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Browse our MET Proteins (MET)

Full name:
Met Proto-Oncogene Proteins (MET)
On are 50 Met Proto-Oncogene (MET) Proteins from 12 different suppliers available. Additionally we are shipping MET Antibodies (555) and MET Kits (62) and many more products for this protein. A total of 693 MET products are currently listed.
AI838057, AUTS9, c-met, HGF, Hgfr, Par4, RCCP2
list all proteins Gene Name GeneID UniProt
MET 4233 P08581
MET 17295  
MET 24553 P97523

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MET Proteins (MET) by Origin

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Top referenced MET Proteins

  1. Rat (Rattus) MET Protein expressed in Human Cells - ABIN2009011 : Bottaro, Rubin, Faletto, Chan, Kmiecik, Vande Woude, Aaronson: Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. in Science (New York, N.Y.) 1991 (PubMed)
    Show all 6 references for ABIN2009011

  2. Dog (Canine) MET Protein expressed in Human Cells - ABIN2008841 : Weidner, Di Cesare, Sachs, Brinkmann, Behrens, Birchmeier: Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis. in Nature 1996 (PubMed)
    Show all 6 references for ABIN2008841

  3. Cynomolgus MET Protein expressed in Human Cells - ABIN2010132 : Stephenson, Tronick, Aaronson: Isolation from BALB/c mouse cells of a structural polypeptide of a third endogenous type C virus. in Cell 1975 (PubMed)
    Show all 6 references for ABIN2010132

  4. Human MET Protein expressed in Baculovirus infected Insect Cells - ABIN2003243 : Birchmeier, Birchmeier, Gherardi, Vande Woude: Met, metastasis, motility and more. in Nature reviews. Molecular cell biology 2003 (PubMed)
    Show all 6 references for ABIN2003243

  5. Human MET Protein expressed in Human Cells - ABIN2003239 : Pennacchietti, Michieli, Galluzzo, Mazzone, Giordano, Comoglio: Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene. in Cancer cell 2003 (PubMed)
    Show all 6 references for ABIN2003239

  6. Mouse (Murine) MET Protein expressed in Human Cells - ABIN2008062 : Boccaccio, Comoglio: Invasive growth: a MET-driven genetic programme for cancer and stem cells. in Nature reviews. Cancer 2006 (PubMed)
    Show all 6 references for ABIN2008062

  7. Human MET Protein expressed in HEK-293 Cells - ABIN2180662 : Rubin, Chan, Bottaro, Burgess, Taylor, Cech, Hirschfield, Wong, Miki, Finch: A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor. in Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)

More Proteins for MET Interaction Partners

Human Met Proto-Oncogene (MET) interaction partners

  1. Data indicate that oncogene (show RAB1A Proteins) c-Met was a putative target of microRNA miR (show MLXIP Proteins)-139-5p.

  2. Study identified the G-quadruplex structure in MET promoter and showed its importance in binding to the Sp1 (show PSG1 Proteins) activator promoting tumor growth.

  3. Data show that silencing of fibroblast growth factor receptors FGFR1 or FGFR2 overcomes resistance to the proto-oncogene proteins c-met (MET) inhibitor.

  4. Data show that inhibition of ATP binding cassette subfamily B member 1 (ABCB1) might be a novel therapeutic strategy for non-small cell lung cancer (NSCLC) patients with acquired resistance to proto-oncogene proteins c-met (MET) inhibitors.

  5. Results indicate that proto-oncogene protein c-MET (MET) expression was significantly associated with MET amplification.

  6. Report the application of advanced quantitative fluorescence microscopy techniques to study changes in the oligomerization state of the RTK Met in response to stimulation by its endogenous ligand hepatocyte growth factor (show HGF Proteins).

  7. Results show that overexpression of c-MET and its phosphorylation with up-regulation of VEGFR1 (show FLT1 Proteins) are associated with chemo-resistance phenotype of colon cancer.

  8. High c-Met expression is associated with small cell hypercalcemic ovarian carcinoma.

  9. The findings suggest that the oncogenic activity of hepsin (show HPN Proteins) arises not only from elevated expression level but also from depletion of HAI-1 (show SPINT1 Proteins), events which together trigger gain-of-function activity impacting HGF (show HGF Proteins)/MET signalling and epithelial cohesion

  10. analysis of ARID1A, CDH1 (show CDH1 Proteins), cMET and PIK3CA (show PIK3CA Proteins) expression and target-related microRNA expression in gastric cancer

Mouse (Murine) Met Proto-Oncogene (MET) interaction partners

  1. Molecular and functional studies revealed that ectopic Met expression in limb mesenchyme does not alter HGF (show HGF Proteins) expression patterns and levels, but impairs HGF (show HGF Proteins) bioavailability

  2. miR-206 suppressed c-Met expression in gastric cancer and could function as a potent tumor suppressor in c-Met overexpressing tumors.

  3. Meg3 overexpression in insulinoma cells down-regulated the expression of the protooncogene c-met.

  4. our results support the concept of the acrosome as a lysosome-related organelle and provide evidence for the identification of MET as a tyrosine kinase receptor (show KDR Proteins) that may play a role in fertilization.

  5. We show that a subset of adult calcitonin gene-related peptide (CGRP (show CALCA Proteins))-expressing myenteric neurons produce MET, the receptor for hepatocyte growth factor (show HGF Proteins).

  6. HGF and c-met inhibition by means of a novel monoclonal neutralizing antibody inhibits tumor growth in prostate cancer cells and in mouse xenografts.

  7. facilitates T cell recruitment to the heart via CCR5 receptor by inducing autocrine CCR5 ligand release

  8. C-Met pathway is suggested to contribute to the lymphomagenesis in the MALT lymphoma after H. heilmannii infection.

  9. c-Met targeting enhances the effect of irradiation and chemical agents against malignant colon cells harboring a KRAS mutation.

  10. HGFR activation is regulated by integrin beta-1 (show ITGB1 Proteins). Decreased Itgb1 (show ITGB1 Proteins) leads to decreased HGFR activation.

Cow (Bovine) Met Proto-Oncogene (MET) interaction partners

  1. possible cooperative role of the EGF (show EGF Proteins) and HGF (show HGF Proteins) pathways and indicate that cross-talk between their respective receptors may modulate mammary gland development in the cow

MET Protein Profile

Protein Summary

The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with MET

  • met proto-oncogene (MET)
  • met proto-oncogene (Met)
  • met proto-oncogene (hepatocyte growth factor receptor) (MET)
  • AI838057 protein
  • AUTS9 protein
  • c-met protein
  • HGF protein
  • Hgfr protein
  • Par4 protein
  • RCCP2 protein

Protein level used designations for Met Proto-Oncogene Proteins (MET)

HGF receptor , HGF/SF receptor , SF receptor , hepatocyte growth factor receptor , met proto-oncogene tyrosine kinase , proto-oncogene c-Met , scatter factor receptor , tyrosine-protein kinase Met , c-Met , HGF receptor c-Met

4233 Homo sapiens
17295 Mus musculus
24553 Rattus norvegicus
403438 Canis lupus familiaris
280855 Bos taurus
654328 Sus scrofa
100126565 Oryctolagus cuniculus
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