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Browse our TSC1 (TSC1) ELISA Kits

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Tuberous Sclerosis 1 ELISA Kits (TSC1)
On are 2 Tuberous Sclerosis 1 (TSC1) ELISA Kits from 1 different suppliers available. Additionally we are shipping TSC1 Antibodies (836) and TSC1 Proteins (3) and many more products for this protein. A total of 857 TSC1 products are currently listed.
hamartin, LAM, mKIAA0243, TSC, tsc1, wu:fc38b04
list all ELISA KIts Gene Name GeneID UniProt
Human TSC1 TSC1 7248 Q92574
TSC1 64930 Q9EP53
TSC1 60445 Q9Z136

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TSC1 (TSC1) ELISA Kits by Reactivity

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More ELISA Kits for TSC1 Interaction Partners

Zebrafish Tuberous Sclerosis 1 (TSC1) interaction partners

  1. Tsc1 is involved in regulation of interactive network between the cilium and the TOR pathway.

Human Tuberous Sclerosis 1 (TSC1) interaction partners

  1. Gene expression level of TSC1 is significantly higher in AD patients when compared to normal controls.

  2. Each TBC1D7 (show TBC1D7 ELISA Kits) molecule interacts simultaneously with two parallel TSC1 helices from two TSC1 molecules, suggesting that TBC1D7 (show TBC1D7 ELISA Kits) may stabilize the TSC (show SLC12A3 ELISA Kits) complex by tethering the C-terminal ends of two TSC1 coiled-coils.

  3. IQ/DQ correlates inversely with predicted levels and/or deleterious biochemical effects of mutant TSC1 or TSC2 (show TSC2 ELISA Kits) protein in tuberous sclerosis complex.

  4. AKT3 (show AKT3 ELISA Kits) has a role in prostate cancer proliferation through regulation of Akt (show AKT1 ELISA Kits), B-Raf (show SNRPE ELISA Kits), and TSC1/TSC2 (show TSC2 ELISA Kits)

  5. Tsc1 transgenic mice exhibit an age-dependent seizure pattern sequence mimicking early human tuberous sclerosis complex epilepsy.

  6. PAK2 (show PAK2 ELISA Kits) is a direct effector of TSC1-TSC2 (show TSC2 ELISA Kits)-RHEB (show RHEB ELISA Kits) signaling and a new target for rational drug therapy in TSC (show SLC12A3 ELISA Kits).

  7. These findings indicate that Tsc1 prevents aberrant renal growth and tumorigenesis by inhibiting mTORC1 signaling, whereas phosphorylated rpS6 (show RPS6 ELISA Kits) suppresses cystogenesis and fibrosis in Tsc1-deleted kidneys

  8. Data show that 10 pathogenic mutations were quickly identified, 7 were located in tuberous sclerosis 1 protein (TSC1) and 3 were observed in tuberous sclerosis 2 protein (TSC2 (show TSC2 ELISA Kits)).

  9. Tuberous sclerosis is a syndrome caused by dominant mutations in Hamartin (TSC1),causing Autism spectrum disorder - like behaviors, seizures, intellectual disability and characteristic brain and skin lesions.

  10. TSC1 and TSC2 (show TSC2 ELISA Kits) mutations are associated with tuberous sclerosis.

Mouse (Murine) Tuberous Sclerosis 1 (TSC1) interaction partners

  1. suppression of AKT (show AKT1 ELISA Kits) by hyperactivation of mTORC1, inhibition on nuclear ERalpha (show ESR1 ELISA Kits) signaling, and down-regulation of cell-cycle-driving proteins play important roles in the retarded mammary development induced by Tsc1 deletion.

  2. TSC1 knockout mice are lean, glucose intolerant with a decreased activation of protein kinase B (Akt/PKB (show AKT1 ELISA Kits)) targets that regulate glucose transporters in skeletal muscle.

  3. a pivotal role for Tsc1 in regulating various aspects of visual-pathway development, is reported.

  4. PAK2 (show PAK2 ELISA Kits) is a direct effector of TSC1-TSC2 (show TSC2 ELISA Kits)-RHEB (show RHEB ELISA Kits) signaling and a new target for rational drug therapy in TSC (show SLC12A3 ELISA Kits).

  5. Tsc1 plays a critical role in regulating macrophage survival, function and polarization via inhibition of mTORC1 activity.

  6. TSC1-KO results in the accumulation of transitional-1 B cells and progressive losses of B cells as they mature beyond the T1 stage. However, Peyer's patch germinal centers are unimpaired in TSC1-KO mice.

  7. TSC1 deletion led to enhanced mTORC1 signaling in neural crest derived bones and the increase in bone formation is responsible for the aberrantly increased bone mass.

  8. Results describe the development of new vascular mouse model with a conditional knockout allele of Tsc1 with a Darpp32 (show PPP1R1B ELISA Kits)-Cre allele. This mouse displayed accelerated formation of both kidney cystadenomas and paw hemangiosarcomas.

  9. PLK1 (show PLK1 ELISA Kits) protein levels are increased in hamartin and tuberin (show TSC2 ELISA Kits) deficient cells and Lymphangioleiomyomatosis patient-derived specimens, and that this increase is rapamycin-sensitive.

  10. Tuberless heterozygote Tsc1+/- mice show functional up-regulation of cortical GluN2C (show GRIN2C ELISA Kits) receptors in an mTOR (show FRAP1 ELISA Kits)-dependent manner, exhibit recurrent, unprovoked seizures during early postnatal life, that can be treated with GluN2C (show GRIN2C ELISA Kits) antagonists.

TSC1 Antigen Profile

Antigen Summary

This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with TSC1

  • tuberous sclerosis 1 (TSC1) Elisa Kit
  • tuberous sclerosis 1b (tsc1b) Elisa Kit
  • tuberous sclerosis 1 (tsc1) Elisa Kit
  • tuberous sclerosis 1 (Tsc1) Elisa Kit
  • hamartin Elisa Kit
  • LAM Elisa Kit
  • mKIAA0243 Elisa Kit
  • TSC Elisa Kit
  • tsc1 Elisa Kit
  • wu:fc38b04 Elisa Kit

Protein level used designations for Tuberous Sclerosis 1 (TSC1) ELISA Kits

tuberous sclerosis 1 protein , tuberous sclerosis 1 , fc38b04 , hamartin , hamartin-like , tumor suppressor , tuberous sclerosis 1 protein homolog , chromosome 9 TSC1

100066615 Equus caballus
464818 Pan troglodytes
100017591 Monodelphis domestica
100080641 Ornithorhynchus anatinus
100330617 Danio rerio
100338695 Oryctolagus cuniculus
100380126 Xenopus (Silurana) tropicalis
100407741 Callithrix jacchus
100471530 Ailuropoda melanoleuca
100539473 Meleagris gallopavo
100587112 Nomascus leucogenys
7248 Homo sapiens
64930 Mus musculus
60445 Rattus norvegicus
480688 Canis lupus familiaris
100154726 Sus scrofa
533440 Bos taurus
417166 Gallus gallus
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