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Human FGF7 Protein expressed in Escherichia coli (E. coli) - ABIN2667546
Richardson, Bazzi, Fantauzzo, Waters, Crawford, Hynd, Christiano, Jahoda: KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin. in Development (Cambridge, England) 2009
Show all 5 references for ABIN2667546
Human FGF7 Protein expressed in Escherichia coli (E. coli) - ABIN2452198
Aaronson, Bottaro, Miki, Ron, Finch, Fleming, Ahn, Taylor, Rubin: Keratinocyte growth factor. A fibroblast growth factor family member with unusual target cell specificity. in Annals of the New York Academy of Sciences 1992
Show all 2 references for ABIN2452198
Suppression of miR (show MLXIP Proteins)-219-5p may benefit the liver regeneration and prevent cirrhosis through increasing KGF.
This study evaluated the expression of FGF7, AhR (show AHR Proteins), and CYP1A1 (show CYP1A1 Proteins) in colorectal cancer cells and revealed a new mechanism by which KGF promotes cell proliferation through the AhR (show AHR Proteins)-cyclin D1 (show CCND1 Proteins) pathway in colon cancer cells.
KGF expression induced epithelial cell proliferation, reaching a peak level at day 4 and then decreased later, while in the long-term model, KGF expression in the EAC (show CYLD Proteins) led to middle ear cholesteatoma formation
In the current study, conditioned media and chemically defined media with recombinant human keratinocyte growth factor (KGF) could induce hUC (show ELAVL3 Proteins)-MSC (show MSC Proteins) differentiation into sweat gland-like cells (SGCs).
Coexpression of KGF and MMP-9 (show MMP9 Proteins) in gastric cancer could be a useful prognostic factor, and MMP-9 (show MMP9 Proteins) might also serve as a novel target for both prognostic prediction and therapeutics.
FGF7 over expression is associated with advanced clinical features in patients with upper tract and bladder urothelial carcinoma
Data indicate the key roles played, on the melanosome transfer in normal skin, by KGF/FGF7 released by dermal fibroblasts and by its receptor KGFR (show FGFR2 Proteins)/FGFR2b expressed and activated on the epidermal keratinocytes.
First evidence of a role of FGF7 in the regulation of sequential steps of the autophagic process and strengthen the hypothesis of a direct interplay between autophagy and differentiation.
An SNP in FGF7 is associated with an increased risk of chronic obstructive pulmonary disease.
These findings indicate that topically delivered KGF-1 DNA plasmid can increase epithelial thickness and strength, demonstrating the potential of this approach to restore compromised skin.
Subset of KGF-expressing respiratory epithelial cells may participate in a hitherto undescribed autocrine loop for stimulating KGF production in response to injury.
analysis of regulation of endometrial fibroblast growth factor 7 (FGF-7) and its receptor FGFR2IIIb (show FGFR2 Proteins)
This study investigates the relationships between progesterone, estradiol, and their receptors and the expression of FGF7 in the pig uterus in vivo.
BMP4 (show BMP4 Proteins) promotes activation of FGF7 and FGF10 (show FGF10 Proteins) signaling, leading to an increase in proliferative basal cell population in developing skin.
we examine how the two presynaptic organizers FGF22 (show FGF22 Proteins) and FGF7 are transported to the appropriate locations so that they act as synapse-type-specific organizing molecules.
Exendin-4 increased fibroblast growth factor 7 (Fgf7) expression in colonic polyps of Apc (show APC Proteins)(Min/+) mice.
Our observations also point towards PI3K acting as a morphogenic switch for FGF7 signalling.
Reverse transcriptase polymerase chain reaction studies showed that three members, Tgfa, Hbegf,and Nrg1 of the EGF family were expressed in the epithelium cultured with FGF7 + LPA as well as in the epithelium freshly isolated from the rudiments.
IL-19 (show IL19 Proteins) is important for cutaneous wound healing because it upregulates KGF expression.
FGF7 is downregulated in MED1 (show MBD4 Proteins)-deficient mesenchymal cells. FGF7 produced by mesenchymal stromal cells is a novel hematopoietic niche molecule.
KGF pretreatment could improve radiation-induced intestinal injury including the epithelial structure and function in a mouse model, as shown by Zo-1 (show TJP1 Proteins) protein and Claudin-1 (show CLDN1 Proteins).
KGF could up-regulate IL-7 (show IL7 Proteins) expression through the STAT1 (show STAT1 Proteins)/IRF-1 (show IRF1 Proteins), IRF-2 (show IRF2 Proteins) signaling pathway, which is a new insight in potential effects of KGF on the intestinal mucosal immune system.
FGF1 (show FGF1 Proteins) and FGF7 may be involved differently in the process of follicle maturation and CL formation, which is strongly dependent on angiogenesis
FGF7 may be an important regulator for oocyte growth and its action is mediated via the KIT/KITLG (show KITLG Proteins) signaling pathway.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.
Putative keratinocyte growth factor-like protein 2
, fibroblast growth factor 7 (keratinocyte growth factor)
, keratinocyte growth factor
, Keratinocyte growth factor
, heparin-binding growth factor 7
, fibroblast growth factor-7