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Browse our Galectin 3 Proteins (LGALS3)

Full name:
Lectin, Galactoside-Binding, Soluble, 3 Proteins (LGALS3)
On are 63 Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) Proteins from 19 different suppliers available. Additionally we are shipping Galectin 3 Antibodies (467) and Galectin 3 Kits (79) and many more products for this protein. A total of 626 Galectin 3 products are currently listed.
CBP35, CBP 35, Gal-3, GAL3, galactoside-binding, GALBP, galectin-3, GALIG, GBP, L-34, L31, lectin, leg3, LGALS2, LGALS3, Mac-2, MAC2, MGC52947, MGC75803, soluble
list all proteins Gene Name GeneID UniProt
LGALS3 16854  
LGALS3 3958 P17931
LGALS3 83781 P08699

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Galectin 3 Proteins (LGALS3) by Origin

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Top referenced Galectin 3 Proteins

  1. Mouse (Murine) Galectin 3 Protein expressed in Escherichia coli (E. coli) - ABIN2667418 : Henderson, Mackinnon, Farnworth, Poirier, Russo, Iredale, Haslett, Simpson, Sethi: Galectin-3 regulates myofibroblast activation and hepatic fibrosis. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)
    Show all 7 references for ABIN2667418

  2. Human Galectin 3 Protein expressed in Escherichia coli (E. coli) - ABIN2667416 : Gao, Simpson, Zhang, Gibson: Galectin-3: its role in asthma and potential as an anti-inflammatory target. in Respiratory research 2013 (PubMed)
    Show all 7 references for ABIN2667416

  3. Human Galectin 3 Protein expressed in Escherichia coli (E. coli) - ABIN666905 : Kadrofske, Openo, Wang: The human LGALS3 (galectin-3) gene: determination of the gene structure and functional characterization of the promoter. in Archives of biochemistry and biophysics 1998 (PubMed)
    Show all 2 references for ABIN666905

  4. Mouse (Murine) Galectin 3 Protein expressed in Escherichia coli (E. coli) - ABIN1098459 : Barondes, Cooper, Gitt, Leffler: Galectins. Structure and function of a large family of animal lectins. in The Journal of biological chemistry 1994 (PubMed)
    Show all 2 references for ABIN1098459

More Proteins for Galectin 3 Interaction Partners

Xenopus laevis Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) interaction partners

  1. Mutational tuning of galectin-3 specificity and biological function.

Mouse (Murine) Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) interaction partners

  1. The results very comprehensively demonstrate distinct signaling pathways that regulate microfilament organization, lamellipodial structures, spreading, and movement of cells plated on galectin-3 as opposed to fibronectin (show FN1 Proteins).

  2. Galectin-3 plays a protective role in the pathways that lead to the inflammatory destruction of biliary epithelial cells.

  3. a novel role is revealed for galectin-3 in controlling the expression of surface IgA.

  4. Loss of Gal-3 blocked chemokine (show CCL1 Proteins) increases after Theiler's murine encephalomyelitis virus infection, reduced immune cell migration into the zone (SVZ), reestablished SVZ proliferation and increased the number of progenitors in the corpus callosum

  5. Gal3 facilitates mast cell adhesion and motility.Gal3 regulates IgE internalization and trafficking to endolysosomes.

  6. These data demonstrate that Gal3 plays an important role in innate immunity to infection and colonization of H. pylori.

  7. the disruption in the inflammatory cells migration in the absence of galectin-3 is a crucial event in the formation and organization of oil granulomas.

  8. The present study provides evidence of a novel role for Gal-3 in regulating IL-33 (show IL33 Proteins)-dependent liver fibrosis.

  9. A critical role of macrophages and their galectin 3 in controlling acute viral-induced cardiac injury and the subsequent fibrosis.

  10. B-cell precursor acute lymphoblastic leukemia and stromal cells communicate through galectin-3 signaling.

Human Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) interaction partners

  1. Galectin-3 was upregulated in expression and S-nitrosylation, which may indicate its potential role in mucosal inflammation in Esophageal Eosinophilia.

  2. Blood concentration of galectin-3 is not a useful biomarker in the diagnosis of acute heart failure.

  3. Increased galectin-3 levels are associated with ambulatory ECG-based MTWA positivity, decreased estimated glomerular filtration rate, and increased LVMI in hypertensive patients.

  4. It is a beta-galactose-binding animal lectin and known to be distributed throughout the body.

  5. Lower levels of both galectin-3 and osteopontin (show SPP1 Proteins) are associated with successful aging, representing potential biomarkers of this condition.

  6. analysis of LGALS3, PHB2, MUC1, and GK2 expression with CA15-3 in early-stage breast cancer

  7. LGALS3 and AXIN1 (show AXIN1 Proteins) genes affect tumor sizes and the mucinous component via Wnt (show WNT2 Proteins)/ beta-catenin (show CTNNB1 Proteins) pathway in the pathogenesis of colorectal cancer

  8. These data indicate that knockdown of LIcadherin facilitates the invasion of cancer cells by degrading extracellular matrix components via activation of MMP2 (show MMP2 Proteins) and 9, and increases cancer cell adhesion and migration via altered expression of galectin3.

  9. Gal-3 may affect the migratory and invasive capabilities of cancer cells as well as the chemosensitiviy to carboplatin in epithelial ovarian cancer

  10. Gal-3 demonstrates a prognostic role independently from renal dysfunction in subjects with HFpEF

Rabbit Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) interaction partners

  1. Demonstrate that galectin-3 plays a critical role in hensin (show DMBT1 Proteins) ECM (show MMRN1 Proteins) assembly by oligomerizing secreted monomeric hensin (show DMBT1 Proteins).

Cow (Bovine) Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) interaction partners

  1. The overall findings suggest that the secreted galectin-3 stimulated by PGF (show PGF Proteins) plays a role in structural luteolysis by binding to beta 1 integrin.

  2. The relative abundance of PIBF (show PIBF1 Proteins), LGALS1 (show LGALS1 Proteins), LGALS3 (show LGALS2 Proteins), LGALS3BP (show LGALS3BP Proteins), and LGALS9 (show LGALS9 Proteins) mRNA would display a differential expression pattern in the endometrium.

Galectin 3 (LGALS3) Protein Profile

Protein Summary

This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with Galectin 3 (LGALS3)

  • lectin, galactoside-binding, soluble, 3 (lgals3)
  • lectin, galactoside-binding, soluble, 2 (LGALS2)
  • lectin, galactoside-binding, soluble, 3 (LGALS3)
  • Galectin-3 (leg3)
  • lectin, galactose binding, soluble 3 (Lgals3)
  • lectin, galactoside-binding, soluble, 3 (Lgals3)
  • CBP35 protein
  • CBP 35 protein
  • Gal-3 protein
  • GAL3 protein
  • galactoside-binding protein
  • GALBP protein
  • galectin-3 protein
  • GALIG protein
  • GBP protein
  • L-34 protein
  • L31 protein
  • lectin protein
  • leg3 protein
  • LGALS2 protein
  • LGALS3 protein
  • Mac-2 protein
  • MAC2 protein
  • MGC52947 protein
  • MGC75803 protein
  • soluble protein

Protein level used designations for LGALS3

lectin, galactoside-binding, soluble, 3 , galectin 3 , lectin, galactoside-binding, soluble, 2 , Galectin-3 , 35 kDa lectin , CBP 35 , L-34 galactoside-binding lectin , carbohydrate-binding protein 35 , gal-3 , galactose-specific lectin 3 , galectin-3 , igE-binding protein , laminin-binding protein , lectin L-29 , mac-2 antigen , IgE-binding protein , MAC-2 antigen , IgE binding protein , lectin, galactose binding, soluble 3 , beta-galactosides-binding lectin , lectin, galactoside-binding, soluble, 3 (galectin 3) , 3 (galectin 3)

379330 Xenopus laevis
394583 Xenopus (Silurana) tropicalis
470204 Pan troglodytes
744038 Pan troglodytes
100195804 Salmo salar
16854 Mus musculus
3958 Homo sapiens
83781 Rattus norvegicus
697290 Macaca mulatta
100009187 Oryctolagus cuniculus
404021 Canis lupus familiaris
100217393 Sus scrofa
786492 Bos taurus
100736029 Cavia porcellus
373917 Gallus gallus
101118449 Ovis aries
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