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Browse our KIT Proteins (KIT)

Full name:
Mast/stem Cell Growth Factor Receptor Proteins (KIT)
On are 37 Mast/stem Cell Growth Factor Receptor (KIT) Proteins from 9 different suppliers available. Additionally we are shipping KIT Antibodies (1182) and KIT Kits (41) and many more products for this protein. A total of 1267 KIT products are currently listed.
Bs, c-kit, CD117, Fdc, Gsfsco1, Gsfsco5, Gsfsow3, MGF, PBT, SCFR, SCO1, SCO5, SOW3, Ssm, Tr-kit, W
list all proteins Gene Name GeneID UniProt
KIT 16590 P05532
KIT 3815 P10721

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KIT Proteins (KIT) by Origin

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More Proteins for KIT Interaction Partners

Mouse (Murine) Mast/stem Cell Growth Factor Receptor (KIT) interaction partners

  1. Kit inactivation within oocytes also led to premature ovarian failure, albeit via a contrasting phenotype. Despite normal initial complements of primordial follicles, oocytes remained dormant with arrested oocyte maturation. Foxo3 (show FOXO3 Proteins) protein localization in the nucleus versus cytoplasm explained both mutant phenotypes.

  2. sca-1 antibody reduces both CD34+/c-kit+ progenitor cell surge and vascular restenosis after endoluminal vascular injury in a murine model.

  3. These findings indicate the SCF (show KITLG Proteins)/Kit signaling insufficiency may contribute to the underdevelopment of ICCs and intestinal motility dysfunction upon hypoxia exposure.

  4. we identified important roles for the GATA-2 C-ZnF in bone marrow hematopoiesis via control of c-Kit expression and HSC/HSPC survival.

  5. IMC-G4 cells had an additional novel c-kit gene mutation of KIT-Tyr421Cys which is considered to induce neoplastic transformation of mouse mast cells

  6. gene deficiency does not play a role in the pathogenesis of lupus in B6lpr/lpr (show FAS Proteins) mice.

  7. suggests FGF-9 has the potential to attenuate vascular cell apoptosis, activate c-Kit progenitor cells, and enhance angiogenesis and neovascularization in C57BL/6 and db/db (show LEPR Proteins) mice leading to improved cardiac function.

  8. Bone marrow-derived CD117+ hematopoietic progenitor cells differentiate into thymic dendritic cells in the fetal thymus organ culture system in the presence of Flt3L (show FLT3LG Proteins).

  9. C-kit signaling has a role in proliferation and invasion of colorectal mucinous adenocarcinoma

  10. TAK1 and IKK2 are novel mediators of SCF-induced signaling and potential targets for c-Kit-driven diseases.

Human Mast/stem Cell Growth Factor Receptor (KIT) interaction partners

  1. EGFR expression was observed in 58% and c-KIT expression was seen in 30% of the cases [triple negative breast cancer]

  2. Canonical TGF-beta (show TGFB1 Proteins) and c-KIT signaling forms a positive, tumor-promoting feedback loop. Disruption of this loop restores TGF-beta (show TGFB1 Proteins) tumor suppressor function and provides the rationale for targeting the TGF-beta (show TGFB1 Proteins)/SCF (show KITLG Proteins) axis as a novel therapeutic strategy for Hepatocellular carcinoma.

  3. We conclude that c-KIT expression is a valuable predictor of prognosis and survival, especially in thick (>4 mm) vulvar melanomas

  4. BRAF (show BRAF Proteins) mutations are rare events in KIT/PDGFRA (show PDGFRA Proteins) wild-type gastrointestinal stromal tumors.

  5. Results revealed that Orai1-mediated store-operated Ca(2 (show CA2 Proteins)+) entry is critical for gastrointestinal stromal tumor cell proliferation via c-KIT and ERK (show EPHB2 Proteins) signaling pathway activation.

  6. C646 treatment attenuated ETV1 protein expression and inactivated KIT-dependent pathways. Taken together, the present study suggests that CBP/p300 may serve as novel antineoplastic targets and that use of the selective HAT inhibitor C646 is a promising antitumor strategy for Gastrointestinal stromal tumors.

  7. Of the 66 apocrine lesions, 62 (94 %) did not express C-KIT compared to 4/63 (6 %) of the normal glands

  8. analyzed biopsy specimens for the presence of BRAF (show BRAF Proteins) mutations in exon 15

  9. Combination of mutant-specific BRAF (show BRAF Proteins) and CD117 ICC with cytopathology may facilitate the PTC (show F9 Proteins)-risk stratification in thyroid FNAB specimens.

  10. Expression of c-kit was associated with poorer overall survival (p = 0.011), while ALDH1A1 (show ALDH1A1 Proteins) expression was associated with shorter recurrence-free survival (p = 0.036).

Pig (Porcine) Mast/stem Cell Growth Factor Receptor (KIT) interaction partners

  1. mRNA expression of c-kit and SCF was decreased in gallbladder tissues in the HCD group. Consistent with the findings of RT-PCR, a lower expression level of c-kit and SCF protein was also observed in HCD animals.

  2. Delayed enrichment for c-kit and inducing cardiac differentiation attenuated protective effects of BMSCs' transplantation in pig model of acute myocardial infarction.

  3. Pravastatin improves function in hibernating myocardium by mobilizing CD133+ and cKit+ bone marrow progenitor cells and promoting myocytes to reenter the growth phase of the cardiac cell cycle.

Cow (Bovine) Mast/stem Cell Growth Factor Receptor (KIT) interaction partners

  1. FGF7 (show FGF7 Proteins) may be an important regulator for oocyte growth and its action is mediated via the KIT/KITLG (show KITLG Proteins) signaling pathway.

KIT Protein Profile

Protein Summary

This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with KIT

  • kit oncogene (Kit)
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT)
  • Bs protein
  • c-kit protein
  • CD117 protein
  • Fdc protein
  • Gsfsco1 protein
  • Gsfsco5 protein
  • Gsfsow3 protein
  • MGF protein
  • PBT protein
  • SCFR protein
  • SCO1 protein
  • SCO5 protein
  • SOW3 protein
  • Ssm protein
  • Tr-kit protein
  • W protein

Protein level used designations for KIT

Dominant white spotting , SCFR , Steel Factor Receptor , belly-spot , c-kit proto-oncogene protein , dominant spotting , mast/stem cell growth factor receptor Kit , proto-oncogene c-Kit , proto-oncogene tyrosine-protein kinase Kit , spotted sterile male , tyrosine-protein kinase Kit , p145 c-kit , piebald trait protein , soluble KIT variant 1 , v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein , c-kit , c-KIT gene1 , receptor tyrosine kinase c-kit , c-kit receptor , mast cell growth factor receptor

16590 Mus musculus
3815 Homo sapiens
378783 Gallus gallus
403811 Canis lupus familiaris
396810 Sus scrofa
280832 Bos taurus
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