Browse our anti-TRKB (NTRK2) Antibodies

Full name:
anti-Neurotrophic Tyrosine Kinase, Receptor, Type 2 Antibodies (NTRK2)
On www.antibodies-online.com are 355 Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) Antibodies from 34 different suppliers available. Additionally we are shipping TRKB Kits (50) and TRKB Proteins (38) and many more products for this protein. A total of 469 TRKB products are currently listed.
Synonyms:
AI848316, C030027L06Rik, GP145-TrkB, ntrk2, RATTRKB1, si:ch211-220b11.1, Tkrb, Trk-B, TrkB, trkb-b, TRKB1, trkB2, xtrkb
list all antibodies Gene Name GeneID UniProt
NTRK2 4915 Q16620
NTRK2 18212 P15209
NTRK2 25054 Q63604

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Top referenced anti-TRKB Antibodies

  1. Rat (Rattus) Monoclonal TRKB Primary Antibody for BI, FM - ABIN967745 : Armanini, McMahon, Sutherland, Shelton, Phillips: Truncated and catalytic isoforms of trkB are co-expressed in neurons of rat and mouse CNS. in The European journal of neuroscience 1995 (PubMed)
    Show all 7 references for 967745

  2. Human Polyclonal TRKB Primary Antibody for WB - ABIN319265 : Dua, Singh, Thompson: Associative Classification of Mammograms using Weighted Rules. in Expert systems with applications 2011 (PubMed)
    Show all 4 references for 319265

  3. Human Polyclonal TRKB Primary Antibody for WB - ABIN616053 : Lewis, Hunihan, Franco, Robertson, Palmer, Laurent, Balasubramanian, Li, Westphal: Identification and characterization of compounds that potentiate NT-3-mediated Trk receptor activity. in Molecular pharmacology 2006 (PubMed)
    Show all 4 references for 616053

  4. Human Polyclonal TRKB Primary Antibody for IF - ABIN401582 : Woronowicz, Amith, De Vusser, Laroy, Contreras, Basta, Szewczuk: Dependence of neurotrophic factor activation of Trk tyrosine kinase receptors on cellular sialidase. in Glycobiology 2006 (PubMed)
    Show all 4 references for 401582

  5. Chicken Polyclonal TRKB Primary Antibody for IF, IP - ABIN223287 : Jang, Liu, Pradoldej, Tosini, Chang, Iuvone, Ye: N-acetylserotonin activates TrkB receptor in a circadian rhythm. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)
    Show all 4 references for 223287

  6. Human Polyclonal TRKB Primary Antibody for IHC, ELISA - ABIN1532221 : Nakagawara, Liu, Ikegaki, White, Yamashiro, Nycum, Biegel, Brodeur: Cloning and chromosomal localization of the human TRK-B tyrosine kinase receptor gene (NTRK2). in Genomics 1995 (PubMed)
    Show all 2 references for 1532221

  7. Human Polyclonal TRKB Primary Antibody for FACS, IF (p) - ABIN725870 : Zhu, Xia, Han, Shao, Jing, Fan, Liu, Diao, Lv, Sun: Xiao Yao San Improves Depressive-Like Behavior in Rats through Modulation of ?-Arrestin 2-Mediated Pathways in Hippocampus. in Evidence-based complementary and alternative medicine : eCAM 2014 (PubMed)

  8. Human Monoclonal TRKB Primary Antibody for IHC (p), WB - ABIN410036 : Glueckert, Pritz, Roy, Dudas, Schrott-Fischer: Nanoparticle mediated drug delivery of rolipram to tyrosine kinase B positive cells in the inner ear with targeting peptides and agonistic antibodies. in Frontiers in aging neuroscience 2015 (PubMed)

  9. Human Polyclonal TRKB Primary Antibody for IHC (p), IHC - ABIN408506 : Simmons, Belichenko, Yang, Condon, Monbureau, Shamloo, Jing, Massa, Longo: A small molecule TrkB ligand reduces motor impairment and neuropathology in R6/2 and BACHD mouse models of Huntington's disease. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 (PubMed)

More Antibodies against TRKB Interaction Partners

Zebrafish Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) interaction partners

  1. By immunohistochemistry, the localization of Neurotrophinss has been observed mainly in Purkinje cells; TrkA (show NTRK1 Antibodies) and TrkB-receptors in cells and fibers of granular and molecular layers. TrkC (show NTRK3 Antibodies) was faintly detected

  2. BDNF (show BDNF Antibodies)-TrkB influences the expression level of components of chemokine (show CCL1 Antibodies) signaling including Cxcr4b, and the generation of progenitors of mechanoreceptors, at the level of expression of Atoh1a-Atp2b1a.

  3. Light regulates the expression of the BDNF (show BDNF Antibodies)/TrkB2 system in the adult zebrafish retina.

Rhesus Monkey Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) interaction partners

  1. Study showed that complex relationships exist between BDNF (show BDNF Antibodies)/TrkB gene expression and interneuron marker gene expression that appear to be dependent on the presence of testosterone at adolescence

Human Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) interaction partners

  1. In the current work, we provide a global analysis of the physiological consequences of TrkB receptor activation in vitro and discuss the dynamic consequences of TrkB activation in vivo. Finally, we propose a clinically-feasible option for increasing BDNF (show BDNF Antibodies) expression in the hypothalamus to more readily utilize the oncolytic effects of BDNF (show BDNF Antibodies).

  2. ShcD (show SHC4 Antibodies) binds to active Ret (show RET Antibodies), TrkA (show NTRK1 Antibodies), and TrkB neurotrophic factor (show NTF3 Antibodies) receptors predominantly via its phosphotyrosine-binding (PTB (show PTBP1 Antibodies)) domain.

  3. These findings, while exploratory, indicate that the genotypes of NTRK2 and COMT (show COMT Antibodies) may contribute to relative risk for symptom burden during and shortly after the period of chemotherapy in women with early stage breast cancer.

  4. We demonstrated that downregulation of PHLDA1 (show PHLDA1 Antibodies) leads to a significant increase in expression of Aurora A (show AURKA Antibodies) and TRKB that are markers of poor prognosis in neuroblastoma (show ARHGEF16 Antibodies)

  5. The receptors, TrkB and p75 (show CUX1 Antibodies) are more highly expressed in deep infiltrating endometriosis than in peritoneal tissues.

  6. High expression of NTRK2 is associated with gastric cancer.

  7. Genetic variability of NTRK2, a susceptibility gene for psychiatric disorders, is related to emotional arousal and-independently-to brain white-matter properties in healthy individuals.

  8. High expression of TrkA (show NTRK1 Antibodies), TrkB, or TrkC (show NTRK3 Antibodies) was significantly associated with histopathology

  9. Results show up-regulation of TrkB and down-regulation of Runx3 (show RUNX3 Antibodies) and Keap1 (show KEAP1 Antibodies) in breast cancer cells and suggest that TrkB plays a key role in tumorigenicity and metastasis of breast cancer cells through suppression of Runx3 (show RUNX3 Antibodies) or Keap1 (show KEAP1 Antibodies).

  10. Our data revealed that anoikis-resistant ACHN (show LARP6 Antibodies) cells presented with tolerance to detachment-induced apoptosis, excessive proliferation and aggressive invasion, accompanied by upregulation of TrkB expression in contrast to parental cells

Mouse (Murine) Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) interaction partners

  1. findings show that BDNF (show BDNF Antibodies)-TrkB signaling, rather than Dopamine signaling, in the Ventral Tegmental Area -Nuc (show SREBF2 Antibodies). Accumbens circuit is crucial for facilitating depressive-like depressive-like outcomes after Chronic Social Defeat Stress and they establish BDNF (show BDNF Antibodies)-TrkB signaling as a pathologic mechanism during periods of chronic stress.

  2. inhibition of Sig (show PICALM Antibodies)-1 R prevented cocaine-induced TrkB activation in hippocampal neurons.

  3. After spinal cord injury, astrocyte-specific TrkB knock-out mice showed reduced hyperpathic responses and improved motor coordination.

  4. Results imply that oleanolic acid ameliorates scopolamine-induced memory impairment by modulating the brain-derived neurotrophic factor (show BDNF Antibodies) -ERK1/2 (show MAPK1/3 Antibodies)-cAMP response element-binding protein pathway through tropomyosin receptor kinase (show NTRK1 Antibodies) B activation in mice, suggesting that oleanolic acid would be a potential therapeutic agent for the treatment of cognitive deficits.

  5. Data show that c-Jun NH2-terminal kinase (JNK (show MAPK8 Antibodies))-interacting protein-3 (JIP3 (show MAPK8IP3 Antibodies)) participates in the migration of cortical neurons during cortical development by mediating TrkB receptor axonal anterograde transport.

  6. findings reveal a spine-autonomous, autocrine signalling mechanism involving NMDAR (show GRIN1 Antibodies)-CaMKII (show CAMK2G Antibodies)-dependent BDNF (show BDNF Antibodies) release from stimulated dendritic spines and subsequent TrkB activation on these same spines that is crucial for structural and functional plasticity

  7. Following ethanol administration, phosphorylation of TrkB in the striatum was significantly reduced in wild-type mice.

  8. Results suggest that the therapeutic actions of atypical antidepressant drugs involve various neurocircuits, some of which, but not all, appears to involve BDNF (show BDNF Antibodies)/TrkB and downstream neuroplastic signaling

  9. Observations provide evidence that female-specific induction of estrogen receptor alpha (show ESR1 Antibodies) expression confers neuroprotection with TrkB agonist therapy via Src (show SRC Antibodies) family kinase activation and account for improved functional outcomes in female neonates post-hypoxia and ischemia.

  10. data suggest antidepressant effects of BDNF (show BDNF Antibodies)-TrkB in the NAc (show NLRP1 Antibodies), which could not be explained by activation of the transcription factors CREB (show CREB1 Antibodies) or beta-catenin (show CTNNB1 Antibodies). The effects TrkB has on depression-related behavior in different brain regions appear to critically depend on the targeted cell type.

Cow (Bovine) Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) interaction partners

  1. These observations provided evidence that brain-derived naeurotrophic factor(BDNF (show BDNF Antibodies)) and its receptor (BDNF (show BDNF Antibodies) receptor) secreted by bovine sperm was important in regulation of insulin (show INS Antibodies) and leptin (show LEP Antibodies).

  2. Expressed in ganglionic neuron-like tumor cells, which may activate an embryonic autocrine pathwy involving bdnf (show BDNF Antibodies)-Trk-B

TRKB (NTRK2) Antigen Profile

Antigen Summary

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with TRKB (NTRK2)

  • neurotrophic tyrosine kinase, receptor, type 2 (NTRK2) antibody
  • neurotrophic tyrosine kinase, receptor, type 2 (ntrk2-b) antibody
  • neurotrophic tyrosine kinase, receptor, type 2b (ntrk2b) antibody
  • neurotrophic tyrosine kinase, receptor, type 2 (ntrk2-a) antibody
  • neurotrophic tyrosine kinase, receptor, type 2 (ntrk2) antibody
  • neurotrophic tyrosine kinase, receptor, type 2 (Ntrk2) antibody
  • AI848316 antibody
  • C030027L06Rik antibody
  • GP145-TrkB antibody
  • ntrk2 antibody
  • RATTRKB1 antibody
  • si:ch211-220b11.1 antibody
  • Tkrb antibody
  • Trk-B antibody
  • TrkB antibody
  • trkb-b antibody
  • TRKB1 antibody
  • trkB2 antibody
  • xtrkb antibody

Protein level used designations for NTRK2

neurotrophin receptor B xTrkB-alpha , BDNF/NT-3 growth factors receptor , neurotrophic tyrosine kinase, receptor, type 2 , BDNF/NT-3 growth factors receptor-like , neurotrophic tyrosine kinase receptor type 2 , trk-B , trkB tyrosine kinase , tyrosine kinase receptor , BDNF-tropomyosine receptor kinase B , tropomyosin-related kinase B , tyrosine kinase receptor B , GP145-TrkB/GP95-TrkB , neural receptor protein-tyrosine kinase (trkB) , trkB protein

GENE ID SPECIES
100061700 Equus caballus
379266 Xenopus laevis
570240 Danio rerio
709757 Macaca mulatta
735394 Pan troglodytes
779173 Xenopus laevis
780110 Xenopus (Silurana) tropicalis
100388984 Callithrix jacchus
100441207 Pongo abelii
396157 Gallus gallus
4915 Homo sapiens
18212 Mus musculus
25054 Rattus norvegicus
484147 Canis lupus familiaris
505824 Bos taurus
100352548 Oryctolagus cuniculus
100723565 Cavia porcellus
100519209 Sus scrofa
101116015 Ovis aries
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