You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our PDGFBB Proteins (PDGFBB)

Full name:
Platelet Derived Growth Factor BB Proteins (PDGFBB)
On www.antibodies-online.com are 69 Platelet Derived Growth Factor BB (PDGFBB) Proteins from 16 different suppliers available. Additionally we are shipping PDGFBB Kits (72) and PDGFBB Antibodies (48) and many more products for this protein. A total of 189 PDGFBB products are currently listed.
Synonyms:
c-sis, PDGF-2, PDGF2, SIS, SSV
list all proteins Gene Name GeneID UniProt
PDGFBB 5155 P01127
PDGFBB    
PDGFBB    

Show all synonyms

PDGFBB Proteins (PDGFBB) by Origin

Select your origin of interest

Top referenced PDGFBB Proteins

  1. Mouse (Murine) PDGFBB Protein expressed in Escherichia coli (E. coli) - ABIN2666565 : Risinger, Updike, Bullen, Tomasek, Howard: TGF-beta suppresses the upregulation of MMP-2 by vascular smooth muscle cells in response to PDGF-BB. in American journal of physiology. Cell physiology 2009 (PubMed)
    Show all 5 references for ABIN2666565

  2. Human PDGFBB Protein expressed in Escherichia coli (E. coli) - ABIN2667569 : Ustach, Kim: Platelet-derived growth factor D is activated by urokinase plasminogen activator in prostate carcinoma cells. in Molecular and cellular biology 2005 (PubMed)
    Show all 5 references for ABIN2667569

  3. Human PDGFBB Protein expressed in Escherichia coli (E. coli) - ABIN1589629 : Rezzola, Dal Monte, Belleri, Bugatti, Chiodelli, Corsini, Cammalleri, Cancarini, Morbidelli, Oreste, Bagnoli, Semeraro, Presta: Therapeutic Potential of Anti-Angiogenic Multitarget N,O-Sulfated E. Coli K5 Polysaccharide in Diabetic Retinopathy. in Diabetes 2015 (PubMed)

  4. Human PDGFBB Protein expressed in Escherichia coli (E. coli) - ABIN413706 : Tsuchida, Schneider, Pizani, Oliveira: Lead and aluminum bonding in Pb-AI metaphosphate glasses. in Inorganic chemistry 2008 (PubMed)

  5. Mouse (Murine) PDGFBB Protein expressed in Escherichia coli (E. coli) - ABIN413709 : Hamada, Gonda, Takeda, Sato, Watanabe, Yambe, Satomi, Ohuchi: In vivo imaging of the molecular distribution of the VEGF receptor during angiogenesis in a mouse model of ischemia. in Blood 2011 (PubMed)

More Proteins for PDGFBB Interaction Partners

Human Platelet Derived Growth Factor BB (PDGFBB) interaction partners

  1. Case Report: congenital atrophic dermatofibrosarcoma protuberans with COL1A1-PDGFB rearrangement.

  2. Loss of Nf2 (show NF2 Proteins) and Cdkn2a/b have synergistic effects with PDGF-B (show PDGFB Proteins) overexpression promoting meningioma malignant transformation.

  3. Human uPAR (show PLAUR Proteins) activation and its association with beta1-integrin are required for PDGF (show PDGFA Proteins)-AB-induced migration.

  4. Placental endothelial cell-derived PDGF (show PDGFA Proteins)-BB recruits human placental multipotent mesenchymal stromal cells involved in vascular development via PDGFR-beta (show PDGFRB Proteins)/STAT3 (show STAT3 Proteins) activation

  5. Suggest that PDGF-B (show PDGFB Proteins) signaling may play a role in endothelial and cardiomyocyte recovery from ischemia reperfusion injury after heart transplantation.

  6. Lessons from SLC20A2, PDGFB, and PDGFRB mutation carriers. Three causative genes have been identified: SLC20A2, PDGFRB and, recently, PDGFB, whose associated phenotype has not yet been extensively studied.

  7. loss-of-function mutations in PDGFB (show PDGFB Proteins) or PDGFRB (show PDGFRB Proteins) cause Primary Familial Brain Calcification.

  8. Three factor model revealed significant gene-gene interaction for PDGFB (show PDGFB Proteins) +286A>G, PDGFB (show PDGFB Proteins) +1135A>C and HER2 (show ERBB2 Proteins) Ile165Val SNPs with GBC. Protein-protein interaction showed significant association of PDGFB (show PDGFB Proteins) and HER2 (show ERBB2 Proteins) with EGFR (show EGFR Proteins) receptor signaling pathway.

  9. Regulation of Hyaluronan (HA) Metabolism Mediated by HYBID (Hyaluronan-binding Protein Involved in HA Depolymerization, KIAA1199) and HA Synthases in Growth Factor-stimulated Fibroblasts.

  10. Electron microscopy structure of PDGFRB (show PDGFRB Proteins) [a full-length human platelet-derived growth factor receptor (show PDGFRL Proteins)], in complex with its ligand PDGF-B (show PDGFB Proteins).

PDGFBB Protein Profile

Protein Summary

The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Alternative names and synonyms associated with PDGFBB

  • platelet-derived growth factor beta polypeptide (PDGFB)
  • c-sis protein
  • PDGF-2 protein
  • PDGF2 protein
  • SIS protein
  • SSV protein

Protein level used designations for PDGFBB

PDGF subunit B , PDGF, B chain , becaplermin , platelet-derived growth factor 2 , platelet-derived growth factor B chain , platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) , platelet-derived growth factor subunit B , platelet-derived growth factor, beta polypeptide (oncogene SIS) , proto-oncogene c-Sis

GENE ID SPECIES
5155 Homo sapiens
Selected quality suppliers for PDGFBB Proteins (PDGFBB)
Did you look for something else?