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Browse our MET Proteins (MET)

Full name:
Met Proto-Oncogene Proteins (MET)
On www.antibodies-online.com are 50 Met Proto-Oncogene (MET) Proteins from 12 different suppliers available. Additionally we are shipping MET Antibodies (682) and MET Kits (56) and many more products for this protein. A total of 814 MET products are currently listed.
Synonyms:
AI838057, AUTS9, c-met, HGF, Hgfr, Par4, RCCP2
list all proteins Gene Name GeneID UniProt
MET 4233 P08581
MET 17295  
MET 24553 P97523

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MET Proteins (MET) by Origin

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Top referenced MET Proteins

  1. Human MET Protein expressed in Human Cells - ABIN2003239 : Bottaro, Rubin, Faletto, Chan, Kmiecik, Vande Woude, Aaronson: Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. in Science (New York, N.Y.) 1991 (PubMed)
    Show all 6 references for ABIN2003239

  2. Dog (Canine) MET Protein expressed in Human Cells - ABIN2008841 : Weidner, Di Cesare, Sachs, Brinkmann, Behrens, Birchmeier: Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis. in Nature 1996 (PubMed)
    Show all 6 references for ABIN2008841

  3. Mouse (Murine) MET Protein expressed in Human Cells - ABIN2008064 : Stephenson, Tronick, Aaronson: Isolation from BALB/c mouse cells of a structural polypeptide of a third endogenous type C virus. in Cell 1975 (PubMed)
    Show all 6 references for ABIN2008064

  4. Human MET Protein expressed in Baculovirus infected Insect Cells - ABIN2003243 : Birchmeier, Birchmeier, Gherardi, Vande Woude: Met, metastasis, motility and more. in Nature reviews. Molecular cell biology 2003 (PubMed)
    Show all 6 references for ABIN2003243

  5. Rat (Rattus) MET Protein expressed in Human Cells - ABIN2009011 : Pennacchietti, Michieli, Galluzzo, Mazzone, Giordano, Comoglio: Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene. in Cancer cell 2003 (PubMed)
    Show all 6 references for ABIN2009011

  6. Cynomolgus MET Protein expressed in Human Cells - ABIN2010132 : Boccaccio, Comoglio: Invasive growth: a MET-driven genetic programme for cancer and stem cells. in Nature reviews. Cancer 2006 (PubMed)
    Show all 6 references for ABIN2010132

  7. Human MET Protein expressed in HEK-293 Cells - ABIN2180662 : Rubin, Chan, Bottaro, Burgess, Taylor, Cech, Hirschfield, Wong, Miki, Finch: A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor. in Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)

More Proteins for MET Interaction Partners

Human Met Proto-Oncogene (MET) interaction partners

  1. c-MET-positive advanced gastric cancer patients had a poorer prognosis than c-MET-negative patients.

  2. HDAC5 promotes cellular proliferation through the upregulation of cMet, and may provide a novel therapeutic target for the treatment of patients with Wilms' tumor.

  3. Using cytokine array analysis, we were able to demonstrate that GSC1 cell growth is mediated through hepatocyte growth factor (HGF (show HGF Proteins))/c-MET signaling pathway which is activated exclusively by HGF (show HGF Proteins) secreted from gastric carcinoma mesenchymal stem cells.

  4. high expression of c-Met might predict TMZ chemotherapy resistance both for patients and in vitro. Based on these results, c-Met may be a useful biomarker for identifying patients who should be candidates for more aggressive therapies such as c-Met targeted medicine.

  5. Notably, other mutations including MET, APC (show APC Proteins), CDH1 (show CDH1 Proteins), and FBXW7 (show FBXW7 Proteins) were also identified in Taiwanese oral squamous cell carcinoma patients.

  6. Results detected significantly higher levels of MET in thyroid carcinoma (TC) and was found as a Mir-3666 target through its 3'UTR binding to promote TC cell proliferation.

  7. This study reveals that miR (show MLXIP Proteins)-433-c-MET/CREB1 (show CREB1 Proteins)-Akt (show AKT1 Proteins)/GSK-3beta/Snail (show SNAI1 Proteins) signaling is critical to EMT (show ITK Proteins) in bladder cancer.

  8. Studied the clinical implications of alterations in the c-MET pathway in patients undergoing pulmonary metastasectomy. Results found that mutations in the MET gene identified in 20 patients of our cohort by NGS failed to be of prognostic relevance.

  9. High expression of C-met is an independent risk factor for overall survival and disease-free survival in Cholangiocarcinoma.

  10. This study suggests that MACC1 (show MACC1 Proteins) is an independent prognostic factor in gastric adenocarcinoma and that the prognostic impact of MACC1 (show MACC1 Proteins) may be associated with MACC1 (show MACC1 Proteins) partners other than MET.

Mouse (Murine) Met Proto-Oncogene (MET) interaction partners

  1. study demonstrates that co-activation of AKT (show AKT1 Proteins) and c-Met induces hepatocellular carcinoma development that depends on the mTORC1/FASN (show FASN Proteins) pathway.

  2. Molecular and functional studies revealed that ectopic Met expression in limb mesenchyme does not alter HGF (show HGF Proteins) expression patterns and levels, but impairs HGF (show HGF Proteins) bioavailability

  3. miR-206 suppressed c-Met expression in gastric cancer and could function as a potent tumor suppressor in c-Met overexpressing tumors.

  4. Meg3 overexpression in insulinoma cells down-regulated the expression of the protooncogene c-met.

  5. our results support the concept of the acrosome as a lysosome-related organelle and provide evidence for the identification of MET as a tyrosine kinase receptor (show KDR Proteins) that may play a role in fertilization.

  6. We show that a subset of adult calcitonin gene-related peptide (CGRP (show CALCA Proteins))-expressing myenteric neurons produce MET, the receptor for hepatocyte growth factor (show HGF Proteins).

  7. HGF and c-met inhibition by means of a novel monoclonal neutralizing antibody inhibits tumor growth in prostate cancer cells and in mouse xenografts.

  8. facilitates T cell recruitment to the heart via CCR5 receptor by inducing autocrine CCR5 ligand release

  9. C-Met pathway is suggested to contribute to the lymphomagenesis in the MALT lymphoma after H. heilmannii infection.

  10. c-Met targeting enhances the effect of irradiation and chemical agents against malignant colon cells harboring a KRAS mutation.

Cow (Bovine) Met Proto-Oncogene (MET) interaction partners

  1. possible cooperative role of the EGF (show EGF Proteins) and HGF (show HGF Proteins) pathways and indicate that cross-talk between their respective receptors may modulate mammary gland development in the cow

MET Protein Profile

Protein Summary

The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with MET

  • met proto-oncogene (MET)
  • met proto-oncogene (Met)
  • met proto-oncogene (hepatocyte growth factor receptor) (MET)
  • AI838057 protein
  • AUTS9 protein
  • c-met protein
  • HGF protein
  • Hgfr protein
  • Par4 protein
  • RCCP2 protein

Protein level used designations for Met Proto-Oncogene Proteins (MET)

HGF receptor , HGF/SF receptor , SF receptor , hepatocyte growth factor receptor , met proto-oncogene tyrosine kinase , proto-oncogene c-Met , scatter factor receptor , tyrosine-protein kinase Met , c-Met , HGF receptor c-Met

GENE ID SPECIES
4233 Homo sapiens
17295 Mus musculus
24553 Rattus norvegicus
403438 Canis lupus familiaris
280855 Bos taurus
654328 Sus scrofa
100126565 Oryctolagus cuniculus
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