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anti-Human CSF1 Antibodies:
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Human Monoclonal CSF1 Primary Antibody for ELISA, WB - ABIN560496
Lawlor, Nazarian, Lacomis, Tempst, Villanueva: Pathway-based biomarker search by high-throughput proteomics profiling of secretomes. in Journal of proteome research 2009
Show all 2 references for ABIN560496
Human Monoclonal CSF1 Primary Antibody for IHC, ELISA - ABIN1724725
Price, Choi, Rosenberg, Stanley: The predominant form of secreted colony stimulating factor-1 is a proteoglycan. in The Journal of biological chemistry 1992
Show all 2 references for ABIN1724725
Human Monoclonal CSF1 Primary Antibody for ELISA, IHC - ABIN4332236
Gerngross, Fischer: Evidence for cFMS signaling in HIV production by brain macrophages and microglia. in Journal of neurovirology 2015
Show all 2 references for ABIN4332236
Human Polyclonal CSF1 Primary Antibody for WB - ABIN2781822
West, Rubin, Miller, Subramanian, Kaygusuz, Montgomery, Zhu, Marinelli, De Luca, Downs-Kelly, Goldblum, Corless, Brown, Gilks, Nielsen, Huntsman, van de Rijn: A landscape effect in tenosynovial giant-cell tumor from activation of CSF1 expression by a translocation in a minority of tumor cells. in Proceedings of the National Academy of Sciences of the United States of America 2006
Human Polyclonal CSF1 Primary Antibody for FACS, IF - ABIN390719
Lee, Kim, Yeon, Choi, Chun, Kwak, Oh: GM-CSF regulates fusion of mononuclear osteoclasts into bone-resorbing osteoclasts by activating the Ras/ERK pathway. in Journal of immunology (Baltimore, Md. : 1950) 2009
the high level of colony-stimulating factor 1 expression during bovine pregnancy in uteroplacental tissues is consistent with its proposed role in placental physiology
results suggest that leukemia inhibitory factor (show LIF Antibodies) and macrophage-colony stimulating factor (show CSF2 Antibodies) are produced in the endometrium and may play different roles in early and mid-pregnancy
These results indicate that BARF1 blockade of CSF-1 signaling is an important immune evasion strategy for efficient acute EBV infection and a significant determinant for virus setpoint during persistent EBV infection.
the complete sequencing of M-CSF (show CSF1R Antibodies) genes, gene organizaztion,splice varaiants, gene expression, and M-CSF (show CSF1R Antibodies) role in the immune system
M-CSF macrophage conversion into foam cells reduces their proinflammatory responses to classical M1-polarizing activation
This can be achieved by either blocking the EGF (show EGF Antibodies) or CSF-1 receptors or supressing the EGF (show EGF Antibodies) or CSF-1 signal.
findings demonstrated that M-CSF binds to IL-34 (show IL34 Antibodies); molecular docking studies predicted the formation of a heteromeric M-CSF/IL-34 (show IL34 Antibodies) cytokine
RGC-32 (show C13orf15 Antibodies) expression on M2-polarized and tumor-associated macrophages is M-CSF-dependent and enhanced by tumor-derived IL-4 (show IL4 Antibodies).
Data show crystal structures of CSF1-CSF1R (show CSF1R Antibodies) ternary complexes, and propose a mechanism for their cooperative action that relies on the adoption by dimeric CSF-1 of an active conformational state and homotypic receptor interactions.
In patients with CLE (show EIF2B5 Antibodies), 100 and 150 mg PD-0360324 (monoclonal antibody against MCSF) every 2 weeks for 3 months suppressed a subset of circulating monocytes.
peripheral nerve injury induced de novo expression of colony-stimulating factor 1 (CSF1) in injured sensory neurons. CSF1 was transported to the spinal cord, where it targeted the microglial CSF1 receptor (CSF1R (show CSF1R Antibodies)).
These findings highlight an essential role for PRKAA1 (show PRKAA1 Antibodies)-mediated autophagy during differentiation of human monocytes.
These findings suggest a high usefulness of M-CSF in diagnosing the serous sub-type of epithelial ovarian cancer and in discriminating between cancer and non-carcinoma lesions
expression and release, from osteoblasts of macrophage colony-stimulating factor (show CSF2 Antibodies) (M-CSF), which is indispensable for osteoclast differentiation, was inhibited by uPAR (show PLAUR Antibodies) loss.
study concludes that Langerhans cells require IL-34 (show IL34 Antibodies) when residing in fully differentiated and anatomically intact skin epidermis, but rely on neutrophil-derived CSF1 during inflamma
Proteomic Analysis Reveals Distinct Metabolic Differences Between Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF (show CSF2 Antibodies)) and Macrophage Colony Stimulating Factor (show CSF2 Antibodies) (M-CSF (show CSF1R Antibodies)) Grown Macrophages Derived from Murine Bone Marrow Cells
Hematopoietic cells can be induced by M-CSF (show CSF1R Antibodies) to dedifferentiate to multipotent stem cells.
M-CSF (show CSF1R Antibodies) promotes macrophagic over granulocytic differentiation by inducing ERK (show EPHB2 Antibodies) activation but also PKCd (show PKCd Antibodies) expression, which in turn, down-regulates Fli-1 (show FLI1 Antibodies) expression and prevents granulocytic differentiation.
Results identify CSF-1-activated macrophages as crucial mediators of detrimental Schwann cell dedifferentiation in Cx32 (show GJB1 Antibodies)-deficient mice
Ceramide production in M-CSF (show CSF1R Antibodies)-deprived macrophages arises from a combination of ASMase (show SMPD1 Antibodies) activity and de novo synthesis.
CSF-1 did not rescue the growth and lung defects associated with hyperoxia in this model; however, an increase in CSF-1R (show CSF1R Antibodies)+ macrophages was not associated with an exacerbation of lung injury.
CSF-1 neutralization led to a relatively uniform reduction in all inflammatory cell populations; GM-CSF (show CSF2 Antibodies) neutralization resulted in the preferential loss among the monocyte/macrophage populations.
The results of this study indicated that the CSF1 overexpression observed in CNS pathologies likely has pleiotropic influences on microglia.
FoxO1 (show FOXO1 Antibodies) is highly expressed in M-CSF (show CSF1R Antibodies)-derived (M2-like) macrophage subsets, and this M2-like macrophages showed a preferential FoxO1 (show FOXO1 Antibodies) enrichment on the IL-10 (show IL10 Antibodies) promoter but not in GM-CSF (show CSF2 Antibodies)-derived (M1-like) macrophages
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants.
macrophage colony-stimulating factor 1
, colony stimulating factor 1 (macrophage)
, macrophage colony-stimulating factor 1-like
, colony-stimulating factor 1