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Browse our FLT3 (FLT3) ELISA Kits

Full name:
Fms-Related tyrosine Kinase 3 ELISA Kits (FLT3)
On www.antibodies-online.com are 39 Fms-Related tyrosine Kinase 3 (FLT3) ELISA Kits from 13 different suppliers available. Additionally we are shipping FLT3 Antibodies (351) and FLT3 Proteins (26) and many more products for this protein. A total of 427 FLT3 products are currently listed.
Synonyms:
B230315G04, CD135, FLK-2, FLK2, Flt-3, FLT3, Ly72, STK1, wmfl
list all ELISA KIts Gene Name GeneID UniProt
FLT3 14255 Q00342
FLT3 2322 P36888
FLT3 140635  

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More ELISA Kits for FLT3 Interaction Partners

Mouse (Murine) Fms-Related tyrosine Kinase 3 (FLT3) interaction partners

  1. DNMT3A (show DNMT3A ELISA Kits) haploinsufficiency results in reversible epigenetic alterations that transform FLT3(ITD)-mutant myeloproliferative neoplasm into AML (show RUNX1 ELISA Kits).

  2. murine Fms-like tyrosine kinase 3 (Flt3) ligand (show FLT3LG ELISA Kits) was used to generate conventional dendritic cells (FL-cDCs) and plasmacytoid DCs (FL-pDCs) and further evaluated their immunological responses to bacillus Calmette-Guerin (BCG (show SLC11A1 ELISA Kits)) infection in vitro.

  3. increased number of osteoclasts in Flt3L (show FLT3LG ELISA Kits)(-/-) mice may be a consequence of insufficient expression of interferon regulatory factor 8 (show IRF8 ELISA Kits)

  4. FLT3-tandem duplication mutation directly affects dendritic cell development, indirectly modulating T cell homeostasis and supporting T reg (show KCNH2 ELISA Kits) cell expansion.

  5. MYB (show MYB ELISA Kits) and C/EBPalpha (show CEBPA ELISA Kits) activities are inter-dependent in controlling Flt3 expression to influence lineage commitment of multipotential progenitors.

  6. functional synergy between Flt3 and IL-4R signaling is critical for Stat-mediated regulation of sterile gamma1 germ-line transcripts and CSR to IgG1

  7. STAT5 (show STAT5A ELISA Kits) activation by FLT3-ITD protects cells treated with the PI3K/Akt (show AKT1 ELISA Kits) pathway inhibitors from apoptosis by maintaining Mcl-1 (show MCL1 ELISA Kits) expression through the mTORC1/4EBP1 (show EIF4EBP1 ELISA Kits)/eIF4E (show EIF4E ELISA Kits) pathway.

  8. LAMTOR2 (show LAMTOR2 ELISA Kits) has a role in regulating dendritic cell homeostasis through FLT3-dependent mTOR (show FRAP1 ELISA Kits) signalling

  9. The Ras-PI3Kgamma (show PIK3CG ELISA Kits)-Akt (show AKT1 ELISA Kits)-mTOR (show FRAP1 ELISA Kits) signaling axis acts downstream of FLT3L (show FLT3LG ELISA Kits) signaling and is required for development of lung CD103 (show ITGAE ELISA Kits)(+)and CD11b (show ITGAM ELISA Kits)(+) dendritic cells. This signaling network regulating tissue-specific DC development is mediated by FLT3.

  10. These results reveal a leukemic pathway involving FAK (show PTK2 ELISA Kits)/Tiam1/Rac1/PAK1 (show PAK1 ELISA Kits) and demonstrate an essential role for these signaling molecules in regulating the nuclear translocation of Stat5 (show STAT5A ELISA Kits) in leukemogenesis.

Human Fms-Related tyrosine Kinase 3 (FLT3) interaction partners

  1. Prevalence of FLT3-ITD mutation in acute myeloid leukemia (show BCL11A ELISA Kits) was present in a proportion comparable to other populations and, when present, was associated with a very poor prognosis.

  2. PI3K (show PIK3CA ELISA Kits)/AKT (show AKT1 ELISA Kits) signaling only occurs when FLT3-ITD is expressed at the plasma membrane and is required for the production of NOX-generated ROS (show ROS1 ELISA Kits). ER retention of FLT3-ITD resulted in NOX4 (show NOX4 ELISA Kits) deglycosylation and p22(phox (show CYBA ELISA Kits)) protein degradation.

  3. This study evaluated FLT3 internal tandem duplication mutation along with FLT3 expression in acute myeloid leukaemia (AML (show RUNX1 ELISA Kits)) patients, and associated with survival. Negative impact of FLT3 surface expression on survival was observed in AML (show RUNX1 ELISA Kits) patients who were FLT3 ITD negative

  4. FLT3 mutation is associated with acute myeloid leukemia (show BCL11A ELISA Kits).

  5. In vitro, uremia induced dysregulation of DNA methylation in differentiating monocytes, which affected several transcription regulators important for monocyte differentiation (e.g., FLT3, HDAC1, MNT) and led to enhanced generation of intermediate monocytes.

  6. null variant for neutrophil count) are generalizable to WBC traits in Hispanics/Latinos. We identified and replicated common and rare germ-line variants at FLT3 (a gene often somatically mutated in leukemia) associated with monocyte count. The common FLT3 variant rs76428106 has a large allele frequency differential between African and non-African populations

  7. Predictive value of pretransplantation molecular minimal residual disease assessment by WT1 (show WT1 ELISA Kits) gene expression in FLT3-positive acute myeloid leukemia (show BCL11A ELISA Kits).

  8. DNMT3A (show DNMT3A ELISA Kits) haploinsufficiency results in reversible epigenetic alterations that transform FLT3(ITD)-mutant myeloproliferative neoplasm into AML (show RUNX1 ELISA Kits).

  9. Results show that deletion of Dnmt3a (show DNMT3A ELISA Kits) cooperates with FLT3- internal tandem duplication to initiate both myeloid and lymphoid leukemias.

  10. In pediatric patients with AML (show RUNX1 ELISA Kits) from Argentina, a favorable prognosis of AML (show RUNX1 ELISA Kits) with genotype NPM1 (show NPM1 ELISA Kits)-mutated/FLT3-ITD-negative was confirmed.

FLT3 Antigen Profile

Antigen Summary

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. The receptor consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, and a cytoplasmic kinase domain split into two parts by a kinase-insert domain. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.

Alternative names and synonyms associated with FLT3

  • fms-related tyrosine kinase 3 (FLT3) Elisa Kit
  • FMS-like tyrosine kinase 3 (Flt3) Elisa Kit
  • fms-related tyrosine kinase 3 (Flt3) Elisa Kit
  • B230315G04 Elisa Kit
  • CD135 Elisa Kit
  • FLK-2 Elisa Kit
  • FLK2 Elisa Kit
  • Flt-3 Elisa Kit
  • FLT3 Elisa Kit
  • Ly72 Elisa Kit
  • STK1 Elisa Kit
  • wmfl Elisa Kit

Protein level used designations for FLT3

fms-related tyrosine kinase 3 , FL cytokine receptor-like , FL cytokine receptor , fetal liver kinase 2 , receptor-type tyrosine-protein kinase FLT3 , tyrosine-protein kinase FLT3 , tyrosine-protein kinase receptor flk-2 , CD135 antigen , STK-1 , fms-like tyrosine kinase 3 , growth factor receptor tyrosine kinase type III , stem cell tyrosine kinase 1 , FMS-like tyrosine kinase 3

GENE ID SPECIES
452508 Pan troglodytes
100061780 Equus caballus
100413316 Callithrix jacchus
14255 Mus musculus
2322 Homo sapiens
140635 Rattus norvegicus
486025 Canis lupus familiaris
512700 Bos taurus
100858422 Gallus gallus
100515445 Sus scrofa
100732047 Cavia porcellus
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