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Browse our MET Proteins (MET)

Full name:
Met Proto-Oncogene Proteins (MET)
On www.antibodies-online.com are 51 Met Proto-Oncogene (MET) Proteins from 13 different suppliers available. Additionally we are shipping MET Antibodies (702) and MET Kits (59) and many more products for this protein. A total of 838 MET products are currently listed.
Synonyms:
AI838057, AUTS9, c-met, HGF, Hgfr, Par4, RCCP2
list all proteins Gene Name GeneID UniProt
MET 4233 P08581
MET 17295  
MET 24553 P97523

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MET Proteins (MET) by Origin

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Top referenced MET Proteins

  1. Rat (Rattus) MET Primary Antibody for - ABIN2009011 : Bottaro, Rubin, Faletto, Chan, Kmiecik, Vande Woude, Aaronson: Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. in Science (New York, N.Y.) 1991 (PubMed)
    Show all 6 references for ABIN2009011

  2. Dog (Canine) MET Primary Antibody for - ABIN2008841 : Weidner, Di Cesare, Sachs, Brinkmann, Behrens, Birchmeier: Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis. in Nature 1996 (PubMed)
    Show all 6 references for ABIN2008841

  3. Mouse (Murine) MET Primary Antibody for - ABIN2008064 : Stephenson, Tronick, Aaronson: Isolation from BALB/c mouse cells of a structural polypeptide of a third endogenous type C virus. in Cell 1975 (PubMed)
    Show all 6 references for ABIN2008064

  4. Human MET Primary Antibody for - ABIN2003243 : Birchmeier, Birchmeier, Gherardi, Vande Woude: Met, metastasis, motility and more. in Nature reviews. Molecular cell biology 2003 (PubMed)
    Show all 6 references for ABIN2003243

  5. Human MET Primary Antibody for - ABIN2003239 : Pennacchietti, Michieli, Galluzzo, Mazzone, Giordano, Comoglio: Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene. in Cancer cell 2003 (PubMed)
    Show all 6 references for ABIN2003239

  6. Cynomolgus MET Primary Antibody for - ABIN2010132 : Boccaccio, Comoglio: Invasive growth: a MET-driven genetic programme for cancer and stem cells. in Nature reviews. Cancer 2006 (PubMed)
    Show all 6 references for ABIN2010132

  7. Human MET Primary Antibody for - ABIN2180662 : Rubin, Chan, Bottaro, Burgess, Taylor, Cech, Hirschfield, Wong, Miki, Finch: A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor. in Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)

More Proteins for MET Interaction Partners

Human Met Proto-Oncogene (MET) interaction partners

  1. Study provides evidence that AXL (show AXL Proteins) and MET are associated with cell proliferation and metastasis in lung cancer, and the crosstalk between these receptors affects tumor progression.

  2. overexpression of HGF resulted in resistance to c-MET tyrosine kinase inhibitors through an autocrine manner in gastric cancer cells

  3. CMET overexpression and CMET amplification are commonly found in non-small cell lung cancer (NSCLC) brain metastases and may represent a promising therapeutic target.

  4. Study shows that MET was directly regulated by miR (show MLXIP Proteins)-23b and miR (show MLXIP Proteins)-27b. Moreover, downregulating the MET gene by use of siRNA significantly inhibited cell migration and invasion by oral squamous cell carcinoma cells.

  5. Activation of the HGF (show HGF Proteins)-mediated MET pathway is involved in escape to selective VEGFR (show KDR Proteins) inhibition in neuroblastoma (show ARHGEF16 Proteins) suggesting combined inhibition of MET and VEGFR (show KDR Proteins) signaling to reduce secondary resistance and enhanced invasiveness.

  6. miR (show MLXIP Proteins)-27b was frequently downregulated in NSCLC tissues and cell lines and could inhibit the malignant phenotypes of NSCLC cells by directly targeting the MET oncogene (show RAB1A Proteins). The identification of miR (show MLXIP Proteins)-27b-mediated novel signaling pathways may help reveal the molecular mechanism underlying the development and malignant progression of this disease.

  7. Therefore, our findings suggested miR (show MLXIP Proteins)-34a could modulate human gastric cancer(GC) cell Cisplatin sensitivity by regulation of cell proliferation and apoptosis via targeting MET, potentially benefiting human GC treatment in the future.

  8. miR1 (show FSD1 Proteins) expression inversely correlated with MET, cyclin D1 (show CCND1 Proteins) and CDK4 (show CDK4 Proteins) expression in esophageal squamous cell carcinoma cells.

  9. c-Met is expressed in malignant pleural mesothelioma, with significant differences in expression among histologic subtypes

  10. High c-MET expression is associated with esophageal squamous cell carcinoma.

Mouse (Murine) Met Proto-Oncogene (MET) interaction partners

  1. study demonstrates that co-activation of AKT (show AKT1 Proteins) and c-Met induces hepatocellular carcinoma development that depends on the mTORC1/FASN (show FASN Proteins) pathway.

  2. Molecular and functional studies revealed that ectopic Met expression in limb mesenchyme does not alter HGF (show HGF Proteins) expression patterns and levels, but impairs HGF (show HGF Proteins) bioavailability

  3. miR-206 suppressed c-Met expression in gastric cancer and could function as a potent tumor suppressor in c-Met overexpressing tumors.

  4. Meg3 overexpression in insulinoma cells down-regulated the expression of the protooncogene c-met.

  5. our results support the concept of the acrosome as a lysosome-related organelle and provide evidence for the identification of MET as a tyrosine kinase receptor (show KDR Proteins) that may play a role in fertilization.

  6. We show that a subset of adult calcitonin gene-related peptide (CGRP (show CALCA Proteins))-expressing myenteric neurons produce MET, the receptor for hepatocyte growth factor (show HGF Proteins).

  7. HGF and c-met inhibition by means of a novel monoclonal neutralizing antibody inhibits tumor growth in prostate cancer cells and in mouse xenografts.

  8. facilitates T cell recruitment to the heart via CCR5 receptor by inducing autocrine CCR5 ligand release

  9. C-Met pathway is suggested to contribute to the lymphomagenesis in the MALT lymphoma after H. heilmannii infection.

  10. c-Met targeting enhances the effect of irradiation and chemical agents against malignant colon cells harboring a KRAS mutation.

Cow (Bovine) Met Proto-Oncogene (MET) interaction partners

  1. possible cooperative role of the EGF (show EGF Proteins) and HGF (show HGF Proteins) pathways and indicate that cross-talk between their respective receptors may modulate mammary gland development in the cow

MET Protein Profile

Protein Summary

The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with MET

  • met proto-oncogene (MET)
  • met proto-oncogene (Met)
  • met proto-oncogene (hepatocyte growth factor receptor) (MET)
  • AI838057 protein
  • AUTS9 protein
  • c-met protein
  • HGF protein
  • Hgfr protein
  • Par4 protein
  • RCCP2 protein

Protein level used designations for Met Proto-Oncogene Proteins (MET)

HGF receptor , HGF/SF receptor , SF receptor , hepatocyte growth factor receptor , met proto-oncogene tyrosine kinase , proto-oncogene c-Met , scatter factor receptor , tyrosine-protein kinase Met , c-Met , HGF receptor c-Met

GENE ID SPECIES
4233 Homo sapiens
17295 Mus musculus
24553 Rattus norvegicus
403438 Canis lupus familiaris
280855 Bos taurus
654328 Sus scrofa
100126565 Oryctolagus cuniculus
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