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Browse our GRB2 (GRB2) ELISA Kits

Full name:
Growth Factor Receptor-Bound Protein 2 ELISA Kits (GRB2)
On www.antibodies-online.com are 36 Growth Factor Receptor-Bound Protein 2 (GRB2) ELISA Kits from 9 different suppliers available. Additionally we are shipping GRB2 Antibodies (153) and GRB2 Proteins (23) and many more products for this protein. A total of 221 GRB2 products are currently listed.
Synonyms:
AA408164, ASH, EGFRBP-GRB2, grb2, Grb3-3, MST084, MSTP084, NCKAP2, wu:fb18e12, wu:fb34e06, zgc:73077

More ELISA Kits for GRB2 Interaction Partners

Mouse (Murine) Growth Factor Receptor-Bound Protein 2 (GRB2) interaction partners

  1. Grb2-deficient T cells show defects in T cell development, increased Th1 (show HAND1 ELISA Kits) and Th17 cell differentiation capacities, and impaired proliferation after activation by dendritic cells, which likely reduce the clinical symptoms of EAE.

  2. provide evidence that CD28 (show CD28 ELISA Kits) and the TCR complex regulate NF-kappaB (show NFKB1 ELISA Kits) via different signaling modules of GRB-2/VAV1 (show VAV1 ELISA Kits) and LAT (show LAT ELISA Kits)/ADAP (show APP ELISA Kits) pathways respectively.

  3. GRB2 physically links cyt (show CYGB ELISA Kits)-PTPe (show PTPRE ELISA Kits) with Src (show SRC ELISA Kits) and enables cyt (show CYGB ELISA Kits)-PTPe (show PTPRE ELISA Kits) to activate Src (show SRC ELISA Kits) downstream of activated integrins in osteoclast-like cells.

  4. SUMOylation of Grb2 enhances the ERK (show EPHB2 ELISA Kits) activity by increasing its binding with Sos1 (show SOS1 ELISA Kits).

  5. Data indicate that growth factor receptor (show RYK ELISA Kits) protein binding protein 2 (Grb2) is upregulated and regulated by Forkhead Box D3 (Foxd3 (show FOXD3 ELISA Kits)), and pregulated Grb2 interacts with huntingtin (Htt (show HTT ELISA Kits)).

  6. Grb2 contributes to immunoreceptor tyrosine-based activation motif signaling in platelets during hemostasis and thrombosis.

  7. Findings indicate Grb2 as a new FAK (show PTK2 ELISA Kits) activator and in coordinating PTPalpha (show PTPRA ELISA Kits) tyrosine phosphorylation to enable downstream integrin signaling and migration.

  8. Grb2 is not required for the establishment of the glomerular filtration barrier in vivo.

  9. Study shows that the ability of Sos1/Grb2 to appropriately regulate pluripotency and differentiation factors and to initiate primitive endoderm development requires collective binding of multiple Sos1/Grb2 domains to their protein and phospholipid ligands.

  10. findings suggest a novel role for GRB2 in ecotropic MLV entry and infection by facilitating mCAT-1 (show SLC7A1 ELISA Kits) trafficking

Human Growth Factor Receptor-Bound Protein 2 (GRB2) interaction partners

  1. Genetic variation near GRB2 on chromosome 17q25.1 is associated with sight-threatening diabetic retinopathy.

  2. Only monomeric Grb2 is capable of upregulating MAP kinase (show MAPK1 ELISA Kits) signalling. The dimeric state is inhibitory to this process. The self-association/dissociation of Grb2 represents a switch that regulates MAP kinase (show MAPK1 ELISA Kits) activity and hence controls cancer progression.

  3. The immunoglobulin tail tyrosine motif in the cytoplasmic segments of membrane-bound IgGs acts as the principle signal amplifier by incorporating a Grb2-Btk (show BTK ELISA Kits) signaling.

  4. findings show that regions outside of the consensus PxxPxR sites drive the high affinity association of GRB2 with SH3 domain (show ITSN1 ELISA Kits) ligands

  5. down-regulated molecule growth factor receptor-bound protein 2 (GRB2) was a prominent node in fourteen cell proliferation-related sub-pathways.

  6. C-SH3 of Grb2 mediates the interaction with mutant Htt (show HTT ELISA Kits) and this interaction being stronger could replace Gab1, with mutant Htt (show HTT ELISA Kits) becoming the preferred partner. This would have immense effect on downstream signaling events.

  7. GRB2 was an independent factor in prognosis of esophageal squamous cell carcinoma patients

  8. In addition, GRB2 and UBC (show RPS27A ELISA Kits) were found to be hub nodes in the differentially expressed subnetwork and may be used as potential biomarkers or targets for the diagnosis of bladder cancer.

  9. The N-terminal SH3 domain (show ITSN1 ELISA Kits) of Grb2 specifically interacts with UVRAG, unlike the C-terminal SH3 domain (show ITSN1 ELISA Kits). This interaction helps to understand the role of Grb2 in the autophagic maturation of vesicles.

  10. Knockdown of GRB2 suppressed LMTK3-induced CDC42 activation, blocked ITGA5 and ITGB1 expression promoted by the transcription factor serum response factor (SRF), and reduced invasive activity

Pig (Porcine) Growth Factor Receptor-Bound Protein 2 (GRB2) interaction partners

  1. in VSMCs exposed to hyperglycemia, IGF-I (show IGF1 ELISA Kits) stimulation of Shc (show SHC1 ELISA Kits) facilitates the transfer of Grb2 to p85 (show ARHGEF7 ELISA Kits) resulting in enhanced PI3K activation and AKT (show AKT1 ELISA Kits) phosphorylation leading to enhanced cell proliferation and migration

GRB2 Antigen Profile

Antigen Summary

The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with GRB2

  • growth factor receptor-bound protein 2 (GRB2) Elisa Kit
  • Growth factor receptor-bound protein 2 (grb2) Elisa Kit
  • growth factor receptor-bound protein 2 (grb2) Elisa Kit
  • growth factor receptor bound protein 2 (Grb2) Elisa Kit
  • growth factor receptor-bound protein 2 (LOC100342500) Elisa Kit
  • growth factor receptor-bound protein 2 (Grb2) Elisa Kit
  • growth factor receptor-bound protein 2b (grb2b) Elisa Kit
  • AA408164 Elisa Kit
  • ASH Elisa Kit
  • EGFRBP-GRB2 Elisa Kit
  • grb2 Elisa Kit
  • Grb3-3 Elisa Kit
  • MST084 Elisa Kit
  • MSTP084 Elisa Kit
  • NCKAP2 Elisa Kit
  • wu:fb18e12 Elisa Kit
  • wu:fb34e06 Elisa Kit
  • zgc:73077 Elisa Kit

Protein level used designations for GRB2

growth factor receptor-bound protein 2 , Growth factor receptor-bound protein 2 , SH2/SH3 adapter GRB2 , adapter protein GRB2 , protein Ash , HT027 , abundant SRC homology , epidermal growth factor receptor-binding protein GRB2 , growth factor receptor-bound protein 3 , growth factor receptor bound protein 2 , fb18e12

GENE ID SPECIES
737245 Pan troglodytes
100306767 Salmo salar
100528114 Ictalurus punctatus
14784 Mus musculus
81504 Rattus norvegicus
2885 Homo sapiens
483312 Canis lupus familiaris
535298 Bos taurus
100342500 Oryctolagus cuniculus
100715453 Cavia porcellus
100192436 Sus scrofa
386572 Gallus gallus
101109893 Ovis aries
100173972 Pongo abelii
406308 Danio rerio
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