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anti-Mouse (Murine) FGF1 Antibodies:
anti-Human FGF1 Antibodies:
anti-Rat (Rattus) FGF1 Antibodies:
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Human Polyclonal FGF1 Primary Antibody for WB - ABIN966136
Le Beau, Espinosa, Neuman, Stock, Roulston, Larson, Keinanen, Westbrook: Cytogenetic and molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases. in Proceedings of the National Academy of Sciences of the United States of America 1993
Show all 3 Pubmed References
Human Polyclonal FGF1 Primary Antibody for Neut, WB - ABIN223523
Feito, Lozano, Alcaide, Rama?rez-Santilla?n, Arcos, Vallet-Rega?, Portola?s: Immobilization and bioactivity evaluation of FGF-1 and FGF-2 on powdered silicon-doped hydroxyapatite and their scaffolds for bone tissue engineering. in Journal of materials science. Materials in medicine 2011
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Human Monoclonal FGF1 Primary Antibody for IF, IHC (p) - ABIN515608
Matsuo, Fukuzawa, Matsumura: A simple agroinfiltration method for transient gene expression in plant leaf discs. in Journal of bioscience and bioengineering 2016
Human Monoclonal FGF1 Primary Antibody for IF, PLA - ABIN560864
Lee, Kang, Suk, Schwab, Yu, McGeer: Acidic fibroblast growth factor (FGF) potentiates glial-mediated neurotoxicity by activating FGFR2 IIIb protein. in The Journal of biological chemistry 2011
Western Blot analysis revealed a decrease in FGF-1 protein expression after day 40 in the porcine umbilical cord during pregnancy
lncRNA-Map2k4 is the target gene of miR-199a, and its down-regulation promotes miR-199a expression in neurons. miR-199a targeted regulation of FGF1 expression in neurons.
clearly demonstrate the different specificity of FGF12 (show FGF12 Antibodies)-FGFR1c2 and FGF22 (show FGF22 Antibodies)-FGFR1c2 for well defined HS structures and suggest that it is now possible to chemoenzymatically synthesize precise HS polysaccharides that can selectively mediate growth factor signaling
The study supports a pro-adipogenic role for betaKlotho (show KLB Antibodies) in skeletal muscle fibro/adipogenesis and calls for further research on involvement of the FGF-FGFR (show FGFR2 Antibodies)-betaKlotho (show KLB Antibodies) axis in the fibro/adipogenic infiltration associated with functional deterioration of skeletal muscle in aging and muscular dystrophy.
fibroblast growth factor 1 (FGF1) to be synergistically induced by heat shock and wounding.
Data suggest that Fgf1-mediated signaling represents an important signaling cascade related to adipogenesis and visceral adiposity; expression of Fgf1 (fibroblast growth factor 1) and Fgfr1 (fibroblast growth factor receptor 1 (show FGFR1 Antibodies)) is up-regulated in adipose tissue of obese mice (both obese mice due to high-fat diet and obese mice due to genetic deletion of leptin (show LEP Antibodies)).
Study presents a transcript profiling of remyelinated multiple sclerosis lesions and identified FGF1 as a promoter of remyelination
Nucleolin-FGF1 interaction is critical for the intranuclear phosphorylation of FGF1 by PKCdelta and thereby the regulation of nuclear export of FGF1.
parenteral delivery of a single dose of recombinant FGF1 (rFGF1) results in potent, insulin (show INS Antibodies)-dependent lowering of glucose levels in diabetic mice that is dose-dependent but does not lead to hypoglycaemia
Although FGF1 transgenic mice had a normal phenotype with unperturbed kidney structure, they showed a severely inhibited kidney repair after unilateral ischemia/reperfusion. This was manifested by a strong decrease of postischemic kidney size and weight.
RA via RALDH2 (show ALDH1A2 Antibodies) has separable functions in the developing spinal cord to (i) maintain high levels of FGF and Notch (show NOTCH1 Antibodies) signaling and (ii) drive stem cell differentiation, thus restricting both the numbers and the pluripotent character of neural stem cells
FGF1 and FGF7 (show FGF7 Antibodies) may be involved differently in the process of follicle maturation and CL formation, which is strongly dependent on angiogenesis
Transfected FGF1 promotes angiogenic proliferation.
These observations suggest a crucial role for cancer-associated fibroblasts and fibroblast growth factor-1/fibroblast growth factor receptor 4 (show FGFR4 Antibodies) signaling in the progression of ovarian cancer. the expression level of Snail1 (show SNAI1 Antibodies) and MMP3 (show MMP3 Antibodies) was reduced, while the expression level of E-cadherin (show CDH1 Antibodies) increased
Enzyme-linked immunosorbent assay was used to detect the levels of chemokine (C-X-C motif) ligand 12, chemokine (C-X-C motif) ligand 7, hepatocyte growth factor, and fibroblast growth factor 1 in the supernatants of the laryngeal squamous cell carcinoma and control cells.
The results indicate that suramin blocks the interaction between hFGF1 and FGFR2 (show FGFR2 Antibodies) D2.
activation of AurA (show AURKA Antibodies) kinase through FGF1/FGFR (show FGFR2 Antibodies) signaling axis sustains the stem cell characteristics of glioblastoma cells.
Study showed that both aFGF and bFGF (show FGF2 Antibodies) were highly expressed in cervical cancer tissues. In tumors of higher clinical stages, the expression of these factors was further enhanced, suggesting that they play a role in facilitating cervical cancer cell proliferation.
FGF1 may play a role in the pathogenesis of T2 diabetes mellitus.
anti-importin alpha1 antibody treatment suppressed the importin alpha1-FGF1 complex formation and ERK1/2 activation, resulting in decreased cell growth. This study provides novel evidence that functional importin alpha1 is located at the cell surface, where it accelerates the proliferation of cancer cells.
The mutational introduction of a novel Cys (show DNAJC5 Antibodies) residue (Ala66Cys) that forms a stabilizing disulfide bond (i.e., cystine) with one of the extant Cys (show DNAJC5 Antibodies) residues (Cys83) effectively eliminates one Cys (show DNAJC5 Antibodies) while increasing overall stability.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described.
, acidic fgf
, acidic fibroblast growth factor
, fibroblast growth factor 1
, heparin-binding growth factor 1
, fibroblast growth factor 1 (acidic)
, heparin-binding growth factor 1 isoform 1 proprotein
, Heparin-binding growth factor 1
, EDGF II
, acidic eye-derived growth factor II
, endothelial cell growth factor beta and alpha chains
, endothelial growth factor
, fibroblast growth factor, acidic
, beta-endothelial cell growth factor
, endothelial cell growth factor, alpha
, endothelial cell growth factor, beta
, Fibroblast growth factor 1 (heparin binding)
, acidic fibroblast growth factor, aFGF
, alpha-endothelial cell growth factor
, endothelial cell growth factor
, Acidic fibroblast growth factor