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Browse our GDNF Proteins (GDNF)

Full name:
Glial Cell Derived Neurotrophic Factor Proteins (GDNF)
On www.antibodies-online.com are 0 Glial Cell Derived Neurotrophic Factor (GDNF) Proteins from different suppliers available. Additionally we are shipping GDNF Antibodies (1) and many more products for this protein. A total of 1 GDNF products are currently listed.
Synonyms:
AI385739, ATF1, ATF2, gdnf, gdnfa, HFB1-GDNF, HSCR3
list all proteins Gene Name GeneID UniProt
Human GDNF GDNF 2668 P39905
Rat GDNF GDNF 25453 Q07731
Mouse GDNF GDNF 14573 P48540

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More Proteins for GDNF Interaction Partners

Rhesus Monkey Glial Cell Derived Neurotrophic Factor (GDNF) interaction partners

  1. Analysis of striatal brain samples confirms increased GDNF expression in lentiviral vector-GDNF treated aged animals that correlates with functional improvements and preserved dopaminergic markers, dependent upon GDNF levels.

Xenopus laevis Glial Cell Derived Neurotrophic Factor (GDNF) interaction partners

  1. Spatial expression analysis by whole-mount in situ hybridization showed that the GDNF mRNA was predominantly detected in somites, pronephros, pharyngeal arches, epibranchial placodes, digestive tract and some of the lateral line structure.

Human Glial Cell Derived Neurotrophic Factor (GDNF) interaction partners

  1. These results demonstrate the pivotal role of GDNF as well as the PI3K (show PIK3CA Proteins)/Akt (show AKT1 Proteins) pathway, but not the MAPK (show MAPK1 Proteins) pathway, in the prevention of diabetesinduced neuronal apoptosis in the hippocampus.

  2. Increased plasma levels of GDNF were found in untreated attention deficit hyperactivity disorder patients.

  3. GDNF levels were lower in the ECT responders compared with pre-ECT levels

  4. The GDNF polymorphism rs3096140 is associated with Tourette syndrome.

  5. GDNF levels were significantly higher in mania and lower in schizophrenia compared to healthy controls. BDNF (show BDNF Proteins) levels were negatively correlated to illness severity scores in affective episodes

  6. Data indicate that glial cell-derived neurotrophic factor (GDNF) was down-regulated in the medullary sponge kidney (MSK) cells.

  7. Osteogenic features of MSCs from ossification of yellow ligament patients are promoted by un-methylated GDNF.

  8. The glial cell line-derived neurotrophic factor(GDNF)-induced growth and differentiation of cultured enteric neurons is paralleled by increased expression of SNAP-25 (show SNAP25 Proteins) and formation of synaptic vesicles reflecting enhanced synaptogenesis.

  9. improvement in behavioral performance (open-field and grip-strength tests), as well as increased life-span was observed in rodents treated with NCAM (show NCAM1 Proteins)-VEGF (show VEGFA Proteins) or NCAM (show NCAM1 Proteins)-GDNF co-transfected cells

  10. Data indicate the glial cell derived neurotrophic factor (GDNF) signaling pathway as a potential target for improving responses to conventional genotoxic therapeutics.

Zebrafish Glial Cell Derived Neurotrophic Factor (GDNF) interaction partners

  1. the dynamics of glial cell line-derived neurotrophic factor (gdnf) and nitric oxide synthases (nos (show NOS1 Proteins)) mRNA expression in various regions of zebrafish brain

  2. GDNF family ligands including tyrosine kinase receptor (show KDR Proteins) RET (show RET Proteins) are investigated within the adult zebrafish brain.

  3. GDNF is a major determinant of directed neuritic growth , and GDNF acts by promoting local neurite outgrowth.

  4. These results demonstrated the expression of the GDNF receptorial complex in adult zebrafish cerebellum and suggest an autocrine mode of action of GDNF in Purkinje cells.

  5. These results showed that the expression of GDNF is not probably restricted during development but it might be involved in the physiology of adult zebrafish retina.

  6. The expression of glial cell line-derived neurotrophic factor (GDNF) was not restricted to developmental periods but it seems that this factor might be involved in adult zebrafish brain physiology, as observed in mammals.

Mouse (Murine) Glial Cell Derived Neurotrophic Factor (GDNF) interaction partners

  1. The data of this study suggested that short-term exposure to hyperoxic conditions can affect the regulation and expression of BDNF (show BDNF Proteins) potentially leading to alterations in neural development.

  2. The Gdnf cKO males sired up to two litters but became infertile due to collapse of spermatogenesis and loss of undifferentiated spermatogonia

  3. Our results reveal the role of GDNF in nigrostriatal dopamine system postnatal development and adult function, and highlight the importance of correct spatial expression of GDNF

  4. Mice overexpressing GDNF had significantly reduced P62 (show GTF2H1 Proteins) protein levels suggestive of accelerated autophagy. They also had reduced PPAR-gamma (show PPARG Proteins) and CD36 (show CD36 Proteins) gene expression and protein levels, and lower expression of mRNA coding for enzymes involved lipogenesis.

  5. This study demonstrated that decrease in mRNA level of GDNF in brain in microgravity.

  6. GDNF signaling in the urogenital sinus increases proliferation.

  7. Results show that in the inflamed intestine, smooth muscle proliferation supports the enteric nervous system , and thus its own re-innervation, by expression of GDNF

  8. Parkin (show PARK2 Proteins) and the RET (show RET Proteins) signaling cascade converge to control mitochondrial integrity and thereby properly maintain substantia nigra pars (show EPRS Proteins) compacta dopaminergic neurons and their innervation in the striatum.

  9. expression induced by testosterone in peritubular myoid (show MYO1A Proteins) cells

  10. These data suggest that there are significant changes in the responses to GDNF as spermatogonial stem cells give rise to progenitor spermatogonia.

GDNF Protein Profile

Protein Summary

This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene may be associated with Hirschsprung disease.

Alternative names and synonyms associated with GDNF

  • glial cell derived neurotrophic factor (GDNF)
  • glial cell derived neurotrophic factor (gdnf-a)
  • glial cell derived neurotrophic factor (Gdnf)
  • glial cell derived neurotrophic factor a (gdnfa)
  • glial cell line derived neurotrophic factor (Gdnf)
  • AI385739 protein
  • ATF1 protein
  • ATF2 protein
  • gdnf protein
  • gdnfa protein
  • HFB1-GDNF protein
  • HSCR3 protein

Protein level used designations for GDNF

glial cell derived neurotrophic factor , glial cell line derived neurotrophic factor , glial cell line-derived neurotrophic factor , glial cell line-derived neurotrophic factor a , xGDNF , ATF , astrocyte-derived trophic factor , glial cell line-derived neurotrophic factor long form , Glial cell line derived neutrophic factor , glial cell-line derived neurotrophic factor , glia-derived neurotrophic growth factor , zGDNF , mGDNF , neurotrophic factor

GENE ID SPECIES
471566 Pan troglodytes
706345 Macaca mulatta
779087 Xenopus laevis
2668 Homo sapiens
395569 Gallus gallus
25453 Rattus norvegicus
489224 Canis lupus familiaris
100322894 Sus scrofa
386587 Bos taurus
101117619 Ovis aries
100067053 Equus caballus
79379 Danio rerio
14573 Mus musculus
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