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Browse our Galectin 3 Proteins (LGALS3)

Full name:
Lectin, Galactoside-Binding, Soluble, 3 Proteins (LGALS3)
On www.antibodies-online.com are 60 Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) Proteins from 19 different suppliers available. Additionally we are shipping Galectin 3 Antibodies (457) and Galectin 3 Kits (89) and many more products for this protein. A total of 625 Galectin 3 products are currently listed.
Synonyms:
CBP35, CBP 35, Gal-3, GAL3, galactoside-binding, GALBP, galectin-3, GALIG, GBP, L-34, L31, lectin, leg3, LGALS2, LGALS3, Mac-2, MAC2, MGC52947, MGC75803, soluble
list all proteins Gene Name GeneID UniProt
LGALS3 16854  
LGALS3 3958 P17931
LGALS3 83781 P08699

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Galectin 3 Proteins (LGALS3) by Origin

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Top referenced Galectin 3 Proteins

  1. Mouse (Murine) Galectin 3 Protein expressed in Escherichia coli (E. coli) - ABIN2667418 : Henderson, Mackinnon, Farnworth, Poirier, Russo, Iredale, Haslett, Simpson, Sethi: Galectin-3 regulates myofibroblast activation and hepatic fibrosis. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)
    Show all 7 references for ABIN2667418

  2. Human Galectin 3 Protein expressed in Escherichia coli (E. coli) - ABIN2667416 : Gao, Simpson, Zhang, Gibson: Galectin-3: its role in asthma and potential as an anti-inflammatory target. in Respiratory research 2013 (PubMed)
    Show all 7 references for ABIN2667416

  3. Human Galectin 3 Protein expressed in Escherichia coli (E. coli) - ABIN666905 : Kadrofske, Openo, Wang: The human LGALS3 (galectin-3) gene: determination of the gene structure and functional characterization of the promoter. in Archives of biochemistry and biophysics 1998 (PubMed)
    Show all 2 references for ABIN666905

  4. Mouse (Murine) Galectin 3 Protein expressed in Escherichia coli (E. coli) - ABIN1098459 : Barondes, Cooper, Gitt, Leffler: Galectins. Structure and function of a large family of animal lectins. in The Journal of biological chemistry 1994 (PubMed)
    Show all 2 references for ABIN1098459

More Proteins for Galectin 3 Interaction Partners

Xenopus laevis Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) interaction partners

  1. Mutational tuning of galectin-3 specificity and biological function.

Mouse (Murine) Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) interaction partners

  1. This study indicates that the ANG II (show AGT Proteins) effects are, in part, mediated or triggered by Gal-3 together with the related intercellular signaling (ICAM-1 (show ICAM1 Proteins) and IL-6 (show IL6 Proteins)), leading to cardiac inflammation and fibrosis.

  2. Regulation of complement 5a receptor (C5aR (show C5AR1 Proteins))-induced neutrophil chemotaxis via IgG1 immune complexes (ICs (show DNAI1 Proteins)) depends on galectin-3.

  3. Gal-3 expression promotes acute colitis and plays an important pro-inflammatory role in the induction phase of colitis by promoting the activation of NLRP3 (show NLRP3 Proteins) inflammasome and production of IL-1beta (show IL1B Proteins) in macrophages.

  4. mechanistic insights into the regulation of Lgals3, demonstrating that C-terminal binding protein (CtBP (show CTBP2 Proteins)) is required to drive optimal KLF3 (show KLF3 Proteins)-mediated silencing.

  5. analysis of the effect of low-temperature plasma on the expression of galectin-1 (show LGALS1 Proteins), -2, and -3 in the healing skin compared with those of electrocoagulation conducted with a high-frequency electrical coagulator

  6. Our results suggest that the absence of Gal-3 plays an important role in the survival of retinal ganglion cells

  7. Compared with the control, hypoxia increased the mRNA and protein expression levels of Gal3 in wild type murine pulmonary arteries. Gal3 deletion reduced the hypoxiainduced upregulation of right ventricular systolic pressure and Fulton's index.

  8. Study shows that circulating Gal3 levels are elevated in obese mice and humans and that Gal3 is a macrophage-derived factor that can cause in vivo systemic insulin (show INS Proteins) resistance both acutely and chronically.

  9. we have validated a novel gene, Myh14, as a negative regulator of ISO-induced left ventricular mass hypertrophy in an in vivo mouse model and demonstrated the up-regulation of immediate early gene Myc, fetal gene Nppb, and fibrosis gene Lgals3 in ISO-treated Myh14 deficient hearts compared to controls.

  10. The results very comprehensively demonstrate distinct signaling pathways that regulate microfilament organization, lamellipodial structures, spreading, and movement of cells plated on galectin-3 as opposed to fibronectin (show FN1 Proteins).

Human Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) interaction partners

  1. the A allele of rs4644, which mimics the findings in galectin-3 ablated cells, was associated with lower EV71 titers in our cellular model, and clinically the AA genotype was protective against higher levels of hyperglycemia, an indicator for severe EV71 infection.

  2. Galectin-3 did not provide prognostic information on the occurrence of aortic stenosis-related events.

  3. Gal 3 is reasonably supposed to be a part of those mechanisms leading to formation, destabilization and rupture of plaque; however, the usefulness of Gal 3 as a biomarker in CAD/AMI (show CFD Proteins) is far from being elucidated.

  4. The cooperation between TRIM16 (show TRIM16 Proteins) and Galectin-3 in targeting and activation of selective autophagy protects cells from lysosomal damage and Mycobacterium tuberculosis invasion.

  5. These results indicate that the galectin-3-U1 snRNP (show LSM2 Proteins)-pre-mRNA ternary complex is a functional E complex and that U1 snRNP (show LSM2 Proteins) is required to assemble galectin-3 onto an active spliceosome

  6. Galectin-3-induced cell death in HIV-1-infected macrophages is most likely related to the translocation of Endo G (show ENDOG Proteins) from the cytoplasm to the nucleus.

  7. Plasma Gal-3 levels are enhanced after aneurysmal subarachnoid hemorrhage (aSAH (show ASAH1 Proteins)) and correlated positively with severity scores. Gal-3 levels independently predict 6-month mortality and unfavorable outcome with a high predictive value. Thus, Gal-3 may aid in predicting the risk of poor prognosis in patients with aSAH (show ASAH1 Proteins).

  8. Myocardial Gal-3 can be considered as a possible marker for both cardiac inflammation and fibrosis, depending on the pathogenesis of heart failure. However, circulating concentrations of Gal-3 do not seem to reflect endomyocardial Gal-3 levels or cardiac fibrosis.

  9. Galectin-1 (show LGALS1 Proteins) and Galectin-3 are novel-binding partners for human FVIII (show F8 Proteins). Gal-1 (show LGALS1 Proteins) binding can influence the procoagulant activity of FVIII (show F8 Proteins).

  10. CD146/MCAM (show MCAM Proteins) is the functional galectin-3-binding ligand on endothelial cell surfaces responsible for galectin-3-induced secretion of metastasis-promoting cytokines.

Rabbit Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) interaction partners

  1. Demonstrate that galectin-3 plays a critical role in hensin (show DMBT1 Proteins) ECM (show MMRN1 Proteins) assembly by oligomerizing secreted monomeric hensin (show DMBT1 Proteins).

Cow (Bovine) Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) interaction partners

  1. The overall findings suggest that the secreted galectin-3 stimulated by PGF (show PGF Proteins) plays a role in structural luteolysis by binding to beta 1 integrin.

  2. The relative abundance of PIBF (show PIBF1 Proteins), LGALS1 (show LGALS1 Proteins), LGALS3 (show LGALS2 Proteins), LGALS3BP (show LGALS3BP Proteins), and LGALS9 (show LGALS9 Proteins) mRNA would display a differential expression pattern in the endometrium.

Galectin 3 (LGALS3) Protein Profile

Protein Summary

This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with Galectin 3 (LGALS3)

  • lectin, galactoside-binding, soluble, 3 (lgals3)
  • lectin, galactoside-binding, soluble, 2 (LGALS2)
  • lectin, galactoside-binding, soluble, 3 (LGALS3)
  • Galectin-3 (leg3)
  • lectin, galactose binding, soluble 3 (Lgals3)
  • lectin, galactoside-binding, soluble, 3 (Lgals3)
  • CBP35 protein
  • CBP 35 protein
  • Gal-3 protein
  • GAL3 protein
  • galactoside-binding protein
  • GALBP protein
  • galectin-3 protein
  • GALIG protein
  • GBP protein
  • L-34 protein
  • L31 protein
  • lectin protein
  • leg3 protein
  • LGALS2 protein
  • LGALS3 protein
  • Mac-2 protein
  • MAC2 protein
  • MGC52947 protein
  • MGC75803 protein
  • soluble protein

Protein level used designations for LGALS3

lectin, galactoside-binding, soluble, 3 , galectin 3 , lectin, galactoside-binding, soluble, 2 , Galectin-3 , 35 kDa lectin , CBP 35 , L-34 galactoside-binding lectin , carbohydrate-binding protein 35 , gal-3 , galactose-specific lectin 3 , galectin-3 , igE-binding protein , laminin-binding protein , lectin L-29 , mac-2 antigen , IgE-binding protein , MAC-2 antigen , IgE binding protein , lectin, galactose binding, soluble 3 , beta-galactosides-binding lectin , lectin, galactoside-binding, soluble, 3 (galectin 3) , 3 (galectin 3)

GENE ID SPECIES
379330 Xenopus laevis
394583 Xenopus (Silurana) tropicalis
470204 Pan troglodytes
744038 Pan troglodytes
100195804 Salmo salar
16854 Mus musculus
3958 Homo sapiens
83781 Rattus norvegicus
697290 Macaca mulatta
100009187 Oryctolagus cuniculus
404021 Canis lupus familiaris
100217393 Sus scrofa
786492 Bos taurus
100736029 Cavia porcellus
373917 Gallus gallus
101118449 Ovis aries
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