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Browse our KIT Proteins (KIT)

Full name:
Mast/stem Cell Growth Factor Receptor Proteins (KIT)
On www.antibodies-online.com are 31 Mast/stem Cell Growth Factor Receptor (KIT) Proteins from 4 different suppliers available. Additionally we are shipping KIT Antibodies (1080) and KIT Kits (15) and many more products for this protein. A total of 1129 KIT products are currently listed.
Synonyms:
Bs, c-kit, CD117, Fdc, Gsfsco1, Gsfsco5, Gsfsow3, MGF, PBT, SCFR, SCO1, SCO5, SOW3, Ssm, Tr-kit, W
list all proteins Gene Name GeneID UniProt
Mouse KIT KIT 16590 P05532
KIT 3815 P10721

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KIT Proteins (KIT) by Origin

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More Proteins for KIT Interaction Partners

Mouse (Murine) Mast/stem Cell Growth Factor Receptor (KIT) interaction partners

  1. IMC-G4 cells had an additional novel c-kit gene mutation of KIT-Tyr421Cys which is considered to induce neoplastic transformation of mouse mast cells

  2. gene deficiency does not play a role in the pathogenesis of lupus in B6lpr/lpr (show FAS Proteins) mice.

  3. suggests FGF-9 has the potential to attenuate vascular cell apoptosis, activate c-Kit progenitor cells, and enhance angiogenesis and neovascularization in C57BL/6 and db/db (show LEPR Proteins) mice leading to improved cardiac function.

  4. Bone marrow-derived CD117+ hematopoietic progenitor cells differentiate into thymic dendritic cells in the fetal thymus organ culture system in the presence of Flt3L (show FLT3LG Proteins).

  5. C-kit signaling has a role in proliferation and invasion of colorectal mucinous adenocarcinoma

  6. TAK1 and IKK2 are novel mediators of SCF-induced signaling and potential targets for c-Kit-driven diseases.

  7. Findings indicate that CD45 antigen(+) and c-Kit protein(+) hematopoietic cells were more abundant in muscle than in bone marrow between embryonic 14.5 and 17.5 days.

  8. c-kit(+) cells in the murine heart are endothelial cells and not cardiac stem cells.

  9. As SALL4A (show SALL4 Proteins) is known to impair ZBTB16 (show ZBTB16 Proteins)-mediated Kit repression [14], our study provides novel insights into the molecular mechanism by which ATRA could control KIT expression, and thereby the differentiation of Aal into A1 spermatogonia in vivo.

  10. Data show that PI3 kinase is an attractive therapeutic target in malignancies induced by proto-oncogene protein c-Kit mutations.

Human Mast/stem Cell Growth Factor Receptor (KIT) interaction partners

  1. Of the 105 malignant melanomass, 13 (10 Han and 3 Uyghur) were found to have mutations in KIT. Thus, the frequency of KIT mutations in Han patients was significantly higher than that in Uyghur patients.

  2. we retrospectively examined correlations between clinical outcomes and KIT/PDGFRA (show PDGFRA Proteins) mutational status in a subset of imatinib-resistant or -intolerant patients with stromal tumor participating in a worldwide, open-label treatment-use study

  3. Data characterized metastatic exon 11 mutant gastrointestinal stromal tumors (GIST) genetic susceptibility genes beyond kit proto-oncogene (show RAB1A Proteins) protein (KIT)/PDGF (show PDGFA Proteins) alpha receptor (PDGFRalpha) genotype.

  4. Our data support those recently published in a meta-analysis on 1487 patients proving that GISTs bearing KIT mutations have a significantly poorer prognosis than either PDGFRA (show PDGFRA Proteins) mutated or WT GISTs

  5. c-kit mutation in exon 17 appeared to be significantly different between endometrial carcinoma and normal endometrium. The pattern and frequency of the mutations was also shown to be different between tumors from different stages.

  6. Case Report: rectal gastrointestinal stromal tumor with kit and PDGFRA (show PDGFRA Proteins) mutations.

  7. The results of this study indicate that c-kit/KITL (show KITLG Proteins) signalling also occurs in the human ovary, as established in various animal models, and may involve previously unknown autocrine signalling

  8. C-kit signaling has a role in proliferation and invasion of colorectal mucinous adenocarcinoma

  9. The KIT and PDGFRB (show PDGFRB Proteins) mutations were predicted to be pathogenic using in silico analysis, whereas the ERBB2 (show ERBB2 Proteins) mutation was predicted to be benign...the patient was treated with pazopanib and achieved a partial response that lasted for 7.5 months

  10. Aberrant c-KIT and DOG-1 (show ANO1 Proteins) expressions in CRC (show CALR Proteins) are rare events, either in NMA (show BAMBI Proteins) or MA.

Pig (Porcine) Mast/stem Cell Growth Factor Receptor (KIT) interaction partners

  1. mRNA expression of c-kit and SCF was decreased in gallbladder tissues in the HCD group. Consistent with the findings of RT-PCR, a lower expression level of c-kit and SCF protein was also observed in HCD animals.

  2. Delayed enrichment for c-kit and inducing cardiac differentiation attenuated protective effects of BMSCs' transplantation in pig model of acute myocardial infarction.

  3. Pravastatin improves function in hibernating myocardium by mobilizing CD133+ and cKit+ bone marrow progenitor cells and promoting myocytes to reenter the growth phase of the cardiac cell cycle.

Cow (Bovine) Mast/stem Cell Growth Factor Receptor (KIT) interaction partners

  1. FGF7 (show FGF7 Proteins) may be an important regulator for oocyte growth and its action is mediated via the KIT/KITLG (show KITLG Proteins) signaling pathway.

KIT Protein Profile

Protein Summary

This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with KIT

  • kit oncogene (Kit)
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT)
  • Bs protein
  • c-kit protein
  • CD117 protein
  • Fdc protein
  • Gsfsco1 protein
  • Gsfsco5 protein
  • Gsfsow3 protein
  • MGF protein
  • PBT protein
  • SCFR protein
  • SCO1 protein
  • SCO5 protein
  • SOW3 protein
  • Ssm protein
  • Tr-kit protein
  • W protein

Protein level used designations for KIT

Dominant white spotting , SCFR , Steel Factor Receptor , belly-spot , c-kit proto-oncogene protein , dominant spotting , mast/stem cell growth factor receptor Kit , proto-oncogene c-Kit , proto-oncogene tyrosine-protein kinase Kit , spotted sterile male , tyrosine-protein kinase Kit , p145 c-kit , piebald trait protein , soluble KIT variant 1 , v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein , c-kit , c-KIT gene1 , receptor tyrosine kinase c-kit , c-kit receptor , mast cell growth factor receptor

GENE ID SPECIES
16590 Mus musculus
3815 Homo sapiens
378783 Gallus gallus
403811 Canis lupus familiaris
396810 Sus scrofa
280832 Bos taurus
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