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FIG4 Antibodies

(FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4))
The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J. [provided by RefSeq, Jul 2008].
anti-FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4) (Center) antibody anti-FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4) (Center) antibody anti-FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4) (Center) antibody (ABIN2856730)

FIG4 Reactivity: Human ICC, IF, IHC (p), WB Host: Rabbit Polyclonal unconjugated

anti-FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4) (AA 846-874), (C-Term) antibody anti-FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4) (AA 846-874), (C-Term) antibody anti-FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4) (AA 846-874), (C-Term) antibody (ABIN1537627)

FIG4 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB24204 unconjugated

anti-FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4) antibody (ABIN1304637)

FIG4 Reactivity: Mammalian ISt, IHC, WB Host: Mouse Monoclonal N202-7 unconjugated

FIG4 Antibodies by Reactivity

Find FIG4 Antibodies for a variety of species such as anti-Human FIG4, anti-Mouse FIG4, anti-Rat FIG4. The species listed below are among those available. Click on a link to go to the corresponding products.

FIG4 Antibodies by Application

Find FIG4 Antibodies validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

FIG4 Antibodies by Host

Find FIG4 Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

FIG4 Antibodies by Binding Specificity

Find FIG4 Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

FIG4 Antibodies by Clonality

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FIG4 Antibodies by Clone

Find FIG4 Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

FIG4 Antibodies by Conjugate

Find FIG4 Antibodies with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular FIG4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB
Validations
Cat. No. ABIN7181220
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, WB
Validations
Cat. No. ABIN4901542
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application IHC, WB
Validations
Cat. No. ABIN1842119
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN7267203
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application ELISA, ICC, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
Cat. No. ABIN1385590
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application IHC (fro), IHC (p), WB
Validations
Cat. No. ABIN1392763
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF/ICC, IHC (fp), WB
Validations
Cat. No. ABIN2800380
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN1392759
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN1392760
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN1392762
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN1392761
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN1392764
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN1410651
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN1410652
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN1410654
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our FIG4 Antibodies

Vaccari, Carbone, Previtali, Mironova, Alberizzi, Noseda, Rivellini, Bianchi, Del Carro, DAntonio, Lenk, Wrabetz, Giger, Meisler, Bolino: "Loss of Fig4 in both Schwann cells and motor neurons contributes to CMT4J neuropathy." in: Human molecular genetics, Vol. 24, Issue 2, pp. 383-96, (2014) (PubMed).

de Kovel, Meisler, Brilstra, van Berkestijn, van t Slot, van Lieshout, Nijman, OBrien, Hammer, Estacion, Waxman, Dib-Hajj, Koeleman: "Characterization of a de novo SCN8A mutation in a patient with epileptic encephalopathy." in: Epilepsy research, Vol. 108, Issue 9, pp. 1511-8, (2014) (PubMed).

Reifler, Lenk, Li, Groom, Brooks, Wilson, Bowerson, Dirksen, Meisler, Dowling: "Murine Fig4 is dispensable for muscle development but required for muscle function." in: Skeletal muscle, Vol. 3, Issue 1, pp. 21, (2013) (PubMed).

Tahtouh, Elkins, Filippakopoulos, Soundararajan, Burgy, Durieu, Cochet, Schmid, Lo, Delhommel, Oberholzer, Pearl, Carreaux, Bazureau, Knapp, Meijer: "Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B." in: Journal of medicinal chemistry, Vol. 55, Issue 21, pp. 9312-30, (2012) (PubMed).

Zolov, Bridges, Zhang, Lee, Riehle, Verma, Lenk, Converso-Baran, Weide, Albin, Saltiel, Meisler, Russell, Weisman: "In vivo, Pikfyve generates PI(3,5)P2, which serves as both a signaling lipid and the major precursor for PI5P." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 43, pp. 17472-7, (2012) (PubMed).

Lenk, Ferguson, Chow, Jin, Jones, Grant, Zolov, Winters, Giger, Dowling, Weisman, Meisler: "Pathogenic mechanism of the FIG4 mutation responsible for Charcot-Marie-Tooth disease CMT4J." in: PLoS genetics, Vol. 7, Issue 6, pp. e1002104, (2011) (PubMed).

Yan, Guo, Zhang, Bai, Wang, Li: "Trauma does not accelerate neuronal degeneration in Fig4 insufficient mice." in: Journal of the neurological sciences, Vol. 312, Issue 1-2, pp. 102-7, (2011) (PubMed).

Vaccari, Dina, Tronchère, Kaufman, Chicanne, Cerri, Wrabetz, Payrastre, Quattrini, Weisman, Meisler, Bolino: "Genetic interaction between MTMR2 and FIG4 phospholipid phosphatases involved in Charcot-Marie-Tooth neuropathies." in: PLoS genetics, Vol. 7, Issue 10, pp. e1002319, (2011) (PubMed).

Aliases for FIG4 Antibodies

FIG4 phosphoinositide 5-phosphatase (Fig4) Antibodies
FIG4 phosphoinositide 5-phosphatase (FIG4) Antibodies
A530089I17Rik Antibodies
AI326867 Antibodies
ALS11 Antibodies
CMT4J Antibodies
dJ249I4.1 Antibodies
KIAA0274 Antibodies
Kiaa0274 Antibodies
RGD1311375 Antibodies
Sac3 Antibodies
SAC3 Antibodies
YVS Antibodies
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