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Browse our GDNF Proteins (GDNF)

Full name:
Glial Cell Line Derived Neurotrophic Factor Proteins (GDNF)
On are 66 Glial Cell Line Derived Neurotrophic Factor (GDNF) Proteins from 18 different suppliers available. Additionally we are shipping GDNF Antibodies (96) and GDNF Kits (85) and many more products for this protein. A total of 257 GDNF products are currently listed.
list all proteins Gene Name GeneID UniProt
GDNF 25453 Q07731
GDNF 2668 P39905
GDNF 14573 P48540

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GDNF Proteins (GDNF) by Origin

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Top referenced GDNF Proteins

  1. Human GDNF Protein expressed in Escherichia coli (E. coli) - ABIN2667420 : Carnicella, Ron: GDNF--a potential target to treat addiction. in Pharmacology & therapeutics 2009 (PubMed)
    Show all 5 references for ABIN2667420

  2. Human GDNF Protein expressed in Escherichia coli (E. coli) - ABIN1686334 : Pelletier, Lagacé, St-Amour, Arsenault, Cisbani, Chabrat, Fecteau, Lévesque, Cicchetti: The morphological and molecular changes of brain cells exposed to direct current electric field stimulation. in The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2015 (PubMed)

More Proteins for GDNF Interaction Partners

Human Glial Cell Line Derived Neurotrophic Factor (GDNF) interaction partners

  1. Increased plasma levels of GDNF were found in untreated attention deficit hyperactivity disorder patients.

  2. Data suggest that enhanced levels of uPA (show PRAP1 Proteins) in breast cancer modulate the mitogenic effects of EGF (show EGF Proteins) which helps to better understand breast cancer pathogenesis.

  3. Results found high levels of uPA (show PRAP1 Proteins) and uPAR (show PLAUR Proteins) exclusively in metastatic osteosarcoma (OS)cells and suggest that malignant conversion of OS cells to uPA (show PRAP1 Proteins)/uPAR (show PLAUR Proteins) axis in an autocrine and paracrine fashion.

  4. GDNF levels were lower in the ECT responders compared with pre-ECT levels

  5. The morphologically normal tissue adjacent to the tumor shows the substantial expression of MMP-2 (show MMP2 Proteins) and MMP-9 (show MMP9 Proteins) and in some cases the enhanced activity of uPA (show PRAP1 Proteins) and ACE (show ACE Proteins), which makes an additional contribution to the increased invasive potential of tumor

  6. The GDNF polymorphism rs3096140 is associated with Tourette syndrome.

  7. Crystal structure of uPA (show PRAP1 Proteins) bound with cyclic peptidic inhibitors.

  8. data on the stromal macrophages immunoreactivity of uPAR (show PLAUR Proteins), MMP-2 (show MMP2 Proteins), and MMP-9 (show MMP9 Proteins) in a few small cell lung cancer (SCLC) and lung squamous cell carcinoma (SCC (show CYP11A1 Proteins)) biopsies was included. uPAR (show PLAUR Proteins), MMP-2 (show MMP2 Proteins), and MMP-9 (show MMP9 Proteins) were confirmed in stromal cells including macrophages

  9. GDNF levels were significantly higher in mania and lower in schizophrenia compared to healthy controls. BDNF (show BDNF Proteins) levels were negatively correlated to illness severity scores in affective episodes

  10. Data indicate that glial cell-derived neurotrophic factor (GDNF) was down-regulated in the medullary sponge kidney (MSK) cells.

Mouse (Murine) Glial Cell Line Derived Neurotrophic Factor (GDNF) interaction partners

  1. The Gdnf cKO males sired up to two litters but became infertile due to collapse of spermatogenesis and loss of undifferentiated spermatogonia

  2. Our results reveal the role of GDNF in nigrostriatal dopamine system postnatal development and adult function, and highlight the importance of correct spatial expression of GDNF

  3. Mice overexpressing GDNF had significantly reduced P62 (show GTF2H1 Proteins) protein levels suggestive of accelerated autophagy. They also had reduced PPAR-gamma (show PPARG Proteins) and CD36 (show CD36 Proteins) gene expression and protein levels, and lower expression of mRNA coding for enzymes involved lipogenesis.

  4. This study demonstrated that decrease in mRNA level of GDNF in brain in microgravity.

  5. GDNF signaling in the urogenital sinus increases proliferation.

  6. Results show that in the inflamed intestine, smooth muscle proliferation supports the enteric nervous system , and thus its own re-innervation, by expression of GDNF

  7. Parkin (show PARK2 Proteins) and the RET (show RET Proteins) signaling cascade converge to control mitochondrial integrity and thereby properly maintain substantia nigra pars (show EPRS Proteins) compacta dopaminergic neurons and their innervation in the striatum.

  8. expression induced by testosterone in peritubular myoid (show MYO1A Proteins) cells

  9. These data suggest that there are significant changes in the responses to GDNF as spermatogonial stem cells give rise to progenitor spermatogonia.

  10. The transcriptional start site and the promoter activity of the 5'-flanking region of GDNF have been identified.

GDNF Protein Profile

Protein Summary

This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with GDNF

  • glial cell derived neurotrophic factor (Gdnf)
  • glial cell derived neurotrophic factor (GDNF)
  • glial cell line derived neurotrophic factor (Gdnf)
  • plasminogen activator, urokinase (PLAU)
  • AI385739 protein
  • ATF protein
  • ATF1 protein
  • ATF2 protein
  • BDPLT5 protein
  • HFB1-GDNF protein
  • HSCR3 protein
  • QPD protein
  • u-PA protein
  • UPA protein
  • URK protein

Protein level used designations for GDNF

ATF , Glial cell line derived neutrophic factor , astrocyte-derived trophic factor , glial cell line derived neurotrophic factor , glial cell line-derived neurotrophic factor , mGDNF , neurotrophic factor , U-plasminogen activator , plasminogen activator, urinary , urokinase-type plasminogen activator

25453 Rattus norvegicus
2668 Homo sapiens
14573 Mus musculus
5328 Homo sapiens
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