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FGF7 Protein (AA 32-194)

FGF7 Origin: Human Host: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Catalog No. ABIN2018177
  • Target See all FGF7 Proteins
    FGF7 (Fibroblast Growth Factor 7 (FGF7))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 32-194
    Origin
    • 19
    • 8
    • 4
    • 3
    • 1
    • 1
    • 1
    Human
    Source
    • 19
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    CHO Cells
    Characteristics
    ED50 < 1 ng /mL, measured in a proliferation assay using 4MBr5 cells.
    Purity
    > 95 % as analyzed by SDS-PAGE and HPLC.
    Endotoxin Level
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product FGF7 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Storage
    -80 °C
    Storage Comment
    Lyophilized recombinant human Keratinocyte Growth Factor(rhKGF) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Keratinocyte Growth Factor should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    Expiry Date
    6 months
  • Target
    FGF7 (Fibroblast Growth Factor 7 (FGF7))
    Alternative Name
    Keratinocyte Growth Factor (KGF) (FGF7 Products)
    Synonyms
    HBGF-7 Protein, KGF Protein, Kgf Protein, kgf Protein, FGF-7 Protein, fgf7 Protein, fibroblast growth factor 7 Protein, fibroblast growth factor 7 L homeolog Protein, FGF7 Protein, Fgf7 Protein, fgf7 Protein, fgf7.L Protein
    Background
    Keratinocyte Growth Factor (KGF), also known as FGF-7 and HBGF-7, is a mitogen factor belonging to the heparin-binding growth factor family. It is expressed mainly by epithelial cells. KGF binds to fibroblast growth factor receptor 2b (FGFR2b) to form a dimeric complex and initiate downstream signals. KGF plays an important role in embryonic development, cell proliferation and differentiation. It has also been reported to function in kidney and lung development, angiogenesis, wound healing and tumor invasion.
    Synonyms: Keratinocyte Growth Factor, Fibroblast Growth Factor-7, HBGF-7
    Molecular Weight
    16-18 kDa, observed by reducing SDS-PAGE.
    UniProt
    P21781
    Pathways
    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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