Browse our anti-SLC6A8 (SLC6A8) Antibodies

Full name:
anti-Solute Carrier Family 6 (Neurotransmitter Transporter, Creatine), Member 8 Antibodies (SLC6A8)
On www.antibodies-online.com are 43 Solute Carrier Family 6 (Neurotransmitter Transporter, Creatine), Member 8 (SLC6A8) Antibodies from 15 different suppliers available. Additionally we are shipping SLC6A8 Kits (15) and SLC6A8 Proteins (4) and many more products for this protein. A total of 69 SLC6A8 products are currently listed.
Synonyms:
AA589632, Calregulin, cC1qR, CCDS1, CHOT1, CHT1, Creat, CRT, CRTR, CT1, RO, SLC6A8, SSA
list all antibodies Gene Name GeneID UniProt
SLC6A8 811 P27797
SLC6A8 12317 P14211
SLC6A8 50690 P28570

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Most Popular Reactivities for anti-SLC6A8 (SLC6A8) Antibodies

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anti-Human SLC6A8 Antibodies:

anti-Mouse (Murine) SLC6A8 Antibodies:

anti-Rat (Rattus) SLC6A8 Antibodies:

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Top referenced anti-SLC6A8 Antibodies

  1. Human Polyclonal SLC6A8 Primary Antibody for ELISA, WB - ABIN1451640 : Sandoval, Bauer, Brenner, Coy, Drescher, Kioschis, Korn, Nyakatura, Poustka, Reichwald, Rosenthal, Platzer: The genomic organization of a human creatine transporter (CRTR) gene located in Xq28. in Genomics 1996 (PubMed)

  2. Cow (Bovine) Polyclonal SLC6A8 Primary Antibody for IHC, WB - ABIN2775317 : Dodd, Christie: Substituted cysteine accessibility of the third transmembrane domain of the creatine transporter: defining a transport pathway. in The Journal of biological chemistry 2005 (PubMed)

  3. Cow (Bovine) Polyclonal SLC6A8 Primary Antibody for WB - ABIN2775318 : Anselm, Coulter, Darras: Cardiac manifestations in a child with a novel mutation in creatine transporter gene SLC6A8. in Neurology 2008 (PubMed)

More Antibodies against SLC6A8 Interaction Partners

Human Solute Carrier Family 6 (Neurotransmitter Transporter, Creatine), Member 8 (SLC6A8) interaction partners

  1. C-CALR (show CALR Antibodies) in response to Ca2 (show CA2 Antibodies)+ undergoes conformational changes that trigger its function to export GR from the nucleus, resetting the stress response of normal erythroid cells. Impairment of this function in JAK2V617F-positive erythroid cells maintains EPO-R (show EPOR Antibodies) signaling in proliferation mode, contributing to erythrocytosis in PV.

  2. Mannan-binding lectin (MBL (show MBL2 Antibodies)) bound to T cells through interaction between the collagen-like region of MBL (show MBL2 Antibodies) and calreticulin (CRT (show CALR Antibodies)) expressed on the T-cell surface.

  3. CRT exposure represents a novel powerful prognostic biomarker for patients with acute myeloid leukemia (show BCL11A Antibodies).

  4. In absence of CALR (show CALR Antibodies), immature MPO (show MPO Antibodies) protein precursors are degraded in the proteasome.

  5. In patients with HD, a panel using calretinin and peripherin with or without MAP-2 may be most helpful in identifying transition zones

  6. Coexisting mutations of the JAK2 (show JAK2 Antibodies), CALR (show CALR Antibodies), and MPL (show MPL Antibodies) genes in myeloproliferative neoplasms suggest that CALR (show CALR Antibodies) and MPL (show MPL Antibodies) should be analyzed not only in JAK2 (show JAK2 Antibodies)-negative patients but also in low V617F mutation patients.

  7. CALR (show CALR Antibodies)-mutated essential thrombocythemia (ET) patients harbored a higher mutant load at progenitor level than JAK2V617F-positive ET (HSCs: 39.9% vs 7.5% p<0.001, hematopoietic stem cells)

  8. Results indicate that NGF (show NGFB Antibodies) inhibited CRT translocation induced by mitoxantrone. NGF (show NGFB Antibodies) effect on CRT translocation could have consequences in immunotherapy, potentially lessening the effectiveness of this type of treatment.

  9. The consistent association between Calr (show CALR Antibodies) and Dio2 (show DIO2 Antibodies) expression suggests that enhanced expression of these two genes facilitate detrimental effects on cartilage integrity.

  10. The myeloproliferative neoplasms (MPNs) patients carrying Calreticulin(CALR (show CALR Antibodies)) mutations presented with higher platelet counts and lower hemoglobin (show HBB Antibodies) levels compared to those with mutated JAK2 (show JAK2 Antibodies). However, all of the leukemia patients had negative results for CALR (show CALR Antibodies) mutations.

Mouse (Murine) Solute Carrier Family 6 (Neurotransmitter Transporter, Creatine), Member 8 (SLC6A8) interaction partners

  1. study provides a model showing that the C-terminal of mutant CALR (show CALR Antibodies) activated JAK (show JAK3 Antibodies)-STAT (show STAT1 Antibodies) signaling specifically downstream of MPL (show MPL Antibodies) and may have a central role in CALR (show CALR Antibodies)-induced myeloproliferative neoplasms

  2. the results of this investigation provide the first molecular insights into the phospholipid binding site of calreticulin (show CALR Antibodies) as a key anchor point for the cell surface expression of calreticulin (show CALR Antibodies) on apoptotic cells

  3. a profound impairment in calreticulin (show CALR Antibodies) function when its lectin site was inactivated. Remarkably, inactivation of the polypeptide binding site had little impact. These findings indicate that the lectin-based mode of client interaction is the predominant contributor to the chaperone functions of calreticulin (show CALR Antibodies) within the endoplasmic reticulum.

  4. This essential role of calreticulin (show CALR Antibodies) in nucleocytoplasmic communication competency ties its regulatory action with proficiency of cardiac myofibrillogenesis essential for proper cardiac development.

  5. Study provides evidence that chronic stress activates calreticulin (show CALR Antibodies) and might be one of the pathological mechanisms underlying the motor coordination and motor learning dysfunctions seen in social defeat mice.

  6. This study for the first time revealed that increased CRT inhibited Fas (show FAS Antibodies)/FasL (show FASL Antibodies)-mediated neuronal cell apoptosis during the early stage of ischemic stroke, suggesting it to be a potential protector activated soon after ischemia-reperfusion injury

  7. The findings highlight the importance of CALR (show CALR Antibodies) in female reproduction and demonstrate that compromised CALR (show CALR Antibodies) function leads to ovarian insufficiency and female infertility.

  8. Calreticulin (show CALR Antibodies) mediates vascular smooth muscle cell responses to injury through the regulation of collagen deposition and neointima formation.

  9. CALR (show CALR Antibodies) mutants are sufficient to induce thrombocytosis through MPL (show MPL Antibodies) activation.

  10. Thrombopoietin receptor (show MPL Antibodies) activation by myeloproliferative neoplasm associated calreticulin (show CALR Antibodies) mutants.

Cow (Bovine) Solute Carrier Family 6 (Neurotransmitter Transporter, Creatine), Member 8 (SLC6A8) interaction partners

  1. GSK3ss down-regulates the creatine transporter CreaT, an effect reversed by treatment with the antidepressant Lithium and by co-expression of PKB/Akt (show AKT1 Antibodies).

  2. Mammalian target of rapamycin (mTOR (show FRAP1 Antibodies)) stimulates the creatine transporter SLC6A8 through mechanisms at least partially shared by the serum and glucocorticoid-inducible kinase SGK1 (show SGK1 Antibodies).

  3. The observations suggest that SGK1 (show SGK1 Antibodies) regulates the creatine transporter SLC6A8 at least partially through phosphorylation and activation of PIKfyve (show PIKFYVE Antibodies).

SLC6A8 Antigen Profile

Antigen Summary

The protein encoded by this gene is a plasma membrane protein whose function is to transport creatine into and out of cells. Defects in this gene can result in X-linked creatine deficiency syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with SLC6A8

  • solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8) antibody
  • solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (slc6a8) antibody
  • calreticulin (CALR) antibody
  • calreticulin (Calr) antibody
  • solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (Slc6a8) antibody
  • solute carrier family 6 (neurotransmitter transporter), member 8 (SLC6A8) antibody
  • solute carrier family 6 (neurotransmitter transporter), member 8 (Slc6a8) antibody
  • AA589632 antibody
  • Calregulin antibody
  • cC1qR antibody
  • CCDS1 antibody
  • CHOT1 antibody
  • CHT1 antibody
  • Creat antibody
  • CRT antibody
  • CRTR antibody
  • CT1 antibody
  • RO antibody
  • SLC6A8 antibody
  • SSA antibody

Protein level used designations for SLC6A8

solute carrier family 6 (neurotransmitter transporter, creatine), member 8 , Sodium- and chloride-dependent creatine transporter 1 , ct1 , sodium- and chloride-dependent creatine transporter 1-like , CRP55 , ERp60 , HACBP , Sicca syndrome antigen A (autoantigen Ro; calreticulin) , calregulin , endoplasmic reticulum resident protein 60 , grp60 , sodium- and chloride-dependent creatine transporter 1 , CT1 , choline transporter , creatine transporter 1 , solute carrier family 6 member 8 , creatine transporter, solute carrier family 6, member 8 , solute carrier family 6, member 8 , creatine transporter SLC6A8

GENE ID SPECIES
473853 Pan troglodytes
567544 Danio rerio
698307 Macaca mulatta
100127575 Xenopus (Silurana) tropicalis
100404520 Callithrix jacchus
100440816 Pongo abelii
100589275 Nomascus leucogenys
811 Homo sapiens
12317 Mus musculus
492242 Canis lupus familiaris
100302506 Sus scrofa
282367 Bos taurus
100009280 Oryctolagus cuniculus
102857 Mus musculus
6535 Homo sapiens
50690 Rattus norvegicus
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