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anti-Rat (Rattus) GDNF Antibodies:
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Human Polyclonal GDNF Primary Antibody for IF (p), IHC (p) - ABIN736536
Zhang, Cai, Song, Dong, Hou, Lv: Normalization of ventral tegmental area structure following acupuncture in a rat model of heroin relapse. in Neural regeneration research 2014
Human Polyclonal GDNF Primary Antibody for EIA, WB - ABIN453664
Tomac, Lindqvist, Lin, Ogren, Young, Hoffer, Olson: Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo. in Nature 1995
The present research concluded that aspirin suppressed prostate cancer cell invasion by reducing MMP-9 (show MMP9 Antibodies) activity and uPA (show PRAP1 Antibodies) expression through decreasing of IKK-beta (show IKBKB Antibodies)-mediated NF-kappaB (show NFKB1 Antibodies) activation, indicating that the ability of aspirin to inhibit cell invasion might be useful in the chemoprevention of metastatic prostate cancer.
Suppression of miR (show MLXIP Antibodies)-383 may increase the therapeutic potential of human bone-marrow-derived MSCs in treating spinal cord injury via augmentation of GDNF protein levels.
These studies identify uPA (show PRAP1 Antibodies)-dependent de-repression of vegfr1 (show FLT1 Antibodies) and vegfr2 (show KDR Antibodies) gene transcription through binding to HHEX/PRH (show HHEX Antibodies) as a novel mechanism by which uPA (show PRAP1 Antibodies) mediates the pro-angiogenic effects of VEGF (show VEGFA Antibodies) and identifies a potential new target for control of pathologic angiogenesis.
Our results suggest that GDNF rs3096140 might be involved in the genetic background of smoking, independent of anxiety characteristics.
No correlations between the levels of serum neurotrophins and the severity of ADHD were observed. These results suggest that elevated serum GDNF and NTF3 (show NTF3 Antibodies) levels may be related to ADHD in children.
BDNF (show BDNF Antibodies) and GDNF interact with the 5-HT (show DDC Antibodies)-system of the brain through feedback mechanisms engaged in autoregulation
We concluded that overexpression of MMP-3 (show MMP3 Antibodies) and uPA (show PRAP1 Antibodies), altogether with diminished expression of PAI-1 (show SERPINE1 Antibodies) from metastatic tumors, might be a crucial step towards metastasis in ductal breast cancer.
The up-regulation of uPA (show PRAP1 Antibodies) mRNAs was correlated with high-risk clinicopathological features, including extrathyroid invasion, loss of cellular polarity/cohesiveness, and the BRAF (show BRAF Antibodies)(V600E) mutation.
the synergistic effect of Gas1 (show GAS1 Antibodies) inhibition and GDNF against glutamate (show GRIN1 Antibodies)-induced cell injury in human SH-SY5Y neuroblastoma (show ARHGEF16 Antibodies) cells, is reported.
In contrast to platelet-derived growth factor, all urokinase isoforms induced secretion of MMP-9 (show MMP9 Antibodies) by mesenchymal stromal cells.
GDNF signals were able to induce the stratified aggregate formation of GFRalpha1 (show GFRA1 Antibodies)-positive undifferentiated spermatogonia
Our results show the existence of two subpopulations of peptidergic nociceptors characterized by the presence of CGRP (show CALCA Antibodies), one expressing BDNF (show BDNF Antibodies) (plus SP), the other expressing GDNF (plus SST (show SST Antibodies)), suggesting a different role for these two neurotrophic factors in the discrimination of specific painful stimuli modalities.
The data of this study suggested that short-term exposure to hyperoxic conditions can affect the regulation and expression of BDNF (show BDNF Antibodies) potentially leading to alterations in neural development.
The Gdnf cKO males sired up to two litters but became infertile due to collapse of spermatogenesis and loss of undifferentiated spermatogonia
Our results reveal the role of GDNF in nigrostriatal dopamine system postnatal development and adult function, and highlight the importance of correct spatial expression of GDNF
Mice overexpressing GDNF had significantly reduced P62 (show GTF2H1 Antibodies) protein levels suggestive of accelerated autophagy. They also had reduced PPAR-gamma (show PPARG Antibodies) and CD36 (show CD36 Antibodies) gene expression and protein levels, and lower expression of mRNA coding for enzymes involved lipogenesis.
This study demonstrated that decrease in mRNA level of GDNF in brain in microgravity.
GDNF signaling in the urogenital sinus increases proliferation.
Results show that in the inflamed intestine, smooth muscle proliferation supports the enteric nervous system , and thus its own re-innervation, by expression of GDNF
Parkin (show PARK2 Antibodies) and the RET (show RET Antibodies) signaling cascade converge to control mitochondrial integrity and thereby properly maintain substantia nigra pars (show EPRS Antibodies) compacta dopaminergic neurons and their innervation in the striatum.
This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, Glial cell line derived neutrophic factor
, astrocyte-derived trophic factor
, glial cell line derived neurotrophic factor
, glial cell line-derived neurotrophic factor
, neurotrophic factor
, U-plasminogen activator
, plasminogen activator, urinary
, urokinase-type plasminogen activator