACR1

NK-1 receptor , NK-1R , substance-P receptor , tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor) , Nk1 receptor , neurokinin receptor 1 , substance P receptor , SPR , neurokinin 1 receptor , substance p receptor , neurokinin receptor subtype NK1 , tachikinin receptor 1 , tachykinin receptor 1 , neurokinin-1 receptor

100053491 Equus caballus
6869 Homo sapiens
21336 Mus musculus
24807 Rattus norvegicus
403815 Canis lupus familiaris
407133 Bos taurus
100357296 Oryctolagus cuniculus
100135626 Cavia porcellus
395677 Gallus gallus
101122011 Ovis aries
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