KIT Protein (AA 26-205) (His tag)

Catalog No. ABIN7504933

Product Details

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Protein Type: Recombinant

Protein Characteristics: AA 26-205

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This KIT protein is labelled with His tag.

Sequence: Gln26-Arg205

Characteristics: A DNA sequence encoding the Human KIT/SCFR (P10721-1) (Gln26-Arg205) was expressed with a polyhistidine tag at the N-terminus.

Purity: >95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Alternative Name: KIT (KIT Products)

Synonyms: C-Kit Protein, CD117 Protein, PBT Protein, SCFR Protein, Bs Protein, Fdc Protein, Gsfsco1 Protein, Gsfsco5 Protein, Gsfsow3 Protein, SCO1 Protein, SCO5 Protein, SOW3 Protein, Ssm Protein, Tr-kit Protein, W Protein, c-KIT Protein, c-kit Protein, MGF Protein, KIT Protein, C-KIT Protein, kit Protein, receptor Protein, sparse Protein, Xkl-1 Protein, kit-a Protein, kit-b Protein, kl1-A Protein, krk1 Protein, pbt Protein, scfr Protein, KIT proto-oncogene receptor tyrosine kinase Protein, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a Protein, KIT proto-oncogene receptor tyrosine kinase S homeolog Protein, KIT Protein, Kit Protein, kita Protein, kit Protein, kit.S Protein

Background:

Background: This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonym: C Kit,c-Kit,c-Kit Ligand,CD117,Kit,Kit Ligand,KIT oncogene,KIT proto oncogene receptor tyrosine kinase,KIT,Mast cell growth factor receptor,Mast/stem cell growth factor receptor Kit,MGF,p145 c-kit,PBT,Piebald trait protein,Proto oncogene c Kit,Proto oncogene tyrosine protein kinase Kit,Proto-oncogene c-Kit,SCF Receptor,SCFR,soluble KIT variant 1,Steel Factor Receptor,Stem cell factor receptor,tyrosine protein kinase Kit,Tyrosine-protein kinase Kit,v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog,v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein,v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

Molecular Weight: 20.1 kDa

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity