Galectin 3 Protein (LGALS3) (AA 2-264) (His tag)

Catalog No. ABIN7505372

Product Details

Target: Galectin 3 (LGALS3)

Protein Type: Recombinant

Protein Characteristics: AA 2-264

Origin: Mouse

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This Galectin 3 protein is labelled with His tag.

Sequence: Ala2-Ile264

Characteristics: A DNA sequence encoding the Mouse Galectin-3/Lgals3 protein (P16110) (2A-264I) was expressed with a polyhistidine tag at the N-terminus.

Purity: >90 % as determined by reducing SDS-PAGE.

Application Details

Comment:

used as Immunogen for (ABIN6999921, ABIN7234295, ABIN7234296 and ABIN7234297)

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: Galectin 3 (LGALS3)

Alternative Name: Galectin-3 (LGALS3 Products)

Synonyms: CBP 35 Protein, Gal-3 Protein, Galectin-3 Protein, leg3 Protein, galactoside-binding Protein, galectin-3 Protein, lectin Protein, soluble Protein, CBP35 Protein, GAL3 Protein, GALBP Protein, GALIG Protein, L31 Protein, LGALS2 Protein, MAC2 Protein, MGC52947 Protein, MGC75803 Protein, LGALS3 Protein, gal-3 Protein, GBP Protein, L-34 Protein, Mac-2 Protein, gal3 Protein, galectin 3 Protein, Galectin-3 Protein, avian beta-defensin 3 Protein, lectin, galactoside-binding, soluble, 3 L homeolog Protein, lectin, galactoside-binding, soluble, 3 Protein, galectin 2 Protein, lectin, galactose binding, soluble 3 Protein, LGALS3 Protein, leg3 Protein, AvBD3 Protein, lgals3.L Protein, lgals3 Protein, LGALS2 Protein, Lgals3 Protein

Target Type: Chemical

Background:

Background: Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes.

Synonym: 35 kDa lectin,Carbohydrate binding protein 35,CBP35,GAL3,GALBP,GALIG,GBP,Gal-3,IgE binding protein,LGALS2,Macrophage galactose-specific lectin,Lectin L-29,Mac-2 antigen

Molecular Weight: 27.4 kDa

UniProt: P16110

Pathways: RTK Signaling