T-Box 1 Protein (TBX1) (Transcript Variant C) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2733303

Product Details

Target: T-Box 1 (TBX1)

Protein Type: Recombinant

Protein Characteristics: Transcript Variant C

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This T-Box 1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human TBX1 (transcript variant C) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: T-Box 1 (TBX1)

Alternative Name: Tbx1 (TBX1 Products)

Synonyms: CAFS Protein, CTHM Protein, DGCR Protein, DGS Protein, DORV Protein, TBX1C Protein, TGA Protein, VCFS Protein, mp:zf637-3-000616 Protein, zgc:136724 Protein, TBX1 Protein, dgs Protein, tga Protein, cafs Protein, cthm Protein, dgcr Protein, dorv Protein, vcfs Protein, tbx1c Protein, xtbx1 Protein, tbx1 Protein, T-box 1 Protein, T-box 1 S homeolog Protein, T-box 1 L homeolog Protein, TBX1 Protein, Tbx1 Protein, tbx1 Protein, tbx1.S Protein, tbx1.L Protein

Background: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98 % amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molecular Weight: 52.5 kDa

NCBI Accession: NP_542378

Pathways: Retinoic Acid Receptor Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation