Browse our DDX6 Proteins (DDX6)

Full name:
DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 Proteins (DDX6)
On are 9 DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6) Proteins from 5 different suppliers available. Additionally we are shipping DDX6 Antibodies (122) and DDX6 Kits (10) and many more products for this protein. A total of 151 DDX6 products are currently listed.
1110001P04Rik, E230023J21Rik, HLR2, me31b, mRCK/P54, P54, p54h, RCK, RGD1564560, si:ch211-147p17.1, Xp54
list all proteins Gene Name GeneID UniProt
DDX6 1656 P26196
DDX6 500988  
DDX6 13209 P54823

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DDX6 Proteins (DDX6) by Origin

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More Proteins for DDX6 Interaction Partners

Human DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6) interaction partners

  1. DDX6 modulates interaction of miR (show MLXIP Proteins)-122 with the 5' untranslated region of hepatitis C virus RNA.

  2. we demonstrate that joint deletion of two short conserved motifs that bind UNR and DDX6 relieves repression of 4E-T-bound mRNA, in part reliant on the 4E-T-DDX6-CNOT1 axis.

  3. miRNAs, AGOs, GW182, the CCR4 (show CCR4 Proteins)-NOT complex, and DDX6/Me31B repress and degrade polyadenylated mRNA targets that are translated via scanning-independent mechanisms in both human and Drosophila melanogaster cells

  4. DDX6 may have a role in radio- and chemoresistance in glioblastoma

  5. Functional analysis of the 11q23.3 glioma susceptibility locus implicates PHLDB1 and DDX6 in glioma susceptibility.

  6. DDX6 repression complexes are required for P-body assembly.

  7. Protein Interactome Analysis of DDX6

  8. Results indicate that progenitor function is maintained by DDX6 complexes through two distinct pathways that include the degradation of differentiation-inducing transcripts and by promoting the translation of self-renewal and proliferation mRNAs.

  9. CNOT1 facilitates recruitment of DDX6 to miRNA-targeted mRNAs, placing DDX6 as a downstream effector in the miRNA silencing pathway.

  10. study discovered multiple susceptibility variants for systemic lupus erythematosus in the 11q23.3 region, including variants in/near PHLDB1 (rs11603023), DDX6 (rs638893) and CXCR5 (show CXCR5 Proteins) (rs10892301)

Xenopus laevis DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6) interaction partners

  1. Xp54nrb (show NONO Proteins) transcripts are expressed throughout early developmental stages, specifically in the neural and sensorial territories and Xp54nrb (show NONO Proteins) could be involved in anterior neural patterning

  2. An oligomerized form of p54 (show ETS1 Proteins) RNA helicase represses mRNA translation.

Mouse (Murine) DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6) interaction partners

  1. Data show that RNA helicase DDX6 colocalizes with ubiquitin-protein ligase (show UBE2K Proteins) TRIM32 (show TRIM32 Proteins) in neural stem cells and neurons and that it increases the activity of microRNA Let-7a.

  2. rck/p54 may play an important role in gametogenesis and early embryogenesis in mammals

  3. rck/p54 protein was ubiquitously expressed in mouse tissues

  4. RCK/ p54 might be a determinant of colorectal cancer proliferation by activating the canonical Wnt (show WNT2 Proteins) pathway

DDX6 Protein Profile

Protein Summary

This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Alternative names and synonyms associated with DDX6

  • DEAD (Asp-Glu-Ala-Asp) box helicase 6 (DDX6)
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 (ddx6)
  • DEAD (Asp-Glu-Ala-Asp) box helicase 6 (ddx6)
  • DEAD (Asp-Glu-Ala-Asp) box helicase 6 (Ddx6)
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 (DDX6)
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 (Ddx6)
  • 1110001P04Rik protein
  • E230023J21Rik protein
  • HLR2 protein
  • me31b protein
  • mRCK/P54 protein
  • P54 protein
  • p54h protein
  • RCK protein
  • RGD1564560 protein
  • si:ch211-147p17.1 protein
  • Xp54 protein

Protein level used designations for DDX6

DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 , DEAD box protein 6 , RNA helicase p54 , probable ATP-dependent RNA helicase ddx6 , ATP-dependent RNA helicase p54 , DEAD box-6 , DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 6 (RNA helicase, 54kD) , oncogene RCK , probable ATP-dependent RNA helicase DDX6 , ATP-dependent RNA helicase ddx6 , xp54 , D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 6 , DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 6 , DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 6 , oncogene RCK homolog

451594 Pan troglodytes
564633 Danio rerio
780039 Xenopus (Silurana) tropicalis
100515499 Sus scrofa
1656 Homo sapiens
399080 Xenopus laevis
419783 Gallus gallus
479414 Canis lupus familiaris
500988 Rattus norvegicus
100190811 Pongo abelii
101103918 Ovis aries
513906 Bos taurus
13209 Mus musculus
100135517 Cavia porcellus
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