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Browse our FLT3 (FLT3) ELISA Kits

Full name:
Fms-Related tyrosine Kinase 3 ELISA Kits (FLT3)
On www.antibodies-online.com are 31 Fms-Related tyrosine Kinase 3 (FLT3) ELISA Kits from 10 different suppliers available. Additionally we are shipping FLT3 Antibodies (324) and FLT3 Proteins (24) and many more products for this protein. A total of 389 FLT3 products are currently listed.
Synonyms:
B230315G04, CD135, FLK-2, FLK2, Flt-3, FLT3, Ly72, STK1, wmfl
list all ELISA KIts Gene Name GeneID UniProt
FLT3 14255 Q00342
FLT3 2322 P36888
FLT3 140635  

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More ELISA Kits for FLT3 Interaction Partners

Mouse (Murine) Fms-Related tyrosine Kinase 3 (FLT3) interaction partners

  1. increased number of osteoclasts in Flt3L (show FLT3LG ELISA Kits)(-/-) mice may be a consequence of insufficient expression of interferon regulatory factor 8 (show IRF8 ELISA Kits)

  2. FLT3-tandem duplication mutation directly affects dendritic cell development, indirectly modulating T cell homeostasis and supporting T reg (show KCNH2 ELISA Kits) cell expansion.

  3. MYB (show MYB ELISA Kits) and C/EBPalpha (show CEBPA ELISA Kits) activities are inter-dependent in controlling Flt3 expression to influence lineage commitment of multipotential progenitors.

  4. functional synergy between Flt3 and IL-4R signaling is critical for Stat-mediated regulation of sterile gamma1 germ-line transcripts and CSR to IgG1

  5. STAT5 (show STAT5A ELISA Kits) activation by FLT3-ITD protects cells treated with the PI3K/Akt (show AKT1 ELISA Kits) pathway inhibitors from apoptosis by maintaining Mcl-1 (show MCL1 ELISA Kits) expression through the mTORC1/4EBP1 (show EIF4EBP1 ELISA Kits)/eIF4E (show EIF4E ELISA Kits) pathway.

  6. LAMTOR2 (show LAMTOR2 ELISA Kits) has a role in regulating dendritic cell homeostasis through FLT3-dependent mTOR (show FRAP1 ELISA Kits) signalling

  7. The Ras-PI3Kgamma (show PIK3CG ELISA Kits)-Akt (show AKT1 ELISA Kits)-mTOR (show FRAP1 ELISA Kits) signaling axis acts downstream of FLT3L (show FLT3LG ELISA Kits) signaling and is required for development of lung CD103 (show ITGAE ELISA Kits)(+)and CD11b (show ITGAM ELISA Kits)(+) dendritic cells. This signaling network regulating tissue-specific DC development is mediated by FLT3.

  8. These results reveal a leukemic pathway involving FAK (show PTK2 ELISA Kits)/Tiam1/Rac1/PAK1 (show PAK1 ELISA Kits) and demonstrate an essential role for these signaling molecules in regulating the nuclear translocation of Stat5 (show STAT5A ELISA Kits) in leukemogenesis.

  9. Accumulation of FLT3(+) CD11c (show ITGAX ELISA Kits) (+) dendritic cells in psoriatic lesions and the anti-psoriatic effect of a selective FLT3 inhibitor

  10. Hes1 suppresses acute myeloid leukemia (show BCL11A ELISA Kits) development through FLT3 repression.

Human Fms-Related tyrosine Kinase 3 (FLT3) interaction partners

  1. Molecular docking studies suggest the involvement of Leu616, Asp698, Cys694 and Cys828 residues in binding of G-11 to FLT3. The ability of G-11 to cause selective cytotoxicity and induce differentiation in cancer cells could be clinically relevant

  2. Mutations in FLT3 internal tandem duplication is associated with Acute Myeloid Leukemia (show BCL11A ELISA Kits).

  3. Retroviral expression of FLT3-N676K in myeloid 32D cells induced AML (show RUNX1 ELISA Kits) in syngeneic C3H/HeJ mice. 3 of 14 C57BL/6J mice transplanted with FLT3-N676K-transduced primary hematopoietic progenitor cells developed acute leukemia.

  4. Nox4 (show NOX4 ELISA Kits) knockout (Nox4 (show NOX4 ELISA Kits)(-/-)) murine hematopoietic progenitor cells were refractory to FLT3ITD-mediated transformation in vitro

  5. E6201 markedly reduced leukemia burden and improved the survival of mice in a human FLT3-mutated AML (show RUNX1 ELISA Kits) model.

  6. Proteasome inhibitors induce FLT3-ITD degradation through autophagy in AML (show RUNX1 ELISA Kits) cells.

  7. Results show FLT3, NPM1 (show NPM1 ELISA Kits), and CEBPA (show CEBPA ELISA Kits) combination genotype confer favourable prognosis in AML (show RUNX1 ELISA Kits)

  8. loss of BEX1 (show BEX1 ELISA Kits) expression in FLT3-ITD driven AML (show RUNX1 ELISA Kits) potentiates oncogenic signaling and leads to decreased overall survival

  9. Our results suggest that the CD34 (show CD34 ELISA Kits)/CD25 (show IL2RA ELISA Kits)/CD123 (show IL3RA ELISA Kits)/CD99 (show CD99 ELISA Kits)(+) LAIP is strictly associated with FLT3-ITD-positive cells.

  10. cooperation between the MAP kinase (MAPK (show MAPK1 ELISA Kits)) inducible transcription factor AP-1 (show JUN ELISA Kits) and RUNX1 (show RUNX1 ELISA Kits) as a major driver of a common, FLT3-ITD-specific gene expression and chromatin signature, demonstrating a major impact of MAPK (show MAPK1 ELISA Kits) signaling pathways

FLT3 Antigen Profile

Antigen Summary

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. The receptor consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, and a cytoplasmic kinase domain split into two parts by a kinase-insert domain. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.

Alternative names and synonyms associated with FLT3

  • fms-related tyrosine kinase 3 (FLT3) Elisa Kit
  • FMS-like tyrosine kinase 3 (Flt3) Elisa Kit
  • fms-related tyrosine kinase 3 (Flt3) Elisa Kit
  • B230315G04 Elisa Kit
  • CD135 Elisa Kit
  • FLK-2 Elisa Kit
  • FLK2 Elisa Kit
  • Flt-3 Elisa Kit
  • FLT3 Elisa Kit
  • Ly72 Elisa Kit
  • STK1 Elisa Kit
  • wmfl Elisa Kit

Protein level used designations for FLT3

fms-related tyrosine kinase 3 , FL cytokine receptor-like , FL cytokine receptor , fetal liver kinase 2 , receptor-type tyrosine-protein kinase FLT3 , tyrosine-protein kinase FLT3 , tyrosine-protein kinase receptor flk-2 , CD135 antigen , STK-1 , fms-like tyrosine kinase 3 , growth factor receptor tyrosine kinase type III , stem cell tyrosine kinase 1 , FMS-like tyrosine kinase 3

GENE ID SPECIES
452508 Pan troglodytes
100061780 Equus caballus
100413316 Callithrix jacchus
14255 Mus musculus
2322 Homo sapiens
140635 Rattus norvegicus
486025 Canis lupus familiaris
512700 Bos taurus
100858422 Gallus gallus
100515445 Sus scrofa
100732047 Cavia porcellus
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