Browse our AQP2 Proteins (AQP2)

Full name:
Aquaporin 2 (Collecting Duct) Proteins (AQP2)
On are 7 Aquaporin 2 (Collecting Duct) (AQP2) Proteins from 5 different suppliers available. Additionally we are shipping AQP2 Antibodies (184) and AQP2 Kits (46) and many more products for this protein. A total of 242 AQP2 products are currently listed.
AQP-2, AQP-CD, aquaporin-2, cph, jpk, WCH-CD
list all proteins Gene Name GeneID UniProt
AQP2 11827 P56402
AQP2 25386 P34080
AQP2 359 P41181

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AQP2 Proteins (AQP2) by Origin

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More Proteins for AQP2 Interaction Partners

Mouse (Murine) Aquaporin 2 (Collecting Duct) (AQP2) interaction partners

  1. Ativation of LXRbeta (show NR1H2 Proteins) increases AQP2 protein levels in the renal collecting ducts via a posttranscriptional mechanism top regulate water electrolyte balance.

  2. PDZ domain-containing protein Sipa1l1 (signal-induced proliferation-associated 1 like 1) binds to the cytoplasmic PDZ-ligand motif of aquaporin-2 and accelerates its endocytosis in the absence of vasopressin

  3. Conditional inactivation of Elf5 in the developing collecting ducts results in a small but significant reduction in the expression levels of Aqp2 and Avpr2 genes.

  4. These results provide the direct evidence that the Ser (show SIGLEC1 Proteins)-261 dephosphorylation is involved in the pS256- and pS269-related AQP2 regulation.

  5. analysis of phosphorylation-dependent interactions of AQP2 with 14-3-3theta; and -zeta

  6. the activation of CaSR (show CASR Proteins) in the collecting duct prevents the cyclic AMP (show TMPRSS5 Proteins)-dependent increase in AQP2-phosphorylation at S256 and water permeability, counteracting the short-term vasopressin (show AVP Proteins) response.

  7. Functional photoconvertible chimeric AQP-2 was successfully expressed in mpkCCD cells, in which forskolin induced apical trafficking and accumulation of chimeric AQP-2.

  8. Suggest ERalpha (show ESR1 Proteins) in mediates the inhibitory effect of estradiol on AQP2 expression in collecting ducts.

  9. Data suggest that the ability of prostaglandin E2 receptor EP4 (show PTGER4 Proteins) to promote aquaporin 2 (AQP2) membrane targeting and increase AQP2 abundance makes it a therapeutic target for the treatment of congenital diabetes insipidus.

  10. Odontoblast-lineage cell line have high-cell viability under xylitol-induced hypertonic stress, which may be associated with TRPV1 (show TRPV1 Proteins) and AQP2 expressions.

Human Aquaporin 2 (Collecting Duct) (AQP2) interaction partners

  1. An overview ofAQP2 mutations in genetic forms of nephrogenic diabetes insipidus (review)

  2. Impaired endometrial receptivity in patients who underwent controlled ovarian stimulation is correlated with a decreased expression of AQP2.

  3. Pretreatment with alkali (0.4 N NaOH) to disrupt exosome membranes allowed consistent ELISA measurements of urinary AQP2.

  4. Findings indicate that SIRT1 (show SIRT1 Proteins) increases AQP2 expression in TNF-alpha (show TNF Proteins)-induced IMCD cells via the NF-kappaB (show NFKB1 Proteins)-dependent signalling pathway, which might provide novel insight to understanding the renoprotective effects of SIRT1 (show SIRT1 Proteins) in kidney diseases.

  5. AQP2 polymorphisms (rs461872, rs7305534) were correlated with gastrointestinal toxicity of platinum-based chemotherapy in lung cancer patients

  6. report a novel mutation of the AQP2 gene and highlight an important role of genetic testing for definite diagnosis

  7. The study demonstrated the abnormal expression pattern of AQP1 (show AQP1 Proteins), AQP2, AQP3 (show AQP3 Proteins), and AQP4 (show AQP4 Proteins) in the kidney tissues of patients with nephrotic syndrome, providing a basis for an improved understanding of the role of aquaporins in the pathogenesis of this disease.

  8. In most cases (90 %), inherited nephrogenic diabetes insipidus (NDI) is an X-linked disease, caused by mutations in the AVPR2 gene. * In rare occasions (10 %), it is caused by mutations in the AQP2 gene.

  9. Partial congenital nephrogenic diabetes insipidus in the Swedish family is caused by an AQP2 variation that seems to disable the encoded AQP2-R254W protein to reach the subapical vesicle population as well as impairing its phosphorylation at S256

  10. Taken together these results provide a possible molecular mechanism explaining the increased AQP2 membrane expression under RGZ treatment: in renal cells RGZ elicits Ca(2 (show CA2 Proteins)+) transients facilitating AQP2 exposure at the apical plasma membrane

Pig (Porcine) Aquaporin 2 (Collecting Duct) (AQP2) interaction partners

  1. Aquaporin 2 promotes cell migration and epithelial morphogenesis.

  2. Data provide evidence supporting the role of S256 and S269 in the maintenance of AQP2 at the cell surface.

AQP2 Protein Profile

Protein Summary

This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus.

Alternative names and synonyms associated with AQP2

  • aquaporin 2 (Aqp2)
  • aquaporin 2 (LOC100352066)
  • aquaporin 2 (collecting duct) (Aqp2)
  • aquaporin 2 (collecting duct) (AQP2)
  • AQP-2 protein
  • AQP-CD protein
  • aquaporin-2 protein
  • cph protein
  • jpk protein
  • WCH-CD protein

Protein level used designations for AQP2

ADH water channel , AQP-2 , aquaporin-2 , aquaporin-CD , collecting duct water channel protein , water channel protein for renal collecting duct , AQP-CD , WCH-CD , water-channel aquaporin 2 , Aquaporin-2

11827 Mus musculus
100352066 Oryctolagus cuniculus
25386 Rattus norvegicus
431304 Gallus gallus
359 Homo sapiens
486552 Canis lupus familiaris
539870 Bos taurus
443024 Ovis aries
100147810 Sus scrofa
100722014 Cavia porcellus
100059758 Equus caballus
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