Browse our MME Proteins (MME)

On are 39 Membrane Metallo-Endopeptidase (MME) Proteins from 13 different suppliers available. Additionally we are shipping MME Antibodies (642) and MME Kits (43) and many more products for this protein. A total of 747 MME products are currently listed.
6030454K05Rik, AV378681, C85356, CAK, CALLA, CD10, CD167, DDR, EDDR1, HGK2, MCK10, MME, Mmel, Nep, NTRK4, PTK3, PTK3A, RTK6, SFE, TRKE
list all proteins Gene Name GeneID UniProt
MME 780 Q08345
MME 17381 P34960
MME 24590 P07861

MME Proteins (MME) by Origin

More Proteins for MME Interaction Partners

Pig (Porcine) Membrane Metallo-Endopeptidase (MME) interaction partners

  1. Neutral endopeptidase 24.11 and DPP-IV (show DPP4 Proteins) is superior to DPP-IV (show DPP4 Proteins) inhibition alone in preserving intact GLP-1 (show GCG Proteins), which implies possibility that the combination has therapeutic potential.

  2. This study provides evidence that NEP 24.11 is an important mediator of the degradation of both endogenous and exogenous glucagon (show GCG Proteins) in vivo.

Human Membrane Metallo-Endopeptidase (MME) interaction partners

  1. This study suggested that DDR1 (show DDR1 Proteins) and DDR2 (show DDR2 Proteins) knockdown alters brain immunity and significantly reduces the level of triggering receptor expressed on myeloid cells (TREM)-2 (show TREM2 Proteins) and microglia.

  2. Isoform b of DDR1 (show DDR1 Proteins) is responsible for collagen I-induced up-regulation of N-cadherin (show CDH2 Proteins) and tyrosine 513 of DDR1b is necessary.

  3. CD10 is a necessary component conferring the L1 effects in CRC (show CALR Proteins) cells. The identification of gene expression patterns of L1-domain-specific point mutations may provide novel markers and targets for interfering with L1-mediated CRC (show CALR Proteins) progression.

  4. High CD10 expression is associated with lymphoma in Waldeyer ring.

  5. Rare Variants in MME, Encoding Metalloprotease (show ADAM8 PLURAL_@34830@) Neprilysin, Are Linked to Late-Onset Autosomal-Dominant Axonal Polyneuropathies

  6. Reduced DDR1 (show DDR1 Proteins) expression may be implicated in impaired melanocyte adhesion process involved in vitiligo (show MITF Proteins) pathogenesis

  7. CD10 down expression in follicular lymphoma correlates with gastrointestinal lesion involving the stomach and large intestine

  8. data demonstrate that TGF-beta1 (show TGFB1 Proteins) favors linear invadosome formation through the expressions of both the inducers, such as collagen and LOXL2 (show LOXL2 Proteins), and the components such as DDR1 (show DDR1 Proteins) and MT1-MMP (show MMP14 Proteins) of linear invadosomes in cancer cells. Meanwhile, our data uncover a new TGF-beta1 (show TGFB1 Proteins)-dependent regulation of DDR1 (show DDR1 Proteins) expression.

  9. DDR1 (show DDR1 Proteins) overexpression promoted GC cell proliferation (p < 0.05), migration (p < 0.01), and invasion (p < 0.01), and accelerated the growth (p < 0.05) as well as the microvessel formation (p < 0.01) of transplantation tumor in nude mice.

  10. Our results suggest that DDR1 (show DDR1 Proteins) is both a prognostic marker for renal clear cell carcinoma and a potential functional target for therapy

Mouse (Murine) Membrane Metallo-Endopeptidase (MME) interaction partners

  1. Mmp12 (show MMP12 Proteins) is expressed early following corneal epithelial injury with highest expression levels at 8 h after injury and lower expression levels at 4 and 8 days after injury. We investigated whether MMP12 (show MMP12 Proteins) has an effect on the rate of epithelial repair and cell migration using in vivo and in vitro scratch assays performed on WT and Mmp12 (show MMP12 Proteins)(-/-) mice

  2. Rare Variants in MME, Encoding Metalloprotease (show ADAMTS7 PLURAL_@34830@) Neprilysin, Are Linked to Late-Onset Autosomal-Dominant Axonal Polyneuropathies

  3. MMP-12 (show MMP12 Proteins) produced by macrophages infiltrating into glomeruli contributed to the degradation of collagen type IV (show COL4 Proteins) and fibronectin (show FN1 Proteins).

  4. MMP12 (show MMP12 Proteins) causes arterial stiffening in mice and suggest that it functions similarly in humans.

  5. These results suggest that MMP-12 (show MMP12 Proteins) production during emphysema exacerbation results in increased mortality and disease progression.

  6. study found significant increases of MMP-3 (show MMP3 Proteins) and MMP-12 (show MMP12 Proteins) mRNA levels and MMP12 (show MMP12 Proteins) zymographic activities in response to Cryptococcus neoformans infection but not C. gattii infection

  7. The results suggest that pulmonary C fiber involvement in long-term airway inflammation and airway hyperresponsiveness occurred at least partially via modulating MMP-12 (show MMP12 Proteins), and the activation of PAR2 (show F2RL1 Proteins) might be related to MMP-12 (show MMP12 Proteins) production.

  8. MMP-12 (show MMP12 Proteins) up-regulation mediated by SARM (show SARM1 Proteins)-TRIF (show RNF138 Proteins) signaling pathway contributes to IFN-gamma (show IFNG Proteins)-independent airway inflammation and AHR (show AHR Proteins) post RSV infection in nude mice.

  9. MMP-12 (show MMP12 Proteins) and MMP-13 (show MMP13 Proteins) alter strain K infection in mice and play a role in inflammatory regulation by modulating cytokine levels.

  10. Amyloid beta (Abeta (show APP Proteins))-degrading effects of overexpressed neprilysin can block deleterious BACE1 (show BACE Proteins)-elevating mechanisms that accelerate Abeta (show APP Proteins) production

MME Protein Profile

Protein Summary

This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing.

Alternative names and synonyms associated with MME

  • membrane metallo-endopeptidase (MME)
  • discoidin domain receptor tyrosine kinase 1 (DDR1)
  • matrix metallopeptidase 12 (Mmp12)
  • membrane metallo endopeptidase (Mme)
  • membrane metallo-endopeptidase (Mme)
  • 6030454K05Rik protein
  • AV378681 protein
  • C85356 protein
  • CAK protein
  • CALLA protein
  • CD10 protein
  • CD167 protein
  • DDR protein
  • EDDR1 protein
  • HGK2 protein
  • MCK10 protein
  • MME protein
  • Mmel protein
  • Nep protein
  • NTRK4 protein
  • PTK3 protein
  • PTK3A protein
  • RTK6 protein
  • SFE protein
  • TRKE protein

Protein level used designations for MME

membrane metallo-endopeptidase , enkephalinase , neutral endopeptidase , membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase) , membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) , neprilysin , neprilysin-410 short isoform , CD167 antigen-like family member A , PTK3A protein tyrosine kinase 3A , cell adhesion kinase , epithelial discoidin domain-containing receptor 1 , mammary carcinoma kinase 10 , neuroepithelial tyrosine kinase , neurotrophic tyrosine kinase, receptor, type 4 , protein-tyrosine kinase RTK-6 , tyrosine kinase DDR , tyrosine-protein kinase CAK , MME , MMP-12 , macrophage elastase , macrophage metalloelastase , macrophage-metalloelastase , matrix metalloproteinase 12 , matrix metalloproteinase-12 , atriopeptidase , common acute lymphoblastic leukemia antigen , neutral endopeptidase 24.11 , skin fibroblast elastase , common acute lymphocytic leukemia antigen , membrane metallo-endopeptidase variant 1 , membrane metallo-endopeptidase variant 2 , membrane metallo endopeptidase , membrane metallo-endopeptidase (neutral endopeptidase/enkephalinase) , NEP

497058 Sus scrofa
425031 Gallus gallus
477120 Canis lupus familiaris
780 Homo sapiens
17381 Mus musculus
17380 Mus musculus
4311 Homo sapiens
24590 Rattus norvegicus
100511536 Sus scrofa
100009251 Oryctolagus cuniculus
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