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Browse our Galectin 3 Proteins (LGALS3)

Full name:
Lectin, Galactoside-Binding, Soluble, 3 Proteins (LGALS3)
On www.antibodies-online.com are 60 Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) Proteins from 19 different suppliers available. Additionally we are shipping Galectin 3 Antibodies (455) and Galectin 3 Kits (83) and many more products for this protein. A total of 616 Galectin 3 products are currently listed.
Synonyms:
CBP35, CBP 35, Gal-3, GAL3, galactoside-binding, GALBP, galectin-3, GALIG, GBP, L-34, L31, lectin, leg3, LGALS2, LGALS3, Mac-2, MAC2, MGC52947, MGC75803, soluble
list all proteins Gene Name GeneID UniProt
LGALS3 16854  
LGALS3 3958 P17931
LGALS3 83781 P08699

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Galectin 3 Proteins (LGALS3) by Origin

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Top referenced Galectin 3 Proteins

  1. Mouse (Murine) Galectin 3 Protein expressed in Escherichia coli (E. coli) - ABIN2667418 : Henderson, Mackinnon, Farnworth, Poirier, Russo, Iredale, Haslett, Simpson, Sethi: Galectin-3 regulates myofibroblast activation and hepatic fibrosis. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)
    Show all 7 references for ABIN2667418

  2. Human Galectin 3 Protein expressed in Escherichia coli (E. coli) - ABIN2667416 : Gao, Simpson, Zhang, Gibson: Galectin-3: its role in asthma and potential as an anti-inflammatory target. in Respiratory research 2013 (PubMed)
    Show all 7 references for ABIN2667416

  3. Human Galectin 3 Protein expressed in Escherichia coli (E. coli) - ABIN666905 : Kadrofske, Openo, Wang: The human LGALS3 (galectin-3) gene: determination of the gene structure and functional characterization of the promoter. in Archives of biochemistry and biophysics 1998 (PubMed)
    Show all 2 references for ABIN666905

  4. Mouse (Murine) Galectin 3 Protein expressed in Escherichia coli (E. coli) - ABIN1098459 : Barondes, Cooper, Gitt, Leffler: Galectins. Structure and function of a large family of animal lectins. in The Journal of biological chemistry 1994 (PubMed)
    Show all 2 references for ABIN1098459

More Proteins for Galectin 3 Interaction Partners

Xenopus laevis Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) interaction partners

  1. Mutational tuning of galectin-3 specificity and biological function.

Mouse (Murine) Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) interaction partners

  1. Gal-3 expression promotes acute colitis and plays an important pro-inflammatory role in the induction phase of colitis by promoting the activation of NLRP3 (show NLRP3 Proteins) inflammasome and production of IL-1beta (show IL1B Proteins) in macrophages.

  2. mechanistic insights into the regulation of Lgals3, demonstrating that C-terminal binding protein (CtBP (show CTBP2 Proteins)) is required to drive optimal KLF3 (show KLF3 Proteins)-mediated silencing.

  3. analysis of the effect of low-temperature plasma on the expression of galectin-1 (show LGALS1 Proteins), -2, and -3 in the healing skin compared with those of electrocoagulation conducted with a high-frequency electrical coagulator

  4. Our results suggest that the absence of Gal-3 plays an important role in the survival of retinal ganglion cells

  5. Compared with the control, hypoxia increased the mRNA and protein expression levels of Gal3 in wild type murine pulmonary arteries. Gal3 deletion reduced the hypoxiainduced upregulation of right ventricular systolic pressure and Fulton's index.

  6. Study shows that circulating Gal3 levels are elevated in obese mice and humans and that Gal3 is a macrophage-derived factor that can cause in vivo systemic insulin (show INS Proteins) resistance both acutely and chronically.

  7. we have validated a novel gene, Myh14, as a negative regulator of ISO-induced left ventricular mass hypertrophy in an in vivo mouse model and demonstrated the up-regulation of immediate early gene Myc, fetal gene Nppb, and fibrosis gene Lgals3 in ISO-treated Myh14 deficient hearts compared to controls.

  8. The results very comprehensively demonstrate distinct signaling pathways that regulate microfilament organization, lamellipodial structures, spreading, and movement of cells plated on galectin-3 as opposed to fibronectin (show FN1 Proteins).

  9. Galectin-3 plays a protective role in the pathways that lead to the inflammatory destruction of biliary epithelial cells.

  10. a novel role is revealed for galectin-3 in controlling the expression of surface IgA.

Human Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) interaction partners

  1. CD146/MCAM (show MCAM Proteins) is the functional galectin-3-binding ligand on endothelial cell surfaces responsible for galectin-3-induced secretion of metastasis-promoting cytokines.

  2. Gal-3 expression promotes acute colitis and plays an important pro-inflammatory role in the induction phase of colitis by promoting the activation of NLRP3 (show NLRP3 Proteins) inflammasome and production of IL-1beta (show IL1B Proteins) in macrophages.

  3. Elevated plasma galectin-3 levels are strongly associated with the inflammation, severity and poor prognosis after intracerebral hemorrhage, indicating galectin-3, involved in brain inflammation, might have the potential to be a prognostic biomarker for hemorrhagic stroke

  4. Gal-3 may represent a novel biomarker for right ventricular remodeling and associated extracellular matrix turnover in pulmonary artery hypertension.

  5. Gal-3 interacts with unmodified heparin, chondroitin sulfate-A (CSA), -B (CSB), and -C (CSC) as well as chondroitin sulfate proteoglycans (CSPGs)

  6. High galectin-3 expression is associated with obesity.

  7. Suggest galectin-3 level as predictor of prognostic outcomes for non-ischemic cardiomyopathy patients.

  8. serum galectin-3 was an independent unfavorable factor for relapse-free survival in patients with APL (show FASL Proteins) treated with all-trans retinoic acid and arsenic trioxide-based frontline therapy.

  9. Gal3 inhibition by small interfering RNA alleviated the hypoxiainduced inflammatory response in HPAECs, including tumor necrosis factoralpha and interleukin1 secretion, expression of intercellular adhesion molecule1 and adhesion of THP1 monocytes.

  10. Differential expression of LGALS1 (show LGALS1 Proteins) and/or LGALS3 in patients with myeloproliferative neoplasm (MPN (show PRSS27 Proteins)) is linked with JAK2 (show JAK2 Proteins) V617F status mutation in these diseases and state of cell differentiation.

Rabbit Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) interaction partners

  1. Demonstrate that galectin-3 plays a critical role in hensin (show DMBT1 Proteins) ECM (show MMRN1 Proteins) assembly by oligomerizing secreted monomeric hensin (show DMBT1 Proteins).

Cow (Bovine) Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) interaction partners

  1. The overall findings suggest that the secreted galectin-3 stimulated by PGF (show PGF Proteins) plays a role in structural luteolysis by binding to beta 1 integrin.

  2. The relative abundance of PIBF (show PIBF1 Proteins), LGALS1 (show LGALS1 Proteins), LGALS3 (show LGALS2 Proteins), LGALS3BP (show LGALS3BP Proteins), and LGALS9 (show LGALS9 Proteins) mRNA would display a differential expression pattern in the endometrium.

Galectin 3 (LGALS3) Protein Profile

Protein Summary

This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with Galectin 3 (LGALS3)

  • lectin, galactoside-binding, soluble, 3 (lgals3)
  • lectin, galactoside-binding, soluble, 2 (LGALS2)
  • lectin, galactoside-binding, soluble, 3 (LGALS3)
  • Galectin-3 (leg3)
  • lectin, galactose binding, soluble 3 (Lgals3)
  • lectin, galactoside-binding, soluble, 3 (Lgals3)
  • CBP35 protein
  • CBP 35 protein
  • Gal-3 protein
  • GAL3 protein
  • galactoside-binding protein
  • GALBP protein
  • galectin-3 protein
  • GALIG protein
  • GBP protein
  • L-34 protein
  • L31 protein
  • lectin protein
  • leg3 protein
  • LGALS2 protein
  • LGALS3 protein
  • Mac-2 protein
  • MAC2 protein
  • MGC52947 protein
  • MGC75803 protein
  • soluble protein

Protein level used designations for LGALS3

lectin, galactoside-binding, soluble, 3 , galectin 3 , lectin, galactoside-binding, soluble, 2 , Galectin-3 , 35 kDa lectin , CBP 35 , L-34 galactoside-binding lectin , carbohydrate-binding protein 35 , gal-3 , galactose-specific lectin 3 , galectin-3 , igE-binding protein , laminin-binding protein , lectin L-29 , mac-2 antigen , IgE-binding protein , MAC-2 antigen , IgE binding protein , lectin, galactose binding, soluble 3 , beta-galactosides-binding lectin , lectin, galactoside-binding, soluble, 3 (galectin 3) , 3 (galectin 3)

GENE ID SPECIES
379330 Xenopus laevis
394583 Xenopus (Silurana) tropicalis
470204 Pan troglodytes
744038 Pan troglodytes
100195804 Salmo salar
16854 Mus musculus
3958 Homo sapiens
83781 Rattus norvegicus
697290 Macaca mulatta
100009187 Oryctolagus cuniculus
404021 Canis lupus familiaris
100217393 Sus scrofa
786492 Bos taurus
100736029 Cavia porcellus
373917 Gallus gallus
101118449 Ovis aries
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