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Browse our anti-TRKB (NTRK2) Antibodies

Full name:
anti-Neurotrophic Tyrosine Kinase, Receptor, Type 2 Antibodies (NTRK2)
On are 337 Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) Antibodies from 33 different suppliers available. Additionally we are shipping TRKB Kits (43) and TRKB Proteins (33) and many more products for this protein. A total of 439 TRKB products are currently listed.
AI848316, C030027L06Rik, GP145-TrkB, ntrk2, RATTRKB1, si:ch211-220b11.1, Tkrb, Trk-B, TrkB, trkb-b, TRKB1, trkB2, xtrkb
list all antibodies Gene Name GeneID UniProt
NTRK2 4915 Q16620
NTRK2 18212 P15209
NTRK2 25054 Q63604

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Top referenced anti-TRKB Antibodies

  1. Rat (Rattus) Monoclonal TRKB Primary Antibody for BI, FM - ABIN967745 : Armanini, McMahon, Sutherland, Shelton, Phillips: Truncated and catalytic isoforms of trkB are co-expressed in neurons of rat and mouse CNS. in The European journal of neuroscience 1995 (PubMed)
    Show all 7 references for ABIN967745

  2. Human Polyclonal TRKB Primary Antibody for WB - ABIN319265 : Dua, Singh, Thompson: Associative Classification of Mammograms using Weighted Rules. in Expert systems with applications 2011 (PubMed)
    Show all 4 references for ABIN319265

  3. Human Polyclonal TRKB Primary Antibody for WB - ABIN616053 : Lewis, Hunihan, Franco, Robertson, Palmer, Laurent, Balasubramanian, Li, Westphal: Identification and characterization of compounds that potentiate NT-3-mediated Trk receptor activity. in Molecular pharmacology 2006 (PubMed)
    Show all 4 references for ABIN616053

  4. Human Polyclonal TRKB Primary Antibody for IF - ABIN401582 : Woronowicz, Amith, De Vusser, Laroy, Contreras, Basta, Szewczuk: Dependence of neurotrophic factor activation of Trk tyrosine kinase receptors on cellular sialidase. in Glycobiology 2006 (PubMed)
    Show all 4 references for ABIN401582

  5. Chicken Polyclonal TRKB Primary Antibody for IF, IP - ABIN223287 : Jang, Liu, Pradoldej, Tosini, Chang, Iuvone, Ye: N-acetylserotonin activates TrkB receptor in a circadian rhythm. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)
    Show all 4 references for ABIN223287

  6. Human Polyclonal TRKB Primary Antibody for IHC, ELISA - ABIN1532221 : Nakagawara, Liu, Ikegaki, White, Yamashiro, Nycum, Biegel, Brodeur: Cloning and chromosomal localization of the human TRK-B tyrosine kinase receptor gene (NTRK2). in Genomics 1995 (PubMed)
    Show all 2 references for ABIN1532221

  7. Human Monoclonal TRKB Primary Antibody for IF, IHC - ABIN2452423 : Inoue, Hur, Kihara, Teranishi, Yamamoto, Ishikawa, Wiehager, Winblad, Tjernberg, Schedin-Weiss: Human brain proteins showing neuron-specific interactions with ?-secretase. in The FEBS journal 2015 (PubMed)

  8. Human Polyclonal TRKB Primary Antibody for FACS, IF (p) - ABIN725870 : Zhu, Xia, Han, Shao, Jing, Fan, Liu, Diao, Lv, Sun: Xiao Yao San Improves Depressive-Like Behavior in Rats through Modulation of ?-Arrestin 2-Mediated Pathways in Hippocampus. in Evidence-based complementary and alternative medicine : eCAM 2014 (PubMed)

  9. Human Polyclonal TRKB Primary Antibody for IHC (p), IHC - ABIN408506 : Simmons, Belichenko, Yang, Condon, Monbureau, Shamloo, Jing, Massa, Longo: A small molecule TrkB ligand reduces motor impairment and neuropathology in R6/2 and BACHD mouse models of Huntington's disease. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 (PubMed)

More Antibodies against TRKB Interaction Partners

Zebrafish Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) interaction partners

  1. BDNF (show BDNF Antibodies)-TrkB influences the expression level of components of chemokine (show CCL1 Antibodies) signaling including Cxcr4b, and the generation of progenitors of mechanoreceptors, at the level of expression of Atoh1a-Atp2b1a.

  2. Light regulates the expression of the BDNF (show BDNF Antibodies)/TrkB2 system in the adult zebrafish retina.

Rhesus Monkey Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) interaction partners

  1. Study showed that complex relationships exist between BDNF (show BDNF Antibodies)/TrkB gene expression and interneuron marker gene expression that appear to be dependent on the presence of testosterone at adolescence

Human Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) interaction partners

  1. High expression of NTRK2 is associated with gastric cancer.

  2. Genetic variability of NTRK2, a susceptibility gene for psychiatric disorders, is related to emotional arousal and-independently-to brain white-matter properties in healthy individuals.

  3. High expression of TrkA (show NTRK1 Antibodies), TrkB, or TrkC (show NTRK3 Antibodies) was significantly associated with histopathology

  4. Results show up-regulation of TrkB and down-regulation of Runx3 (show RUNX3 Antibodies) and Keap1 (show KEAP1 Antibodies) in breast cancer cells and suggest that TrkB plays a key role in tumorigenicity and metastasis of breast cancer cells through suppression of Runx3 (show RUNX3 Antibodies) or Keap1 (show KEAP1 Antibodies).

  5. Our data revealed that anoikis-resistant ACHN (show LARP6 Antibodies) cells presented with tolerance to detachment-induced apoptosis, excessive proliferation and aggressive invasion, accompanied by upregulation of TrkB expression in contrast to parental cells

  6. results demonstrate the occurrence of ASIC2 (show ACCN1 Antibodies) and TrkB in the human intervertebral disc (IVD (show IVD Antibodies)), and the increased expression of both in pathological IVD (show IVD Antibodies) suggest their involvement in IVD (show IVD Antibodies) degeneration

  7. Data indicate the role of tropomyosin-related kinase-B (TrkB) in activation of the interleukin-6 (show IL6 Antibodies)/Janus kinase 2 (show JAK2 Antibodies)/STAT3 (show STAT3 Antibodies) transcription factor and PI3 kinase (show PIK3CA Antibodies)/c-AKT (show AKT1 Antibodies) proto-oncogene (show RAB1A Antibodies) protein pathway in breast cancer.

  8. soluble Abeta42 and BDNF (show BDNF Antibodies), but not TrkB or soluble tau, correlate with dementia in the oldest-old

  9. The rare variants in NTRK2 were significantly associated with smoking status.

  10. Entrectinib inhibits growth of TrkB expressing neuroblastoma (show ARHGEF16 Antibodies) cells in vitro and in vivo, and that it enhances the efficacy of conventional chemotherapy in in vivo models.

Mouse (Murine) Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) interaction partners

  1. findings reveal a spine-autonomous, autocrine signalling mechanism involving NMDAR (show GRIN1 Antibodies)-CaMKII (show CAMK2G Antibodies)-dependent BDNF (show BDNF Antibodies) release from stimulated dendritic spines and subsequent TrkB activation on these same spines that is crucial for structural and functional plasticity

  2. Following ethanol administration, phosphorylation of TrkB in the striatum was significantly reduced in wild-type mice.

  3. Results suggest that the therapeutic actions of atypical antidepressant drugs involve various neurocircuits, some of which, but not all, appears to involve BDNF (show BDNF Antibodies)/TrkB and downstream neuroplastic signaling

  4. Observations provide evidence that female-specific induction of estrogen receptor alpha (show ESR1 Antibodies) expression confers neuroprotection with TrkB agonist therapy via Src (show SRC Antibodies) family kinase activation and account for improved functional outcomes in female neonates post-hypoxia and ischemia.

  5. data suggest antidepressant effects of BDNF (show BDNF Antibodies)-TrkB in the NAc (show NLRP1 Antibodies), which could not be explained by activation of the transcription factors CREB (show CREB1 Antibodies) or beta-catenin (show CTNNB1 Antibodies). The effects TrkB has on depression-related behavior in different brain regions appear to critically depend on the targeted cell type.

  6. Study indicates that diminished mature BDNF (show BDNF Antibodies) trophic signaling through the TrkB receptor, rather than an induction in proBDNF, is a main contributing factor to the vulnerability of striatal neurons in the zQ175 HD mouse model

  7. TrkB is an endothelial injury-response molecule in atherogenesis. Endothelial brain-derived neurotrophic factor (show BDNF Antibodies)/TrkB signaling reduces VE-cadherin (show CDH5 Antibodies) shedding and protects against atherosclerotic lesion development in ApoE (show APOE Antibodies)-/- mice.

  8. Brain ischaemia induces shedding of a BDNF (show BDNF Antibodies)-scavenger ectodomain from TrkB receptors by excitotoxicity activation of metalloproteinases and gamma-secretases.

  9. Brain-derived neurotrophic factor (BDNF (show BDNF Antibodies)) and its specific receptor, tropomyosin (show TPM2 Antibodies)-related kinase (TrkB), have a role the in pathophysiology of depression.

  10. Expression of the dominant-negative BDNF (show BDNF Antibodies) receptor TrkB receptor in the majority of pyramidal neurons in adult visual cortex has strikingly different effects on cortical wiring than expression of the same transgene in a sparse neuron population.

Cow (Bovine) Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) interaction partners

  1. These observations provided evidence that brain-derived naeurotrophic factor(BDNF (show BDNF Antibodies)) and its receptor (BDNF (show BDNF Antibodies) receptor) secreted by bovine sperm was important in regulation of insulin (show INS Antibodies) and leptin (show LEP Antibodies).

  2. Expressed in ganglionic neuron-like tumor cells, which may activate an embryonic autocrine pathwy involving bdnf (show BDNF Antibodies)-Trk-B

TRKB (NTRK2) Antigen Profile

Antigen Summary

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with TRKB (NTRK2)

  • neurotrophic tyrosine kinase, receptor, type 2 (NTRK2) antibody
  • neurotrophic tyrosine kinase, receptor, type 2 (ntrk2-b) antibody
  • neurotrophic tyrosine kinase, receptor, type 2b (ntrk2b) antibody
  • neurotrophic tyrosine kinase, receptor, type 2 (ntrk2-a) antibody
  • neurotrophic tyrosine kinase, receptor, type 2 (ntrk2) antibody
  • neurotrophic tyrosine kinase, receptor, type 2 (Ntrk2) antibody
  • AI848316 antibody
  • C030027L06Rik antibody
  • GP145-TrkB antibody
  • ntrk2 antibody
  • RATTRKB1 antibody
  • si:ch211-220b11.1 antibody
  • Tkrb antibody
  • Trk-B antibody
  • TrkB antibody
  • trkb-b antibody
  • TRKB1 antibody
  • trkB2 antibody
  • xtrkb antibody

Protein level used designations for NTRK2

neurotrophin receptor B xTrkB-alpha , BDNF/NT-3 growth factors receptor , neurotrophic tyrosine kinase, receptor, type 2 , BDNF/NT-3 growth factors receptor-like , neurotrophic tyrosine kinase receptor type 2 , trk-B , trkB tyrosine kinase , tyrosine kinase receptor , BDNF-tropomyosine receptor kinase B , tropomyosin-related kinase B , tyrosine kinase receptor B , GP145-TrkB/GP95-TrkB , neural receptor protein-tyrosine kinase (trkB) , trkB protein

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