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Browse our anti-FLT3 (FLT3) Antibodies

Full name:
anti-Fms-Related tyrosine Kinase 3 Antibodies (FLT3)
On are 325 Fms-Related tyrosine Kinase 3 (FLT3) Antibodies from 32 different suppliers available. Additionally we are shipping FLT3 Kits (32) and FLT3 Proteins (24) and many more products for this protein. A total of 391 FLT3 products are currently listed.
B230315G04, CD135, FLK-2, FLK2, Flt-3, FLT3, Ly72, STK1, wmfl
list all antibodies Gene Name GeneID UniProt
FLT3 14255 Q00342
FLT3 2322 P36888
FLT3 140635  

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Most Popular Reactivities for anti-FLT3 (FLT3) Antibodies

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anti-Mouse (Murine) FLT3 Antibodies:

anti-Human FLT3 Antibodies:

anti-Rat (Rattus) FLT3 Antibodies:

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Top referenced anti-FLT3 Antibodies

  1. Human Polyclonal FLT3 Primary Antibody for EIA, IHC (p) - ABIN359868 : Minami, Yamamoto, Kiyoi, Ueda, Saito, Naoe: Different antiapoptotic pathways between wild-type and mutated FLT3: insights into therapeutic targets in leukemia. in Blood 2003 (PubMed)
    Show all 5 references for ABIN359868

  2. Human Polyclonal FLT3 Primary Antibody for EIA, IHC (p) - ABIN359869 : Seidlits, Reza, Briand, Sereno: Voluntary spatial attention has different effects on voluntary and reflexive saccades. in TheScientificWorldJournal 2003 (PubMed)
    Show all 5 references for ABIN359869

  3. Human Polyclonal FLT3 Primary Antibody for IHC (p), WB - ABIN391982 : Zwaan, Meshinchi, Radich, Veerman, Huismans, Munske, Podleschny, Hählen, Pieters, Zimmermann, Reinhardt, Harbott, Creutzig, Kaspers, Griesinger: FLT3 internal tandem duplication in 234 children with acute myeloid leukemia: prognostic significance and relation to cellular drug resistance. in Blood 2003 (PubMed)
    Show all 4 references for ABIN391982

  4. Human Polyclonal FLT3 Primary Antibody for FACS, IHC (p) - ABIN391981 : Sitnicka, Buza-Vidas, Larsson, Nygren, Liuba, Jacobsen et al.: Human CD34+ hematopoietic stem cells capable of multilineage engrafting NOD/SCID mice express flt3: distinct flt3 and c-kit expression and response patterns on mouse and candidate human hematopoietic ... in Blood 2003 (PubMed)
    Show all 4 references for ABIN391981

  5. Human Polyclonal FLT3 Primary Antibody for IF, WB - ABIN401556 : Sekine, Kataoka, Fukuyama, Adachi, Davydova, Yamamoto, Kobayashi, Fujihashi, Suzuki, Curiel, Shizukuishi, McGhee, Fujihashi: A novel adenovirus expressing Flt3 ligand enhances mucosal immunity by inducing mature nasopharyngeal-associated lymphoreticular tissue dendritic cell migration. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
    Show all 3 references for ABIN401556

  6. Human Polyclonal FLT3 Primary Antibody for EIA, IF - ABIN1449983 : Takahashi: Downstream molecular pathways of FLT3 in the pathogenesis of acute myeloid leukemia: biology and therapeutic implications. in Journal of hematology & oncology 2011 (PubMed)
    Show all 3 references for ABIN1449983

  7. Human Polyclonal FLT3 Primary Antibody for ELISA, WB - ABIN1532338 : Rosnet, Schiff, Pébusque, Marchetto, Tonnelle, Toiron, Birg, Birnbaum: Human FLT3/FLK2 gene: cDNA cloning and expression in hematopoietic cells. in Blood 1993 (PubMed)
    Show all 2 references for ABIN1532338

  8. Human Polyclonal FLT3 Primary Antibody for IHC, ELISA - ABIN1532045 : Rosnet, Matteï, Marchetto, Birnbaum: Isolation and chromosomal localization of a novel FMS-like tyrosine kinase gene. in Genomics 1991 (PubMed)
    Show all 2 references for ABIN1532045

  9. Human Polyclonal FLT3 Primary Antibody for ELISA, WB - ABIN1531319 : Greenman, Stephens, Smith, Dalgliesh, Hunter, Bignell, Davies, Teague, Butler, Stevens, Edkins, OMeara, Vastrik, Schmidt, Avis, Barthorpe, Bhamra, Buck, Choudhury, Clements, Cole, Dicks, Forbes, Gray et al.: Patterns of somatic mutation in human cancer genomes. ... in Nature 2007 (PubMed)
    Show all 2 references for ABIN1531319

More Antibodies against FLT3 Interaction Partners

Mouse (Murine) Fms-Related tyrosine Kinase 3 (FLT3) interaction partners

  1. increased number of osteoclasts in Flt3L (show FLT3LG Antibodies)(-/-) mice may be a consequence of insufficient expression of interferon regulatory factor 8 (show IRF8 Antibodies)

  2. FLT3-tandem duplication mutation directly affects dendritic cell development, indirectly modulating T cell homeostasis and supporting T reg (show KCNH2 Antibodies) cell expansion.

  3. MYB (show MYB Antibodies) and C/EBPalpha (show CEBPA Antibodies) activities are inter-dependent in controlling Flt3 expression to influence lineage commitment of multipotential progenitors.

  4. functional synergy between Flt3 and IL-4R signaling is critical for Stat (show STAT1 Antibodies)-mediated regulation of sterile gamma1 germ-line transcripts and CSR (show SCARA3 Antibodies) to IgG1

  5. STAT5 (show STAT5A Antibodies) activation by FLT3-ITD protects cells treated with the PI3K/Akt (show AKT1 Antibodies) pathway inhibitors from apoptosis by maintaining Mcl-1 (show MCL1 Antibodies) expression through the mTORC1/4EBP1 (show EIF4EBP1 Antibodies)/eIF4E (show EIF4E Antibodies) pathway.

  6. LAMTOR2 (show LAMTOR2 Antibodies) has a role in regulating dendritic cell homeostasis through FLT3-dependent mTOR (show FRAP1 Antibodies) signalling

  7. The Ras-PI3Kgamma (show PIK3CG Antibodies)-Akt (show AKT1 Antibodies)-mTOR (show FRAP1 Antibodies) signaling axis acts downstream of FLT3L (show FLT3LG Antibodies) signaling and is required for development of lung CD103 (show ITGAE Antibodies)(+)and CD11b (show ITGAM Antibodies)(+) dendritic cells. This signaling network regulating tissue-specific DC development is mediated by FLT3.

  8. These results reveal a leukemic pathway involving FAK (show PTK2 Antibodies)/Tiam1 (show TIAM1 Antibodies)/Rac1/PAK1 (show PAK1 Antibodies) and demonstrate an essential role for these signaling molecules in regulating the nuclear translocation of Stat5 (show STAT5A Antibodies) in leukemogenesis.

  9. Accumulation of FLT3(+) CD11c (show ITGAX Antibodies) (+) dendritic cells in psoriatic lesions and the anti-psoriatic effect of a selective FLT3 inhibitor

  10. Hes1 suppresses acute myeloid leukemia (show BCL11A Antibodies) development through FLT3 repression.

Human Fms-Related tyrosine Kinase 3 (FLT3) interaction partners

  1. BTK (show BTK Antibodies) RNA interference inhibits proliferation of FLT3-ITD acute myeloid leukemia (show BCL11A Antibodies) cells.

  2. Identify CDC25A (show CDC25A Antibodies) as an early cell cycle transducer of FLT3-ITD oncogenic signaling, and as a promising target to inhibit proliferation and re-induce differentiation of FLT3-ITD acute myeloid leukemia (show BCL11A Antibodies) cells.

  3. Molecular docking studies suggest the involvement of Leu616, Asp698, Cys694 and Cys828 residues in binding of G-11 to FLT3. The ability of G-11 to cause selective cytotoxicity and induce differentiation in cancer cells could be clinically relevant

  4. Mutations in FLT3 internal tandem duplication is associated with Acute Myeloid Leukemia (show BCL11A Antibodies).

  5. Retroviral expression of FLT3-N676K in myeloid 32D cells induced AML (show RUNX1 Antibodies) in syngeneic C3H/HeJ mice. 3 of 14 C57BL/6J mice transplanted with FLT3-N676K-transduced primary hematopoietic progenitor cells developed acute leukemia.

  6. Nox4 (show NOX4 Antibodies) knockout (Nox4 (show NOX4 Antibodies)(-/-)) murine hematopoietic progenitor cells were refractory to FLT3ITD-mediated transformation in vitro

  7. E6201 markedly reduced leukemia burden and improved the survival of mice in a human FLT3-mutated AML (show RUNX1 Antibodies) model.

  8. Proteasome inhibitors induce FLT3-ITD degradation through autophagy in AML (show RUNX1 Antibodies) cells.

  9. Results show FLT3, NPM1 (show NPM1 Antibodies), and CEBPA (show CEBPA Antibodies) combination genotype confer favourable prognosis in AML (show RUNX1 Antibodies)

  10. loss of BEX1 (show BEX1 Antibodies) expression in FLT3-ITD driven AML (show RUNX1 Antibodies) potentiates oncogenic signaling and leads to decreased overall survival

FLT3 Antigen Profile

Antigen Summary

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. The receptor consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, and a cytoplasmic kinase domain split into two parts by a kinase-insert domain. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.

Alternative names and synonyms associated with FLT3

  • fms-related tyrosine kinase 3 (FLT3) antibody
  • FMS-like tyrosine kinase 3 (Flt3) antibody
  • fms-related tyrosine kinase 3 (Flt3) antibody
  • B230315G04 antibody
  • CD135 antibody
  • FLK-2 antibody
  • FLK2 antibody
  • Flt-3 antibody
  • FLT3 antibody
  • Ly72 antibody
  • STK1 antibody
  • wmfl antibody

Protein level used designations for FLT3

fms-related tyrosine kinase 3 , FL cytokine receptor-like , FL cytokine receptor , fetal liver kinase 2 , receptor-type tyrosine-protein kinase FLT3 , tyrosine-protein kinase FLT3 , tyrosine-protein kinase receptor flk-2 , CD135 antigen , STK-1 , fms-like tyrosine kinase 3 , growth factor receptor tyrosine kinase type III , stem cell tyrosine kinase 1 , FMS-like tyrosine kinase 3

452508 Pan troglodytes
100061780 Equus caballus
100413316 Callithrix jacchus
14255 Mus musculus
2322 Homo sapiens
140635 Rattus norvegicus
486025 Canis lupus familiaris
512700 Bos taurus
100858422 Gallus gallus
100515445 Sus scrofa
100732047 Cavia porcellus
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