FGF2 Protein (AA 135-288, Isoform 1)
Quick Overview for FGF2 Protein (AA 135-288, Isoform 1) (ABIN2017855)
Target
See all FGF2 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
-
-
Protein Characteristics
- Isoform 1, AA 135-288
-
Characteristics
- ED50 < 0.25 ng/mL, measured by the cell proliferation assay using 3T3 cells, corresponding to a specific activity of > 4 x 10^6 units/mg.
-
Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!Your project requires further customization? Contact us and discover our custom protein solutions
-
Fibroblast Growth Factor 2 (Basic) (FGF2) (full length) (Active) protein
FGF2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE CC Active
Fibroblast Growth Factor 2 (Basic) (FGF2) (AA 143-288) (Active) protein (AVI tag,His tag,Biotin)FGF2 Origin: Human Host: Escherichia coli (E. coli) Recombinant >90 % as determined by SDS-PAGE. Active
Fibroblast Growth Factor 2 (Basic) (FGF2) (Active) protein (His tag)FGF2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE Active
Fibroblast Growth Factor 2 (Basic) (FGF2) (AA 189-288) protein (GST tag)FGF2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Fibroblast Growth Factor 2 (Basic) (FGF2) (AA 9-154) (Active) protein (His tag)FGF2 Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Fibroblast Growth Factor 2 (Basic) (FGF2) (AA 143-288) (Active) protein (His tag)FGF2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Fibroblast Growth Factor 2 (Basic) (FGF2) (AA 10-154) (Active) protein (His tag)FGF2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Fibroblast Growth Factor 2 (Basic) (FGF2) proteinFGF2 Origin: Human Host: Escherichia coli (E. coli) Recombinant 97,00% SDS
Fibroblast Growth Factor 2 (Basic) (FGF2) proteinFGF2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant 95,00% SDS
Fibroblast Growth Factor 2 (Basic) (FGF2) proteinFGF2 Origin: Rat Host: Escherichia coli (E. coli) Recombinant 95,00% SDS
-
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Reconstituted in ddH2O at 100 μg/mL.
-
Buffer
- Lyophilized after extensive dialysis against PBS.
-
Storage
- -80 °C
-
Storage Comment
- Lyophilized recombinant human Fibroblast Growth Factor-basic (rhFGF-basic) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhFGF-basic remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
-
Expiry Date
- 6 months
-
-
- FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
-
Alternative Name
- Fibroblast Growth Factor-Basic (FGF-Basic)
-
Background
-
Fibroblast Growth Factor-basic (FGF-basic), also known as FGF-2, is a pleiotropic cytokine and one of the prototypic members of the heparin-binding FGF family. Like other FGF family members, bFGF has the beta trefoil structure. In vivo, bFGF is produced by a variety of cells, including cardiomycotes, fibroblasts, and vascular cells. bFGF regulates a variety of processes including cell proliferation, differentiation, survival, adhesion, motility, apoptosis, limb formation and wound healing. bFGF can be tumorigenic due to its role in angiogenesis and blood vessel remodeling. The angiogenic effects of bFGF can produce beneficial cardioprotection during acute heart injury.Recombinant human Fibroblast Growth Factor-basic (rhFGF-basic) produced in E. coli is a single non-glycosylated polypeptide chain containing 154 amino acids. A fully biologically active molecule, rhFGF-basic has a molecular mass of 17.1 kDa analyzed by reducing SDS-PAGE.
Synonyms: Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin -
Molecular Weight
- 17.1 kDa, observed by reducing SDS-PAGE.
-
UniProt
- P09038
-
Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins
Target
-
