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Browse our FGF1 Proteins (FGF1)

Full name:
Fibroblast Growth Factor 1 (Acidic) Proteins (FGF1)
On are 113 Fibroblast Growth Factor 1 (Acidic) (FGF1) Proteins from 21 different suppliers available. Additionally we are shipping FGF1 Antibodies (222) and FGF1 Kits (96) and many more products for this protein. A total of 451 FGF1 products are currently listed.
AFGF, Dffrx, ECGF, ECGF-beta, ECGFA, ECGFB, Fam, Fgf-1, FGF-alpha, Fgf1, FGFA, GLIO703, HBGF-1, HBGF1, LOC100221393, zgc:136885
list all proteins Gene Name GeneID UniProt
FGF1 14164 P61148
FGF1 2246 P05230
FGF1 25317 P61149

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FGF1 Proteins (FGF1) by Origin

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Top referenced FGF1 Proteins

  1. Human FGF1 Protein expressed in Escherichia coli (E. coli) - ABIN2001899 : Hebart, Einsele: Diagnosis and treatment of cytomegalovirus infection. in Current opinion in hematology 1999 (PubMed)
    Show all 2 references for ABIN2001899

  2. Mouse (Murine) FGF1 Protein expressed in Escherichia coli (E. coli) - ABIN666797 : Stauber, DiGabriele, Hendrickson: Structural interactions of fibroblast growth factor receptor with its ligands. in Proceedings of the National Academy of Sciences of the United States of America 2000 (PubMed)

More Proteins for FGF1 Interaction Partners

Pig (Porcine) Fibroblast Growth Factor 1 (Acidic) (FGF1) interaction partners

  1. Western Blot analysis revealed a decrease in FGF-1 protein expression after day 40 in the porcine umbilical cord during pregnancy

Mouse (Murine) Fibroblast Growth Factor 1 (Acidic) (FGF1) interaction partners

  1. Data suggest that Fgf1-mediated signaling represents an important signaling cascade related to adipogenesis and visceral adiposity; expression of Fgf1 (fibroblast growth factor 1) and Fgfr1 (fibroblast growth factor receptor 1 (show FGFR1 Proteins)) is up-regulated in adipose tissue of obese mice (both obese mice due to high-fat diet and obese mice due to genetic deletion of leptin (show LEP Proteins)).

  2. Study presents a transcript profiling of remyelinated multiple sclerosis lesions and identified FGF1 as a promoter of remyelination

  3. Nucleolin-FGF1 interaction is critical for the intranuclear phosphorylation of FGF1 by PKCdelta and thereby the regulation of nuclear export of FGF1.

  4. parenteral delivery of a single dose of recombinant FGF1 (rFGF1) results in potent, insulin (show INS Proteins)-dependent lowering of glucose levels in diabetic mice that is dose-dependent but does not lead to hypoglycaemia

  5. Although FGF1 transgenic mice had a normal phenotype with unperturbed kidney structure, they showed a severely inhibited kidney repair after unilateral ischemia/reperfusion. This was manifested by a strong decrease of postischemic kidney size and weight.

  6. RA via RALDH2 (show ALDH1A2 Proteins) has separable functions in the developing spinal cord to (i) maintain high levels of FGF and Notch (show NOTCH1 Proteins) signaling and (ii) drive stem cell differentiation, thus restricting both the numbers and the pluripotent character of neural stem cells

  7. discovery of a phenotype for the FGF1 knockout mouse establishes the PPARgamma (show PPARG Proteins)-FGF1 axis as critical for maintaining metabolic homeostasis and insulin (show INS Proteins) sensitization

  8. The results demonstrate that the FGF1/FGFR1 complex constitutes a signalling module that independently of the receptor tyrosine kinase can convey a signal that initiates a strictly timed and periodic release of endocytosed FGF1 into the cytosol/nucleus.

  9. RFX1 (show RFX1 Proteins) may negatively regulate the self-renewal of GBM-SCs (show TWIST1 Proteins) through modulating FGF-1B and FGF1 expression levels by binding the 18-bp cis (show CISH Proteins)-elements of the F1B promoter.

  10. the neuroprotective effects of FGF1 involve inactivation of GSK3beta

Cow (Bovine) Fibroblast Growth Factor 1 (Acidic) (FGF1) interaction partners

  1. FGF1 and FGF7 (show FGF7 Proteins) may be involved differently in the process of follicle maturation and CL formation, which is strongly dependent on angiogenesis

Human Fibroblast Growth Factor 1 (Acidic) (FGF1) interaction partners

  1. Study showed that both aFGF and bFGF (show FGF2 Proteins) were highly expressed in cervical cancer tissues. In tumors of higher clinical stages, the expression of these factors was further enhanced, suggesting that they play a role in facilitating cervical cancer cell proliferation.

  2. FGF1 may play a role in the pathogenesis of T2 diabetes mellitus.

  3. anti-importin (show KPNA4 Proteins) alpha1 antibody treatment suppressed the importin (show KPNA4 Proteins) alpha1-FGF1 complex formation and ERK1/2 activation, resulting in decreased cell growth. This study provides novel evidence that functional importin (show KPNA4 Proteins) alpha1 is located at the cell surface, where it accelerates the proliferation of cancer cells.

  4. The mutational introduction of a novel Cys (show DNAJC5 Proteins) residue (Ala66Cys) that forms a stabilizing disulfide bond (i.e., cystine) with one of the extant Cys (show DNAJC5 Proteins) residues (Cys83) effectively eliminates one Cys (show DNAJC5 Proteins) while increasing overall stability.

  5. The role of intracellular FGF1 is to protect the cell against stress conditions by providing an additional signal for cell survival, independently of receptor-activated signaling cascades.

  6. Data suggest folding of FGF1 is critical for its nonclassical secretion via permeability of lipid bilayer; mutation of proline135 in C-terminus of FGF1 leads to partial unfolding/decrease in FGF1's ability to permeabilize phosphatidylserine bilayers.

  7. The analysis identified a signaling axis between FGF signaling and the transcription factor Sox1 (show SOX1 Proteins), which is preferentially expressed in stem- and mesenchymal-like breast cancers.

  8. FGF-1 synthesis and secretion by synovial fibroblasts were significantly increased in osteoarthritis.

  9. expression of human FGF1 solely in beta-cells in fgf1(-/-) animals prevented overnutrition induced compensatory beta-cell differentiation.

  10. Results show that stress functionally associates FGF1 with AHNAK2 and both proteins with the cytoskeleton and their co-localization in the vicinity of the cell membrane. AHNAK2 seems to be an important element of the FGF1 export pathway.

FGF1 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described.

Alternative names and synonyms associated with FGF1

  • fibroblast growth factor 1 (acidic) (fgf1)
  • fibroblast growth factor 1 (acidic) (FGF1)
  • fibroblast growth factor 1b (fgf1b)
  • fibroblast growth factor 1 (acidic) (LOC100221393)
  • acidic fibroblast growth factor (AFGF)
  • fibroblast growth factor 1 (Fgf1)
  • fibroblast growth factor 1 (acidic) (Fgf1)
  • AFGF protein
  • Dffrx protein
  • ECGF protein
  • ECGF-beta protein
  • ECGFA protein
  • ECGFB protein
  • Fam protein
  • Fgf-1 protein
  • FGF-alpha protein
  • Fgf1 protein
  • FGFA protein
  • GLIO703 protein
  • HBGF-1 protein
  • HBGF1 protein
  • LOC100221393 protein
  • zgc:136885 protein

Protein level used designations for FGF1

FGF-1 , HBGF-1 , aFGF , acidic fgf , acidic fibroblast growth factor , fibroblast growth factor 1 , heparin-binding growth factor 1 , fibroblast growth factor 1 (acidic) , heparin-binding growth factor 1 isoform 1 proprotein , Heparin-binding growth factor 1 , EDGF II , acidic eye-derived growth factor II , endothelial cell growth factor beta and alpha chains , endothelial growth factor , fibroblast growth factor, acidic , prostatropin , beta-endothelial cell growth factor , endothelial cell growth factor, alpha , endothelial cell growth factor, beta , Fibroblast growth factor 1 (heparin binding) , acidic fibroblast growth factor, aFGF , alpha-endothelial cell growth factor , endothelial cell growth factor , Acidic fibroblast growth factor

444686 Xenopus laevis
462158 Pan troglodytes
705970 Macaca mulatta
100005049 Danio rerio
100033960 Equus caballus
100217324 Xenopus (Silurana) tropicalis
100221393 Taeniopygia guttata
397497 Sus scrofa
14164 Mus musculus
281160 Bos taurus
2246 Homo sapiens
25317 Rattus norvegicus
396094 Gallus gallus
607724 Canis lupus familiaris
780480 Ovis aries
100174103 Pongo abelii
101823630 Mesocricetus auratus
101109353 Ovis aries
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