TRKB antibody (AA 207-339)

Catalog No. ABIN5542348

The Mouse Monoclonal anti-TRKB antibody (Clone 10B6C4) (ABIN5542348) specifically detects TRKB in IHC and ELISA. The antibody is reactive with Human samples.

Quick Overview for TRKB antibody (AA 207-339) (ABIN5542348)

Target: TRKB (NTRK2) (Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TRKB antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Clone: 10B6C4

Product Details anti-TRKB Antibody

Binding Specificity: AA 207-339

Purpose: NTRK2 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human NTRK2 (AA: 207-339) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for TRKB

Target: TRKB (NTRK2) (Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))

Alternative Name: NTRK2

Background: This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.

Molecular Weight: 92 kDa

Gene ID: 4915

UniProt: Q16620

Pathways: RTK Signaling, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Skeletal Muscle Fiber Development, Feeding Behaviour, Dicarboxylic Acid Transport