You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our T-Box 1 Proteins (TBX1)

Full name:
T-Box 1 Proteins (TBX1)
On are 6 T-Box 1 (TBX1) Proteins from 3 different suppliers available. Additionally we are shipping T-Box 1 Antibodies (71) and T-Box 1 Kits (5) and many more products for this protein. A total of 88 T-Box 1 products are currently listed.
3222402J11Rik, C85531, CAFS, CTHM, DGCR, DGS, DORV, mp:zf637-3-000616, N4WBP3, TBX1, TBX1C, TGA, VCFS, xtbx1, zgc:136724
list all proteins Gene Name GeneID UniProt
TBX1 56722 Q9JLJ0
TBX1 6899 O43435
Rat TBX1 TBX1 360737  

Show all synonyms

T-Box 1 Proteins (TBX1) by Origin

Select your origin of interest

More Proteins for T-Box 1 Interaction Partners

Mouse (Murine) T-Box 1 (TBX1) interaction partners

  1. These results suggest that TBX1 plays a role in maintaining a progenitor state in VEGFR2 (show KDR Proteins)+ cells.

  2. Tbx1 is required upstream of key myogenic genes needed for core mesoderm cell survival and fate, between E9.5 and E10.5, resulting in formation of the branchiomeric muscles.

  3. Tbx1 binds to the miR (show MLXIP Proteins)-96 promoter and represses miR (show MLXIP Proteins)-96 expression.

  4. Loss of Tbx1 in mouse (Tbx1(-/-)) results in skeletal abnormalities similar to those of cleidocranial dysplasia in humans.

  5. Data suggest that atypical inflammatory signaling kinetics may account for the gain of function elicited by the Litaf protein SIMPLE mutation in Charcot-Marie-Tooth Type 1C (CMT1C) patients.

  6. these data suggest that the molecular pathogenesis of ventricular septal defectss in Moz germline mutant mice is due to loss of MOZ-dependant activation of mesodermal Tbx1 and Tbx5 (show TBX5 Proteins) expression.

  7. the present studies establish new insights into molecular aspects of TBX1 binding to DNA.

  8. Prdm1 (show PRDM1 Proteins) functions in the mesoderm of the second heart field, where it interacts genetically with Tbx1, during outflow tract morphogenesis in the mouse embryo.

  9. Tbx1 deletion from the pharyngeal endoderm is sufficient to cause caudal pharyngeal arch segmentation defects by FGF-independent effectors that remain to be identified.

  10. The Tbx1 level is an important determinant of endodermal and mesodermal lineage differentiation during embryonic development.

Human T-Box 1 (TBX1) interaction partners

  1. The results clearly suggest a possible etiologic association between the TBX1 deletion and Tetralogy of Fallot.

  2. TBX1 loss-of-function mutation with enhanced susceptibility to double outlet right ventricle (DORV (show GDF1 Proteins)) and ventricular septal defect (VSD)in humans, which provides novel insight into the molecular mechanism underlying Congenital heart disease (CHD (show CHDH Proteins)).

  3. SNPs in three genes CYP26B1 (show CYP26B1 Proteins) rs2241057, CISD1 (show CISD1 Proteins) rs2251039, rs2590370, and TBX1 rs4819522 were involved in six potential pathways to influence serum prostate-specific antigen (show KLK3 Proteins) levels.

  4. TBX1 T-box domain binds DNA as two distinct monomers.

  5. TBX1 isoform C is the biologically essential variant and that TBX1 mutations are associated with a wide phenotypic spectrum, including most of 22q11.2DS phenotypes.

  6. Findings indicate an association between TBX1 variations and fetal CTD. The results also demonstrate the power of array CGH to further scrutinize the critical gene(s) of del22q11.2 syndrome responsible for heart defects.

  7. Observations suggest that TBX1 loss-of-function mutation may be involved in the pathogenesis of isolated conotrucal heart defects (CTDs)in patients without 22q11.2 deletion.

  8. Results show that TBX1 regulates brain angiogenesis through the DLL4 (show DLL4 Proteins)/Notch1 (show NOTCH1 Proteins)-VEGFR3 (show FLT4 Proteins) regulatory axis.

  9. DNA sequence variants within the TBX1 gene promoter may change TBX1 level, contributing to indirect inguinal hernia development as a rare risk factor

  10. TBX1 can alter TGF-beta/BMP (show TGFb Proteins), an important signaling pathway, through interacting with HOXD10 (show HOXD10 Proteins). Above findings may shed light on the mechanism of TBX1 mutations leading to renal malformations found in patients carrying a 22q11 deletion.

Zebrafish T-Box 1 (TBX1) interaction partners

  1. Tbx1 controls the morphogenesis of pharyngeal pouch epithelia through mesodermal Wnt11r (show WNT11 Proteins) and Fgf8a.

  2. Conservation of Tbx1 function in zebrafish second heart field biology.

  3. Her9 represses neurogenic fate downstream of Tbx1 and retinoic acid signaling in the inner ear.

  4. Tbx1 might play an essential role in the development of pharyngeal neural crest cells in zebrafish. Cardiac performance is impaired by Tbx1 knock down in zebrafish.

  5. Retinoic acid could produce an altered Tbx1 expression pattern in zebrafish embryos.

  6. This newly identified tbx1 expression pattern in cardiac regions other than the cardiac outflow tract offers a new insight into the role of the tbx1 transcription factor in cardiac development.

T-Box 1 (TBX1) Protein Profile

Protein Summary

Probable role in regulating transcription of specific genes. May regulate through NFKB1 the expression of the CCL2/MCP-1 chemokine. May play a role in tumor necrosis factor alpha (TNF- alpha) gene expression.

Alternative names and synonyms associated with T-Box 1 (TBX1)

  • T-box 1 (TBX1)
  • T-box 1 (tbx1)
  • LPS-induced TN factor (Litaf)
  • T-box 1 (Tbx1)
  • 3222402J11Rik protein
  • C85531 protein
  • CAFS protein
  • CTHM protein
  • DGCR protein
  • DGS protein
  • DORV protein
  • mp:zf637-3-000616 protein
  • N4WBP3 protein
  • TBX1 protein
  • TBX1C protein
  • TGA protein
  • VCFS protein
  • xtbx1 protein
  • zgc:136724 protein

Protein level used designations for T-Box 1 Proteins (TBX1)

T-box 1 , T-box protein 1 , T-box transcription factor 1 , T-box transcription factor TBX1 , LITAF-like protein , LPS-induced TNF-alpha factor homolog , Nedd4 WW domain-binding protein 3 , estrogen-enhanced transcript protein , lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog , mEET , T-box 1 transcription factor C , Testis-specific T-box protein , brachyury , testis-specific T-box protein , van gogh , vgo

608214 Canis lupus familiaris
771328 Gallus gallus
789959 Bos taurus
458653 Pan troglodytes
619587 Xenopus (Silurana) tropicalis
56722 Mus musculus
6899 Homo sapiens
360737 Rattus norvegicus
21380 Mus musculus
368206 Danio rerio
Selected quality suppliers for T-Box 1 Proteins (TBX1)
Did you look for something else?