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Rat (Rattus) IGF1 ELISA Kit for Sandwich ELISA - ABIN416242
Al-Massadi, Trujillo, Señaris, Pardo, Castelao, Casanueva, Seoane: The vagus nerve as a regulator of growth hormone secretion. in Regulatory peptides 2010
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Human IGF1 ELISA Kit for Sandwich ELISA - ABIN625003
Aucouturier, Thivel, Isacco, Fellmann, Chardigny, Duclos, Duché: Combined food intake and exercise unmask different hormonal responses in lean and obese children. in Applied physiology, nutrition, and metabolism = Physiologie appliquée, nutrition et métabolisme 2013
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Human IGF1 ELISA Kit for Sandwich ELISA - ABIN365302
A Hamid, Mohamed Ali, Yusof, George: Platelet-rich plasma (PRP): an adjuvant to hasten hamstring muscle recovery. A randomized controlled trial protocol (ISCRTN66528592). in BMC musculoskeletal disorders 2012
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Rat (Rattus) IGF1 ELISA Kit for Sandwich ELISA - ABIN411285
Ozdemir, Baykara, Aksu, Kiray, Sisman, Cetin, Dayi, Gurpinar, Uysal, Arda: Relationship between circulating IGF-1 levels and traumatic brain injury-induced hippocampal damage and cognitive dysfunction in immature rats. in Neuroscience letters 2012
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Human IGF1 ELISA Kit for Sandwich ELISA - ABIN414866
Serafín, Agüí, Yáñez-Sedeño, Pingarrón: Electrochemical immunosensor for the determination of insulin-like growth factor-1 using electrodes modified with carbon nanotubes-poly(pyrrole propionic acid) hybrids. in Biosensors & bioelectronics 2013
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Cow (Bovine) IGF1 ELISA Kit for Competition ELISA - ABIN364595
Varughese, Brar, Honparkhe, Ghuman: Correlation of blood flow of the preovulatory follicle to its diameter and endocrine profile in dairy buffalo. in Reproduction in domestic animals = Zuchthygiene 2014
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Dog (Canine) IGF1 ELISA Kit for Sandwich ELISA - ABIN414190
Ciftci, Yarim: Evaluation of IGF-I levels and serum protein profiles of diabetic cats and dogs. in Journal of veterinary science 2011
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Mouse (Murine) IGF1 ELISA Kit for Sandwich ELISA - ABIN415497
Señarís, Trujillo, Navia, Comes, Ferrer, Giralt, Hidalgo: Interleukin-6 regulates the expression of hypothalamic neuropeptides involved in body weight in a gender-dependent way. in Journal of neuroendocrinology 2011
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Mouse (Murine) IGF1 ELISA Kit for Sandwich ELISA - ABIN625403
Juffer, Jaspers, Lips, Bakker, Klein-Nulend: Expression of muscle anabolic and metabolic factors in mechanically loaded MLO-Y4 osteocytes. in American journal of physiology. Endocrinology and metabolism 2012
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Rat (Rattus) IGF1 ELISA Kit for Sandwich ELISA - ABIN365381
Tseng, Sung, Chen, Lai, Chang, Sung, Wang: Comparison of chemical compositions and osteoprotective effects of different sections of velvet antler. in Journal of ethnopharmacology 2013
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the dipeptide Pro-Asp (show ASIP ELISA Kits) promoted IGF-1 secretion and expression in hepatocytes.
Genetic variants in the IGF1 and IGF1R (show IGF1R ELISA Kits) genes might not be associated with high myopia in Han Chinese. Further studies are needed to verify the possible function of IGF1 and IGF1R (show IGF1R ELISA Kits) in the development of myopia.
The serum levels of IGF-1 seem to be increased in bipolar disorder patients (248.84+/-104.91ng/mL) compared to controls (169.18+/-74.16ng/mL).
In the present study of older adults, there was some evidence that moderate levels of IGF-1 levels conferred a reduced risk of depression.
The cotreatment of neonate skin fibroblast cultures with galactose and Gal-1 (show LGALS1 ELISA Kits)-P significantly increased cellular levels of NO and iNOS (show NOS2 ELISA Kits) protein expression, and decreased IGF-1 mRNA levels. Treatment with L-NAME, a NOS (show NOS1 ELISA Kits) inhibitor, significantly alleviated a galactose/Gal-1 (show LGALS1 ELISA Kits)-P-induced decrease in IGF-1 mRNA levels. These results suggest that NO mediates the downregulation of IGF-1 by Gal-1 (show LGALS1 ELISA Kits)-P/galactose.
Lower circulating IGF-I is associated with better cognitive function in females with exceptional longevity, with no detriment to skeletal muscle mass and function.
The findings indicated that miR (show MLXIP ELISA Kits)-135a promotes cell apoptosis and inhibits cell proliferation, migration, invasion and tumor angiogenesis by targeting IGF-1 gene through the IGF-1/PI3K (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits) signaling pathway in non-small cell lung cancer.
Enhancing IGF-1 expression by astrocytes provided hippocampal neuroprotection and improved memory and motor function after traumatic brain injury. Delivering IGF-1 through reactive astrocytes targeted IGF-1 overexpression to the damaged hippocampus, producing a progressive increase in IGF-1 over 72 h which led to activation of the Akt (show AKT1 ELISA Kits) pro-survival pathway and reduced hippocampal neuron loss in multiple regions.
IGF-1 signaling is essential for sustaining cancer cell viability by stimulating both mitochondrial biogenesis and turnover through BNIP3 (show BNIP3 ELISA Kits) induction. This core mitochondrial protective signal is likely to strongly influence responses to therapy and the phenotypic evolution of cancer.
Enhanced study of the role of IIS pathway and epigenetic mechanisms that regulate aging may facilitate progressive prevention and treatment of human age-related diseases.
the dipeptide Pro-Asp (show C3 ELISA Kits) promoted IGF-1 secretion and expression in hepatocytes.
miR (show MLXIP ELISA Kits)-18a suppresses the expression of Igf1 in a 3'UTR (show UTS2R ELISA Kits)-dependent manner
down-regulation of IGF-1 expression and signaling is involved in FD-induced cell cycle arrest and apoptosis in HT-22 hippocampal neuron cells
Study demonstrates that GH/IGF-I, somatostatin (show SST ELISA Kits)/cortistatin (show CORT ELISA Kits) and ghrelin (show GHRL ELISA Kits) systems expression is altered in mammary gland during fasting, suggesting a relevant role in coordinating its response to metabolic stress, wherein endogenous cortistatin (show CORT ELISA Kits) might be essential for an appropriate response.
The specific aim of the present work was to study whether the partial IGF-1 deficiency influences heart and/or coronary circulation, comparing vasoactive factors before and after of ischemia-reperfusion (I/R).
Data (including data from studies using heterozygous transgenic mice) suggest that gene expression in liver is altered in a model of inflammation of liver due to partial deficiency of Igf1; this leads to over-expression of Igf1 receptor, inflammation mediators, and acute-phase proteins, but under-expression of cytoskeletal proteins, extracellular matrix proteins, and tight junction proteins.
Findings indicate that the energy-sensing LKB1 (show STK11 ELISA Kits)-AMPK (show PRKAA1 ELISA Kits) pathway regulates IGF1 secretion in mouse primary hepatocytes, which in turn regulates activation of the IGF1R (show IGF1R ELISA Kits)-PKB (show AKT2 ELISA Kits) pathway.
These results demonstrate that a greater than additive effect is observed on the growth of skeletal muscle and in the reduction of body fat when myostatin (show MSTN ELISA Kits) is absent and IGF1 is in excess, and that myostatin (show MSTN ELISA Kits) and IGF1 regulate skeletal muscle size, myofibre type and gonadal fat through distinct mechanisms.
Confirmation of the impairment of GH-IGF-1 release in hyperphagic MC4R (show MC4R ELISA Kits) KO mice suggests a role for insulin (show INS ELISA Kits) in regulating both the release of GH, but also in mediating growth during periods of physiologically suppressed GH-IGF-1 levels
The immunoprecipitation results also showed that high AA concentrations significantly increased the interaction of mTOR (show FRAP1 ELISA Kits) and PPARg (show PPARG ELISA Kits). In summary, PPARg (show PPARG ELISA Kits) plays an important role in the regulation of IGF-1 secretion and gene expression in response to dietary protein.
Data suggest that both ovarian follicular dominance in cows and cooperation of ovarian follicles in pigs can be mediated by either down- or up-regulation of the insulin-like growth factor 1/oxytocin system.
This study demonstrated that Up-regulation of IGF-1 in the frontal cortex of piglets exposed to an environmentally enriched arena.
Combined administration of mesenchymal stem cells overexpressing IGF-1 and HGF (show HGF ELISA Kits) enhances neovascularization but moderately improves cardiac regeneration in a porcine model.
Results show that expression changes of IGF1 genes were associated with C/EBP (show CEBPA ELISA Kits) b expression during embryonic and postnatal development in porcine liver.
genetic association study suggests that the TC genotype of IGF-1 represents the selection genotype for smaller in size.
IGF-I coordinately regulates multiple cell signaling pathways that are critical to proliferation, migration and survival of trophectoderm cells during early pregnancy in pigs.
IGF-1 splice variant (mechano growth factor) is expressed within the growth plate, but the addition of its peptides was not associated with growth plate chondrocytes proliferation.
alpha-linolenic acid increased IGF-I secretion from hepatocytes.
Data suggest caloric restriction modifies response of ovarian granulosa cells to leptin (show LEP ELISA Kits) on cell proliferation/apoptosis, MAP kinase (show MAPK1 ELISA Kits) signaling, and release of hormones (estradiol and IGFI). The caloric restriction studies were conducted in rabbits; then, isolated rabbit granulosa cells were exposed to recombinant human leptin (show LEP ELISA Kits). (IGF1 = insulin-like growth factor I)
Intraplacental gene therapy with Ad-IGF-1 corrects naturally occurring rabbit model of intrauterine growth restriction.
Our studies demonstrate that the active SVCT2 (show SLC23A2 ELISA Kits) is expressed in IVD (show IVD ELISA Kits) cells and that the expression of this transporter is regulated by growth factors IGF-1 and dexamethasone.
increased endogenous IGF1 and IGF2 expression by the blastocyst compensates for the loss of systemic insulin (show INS ELISA Kits) and IGF.
IGF1 showed a significantly higher capacity to form the posterior mesoderm and primitive streak (stage 2 and 3) than blastocysts cultured without growth factors
Overall, IGF-1 promoted atherosclerosis by affecting endothelial function and aging.
Findings show similar regulatory growth hormone (GH (show GH1 ELISA Kits)) and insulin-like growth factor 1 (IGF-1) responses in both Atlantic salmon and rainbow trout.
the present study assessed the combined impacts of estrogens and bacterial infection on the insulin (show INS ELISA Kits)-like growth factors (IGF) and tumor-necrosis factor (TNF)-alpha (show TNF ELISA Kits).
Nutrient availability, IGF-I, and genetic variation affect weight loss, in part through alterations of proteolytic pathways in rainbow trout.
Study demonstrated that IGF-I can stimulate egfr (show EGFR ELISA Kits) expression in both follicles cell culture and intact follicles promoting oocyte maturation.
IGF-I-induced kitlga expression is inhibited by epidermal growth factor (show EGF ELISA Kits), an oocyte-derived paracrine factor in the zebrafish follicle.
hypoxia causes PGC (show PGC ELISA Kits) migration defect by inhibiting IGF signaling through the induction of IGFBP-1 (show IGFBPI ELISA Kits)
Whereas hypoxia repressed the Igf1 receptor and its downstream Erk1/2 (show MAPK1/3 ELISA Kits) and Akt (show AKT1 ELISA Kits) signaling activities, re-oxygenation restored their activities
IGF signalling influences expression of BMP2b (show BMP4 ELISA Kits), a gene that plays an important role in zebrafish pattern formation
The insulin-like growth factor 1 gene can be differentially transcribed to yield two distinct IGF-1 mRNA transcripts
zebrafish XBP-1 (show XBP1 ELISA Kits) spliced form not only activates genes responsible for protein folding, transporting, glycosylation and Endoplasmic Reticulum associated degradation but also activates anti-apoptosis signal via IGF1/Akt (show AKT1 ELISA Kits) pathway in unfolded protein
Thus CR suppresses the hypertrophic PGC1alpha-4/IGF-1/AKT1 pathway while promoting activation of the calpain system.
IGF1 single nucleotide polymorphisms associated with milk fatty acids in a Chinese Holstein cattle.
It has been shown that several specific genes which are differentially regulated, including IGF-1, might impact dairy fertility.
There was no association between the genotypes of GH and IGF-IS and fertility of Holstein cows raised in semiextensive or intensive regimes, while the STAT5 (show STAT5A ELISA Kits) ABstEII polymorphism was associated with calving-first heat interval in Holstein cows raised in the intensive system.
Associations between genetic variants in the promoter region of the insulin-like growth factor-1 (IGF1) gene and blood serum IGF1 concentration in Hanwoo cattle.
The association of IGF1, GH, and PIT1 (show POU1F1 ELISA Kits) markers with growth and reproductive traits were assessed.
These findings strongly support the concept that IGF-1 upregulates LHR (show LHCGR ELISA Kits) expression in granulosa cells and that IGF-1 is required for determining which follicle becomes dominant and acquires ovulatory capacity.
Insulin (show INS ELISA Kits)-induced glucose uptake in lactating bovine mammary epithelial cells may involve the phosphatidylinositide 3-kinase- but not mitogen-activated protein kinase (show MAPK1 ELISA Kits)-mediated signaling pathways.
Data show that individuals with insulin-like growth factor I (IGF-1) allele C had a significantly higher performance in production traits.
Data suggest that metabolism of IGF1, IGF2, and IGFBP3 (insulin-like growth factor binding protein-3 (show IGFBP3 ELISA Kits)) can be altered by dietary modifications (here, long-term caloric restriction in Welsh Pony mares).
The laminar cell types expressing insulin receptor (show INSR ELISA Kits) and/or insulin-like growth factor-1 receptor (show IGF1R ELISA Kits) and the effect of dietary carbohydrates on their expression are reported.
Increased expression of IGF-1 in female equine embryos. Sex-related influences on expression of the IGF system are probably related to a gradual X chromosome inactivation.
Somatomedin (IGF-I) is localized in equine spermatogenic and Leydig cells, and IGF-I receptor (show IGF1R ELISA Kits) is present in spermatogonia, spermatocytes and Leydig cells.
Hsp90 (show HSP90AB1 ELISA Kits) inhibitor geldanamycin is used to assess age-related responses with IGF1 stimulation of chondrocytes.
Local IGF-1 might play a role in the lesion- and deafness-induced plasticity in FC and at AN/FC synapse following chronic kanamycin-induced deafness.
These results suggest the significant influence of the IGF1 gene on prolificacy in goats and identified SNPs would benefit the selection of prolific animals in future breeding programs.
The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Several transcript variants encoding different isoforms have been found for this gene.
, insulin-like growth factor 1
, insulin-like growth factor I
, insulin-like growth factor IA
, insulin-like growth factor IB
, mechano growth factor
, somatomedin C
, insulin-like growth factor-1
, Insulin-like growth factor I
, class 1 insulin-like growth factor I preproprotein
, insulin growth factor-1
, insulin like growth factor 1
, insulin-like growth factor I (somatomedin C)
, insulin-like growth factor I variant 1
, insulin like growth factor-1
, insulin-like growth factor-I
, insulin-like growth factor 1 (somatomedin C)
, insulin like growth factor 1 S homeolog
, insulin-like growth factor I-A