Browse our FGF2 Proteins (FGF2)

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Fibroblast Growth Factor 2 (Basic) Proteins (FGF2)
On are 184 Fibroblast Growth Factor 2 (Basic) (FGF2) Proteins from 25 different suppliers available. Additionally we are shipping FGF2 Antibodies (357) and FGF2 Kits (90) and many more products for this protein. A total of 642 FGF2 products are currently listed.
list all proteins Gene Name GeneID UniProt
FGF2 14173 P15655
FGF2 54250 P13109
FGF2 2247 P09038

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FGF2 Proteins (FGF2) by Origin

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Top referenced FGF2 Proteins

  1. Human FGF2 Protein expressed in Escherichia coli (E. coli) - ABIN2667407 : Cronauer, Schulz, Seifert, Ackermann, Burchardt: Fibroblast growth factors and their receptors in urological cancers: basic research and clinical implications. in European urology 2003 (PubMed)
    Show all 5 references for 2667407

  2. Mouse (Murine) FGF2 Protein expressed in Escherichia coli (E. coli) - ABIN2667409 : Chiou, Xu, Longaker: Mitogenic and chondrogenic effects of fibroblast growth factor-2 in adipose-derived mesenchymal cells. in Biochemical and biophysical research communications 2006 (PubMed)
    Show all 5 references for 2667409

  3. Human FGF2 Protein expressed in Escherichia coli (E. coli) - ABIN2001904 : Wied?ocha, Falnes, Madshus, Sandvig, Olsnes: Dual mode of signal transduction by externally added acidic fibroblast growth factor. in Cell 1994 (PubMed)
    Show all 5 references for 2001904

  4. Mouse (Murine) FGF2 Protein expressed in Escherichia coli (E. coli) - ABIN2007208 : Orpana, Salven: Angiogenic and lymphangiogenic molecules in hematological malignancies. in Leukemia & lymphoma 2002 (PubMed)
    Show all 4 references for 2007208

  5. Human FGF2 Protein expressed in Escherichia coli (E. coli) - ABIN2721053 : Li, Zuo, Jing, Ma, Wang, Liu, Zhu, Du, Xiong, Du, Xu, Xiao, Wang, Chai, Zhao, Deng: Small-Molecule-Driven Direct Reprogramming of Mouse Fibroblasts into Functional Neurons. in Cell stem cell 2015 (PubMed)
    Show all 3 references for 2721053

  6. Human FGF2 Protein expressed in Escherichia coli (E. coli) - ABIN413246 : Matsukura, Muneta, Tsuji, Miyatake, Yamada, Abula, Koga, Tomita, Sekiya: Mouse synovial mesenchymal stem cells increase in yield with knee inflammation. in Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2014 (PubMed)

More Proteins for FGF2 Interaction Partners

Mouse (Murine) Fibroblast Growth Factor 2 (Basic) (FGF2) interaction partners

  1. data suggest that FGF2 levels are critically related to anxiety behavior and hypothalamic pituitary- adrenal axis activity, likely through modulation of hippocampal glucocorticoid receptor (show NR3C1 Proteins) expression, an effect that is likely receptor mediated, albeit not by FGFR1 (show FGFR1 Proteins), FGFR2 (show FGFR2 Proteins), and FGFR3 (show FGFR3 Proteins).

  2. The differentiation of ERF-overexpressing trophoblast stem cell lines also suggests that ERF may have an FGF2-independent effect during the commitment towards syncytiotrophoblasts.

  3. Novel VF-Trap fusion protein on blockage of VEGF (show VEGFA Proteins) and FGF-2 activity to prevent angiogenesis.

  4. FGF2 is an extracellular inducer of COUP-TFII (show NR2F2 Proteins) expression and may suppress the osteogenic potential of mesenchymal cells by inducing COUP-TFII (show NR2F2 Proteins) expression prior to the onset of osteogenic differentiation

  5. clearly demonstrate the different specificity of FGF12 (show FGF12 Proteins)-FGFR1c2 and FGF22 (show FGF22 Proteins)-FGFR1c2 for well defined HS structures and suggest that it is now possible to chemoenzymatically synthesize precise HS polysaccharides that can selectively mediate growth factor signaling

  6. These results support that controlling the aberrant expression of TGF-beta1 (show TGFB1 Proteins) and FGF-2 via inhibition of Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling could serve as a potential therapeutic strategy for pulmonary fibrosis.

  7. (125)I-bFGF mAb inhibits growth of experimental hepatocellular carcinomas.

  8. In vivo, GSPP treatment (200 mg/kg/d) not only inhibited the growth of colon carcinoma, but also inhibited the tumor lymphangiogenesis. Conclusion. GSPP possesses the antitumor ability by inhibiting bFGF-inducing lymphangiogenesis in vitro and in vivo, which may further inhibit tumor lymphatic metastasis.

  9. The present study indicates that a broad array of genes associated with functions of the cytoskeleton is significantly dysregulated in the MSC (show MSC Proteins) cortex of FGF-2 knockout mice

  10. SCN2B (show SCN2B Proteins) could play an important role in the aging-related cognitive deterioration, which is associated with the regulations of COX5A (show COX5A Proteins) and FGF-2.

Zebrafish Fibroblast Growth Factor 2 (Basic) (FGF2) interaction partners

  1. Results uncover a novel Sdc2 (show SDC2 Proteins)-Tbx16-Fgf2 pathway that regulates epithelial cell morphogenesis.

Cow (Bovine) Fibroblast Growth Factor 2 (Basic) (FGF2) interaction partners

  1. Taken together, Staphylococcus aureus induces TGF-beta1 (show TGFB1 Proteins) and bFGF expression through the activation of AP-1 (show JUN Proteins) and NF-kappaB (show NFKB1 Proteins) in bovine mammary gland fibroblasts.

  2. Data suggest THBS1 (thrombospondin-1 (show THBS1 Proteins)) expression predominates in luteal endothelial cells; THBS2 (show THBS2 Proteins) expression predominates in luteinized granulosa cells. Luteinizing signals down-regulate expression of THBS1 (show THBS1 Proteins)/THBS2 (show THBS2 Proteins) but up-regulate expression of FGF2.

  3. Mixed populations of luteal cells were treated with SU1498 (VEGF receptor 2 inhibitor) or SU5402 (FGF receptor 1 inhibitor) or control on days 0-3, 3-6 or 6-9 to determine the role of FGF2 and VEGFA (show VEGFA Proteins) during these specific windows.

  4. FGF2 was crucial for luteal endothelial network formation.

  5. Associations between reproduction and milk traits, and polymorphisms at the STAT5A (show STAT5A Proteins) and FGF2 gene loci, were found with STAT5A (show STAT5A Proteins) polymorphism for age at first calving (suggestive effect; P =0.077) and lactation milk yield (significant effect; P<0.05).

  6. FGF2 and FGF10 (show FGF10 Proteins) regulate migratory activity of ovine trophoblast cells through MAPK (show MAPK1 Proteins)-dependent pathways.

  7. investigation of signaling mechanisms used by FGF2 to regulate interferon-tau (IFNT) production in trophoblasts: several lines of evidence suggest that FGF2 regulates IFNT production in trophoblasts by acting through protein kinase C-delta (show PKCd Proteins)

  8. Alterations in the expression of VEGF-A (show VEGFA Proteins) and bFGF systems suggest that angiogenic factors are involved in abnormal placental development in cloned gestations, contributing to impaired fetal development and poor survival rates.

  9. bFGF is oxidized by lysyl oxidase (show LOX Proteins)

  10. vascular endothelial growth factor indirectly stimulates smooth muscle cell proliferation and migration through the modulation of basic fibroblast growth factor and transforming growth factor beta(1 (show TGFB1 Proteins)) released by endothelial cells

Human Fibroblast Growth Factor 2 (Basic) (FGF2) interaction partners

  1. VASH2 (show VASH2 Proteins) expression is positively correlated with FGF2 expression and promotes angiogenesis in human luminal breast cancer by transcriptional activation of fibroblast growth factor 2 through non-paracrine mechanisms.

  2. our results indicate that different concentrations of bFGF and EGF (show EGF Proteins) supplemented during propagation of neural rosettes are involved in altering the identity of the resultant neural cells.

  3. Novel VF-Trap fusion protein on blockage of VEGF (show VEGFA Proteins) and FGF-2 activity to prevent angiogenesis.

  4. NCAM (show NCAM1 Proteins)- and FGF-2-mediated FGFR1 (show FGFR1 Proteins) signaling in the tumor microenvironment regulates the survival and migration of esophageal squamous carcinoma cells.

  5. Blood BFGF was significantly higher in chronic hepatitis C patients with liver fibrosis compared to those without fibrosis.

  6. PTTG (show PTTG1 Proteins)-mediated FGF2 upregulation is associated with more aggressive tumor features in patients with acromegaly. Also, locally produced estrogen through aromatization might have a role in this phenomenon.

  7. The study provides evidence that small interfering RNA-mediated silencing of basic fibroblast growth factor gene inhibits the proliferation, migration, and invasion of human pituitary adenoma cells

  8. Data suggest that FGF2 (fibroblast growth factor 2) is expressed in 85% of cases with uterine leiomyomas, 88% of cases with uterine smooth muscle tumors of uncertain malignant potential (STUMP), and 57% of cases with uterine leiomyosarcoma; survival is significantly shortened in patients with FGF2-positive compared to FGF-2 negative tumors.

  9. bFGF C754G gene polymorphism was associated with the susceptibility and prognosis of malignant melanoma.

  10. these findings suggest that IGFBP-3 (show IGFBP3 Proteins) suppresses transcription of EGR1 (show EGR1 Proteins) and its target genes bFGF and PDGF (show PDGFA Proteins) through inhibiting IGF-1 (show IGF1 Proteins)-dependent ERK (show EPHB2 Proteins) and AKT (show AKT1 Proteins) activation.

Rabbit Fibroblast Growth Factor 2 (Basic) (FGF2) interaction partners

  1. Continuous passive motion can promote b-FGF expression to enhance type III collagen (show COL3A1 Proteins) synthesis at the tendon-bone interface in early stage of tendon-bone repair following acute rupture of supraspinatus tendon in rabbits.

Pig (Porcine) Fibroblast Growth Factor 2 (Basic) (FGF2) interaction partners

  1. Fibroblast growth factor-2 promotes in vitro heart valve interstitial cell repair through the Akt1 (show AKT1 Proteins) pathway.

  2. The overlapping relationships of 3'UTR ends between NUDT6 (show NUDT6 Proteins) and FGF-2 genes, were analyzed.

  3. FGF2 in porcine ovary may be important for the growth of more follicles due to the localisation and concentration difference between stroma and follicle tissue.

  4. By inducing the release of an endothelial elastase, shear stress induces an integrin-dependent release of FGF-2 from endothelial cells.

  5. qPCR analysis demonstrated an increase in FGF-2 mRNA levels beginning on day 75 and on day 114 of pregnancy.

  6. FGF2 activates FGFR (show FGFR2 Proteins) which then represses the fibroblast activation of valvular interstitial cells.

  7. FGF2 effectively blocks transforming growth factor-beta1 (TGF-beta1 (show TGFB1 Proteins))-mediated myofibroblast activation

  8. upregulation of TGFalpha or FGF2 expression is not a pre-requisite for enhanced testicular growth and increased Sertoli cell proliferation that occurs subsequent to hemicastration in the neonatal boar

Xenopus laevis Fibroblast Growth Factor 2 (Basic) (FGF2) interaction partners

  1. These results suggest that bFGF activation of neuronal FGFR1 (show FGFR1 Proteins) generates filopodial processes in neurons that promote nerve-muscle interaction and facilitate NMJ establishment.

FGF2 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.

Alternative names and synonyms associated with FGF2

  • fibroblast growth factor 2 (Fgf2)
  • fibroblast growth factor 2 (fgf2)
  • fibroblast growth factor 2 (basic) (FGF2)
  • fibroblast growth factor 2 (basic) (Fgf2)
  • fibroblast growth factor 2 (basic) (fgf2)
  • BFGF protein
  • FGF-2 protein
  • FGFB protein
  • HBGF-2 protein

Protein level used designations for FGF2

HBGF-2 , basic fibroblast growth factor , heparin-binding growth factor 2 , BFGF , fibroblast growth factor 2 , basic fibroblast growth factor bFGF , prostatropin , Basic fibroblast growth factor , Heparin-binding growth factor 2

14173 Mus musculus
54250 Rattus norvegicus
404231 Danio rerio
281161 Bos taurus
2247 Homo sapiens
396413 Gallus gallus
100009068 Oryctolagus cuniculus
100721182 Cavia porcellus
397643 Sus scrofa
403857 Canis lupus familiaris
443306 Ovis aries
641462 Pan troglodytes
100101279 Xenopus laevis
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