Browse our anti-Calreticulin (CALR) Antibodies

Full name:
anti-Calreticulin Antibodies (CALR)
On www.antibodies-online.com are 302 Calreticulin (CALR) Antibodies from 31 different suppliers available. Additionally we are shipping Calreticulin Kits (61) and Calreticulin Proteins (49) and many more products for this protein. A total of 431 Calreticulin products are currently listed.
Synonyms:
anon-EST:fe3D7, anon-EST:Liang-2.11, anon-EST:Liang-2.17, CALR, Calregulin, cC1qR, CG9429, clone 2.11, clone 2.17, Clr, crc, CRP55, CRT, Dmel\\CG9429, ERp60, eth, HACBP, NV19007, potp, RO, SSA, zgc:85636

Most Popular Reactivities for anti-Calreticulin (CALR) Antibodies

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anti-Human Calreticulin Antibodies:

anti-Mouse (Murine) Calreticulin Antibodies:

anti-Rat (Rattus) Calreticulin Antibodies:

All available anti-Calreticulin Antibodies

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Top referenced anti-Calreticulin Antibodies

  1. Human Monoclonal Calreticulin Primary Antibody for WB - ABIN394076 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for 394076

  2. Human Monoclonal Calreticulin Primary Antibody for IF, WB - ABIN968752 : Ito, Seyama, Kubota: Calreticulin is directly involved in anti-alpha3 integrin antibody-mediated secretion and activation of matrix metalloprotease-2. in Biochemical and biophysical research communications 2001 (PubMed)
    Show all 4 references for 968752

  3. Dog (Canine) Polyclonal Calreticulin Primary Antibody for IF, IHC (p) - ABIN265295 : Kageyama, Isono, Matsuda, Ushio, Satomura, Terai, Arai, Kawakita, Okada, Yoshiki: Urinary calreticulin in the diagnosis of bladder urothelial carcinoma. in International journal of urology : official journal of the Japanese Urological Association 2009 (PubMed)
    Show all 3 references for 265295

  4. Human Polyclonal Calreticulin Primary Antibody for FACS, IF (p) - ABIN759731 : Chen, Wu, Xu, Xu: Calreticulin Binds to Fas Ligand and Inhibits Neuronal Cell Apoptosis Induced by Ischemia-Reperfusion Injury. in BioMed research international 2015 (PubMed)
    Show all 3 references for 759731

  5. Dog (Canine) Polyclonal Calreticulin Primary Antibody for IHC, WB - ABIN2779285 : Urade, Okudo, Kato, Moriyama, Arakaki: ER-60 domains responsible for interaction with calnexin and calreticulin. in Biochemistry 2004 (PubMed)
    Show all 2 references for 2779285

  6. Human Monoclonal Calreticulin Primary Antibody for ICC, IHC - ABIN1724687 : Tan, Chen, Li, Mabuchi, Bouvier: The calcium- and zinc-responsive regions of calreticulin reside strictly in the N-/C-domain. in Biochimica et biophysica acta 2006 (PubMed)

  7. Human Polyclonal Calreticulin Primary Antibody for FACS, IF (p) - ABIN886210 : Angelova, Grekova, Heller, Kuhlmann, Soyka, Giese, Aprahamian, Bour, Rüffer, Cziepluch, Daeffler, Rommelaere, Werner, Raykov, Giese: Complementary induction of immunogenic cell death by oncolytic parvovirus H-1PV and gemcitabine in pancreatic cancer. in Journal of virology 2014 (PubMed)

  8. Human Polyclonal Calreticulin Primary Antibody for FACS, IHC (p) - ABIN390885 : Alur, Nguyen, Eggener, Jiang, Dadras, Stern, Kimm, Roehl, Kozlowski, Pins, Michalak, Dhir, Wang: Suppressive roles of calreticulin in prostate cancer growth and metastasis. in The American journal of pathology 2009 (PubMed)

More Antibodies against Calreticulin Interaction Partners

Fruit Fly (Drosophila melanogaster) Calreticulin (CALR) interaction partners

  1. Calreticulin plays a key role in olfactory system function, possibly by establishing its overall sensitivity to odorants.

  2. Calreticulin mediates hypersensitivity to diethylether and resistance to isoflurane in association with low expression of the gene.

  3. These results collectively indicate that calreticulin is the first molecule to be identified as a marker for phagocytosis of apoptotic cells by Drosophila phagocytes

Human Calreticulin (CALR) interaction partners

  1. Mannan-binding lectin (MBL (show MBL2 Antibodies)) bound to T cells through interaction between the collagen-like region of MBL (show MBL2 Antibodies) and calreticulin (CRT) expressed on the T-cell surface.

  2. CRT (show SLC6A8 Antibodies) exposure represents a novel powerful prognostic biomarker for patients with acute myeloid leukemia (show BCL11A Antibodies).

  3. In absence of CALR, immature MPO (show MPO Antibodies) protein precursors are degraded in the proteasome.

  4. In patients with HD, a panel using calretinin and peripherin with or without MAP-2 may be most helpful in identifying transition zones

  5. Coexisting mutations of the JAK2 (show JAK2 Antibodies), CALR, and MPL (show MPL Antibodies) genes in myeloproliferative neoplasms suggest that CALR and MPL (show MPL Antibodies) should be analyzed not only in JAK2 (show JAK2 Antibodies)-negative patients but also in low V617F mutation patients.

  6. CALR-mutated essential thrombocythemia (ET) patients harbored a higher mutant load at progenitor level than JAK2V617F-positive ET (HSCs: 39.9% vs 7.5% p<0.001, hematopoietic stem cells)

  7. Results indicate that NGF (show NGFB Antibodies) inhibited CRT (show SLC6A8 Antibodies) translocation induced by mitoxantrone. NGF (show NGFB Antibodies) effect on CRT (show SLC6A8 Antibodies) translocation could have consequences in immunotherapy, potentially lessening the effectiveness of this type of treatment.

  8. The consistent association between Calr and Dio2 (show DIO2 Antibodies) expression suggests that enhanced expression of these two genes facilitate detrimental effects on cartilage integrity.

  9. The myeloproliferative neoplasms (MPNs) patients carrying Calreticulin(CALR) mutations presented with higher platelet counts and lower hemoglobin (show HBB Antibodies) levels compared to those with mutated JAK2 (show JAK2 Antibodies). However, all of the leukemia patients had negative results for CALR mutations.

  10. Alterated IQGAP1 (show IQGAP1 Antibodies)/Rho GTPase (show RACGAP1 Antibodies) signaling in myeloproliferative neoplasm erythrocytes is dependent on JAK2 (show JAK2 Antibodies)/CALR mutational status.

Rabbit Calreticulin (CALR) interaction partners

  1. These findings suggest that protein kinase C (show PKC Antibodies) is involved in the regulation of CRT function.

Mouse (Murine) Calreticulin (CALR) interaction partners

  1. study provides a model showing that the C-terminal of mutant CALR activated JAK (show JAK3 Antibodies)-STAT (show STAT1 Antibodies) signaling specifically downstream of MPL (show MPL Antibodies) and may have a central role in CALR-induced myeloproliferative neoplasms

  2. the results of this investigation provide the first molecular insights into the phospholipid binding site of calreticulin as a key anchor point for the cell surface expression of calreticulin on apoptotic cells

  3. a profound impairment in calreticulin function when its lectin site was inactivated. Remarkably, inactivation of the polypeptide binding site had little impact. These findings indicate that the lectin-based mode of client interaction is the predominant contributor to the chaperone functions of calreticulin within the endoplasmic reticulum.

  4. This essential role of calreticulin in nucleocytoplasmic communication competency ties its regulatory action with proficiency of cardiac myofibrillogenesis essential for proper cardiac development.

  5. Study provides evidence that chronic stress activates calreticulin and might be one of the pathological mechanisms underlying the motor coordination and motor learning dysfunctions seen in social defeat mice.

  6. This study for the first time revealed that increased CRT (show SLC6A8 Antibodies) inhibited Fas (show FAS Antibodies)/FasL (show FASL Antibodies)-mediated neuronal cell apoptosis during the early stage of ischemic stroke, suggesting it to be a potential protector activated soon after ischemia-reperfusion injury

  7. The findings highlight the importance of CALR in female reproduction and demonstrate that compromised CALR function leads to ovarian insufficiency and female infertility.

  8. Calreticulin mediates vascular smooth muscle cell responses to injury through the regulation of collagen deposition and neointima formation.

  9. CALR mutants are sufficient to induce thrombocytosis through MPL (show MPL Antibodies) activation.

  10. Thrombopoietin receptor (show MPL Antibodies) activation by myeloproliferative neoplasm associated calreticulin mutants.

Cow (Bovine) Calreticulin (CALR) interaction partners

  1. the lectin site of CRT is the main target for gentamicin binding

Pig (Porcine) Calreticulin (CALR) interaction partners

  1. Calreticulin is confined to subplasmalemmal vesicles partially overlapping with cortical granule contents. Its exocytosis after the oocyte activation seems to participate in the membrane block to polyspermy in pigs.

  2. Calreticulin was widely expressed in pig tissues and its transcripts were downregulated during maturation, especially at 44 hr, and were undetectable at the blastocyst stage.

Calreticulin (CALR) Antigen Profile

Antigen Summary

Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium. The amino terminus of calreticulin interacts with the DNA-binding domain of the glucocorticoid receptor and prevents the receptor from binding to its specific glucocorticoid response element. Calreticulin can inhibit the binding of androgen receptor to its hormone-responsive DNA element and can inhibit androgen receptor and retinoic acid receptor transcriptional activities in vivo, as well as retinoic acid-induced neuronal differentiation. Thus, calreticulin can act as an important modulator of the regulation of gene transcription by nuclear hormone receptors. Systemic lupus erythematosus is associated with increased autoantibody titers against calreticulin but calreticulin is not a Ro/SS-A antigen. Earlier papers referred to calreticulin as an Ro/SS-A antigen but this was later disproven. Increased autoantibody titer against human calreticulin is found in infants with complete congenital heart block of both the IgG and IgM classes.

Alternative names and synonyms associated with Calreticulin (CALR)

  • calreticulin (calr) antibody
  • calreticulin (crt) antibody
  • calreticulin (CRT) antibody
  • Calreticulin (Crc) antibody
  • calreticulin (LmjF31.2600) antibody
  • calreticulin (Crc) antibody
  • calreticulin (CALR) antibody
  • calreticulin (Calr) antibody
  • calreticulin (Crt) antibody
  • calreticulin 2, calcium-binding protein (CRT2) antibody
  • calreticulin 3 (CALR3) antibody
  • anon-EST:fe3D7 antibody
  • anon-EST:Liang-2.11 antibody
  • anon-EST:Liang-2.17 antibody
  • CALR antibody
  • Calregulin antibody
  • cC1qR antibody
  • CG9429 antibody
  • clone 2.11 antibody
  • clone 2.17 antibody
  • Clr antibody
  • crc antibody
  • CRP55 antibody
  • CRT antibody
  • Dmel\\CG9429 antibody
  • ERp60 antibody
  • eth antibody
  • HACBP antibody
  • NV19007 antibody
  • potp antibody
  • RO antibody
  • SSA antibody
  • zgc:85636 antibody

Protein level used designations for anti-Calreticulin (CALR) Antibodies

calreticulin , CG9429-PA , CG9429-PB , Crc-PA , Crc-PB , anon-fast-evolving-3D7 , pot pourri , potpourri , ER-resident chaperone calreticulin , CRP55 , ERp60 , HACBP , Sicca syndrome antigen A (autoantigen Ro; calreticulin) , calregulin , endoplasmic reticulum resident protein 60 , grp60 , CABP3 , CALBP , calcium-binding protein 3 , calrectulin , Endoplasmic reticulum resident protein 60

GENE ID SPECIES
379788 Xenopus laevis
100136202 Oncorhynchus mykiss
100146083 Triticum aestivum
30248 Danio rerio
41166 Drosophila melanogaster
407962 Xenopus (Silurana) tropicalis
5654192 Leishmania major strain Friedlin
100116123 Nasonia vitripennis
100304608 Ictalurus punctatus
811 Homo sapiens
476694 Canis lupus familiaris
100009050 Oryctolagus cuniculus
12317 Mus musculus
64202 Rattus norvegicus
281036 Bos taurus
100381266 Sus scrofa
101104396 Ovis aries
100713922 Cavia porcellus
692629 Bombyx mori
100689096 Cricetulus griseus
5715514 Chlamydomonas reinhardtii
420146 Gallus gallus
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