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Browse our SLC6A8 Proteins (SLC6A8)

Full name:
Solute Carrier Family 6 (Neurotransmitter Transporter, Creatine), Member 8 Proteins (SLC6A8)
On www.antibodies-online.com are 5 Solute Carrier Family 6 (Neurotransmitter Transporter, Creatine), Member 8 (SLC6A8) Proteins from 4 different suppliers available. Additionally we are shipping SLC6A8 Antibodies (42) and SLC6A8 Kits (18) and many more products for this protein. A total of 72 SLC6A8 products are currently listed.
Synonyms:
AA589632, Calregulin, cC1qR, CCDS1, CHOT1, CHT1, Creat, CRT, CRTR, CT1, RO, SLC6A8, SSA
list all proteins Gene Name GeneID UniProt
SLC6A8 811 P27797
SLC6A8 12317 P14211
Rat SLC6A8 SLC6A8 50690 P28570

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SLC6A8 Proteins (SLC6A8) by Origin

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More Proteins for SLC6A8 Interaction Partners

Human Solute Carrier Family 6 (Neurotransmitter Transporter, Creatine), Member 8 (SLC6A8) interaction partners

  1. Letter: CALR (show CALR Proteins) mutations are rare in Chinese Budd-Chiari syndrome patients.

  2. CALR (show CALR Proteins) mutated clones are present in bone marrow cells of essential thrombocythemia and primary myelofibrosis patients.

  3. Letter: found no CALR (show CALR Proteins) mutations in patients with first episode of unprovoked venous thromboembolism.

  4. CALR (show CALR Proteins) mutations are associated with BCR (show BCR Proteins)-ABL1 (show ABL1 Proteins) negative Myeloproliferative Disorders.

  5. Flavin reductase (show BLVRB Proteins) and calreticulin (show CALR Proteins) play key roles in the development of pemetrexed-associated resistance in lung adenocarcinoma cells.

  6. Co-existence of JAK2 (show JAK2 Proteins) V617F and CALR (show CALR Proteins) mutations in primary myelofibrosis

  7. Even after CALR (show CALR Proteins) mutation variant stratification, driver mutational status did not impact overall, myelofibrosis-free, thrombosis-free, and leukemia-free survival in essential thrombocythemia.

  8. though CALR (show CALR Proteins) mutations are found at a lower frequency among the Indian patients with PMF (show PRB1 Proteins), they have a distinct molecular profile different from that of other studies worldwide.

  9. mutant CALR (show CALR Proteins) promotes myeloproliferative neoplasm development by activating c-MPL (show MPL Proteins) and its downstream pathway.

  10. Thrombopoietin receptor (show MPL Proteins) activation by myeloproliferative neoplasm associated calreticulin (show CALR Proteins) mutants.

Mouse (Murine) Solute Carrier Family 6 (Neurotransmitter Transporter, Creatine), Member 8 (SLC6A8) interaction partners

  1. This study for the first time revealed that increased CRT inhibited Fas (show FAS Proteins)/FasL (show FASL Proteins)-mediated neuronal cell apoptosis during the early stage of ischemic stroke, suggesting it to be a potential protector activated soon after ischemia-reperfusion injury

  2. The findings highlight the importance of CALR (show CALR Proteins) in female reproduction and demonstrate that compromised CALR (show CALR Proteins) function leads to ovarian insufficiency and female infertility.

  3. Calreticulin (show CALR Proteins) mediates vascular smooth muscle cell responses to injury through the regulation of collagen deposition and neointima formation.

  4. CALR (show CALR Proteins) mutants are sufficient to induce thrombocytosis through MPL (show MPL Proteins) activation.

  5. Thrombopoietin receptor (show MPL Proteins) activation by myeloproliferative neoplasm associated calreticulin (show CALR Proteins) mutants.

  6. These studies reveal central roles for ATP and calcium binding as regulators of calreticulin (show CALR Proteins)-substrate interactions and as key determinants of PLC (show HSPG2 Proteins) dynamics.

  7. study demonstrates for the first time that LRH-1 (show NR5A2 Proteins) has a CRT-dependent NES (show NES Proteins) which is not only required for cytoplasmic trafficking, but also essential for correct protein folding to avoid misfolding-induced aggregation.

  8. Arginylated CRT has a longer half-life than non-arginylated CRT and displays different ubiquitin dependence.

  9. Data suggest that oligomerization of calreticulin (CRT (show CALR Proteins)) may occur under certain pathophysiological conditions (42 degrees C/pH 6.5) and the resultant oligomers may exhibit exaggerated immunostimulating activities.

  10. In calreticulin (show CALR Proteins)-deficient embryonic stem (ES) cells WNT (show WNT2 Proteins) and miR (show MLXIP Proteins)-302 dependent maintenance of the naive ES cell state and the transition to primed pluripotency are lost.

Cow (Bovine) Solute Carrier Family 6 (Neurotransmitter Transporter, Creatine), Member 8 (SLC6A8) interaction partners

  1. Mammalian target of rapamycin (mTOR (show FRAP1 Proteins)) stimulates the creatine transporter SLC6A8 through mechanisms at least partially shared by the serum and glucocorticoid-inducible kinase SGK1 (show SGK1 Proteins).

  2. The observations suggest that SGK1 (show SGK1 Proteins) regulates the creatine transporter SLC6A8 at least partially through phosphorylation and activation of PIKfyve (show PIKFYVE Proteins).

SLC6A8 Protein Profile

Protein Summary

The protein encoded by this gene is a plasma membrane protein whose function is to transport creatine into and out of cells. Defects in this gene can result in X-linked creatine deficiency syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with SLC6A8

  • solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8)
  • solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (slc6a8)
  • calreticulin (CALR)
  • calreticulin (Calr)
  • solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (Slc6a8)
  • solute carrier family 6 (neurotransmitter transporter), member 8 (SLC6A8)
  • solute carrier family 6 (neurotransmitter transporter), member 8 (Slc6a8)
  • AA589632 protein
  • Calregulin protein
  • cC1qR protein
  • CCDS1 protein
  • CHOT1 protein
  • CHT1 protein
  • Creat protein
  • CRT protein
  • CRTR protein
  • CT1 protein
  • RO protein
  • SLC6A8 protein
  • SSA protein

Protein level used designations for SLC6A8

solute carrier family 6 (neurotransmitter transporter, creatine), member 8 , Sodium- and chloride-dependent creatine transporter 1 , ct1 , sodium- and chloride-dependent creatine transporter 1-like , CRP55 , ERp60 , HACBP , Sicca syndrome antigen A (autoantigen Ro; calreticulin) , calregulin , endoplasmic reticulum resident protein 60 , grp60 , sodium- and chloride-dependent creatine transporter 1 , CT1 , choline transporter , creatine transporter 1 , solute carrier family 6 member 8 , creatine transporter, solute carrier family 6, member 8 , solute carrier family 6, member 8 , creatine transporter SLC6A8

GENE ID SPECIES
473853 Pan troglodytes
567544 Danio rerio
698307 Macaca mulatta
100127575 Xenopus (Silurana) tropicalis
100404520 Callithrix jacchus
100440816 Pongo abelii
100589275 Nomascus leucogenys
811 Homo sapiens
12317 Mus musculus
492242 Canis lupus familiaris
100302506 Sus scrofa
282367 Bos taurus
100009280 Oryctolagus cuniculus
102857 Mus musculus
6535 Homo sapiens
50690 Rattus norvegicus
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