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Browse our anti-SLC6A8 (SLC6A8) Antibodies

Full name:
anti-Solute Carrier Family 6 (Neurotransmitter Transporter, Creatine), Member 8 Antibodies (SLC6A8)
On www.antibodies-online.com are 42 Solute Carrier Family 6 (Neurotransmitter Transporter, Creatine), Member 8 (SLC6A8) Antibodies from 13 different suppliers available. Additionally we are shipping SLC6A8 Kits (18) and SLC6A8 Proteins (5) and many more products for this protein. A total of 72 SLC6A8 products are currently listed.
Synonyms:
AA589632, Calregulin, cC1qR, CCDS1, CHOT1, CHT1, Creat, CRT, CRTR, CT1, RO, SLC6A8, SSA
list all antibodies Gene Name GeneID UniProt
SLC6A8 811 P27797
SLC6A8 12317 P14211
SLC6A8 50690 P28570

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Most Popular Reactivities for anti-SLC6A8 (SLC6A8) Antibodies

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anti-Human SLC6A8 Antibodies:

anti-Mouse (Murine) SLC6A8 Antibodies:

anti-Rat (Rattus) SLC6A8 Antibodies:

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Top referenced anti-SLC6A8 Antibodies

  1. Human Polyclonal SLC6A8 Primary Antibody for ELISA, WB - ABIN1451640 : Sandoval, Bauer, Brenner, Coy, Drescher, Kioschis, Korn, Nyakatura, Poustka, Reichwald, Rosenthal, Platzer: The genomic organization of a human creatine transporter (CRTR) gene located in Xq28. in Genomics 1996 (PubMed)

  2. Cow (Bovine) Polyclonal SLC6A8 Primary Antibody for IHC, WB - ABIN2775317 : Dodd, Christie: Substituted cysteine accessibility of the third transmembrane domain of the creatine transporter: defining a transport pathway. in The Journal of biological chemistry 2005 (PubMed)

  3. Human Polyclonal SLC6A8 Primary Antibody for WB - ABIN2775318 : Anselm, Coulter, Darras: Cardiac manifestations in a child with a novel mutation in creatine transporter gene SLC6A8. in Neurology 2008 (PubMed)

More Antibodies against SLC6A8 Interaction Partners

Human Solute Carrier Family 6 (Neurotransmitter Transporter, Creatine), Member 8 (SLC6A8) interaction partners

  1. Data show that the median calreticulin (CALR (show CALR Antibodies))mut (show MUT Antibodies) allelic burden at diagnosis was significantly higher in primary myelofibrosis (PMF) patients as compared to essential thrombocythemia (ET) case.

  2. Studies indicate that a genetic classification of primary fibrosis (PMF) by calreticulin (CALR (show CALR Antibodies)) and JAK2V617F (JAK2 (show JAK2 Antibodies))mutations carried significant prognostic relevance.

  3. The present study demonstrated that a novel CRT missense mutation in exon 12 of the SLC6A8 gene (c.1681G>C; p.G561R) causes suppression of creatine transport activity

  4. Mutation status of JAK2 (show JAK2 Antibodies), CALR (show CALR Antibodies), and MPL (show MPL Antibodies) in essential thrombocythemia and primary myelofibrosis defines clinical outcome.

  5. we show that the positive charge of the CALR (show CALR Antibodies) mutant C-terminus is necessary to transform hematopoietic cells by enabling binding between mutant CALR (show CALR Antibodies) and the thrombopoietin receptor MPL (show MPL Antibodies).

  6. CALR (show CALR Antibodies) is not only a potential diagnostic molecular marker but also adds relevant prognostic information as it is associated with milder clinical and haematological characteristics compared to the JAK2V617F-mutated or 'triple-negative' patients.

  7. The incidence of calreticulin (show CALR Antibodies) mutations in essential thrombocythemia and primary myelofibrosis was 24.2% and increased to 50.0% in JAK2 (show JAK2 Antibodies) V617F-negative cases. Essential thrombocythemia patients carrying calreti mutations were younger, showed lower WBC counts, and experienced less thrombosis than did those carrying the JAK2 (show JAK2 Antibodies) V617F mutation, although no differences in other clinical features and prognosis were demonstrated.

  8. Anagrelide proved effective among all molecular subsets, indicating that JAK2 (show JAK2 Antibodies)/CALR (show CALR Antibodies)/MPL (show MPL Antibodies) mutational status does not seem to represent a major determinant of choice of cytoreductive treatment among essential thrombocythemia therapies.

  9. This essential role of calreticulin (show CALR Antibodies) in nucleocytoplasmic communication competency ties its regulatory action with proficiency of cardiac myofibrillogenesis essential for proper cardiac development.

  10. Data suggest that a specific plasma membrane transporter, creatine transporter (SLC6A8), enables cells to incorporate creatine; creatine uptake is controlled by AMP-activated protein kinase (show PRKAA2 Antibodies), a ubiquitous sensor of energy depletion. [REVIEW]

Mouse (Murine) Solute Carrier Family 6 (Neurotransmitter Transporter, Creatine), Member 8 (SLC6A8) interaction partners

  1. This essential role of calreticulin (show CALR Antibodies) in nucleocytoplasmic communication competency ties its regulatory action with proficiency of cardiac myofibrillogenesis essential for proper cardiac development.

  2. Study provides evidence that chronic stress activates calreticulin (show CALR Antibodies) and might be one of the pathological mechanisms underlying the motor coordination and motor learning dysfunctions seen in social defeat mice.

  3. This study for the first time revealed that increased CRT inhibited Fas (show FAS Antibodies)/FasL (show FASL Antibodies)-mediated neuronal cell apoptosis during the early stage of ischemic stroke, suggesting it to be a potential protector activated soon after ischemia-reperfusion injury

  4. The findings highlight the importance of CALR (show CALR Antibodies) in female reproduction and demonstrate that compromised CALR (show CALR Antibodies) function leads to ovarian insufficiency and female infertility.

  5. Calreticulin (show CALR Antibodies) mediates vascular smooth muscle cell responses to injury through the regulation of collagen deposition and neointima formation.

  6. CALR (show CALR Antibodies) mutants are sufficient to induce thrombocytosis through MPL (show MPL Antibodies) activation.

  7. Thrombopoietin receptor (show MPL Antibodies) activation by myeloproliferative neoplasm associated calreticulin (show CALR Antibodies) mutants.

  8. These studies reveal central roles for ATP and calcium binding as regulators of calreticulin (show CALR Antibodies)-substrate interactions and as key determinants of PLC (show HSPG2 Antibodies) dynamics.

  9. study demonstrates for the first time that LRH-1 (show NR5A2 Antibodies) has a CRT-dependent NES (show NES Antibodies) which is not only required for cytoplasmic trafficking, but also essential for correct protein folding to avoid misfolding-induced aggregation.

  10. Arginylated CRT has a longer half-life than non-arginylated CRT and displays different ubiquitin dependence.

Cow (Bovine) Solute Carrier Family 6 (Neurotransmitter Transporter, Creatine), Member 8 (SLC6A8) interaction partners

  1. Mammalian target of rapamycin (mTOR (show FRAP1 Antibodies)) stimulates the creatine transporter SLC6A8 through mechanisms at least partially shared by the serum and glucocorticoid-inducible kinase SGK1 (show SGK1 Antibodies).

  2. The observations suggest that SGK1 (show SGK1 Antibodies) regulates the creatine transporter SLC6A8 at least partially through phosphorylation and activation of PIKfyve (show PIKFYVE Antibodies).

SLC6A8 Antigen Profile

Antigen Summary

The protein encoded by this gene is a plasma membrane protein whose function is to transport creatine into and out of cells. Defects in this gene can result in X-linked creatine deficiency syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with SLC6A8

  • solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8) antibody
  • solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (slc6a8) antibody
  • calreticulin (CALR) antibody
  • calreticulin (Calr) antibody
  • solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (Slc6a8) antibody
  • solute carrier family 6 (neurotransmitter transporter), member 8 (SLC6A8) antibody
  • solute carrier family 6 (neurotransmitter transporter), member 8 (Slc6a8) antibody
  • AA589632 antibody
  • Calregulin antibody
  • cC1qR antibody
  • CCDS1 antibody
  • CHOT1 antibody
  • CHT1 antibody
  • Creat antibody
  • CRT antibody
  • CRTR antibody
  • CT1 antibody
  • RO antibody
  • SLC6A8 antibody
  • SSA antibody

Protein level used designations for SLC6A8

solute carrier family 6 (neurotransmitter transporter, creatine), member 8 , Sodium- and chloride-dependent creatine transporter 1 , ct1 , sodium- and chloride-dependent creatine transporter 1-like , CRP55 , ERp60 , HACBP , Sicca syndrome antigen A (autoantigen Ro; calreticulin) , calregulin , endoplasmic reticulum resident protein 60 , grp60 , sodium- and chloride-dependent creatine transporter 1 , CT1 , choline transporter , creatine transporter 1 , solute carrier family 6 member 8 , creatine transporter, solute carrier family 6, member 8 , solute carrier family 6, member 8 , creatine transporter SLC6A8

GENE ID SPECIES
473853 Pan troglodytes
567544 Danio rerio
698307 Macaca mulatta
100127575 Xenopus (Silurana) tropicalis
100404520 Callithrix jacchus
100440816 Pongo abelii
100589275 Nomascus leucogenys
811 Homo sapiens
12317 Mus musculus
492242 Canis lupus familiaris
100302506 Sus scrofa
282367 Bos taurus
100009280 Oryctolagus cuniculus
102857 Mus musculus
6535 Homo sapiens
50690 Rattus norvegicus
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