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Browse our IGF1R (IGF1R) ELISA Kits

Full name:
Insulin-Like Growth Factor 1 Receptor ELISA Kits (IGF1R)
On www.antibodies-online.com are 38 Insulin-Like Growth Factor 1 Receptor (IGF1R) ELISA Kits from 13 different suppliers available. Additionally we are shipping IGF1R Antibodies (428) and IGF1R Proteins (40) and many more products for this protein. A total of 522 IGF1R products are currently listed.
Synonyms:
A330103N21Rik, CD221, D930020L01, DKFZp469I0618, hyft, IGF-1R, IGF1R, IGFIR, IGFIRC, IGFR, IGFR1, JTK13, xIGF-1R, xigf1r, xIGFR
list all ELISA KIts Gene Name GeneID UniProt
IGF1R 3480 P08069
IGF1R 25718 P24062
IGF1R 16001 Q60751

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Top referenced IGF1R ELISA Kits

  1. Human IGF1R ELISA Kit for Sandwich ELISA - ABIN417695 : Bahhnassy, Mohanad, Shaarawy, Ismail, El-Bastawisy, Ashmawy, Zekri et al.: Transforming growth factor-β, insulin-like growth factor I/insulin-like growth factor I receptor and vascular endothelial growth factor-A: prognostic and predictive markers in triple-negative and ... in Molecular medicine reports 2015 (PubMed)

More ELISA Kits for IGF1R Interaction Partners

Horse (Equine) Insulin-Like Growth Factor 1 Receptor (IGF1R) interaction partners

  1. This study evaluated the expression of IGF-1 (show IGF1 ELISA Kits) receptor, insulin receptor (show INSR ELISA Kits) AND IGF-1 (show IGF1 ELISA Kits) in the lammelar tissue of horses with insulin (show INS ELISA Kits)-induced hyperinsulinemia.

  2. The laminar cell types expressing insulin receptor (show INSR ELISA Kits) and/or insulin-like growth factor-1 receptor and the effect of dietary carbohydrates on their expression are reported.

  3. Somatomedin (IGF-I (show IGF1 ELISA Kits)) is localized in equine spermatogenic and Leydig cells, and IGF-I receptor is present in spermatogonia, spermatocytes and Leydig cells.[IGF-I receptor]

Human Insulin-Like Growth Factor 1 Receptor (IGF1R) interaction partners

  1. miR223 may regulate the acquired resistance of PC9 (show PCSK9 ELISA Kits)/ER cells to erlotinib by targeting the IGF-1R/Akt (show AKT1 ELISA Kits)/S6 signaling pathway.

  2. decreasing IGF-1R mRNA and protein expression in NCI H295R cells can partially inhibit adrenal tumor cell growth in vitro.

  3. High IGF1R expression is associated with gastric cancer.

  4. IGF2R (show IGF2R ELISA Kits) plays a minor role in regulating the activity of IGF1R under a variety of conditions and that due to their high expression levels, IGFBPs are the dominant mechanism to regulating IGF network activation

  5. methylation of IGF-1 (show IGF1 ELISA Kits), IGF1R, IGFBP3 (show IGFBP3 ELISA Kits), and IGF-1 (show IGF1 ELISA Kits) + IGF1R + IGFBP3 (show IGFBP3 ELISA Kits) was closely linked with the occurrence of EC and patients' clinicopathological features. Besides, the methylation status of the target genes and the expressions of IGF-1 (show IGF1 ELISA Kits) and IGF-1R protein were independent factors of EC prognosis, which could provide a direction for the prognosis and treatment of EC.

  6. Positive correlations indicated probable cross-talk between the IGF-IR-mediated and adiponectin (show ADIPOQ ELISA Kits)-mediated signaling pathways.

  7. IGF1R is a direct target of miR (show MLXIP ELISA Kits)-494 in epithelial ovarian carcinoma cells. miR (show MLXIP ELISA Kits)-494 overexpression inhibited IGF1R expression and its downstream signal protein (show KLK7 ELISA Kits) expression. IGF1R downregulation has similar effects to miR (show MLXIP ELISA Kits)-494 overexpression on EOC cells, and overexpression of IGF1R effectively rescued the inhibition of overexpressed miR (show MLXIP ELISA Kits)-494 in EOC cells. miR (show MLXIP ELISA Kits)-494 directly binds the IGF1R 3'-UTR (show UTS2R ELISA Kits).

  8. identification of IGF-1R in odontogenic myxoma is shared with numerous tumours and indicates the ability of these tumour cells to respond to growth factors

  9. NANOG (show NANOG ELISA Kits) was regulated by extracellular IGF signaling pathway via STAT3 (show STAT3 ELISA Kits) phosphorylation in colorectal cancer (CRC (show CALR ELISA Kits)). This coincides with that IGF receptor IGF-1R is often increasing expressed in malignant metastasis colon cancer. Taken together, our data define the crucial functions of IGF/STAT3 (show STAT3 ELISA Kits)/NANOG (show NANOG ELISA Kits)/Slug (show SNAI2 ELISA Kits) signaling axis in the progression of CRC (show CALR ELISA Kits)

  10. This study suggests IGF1R as a potential biomarker of improved clinical outcome in HR+ve breast cancer patients treated with exemestane. Adding metformin to exemestane treatment may add to this effect

Pig (Porcine) Insulin-Like Growth Factor 1 Receptor (IGF1R) interaction partners

  1. IGF-I (show IGF1 ELISA Kits), IGF-II, and IGFBP-3 (show IGFBP3 ELISA Kits) mRNA were positively correlated with IGF-IR from 50E to 180D, suggesting that the expression of IGF-system genes exhibits specific developmental patterns in the skeletal muscle tissues.

  2. IL-1beta (show IL1B ELISA Kits) impaired the actions of IGF-I (show IGF1 ELISA Kits) at a point distal to the IGF receptor

  3. IGF-1R is expressed in porcine somatostatin (show SST ELISA Kits)-containing islet D-cells

  4. This study suggests an association between the affinity of insulin (show INS ELISA Kits) receptors and number of IGF-1 (show IGF1 ELISA Kits) receptors with placental and/or fetal growth.

  5. mRNA expression of IGF-I receptor

Cow (Bovine) Insulin-Like Growth Factor 1 Receptor (IGF1R) interaction partners

  1. A total of 1169 cows of 4 pure breeds (Polish Holstein Friesian, Montbeliarde, Jersey and Holstein Friesian) were genotyped. The T (IGF1R/e2/MspI) and G (IGF1R/e2/TaqI) alleles were found to be prevalent. 3 combinations of genotypes (TT/GG, TT/AG and CT/GG) were associated with the highest productivity (milk, protein and fat yields) among the breeds studied, as opposed to individuals carrying the worst CC/AA combination.

  2. study determined IGFR1 and PAPP-A (show PAPPA ELISA Kits) expression both in follicles at different stages of development and in ovarian cysts; data indicate that animals with cystic ovarian disease (COD (show SNRPB ELISA Kits)) have an altered regulation of the IGF system in the ovary and thus allow postulating IGFR1 expression and PAPP-A (show PAPPA ELISA Kits) secretion as a modulator of IGF1 (show IGF1 ELISA Kits) in cattle with COD (show SNRPB ELISA Kits)

  3. Results of the present study showed, for the first time, that the polymorphism in IGF1R is associated with superovulation traits, and indicated that the IGFIR gene can be used as a potential marker for donor selection.

  4. two SNPs in the coding region of the insulin-like growth factor 1 receptor gene may have a role in growth of Angus cattle

  5. insulin (show INS ELISA Kits)-like growth factor (IGF) receptor glycosylation is critical to the maintenance of vascular smooth muscle phenotype in the presence of factors promoting osteogenic differentiation and mineralization

  6. The objective of this study was to estimate the allele and genotype frequencies of the IGF-IR/TaqI, m-calpain (show CAPN2 ELISA Kits)/HhaI, and UCP-3 (show UCP3 ELISA Kits)/BglI polymorphisms and to determine association between these polymorphisms and growth traits in Chinese indigenous cattle breed.

  7. Data describes the long-term changes to skeletal muscle growth and IGF1 (show IGF1 ELISA Kits), 2, 1R, and 2R mRNA expression in progeny after exposure to high and low levels of maternal nutrient intake during the first two trimesters of gestation in the bovine.

  8. Results do not support the premise that increased apoptosis associated with high levels of IGF1 (show IGF1 ELISA Kits) is mediated via downregulation of the IGF1R as previously found in preimplantation mouse embryos.

  9. IGF-I (show IGF1 ELISA Kits) down-regulated functional IGF-I receptor via GSK-3beta inhibition and mTOR (show FRAP1 ELISA Kits) activation; constitutive activity of GSK-3beta maintained IGF-I receptor level in nonstimulated cells.

  10. IGF-1 (show IGF1 ELISA Kits) and IGF-1r gene polymorphisms in East Anatolian Red and South Anatolian Red cattle breeds.

Mouse (Murine) Insulin-Like Growth Factor 1 Receptor (IGF1R) interaction partners

  1. Suggest that overexpression of IGF-IR or IRA (show INSR ELISA Kits) isoform, as homodimers or as part of IRA (show INSR ELISA Kits)/IGF-IR hybrid receptors, confers a stronger migratory capability to vascular smooth muscle cells and might occur in early stages of atherosclerotic process.

  2. Macrophage IGF1R signaling suppresses macrophage and foam cell accumulation in lesions and reduces plaque vulnerability, providing a novel mechanism whereby IGF-1 (show IGF1 ELISA Kits) exerts antiatherogenic effects in ApoE (show APOE ELISA Kits) knockout mice.

  3. study recognized the promotion of miR (show MLXIP ELISA Kits)-223 level by AGE-BSA treatment in osteoblast-like MC3T3-E1 cells. The promoted miR (show MLXIP ELISA Kits)-223 targeted IGF-1R and mediated the AGE-BSA-induced apoptosis in MC3T3-E1 cells.

  4. osterix (show SP7 ELISA Kits) is a downstream target of IGF1R in chondrocytes.

  5. NF-kappaB (show NFKB1 ELISA Kits)-miR (show MLXIP ELISA Kits)-195/497-Igf1r/Insr (show INSR ELISA Kits)-Ccnd2 (show CCND2 ELISA Kits)/Ccne1 (show CCNE1 ELISA Kits) plays important roles in myogenesis.

  6. this study, we have characterized epigenetic changes following pregnancy and found that Igf1r and other IGF family members are hypermethylated and downregulated.

  7. IGF1R signaling was necessary for DC-mediated T-ALL survival.

  8. mitochondria, activated by IGF-1R signaling, constitute a critical regulator of information processing in hippocampal neurons.

  9. IGF1R is involved in osteoblast differentiation during fracture repair and it plays an important role in coordinating chondrocyte, osteoclast, and endothelial responses that contribute to endochondral bone formation required for normal fracture repair

  10. ectopic down-regulation of IGF1R reversed the protective effect of miR (show MLXIP ELISA Kits)-100 down-regulation on H2O2-induced apoptosis, revealing that miR (show MLXIP ELISA Kits)-100 regulates cardiomyocyte apoptosis through the association of IGF1R.

IGF1R Antigen Profile

Antigen Summary

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.

Alternative names and synonyms associated with IGF1R

  • insulin-like growth factor 1 receptor (IGF1R) Elisa Kit
  • insulin-like growth factor 1 receptor (igf1r) Elisa Kit
  • insulin-like growth factor 1 receptor (Igf1r) Elisa Kit
  • insulin-like growth factor I receptor (Igf1r) Elisa Kit
  • A330103N21Rik Elisa Kit
  • CD221 Elisa Kit
  • D930020L01 Elisa Kit
  • DKFZp469I0618 Elisa Kit
  • hyft Elisa Kit
  • IGF-1R Elisa Kit
  • IGF1R Elisa Kit
  • IGFIR Elisa Kit
  • IGFIRC Elisa Kit
  • IGFR Elisa Kit
  • IGFR1 Elisa Kit
  • JTK13 Elisa Kit
  • xIGF-1R Elisa Kit
  • xigf1r Elisa Kit
  • xIGFR Elisa Kit

Protein level used designations for IGF1R

insulin-like growth factor 1 receptor , IGF-I receptor , insulin-like growth factor I receptor , soluble IGF1R variant 1 , soluble IGF1R variant 2 , insulin-like growth factor-1 receptor beta subunit , xIGF-1R , xIGFR , insulin-like growth factor receptor tyrosine kinase , insulin-like growth factor-I receptor , type 1 IGF receptor , tyrosine kinase , IGF-1 receptor , insulin-like growth factor 1 receptor beta subunit , insulin-like growth factor receptor 1 , insulin-like growth factor-1 receptor , receptor tyrosine kinase , line 186

GENE ID SPECIES
100055698 Equus caballus
453676 Pan troglodytes
100172156 Pongo abelii
100329112 Xenopus (Silurana) tropicalis
100020095 Monodelphis domestica
3480 Homo sapiens
25718 Rattus norvegicus
398022 Xenopus laevis
395889 Gallus gallus
397350 Sus scrofa
281848 Bos taurus
442951 Canis lupus familiaris
100734840 Cavia porcellus
16001 Mus musculus
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