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Browse our MET Proteins (MET)

Full name:
Met Proto-Oncogene Proteins (MET)
On www.antibodies-online.com are 50 Met Proto-Oncogene (MET) Proteins from 12 different suppliers available. Additionally we are shipping MET Antibodies (684) and MET Kits (56) and many more products for this protein. A total of 816 MET products are currently listed.
Synonyms:
AI838057, AUTS9, c-met, HGF, Hgfr, Par4, RCCP2
list all proteins Gene Name GeneID UniProt
MET 4233 P08581
MET 17295  
MET 24553 P97523

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MET Proteins (MET) by Origin

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Top referenced MET Proteins

  1. Human MET Protein expressed in Human Cells - ABIN2003239 : Bottaro, Rubin, Faletto, Chan, Kmiecik, Vande Woude, Aaronson: Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. in Science (New York, N.Y.) 1991 (PubMed)
    Show all 6 references for ABIN2003239

  2. Dog (Canine) MET Protein expressed in Human Cells - ABIN2008841 : Weidner, Di Cesare, Sachs, Brinkmann, Behrens, Birchmeier: Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis. in Nature 1996 (PubMed)
    Show all 6 references for ABIN2008841

  3. Mouse (Murine) MET Protein expressed in Human Cells - ABIN2008062 : Stephenson, Tronick, Aaronson: Isolation from BALB/c mouse cells of a structural polypeptide of a third endogenous type C virus. in Cell 1975 (PubMed)
    Show all 6 references for ABIN2008062

  4. Human MET Protein expressed in Baculovirus infected Insect Cells - ABIN2003243 : Birchmeier, Birchmeier, Gherardi, Vande Woude: Met, metastasis, motility and more. in Nature reviews. Molecular cell biology 2003 (PubMed)
    Show all 6 references for ABIN2003243

  5. Rat (Rattus) MET Protein expressed in Human Cells - ABIN2009011 : Pennacchietti, Michieli, Galluzzo, Mazzone, Giordano, Comoglio: Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene. in Cancer cell 2003 (PubMed)
    Show all 6 references for ABIN2009011

  6. Cynomolgus MET Protein expressed in Human Cells - ABIN2010132 : Boccaccio, Comoglio: Invasive growth: a MET-driven genetic programme for cancer and stem cells. in Nature reviews. Cancer 2006 (PubMed)
    Show all 6 references for ABIN2010132

  7. Human MET Protein expressed in HEK-293 Cells - ABIN2180662 : Rubin, Chan, Bottaro, Burgess, Taylor, Cech, Hirschfield, Wong, Miki, Finch: A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor. in Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)

More Proteins for MET Interaction Partners

Human Met Proto-Oncogene (MET) interaction partners

  1. PIK3CA (show PIK3CA Proteins) and MET may play an important role in oncogenesis of certain specific subtypes of head and neck cancer

  2. The expression of c-Met and ERbeta were significantly related to the basal-like phenotype in triple-negative breast cancer, however, high c-Met expression and basal-like phenotypes did not show a direct correlation with poor prognosis

  3. HGF (show HGF Proteins)-induced FRA1 (show FOSL1 Proteins) activation is associated with the fibrosis-dependent development of Hepatocellular Carcinoma.

  4. NEAT1 functions a molecular sponge for miR-449b-5p and leads to the upregulation of c-Met. This regulation menchaism promotes glioma pathogenesis and may provide a potential target for the prognosis and treatment of glioma.

  5. activation of HGF/c-MET signaling in an autocrine fashion leads to an aggressive phenotype in SS and targeting of this signaling exerts superior antitumor effects on c-MET-activated SS. HGF/c-MET expression status is a potential biomarker for identification of SS patients with a worse prognosis who can benefit from c-MET inhibitors.

  6. both EGCG and miR-1 mimic inhibited c-MET expression, and combination treatment with EGCG and c-MET inhibitor (crizotinib) had enhanced inhibitory effects on the growth of MG-63 and U-2OS cells. Taken together, these results suggest that EGCG has an anticancer effect on OS cells, at least partially, through regulating miR-1/c-MET interaction.

  7. This study showed that c-Met expression was not associated with survival outcomes in extrahepatic bile duct cancer patients undergoing curative resection followed by adjuvant chemoradiotherapy

  8. Our data indicate that over-expression of MET and KIT in primary adult soft tissue sarcomas samples and its derived cell lines is associated with miR (show MLXIP Proteins)-152 down-regulation

  9. complete loss of one or both MET and RON (show MST1R Proteins), as well as their overexpression, is a poor prognostic factor in patients with extrahepatic cholangiocarcinoma, probably due to the high rate of lymph-node metastasis

  10. c-MET-positive advanced gastric cancer patients had a poorer prognosis than c-MET-negative patients.

Mouse (Murine) Met Proto-Oncogene (MET) interaction partners

  1. study demonstrates that co-activation of AKT (show AKT1 Proteins) and c-Met induces hepatocellular carcinoma development that depends on the mTORC1/FASN (show FASN Proteins) pathway.

  2. Molecular and functional studies revealed that ectopic Met expression in limb mesenchyme does not alter HGF (show HGF Proteins) expression patterns and levels, but impairs HGF (show HGF Proteins) bioavailability

  3. miR-206 suppressed c-Met expression in gastric cancer and could function as a potent tumor suppressor in c-Met overexpressing tumors.

  4. Meg3 overexpression in insulinoma cells down-regulated the expression of the protooncogene c-met.

  5. our results support the concept of the acrosome as a lysosome-related organelle and provide evidence for the identification of MET as a tyrosine kinase receptor (show KDR Proteins) that may play a role in fertilization.

  6. We show that a subset of adult calcitonin gene-related peptide (CGRP (show CALCA Proteins))-expressing myenteric neurons produce MET, the receptor for hepatocyte growth factor (show HGF Proteins).

  7. HGF and c-met inhibition by means of a novel monoclonal neutralizing antibody inhibits tumor growth in prostate cancer cells and in mouse xenografts.

  8. facilitates T cell recruitment to the heart via CCR5 receptor by inducing autocrine CCR5 ligand release

  9. C-Met pathway is suggested to contribute to the lymphomagenesis in the MALT lymphoma after H. heilmannii infection.

  10. c-Met targeting enhances the effect of irradiation and chemical agents against malignant colon cells harboring a KRAS mutation.

Cow (Bovine) Met Proto-Oncogene (MET) interaction partners

  1. possible cooperative role of the EGF (show EGF Proteins) and HGF (show HGF Proteins) pathways and indicate that cross-talk between their respective receptors may modulate mammary gland development in the cow

MET Protein Profile

Protein Summary

The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with MET

  • met proto-oncogene (MET)
  • met proto-oncogene (Met)
  • met proto-oncogene (hepatocyte growth factor receptor) (MET)
  • AI838057 protein
  • AUTS9 protein
  • c-met protein
  • HGF protein
  • Hgfr protein
  • Par4 protein
  • RCCP2 protein

Protein level used designations for Met Proto-Oncogene Proteins (MET)

HGF receptor , HGF/SF receptor , SF receptor , hepatocyte growth factor receptor , met proto-oncogene tyrosine kinase , proto-oncogene c-Met , scatter factor receptor , tyrosine-protein kinase Met , c-Met , HGF receptor c-Met

GENE ID SPECIES
4233 Homo sapiens
17295 Mus musculus
24553 Rattus norvegicus
403438 Canis lupus familiaris
280855 Bos taurus
654328 Sus scrofa
100126565 Oryctolagus cuniculus
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