Browse our Galectin 3 Proteins (LGALS3)

Full name:
Lectin, Galactoside-Binding, Soluble, 3 Proteins (LGALS3)
On are 67 Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) Proteins from 19 different suppliers available. Additionally we are shipping Galectin 3 Antibodies (484) and Galectin 3 Kits (105) and many more products for this protein. A total of 675 Galectin 3 products are currently listed.
CBP35, CBP 35, Gal-3, GAL3, galactoside-binding, GALBP, galectin-3, GALIG, GBP, L-34, L31, lectin, leg3, LGALS2, LGALS3, Mac-2, MAC2, MGC52947, MGC75803, soluble
list all proteins Gene Name GeneID UniProt
LGALS3 16854  
LGALS3 3958 P17931
LGALS3 83781 P08699

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Galectin 3 Proteins (LGALS3) by Origin

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Top referenced Galectin 3 Proteins

  1. Human Galectin 3 Protein expressed in Escherichia coli (E. coli) - ABIN2667416 : Gao, Simpson, Zhang, Gibson: Galectin-3: its role in asthma and potential as an anti-inflammatory target. in Respiratory research 2013 (PubMed)
    Show all 7 references for 2667416

  2. Mouse (Murine) Galectin 3 Protein expressed in Escherichia coli (E. coli) - ABIN2667418 : Henderson, Mackinnon, Farnworth, Poirier, Russo, Iredale, Haslett, Simpson, Sethi: Galectin-3 regulates myofibroblast activation and hepatic fibrosis. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)
    Show all 7 references for 2667418

  3. Human Galectin 3 Protein expressed in Escherichia coli (E. coli) - ABIN666905 : Kadrofske, Openo, Wang: The human LGALS3 (galectin-3) gene: determination of the gene structure and functional characterization of the promoter. in Archives of biochemistry and biophysics 1998 (PubMed)
    Show all 2 references for 666905

  4. Mouse (Murine) Galectin 3 Protein expressed in Escherichia coli (E. coli) - ABIN1098459 : Barondes, Cooper, Gitt, Leffler: Galectins. Structure and function of a large family of animal lectins. in The Journal of biological chemistry 1994 (PubMed)
    Show all 2 references for 1098459

More Proteins for Galectin 3 Interaction Partners

Xenopus laevis Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) interaction partners

  1. Mutational tuning of galectin-3 specificity and biological function.

Mouse (Murine) Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) interaction partners

  1. Data demonstrated that the absence of host galectin-3 drastically affected the tumor biology favoring the metastatic spreading of 4T1 cells to inguinal lymph nodes and bone marrow colonization.

  2. study demonstrated that endogenous Gal-3 is specifically involved in leukocyte slow rolling

  3. Gal-3 influences remyelination by mechanisms involving the tuning of microglial cells, modulation of MMP activity, and changes in myelin architecture.

  4. These data indicate a role for endogenous Gal-3 in neutrophil clearance during acute inflammation.

  5. Our results suggest that endogenous galectin-3 regulates Notch (show NOTCH1 Proteins) signaling activation in bone marrow-derived dendritic cells and influences polarization of T helper responses

  6. Results suggest that prion protein PrPC (show PRNP Proteins) combined with galectin-3 and -6 can act as a receptor for murine leukemia virus (MuLV).

  7. This study indicates that the ANG II (show AGT Proteins) effects are, in part, mediated or triggered by Gal-3 together with the related intercellular signaling (ICAM-1 (show ICAM1 Proteins) and IL-6 (show IL6 Proteins)), leading to cardiac inflammation and fibrosis.

  8. Regulation of complement 5a receptor (C5aR (show C5AR1 Proteins))-induced neutrophil chemotaxis via IgG1 immune complexes (ICs (show DNAI1 Proteins)) depends on galectin-3.

  9. Gal-3 expression promotes acute colitis and plays an important pro-inflammatory role in the induction phase of colitis by promoting the activation of NLRP3 (show NLRP3 Proteins) inflammasome and production of IL-1beta (show IL1B Proteins) in macrophages.

  10. mechanistic insights into the regulation of Lgals3, demonstrating that C-terminal binding protein (CtBP (show CTBP2 Proteins)) is required to drive optimal KLF3 (show KLF3 Proteins)-mediated silencing.

Human Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) interaction partners

  1. a novel role of Gal3 as an initiator of inflammatory signaling in autoimmune cholangitis, mediating the activation of NOD-like receptor family, pyrin domain containing 3 inflammasome and inducing IL-17 (show IL17A Proteins) proinflammatory cascades

  2. Galectin-3 levels and cystatin-C (show CST3 Proteins) levels are independent predictors of 26-month mortality in patients with chronic heart failure

  3. The current study supports the tumor suppression role of galectin-3 in endometrial carcinoma

  4. Data suggest that galectin-3 (usually an elevated plasma/serum level of galectin-3) is emerging as a promising biomarker for outcome prediction and for guidance therapy in patients with acute coronary syndrome. [REVIEW]

  5. in at least some breast cancers, loss of Gal3 might be associated with EMT (show ITK Proteins) and cancer stemness-associated traits, predicts poor response to chemotherapy, and poor prognosis.

  6. Galectin-3 levels are higher in peripheral arterial disease.

  7. in combination with fusion proteins suitable for the design of diagnostic and therapeutic tools binding properties can be beneficially tuned. The resulting novel protein tools may be advantageous for potential galectin-3 directed applications in tumor diagnostics and therapy.

  8. Variation of GAL-3 serum levels related to single nucleotide polymorphism at +191 and +292 may constitute a susceptibility factor for respiratory tract infection and vaso-occlusion and respiratory tract infection frequency.

  9. Gal-3 was up-regulated in myocardial biopsies from aortic stenosis patients compared with controls.

  10. Galectin-3 (Gal-3) is a beta (show SUCLA2 Proteins)-galactoside-binding lectin (show LGALS13 Proteins) that is expressed in a variety of cells and plays a central role in inflammation and fibrosis.

Rabbit Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) interaction partners

  1. Demonstrate that galectin-3 plays a critical role in hensin (show DMBT1 Proteins) ECM (show MMRN1 Proteins) assembly by oligomerizing secreted monomeric hensin (show DMBT1 Proteins).

Cow (Bovine) Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) interaction partners

  1. The overall findings suggest that the secreted galectin-3 stimulated by PGF (show PGF Proteins) plays a role in structural luteolysis by binding to beta 1 integrin.

  2. The relative abundance of PIBF (show PIBF1 Proteins), LGALS1 (show LGALS1 Proteins), LGALS3 (show LGALS2 Proteins), LGALS3BP (show LGALS3BP Proteins), and LGALS9 (show LGALS9 Proteins) mRNA would display a differential expression pattern in the endometrium.

Galectin 3 (LGALS3) Protein Profile

Protein Summary

This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with Galectin 3 (LGALS3)

  • lectin, galactoside-binding, soluble, 3 (lgals3)
  • lectin, galactoside-binding, soluble, 2 (LGALS2)
  • lectin, galactoside-binding, soluble, 3 (LGALS3)
  • Galectin-3 (leg3)
  • lectin, galactose binding, soluble 3 (Lgals3)
  • lectin, galactoside-binding, soluble, 3 (Lgals3)
  • CBP35 protein
  • CBP 35 protein
  • Gal-3 protein
  • GAL3 protein
  • galactoside-binding protein
  • GALBP protein
  • galectin-3 protein
  • GALIG protein
  • GBP protein
  • L-34 protein
  • L31 protein
  • lectin protein
  • leg3 protein
  • LGALS2 protein
  • LGALS3 protein
  • Mac-2 protein
  • MAC2 protein
  • MGC52947 protein
  • MGC75803 protein
  • soluble protein

Protein level used designations for LGALS3

lectin, galactoside-binding, soluble, 3 , galectin 3 , lectin, galactoside-binding, soluble, 2 , Galectin-3 , 35 kDa lectin , CBP 35 , L-34 galactoside-binding lectin , carbohydrate-binding protein 35 , gal-3 , galactose-specific lectin 3 , galectin-3 , igE-binding protein , laminin-binding protein , lectin L-29 , mac-2 antigen , IgE-binding protein , MAC-2 antigen , IgE binding protein , lectin, galactose binding, soluble 3 , beta-galactosides-binding lectin , lectin, galactoside-binding, soluble, 3 (galectin 3) , 3 (galectin 3)

379330 Xenopus laevis
394583 Xenopus (Silurana) tropicalis
470204 Pan troglodytes
744038 Pan troglodytes
100195804 Salmo salar
16854 Mus musculus
3958 Homo sapiens
83781 Rattus norvegicus
697290 Macaca mulatta
100009187 Oryctolagus cuniculus
404021 Canis lupus familiaris
100217393 Sus scrofa
786492 Bos taurus
100736029 Cavia porcellus
373917 Gallus gallus
101118449 Ovis aries
Selected quality suppliers for Galectin 3 Proteins (LGALS3)
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