Browse our TSC2 (TSC2) ELISA Kits

Full name:
Tuberous Sclerosis 2 ELISA Kits (TSC2)
On www.antibodies-online.com are 14 Tuberous Sclerosis 2 (TSC2) ELISA Kits from 8 different suppliers available. Additionally we are shipping TSC2 Antibodies (746) and and many more products for this protein. A total of 783 TSC2 products are currently listed.
Synonyms:
fc16b02, LAM, Nafld, Rc, Tcs2, TSC2, TSC4, tuberin, wu:fc16b02
list all ELISA KIts Gene Name GeneID UniProt
TSC2 7249 P49815
TSC2 22084  
TSC2 24855 P49816

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Top referenced TSC2 ELISA Kits

  1. General TSC2 ELISA Kit for Competition ELISA - ABIN1140792 : Feruglio, Trøseid, Damås, Kvale, Dyrhol-Riise: Soluble markers of the Toll-like receptor 4 pathway differentiate between active and latent tuberculosis and are associated with treatment responses. in PLoS ONE 2013 (PubMed)

More ELISA Kits for TSC2 Interaction Partners

Zebrafish Tuberous Sclerosis 2 (TSC2) interaction partners

  1. This is the first report using an animal model to show interactions between tsc2, mTORC1 and p53 (show TP53 ELISA Kits) during tumorigenesis.

  2. These results demonstrate a highly conserved role of tsc2 in zebrafish and establish a new animal model for studies of Tuberous sclerosis complex.

Human Tuberous Sclerosis 2 (TSC2) interaction partners

  1. Novel missense mutation in the exon 19 of the TSC2 gene is associated with tuberous sclerosis.

  2. our findings suggest the significance of previously undocumented mutation-dependent mTOR (show FRAP1 ELISA Kits) hyperactivation and frequent TSC1 (show TSC1 ELISA Kits)/2 mutations in HBV-associated HCCs (show HCCS ELISA Kits). They define a molecular subset of HCC (show FAM126A ELISA Kits) having genetic aberrations in mTOR (show FRAP1 ELISA Kits) signalling, with potential significance of effective specific drug therapy.

  3. Mutation in TSC2 is associated with lymphangioleiomyomatosis.

  4. Results show that tuberous sclerosis complex disease segregates with a silent substitution in TSC2, c.4149C>T, p.(Ser1838Ser), which leads to the formation of an active donor splice site, resulting in three shorter alternatively spliced transcripts with premature stop codons.

  5. Clinical whole exome sequencing of blood and tumor samples con (show DISP1 ELISA Kits) fi rmed the diagnosis of methylmalonic acidemia and revealed two somatic inactivating mutations in TSC2, suggesting the potential consideration of an mTOR (show FRAP1 ELISA Kits) inhibitor in the event of tumor recurrence.

  6. TSC2 N-terminal lysine acetylation status affects to its stability modulating mTORC1 signaling and autophagy/cell proliferation.

  7. The mTOR (show FRAP1 ELISA Kits)-dependent, epithelial phenotype of TSC (show SLC12A3 ELISA Kits) astrocytes suggests TSC1 (show TSC1 ELISA Kits)/2 and mTOR (show FRAP1 ELISA Kits) tune the phosphorylation level of catenin delta-1 (show CTNND1 ELISA Kits) by controlling PKCe (show PRKCE ELISA Kits) activity, thereby regulating the mesenchymal-epithelial-transition (MET)

  8. TSC2 mutations leading to severe tuberous sclerosis in Chinese children.

  9. Our results indicate that TSC2 and less commonly TSC1 (show TSC1 ELISA Kits) alterations are the primary essential driver event in angiomyolipoma/Lymphangioleiomyomatosis, whereas other somatic mutations are rare and likely do not contribute to tumor development.

  10. These results suggested that TSC2 heterozygosity caused neurological malformations in primitive neural stem cells, indicating that its heterozygosity might be sufficient for the development of neurological abnormalities in patients.

Mouse (Murine) Tuberous Sclerosis 2 (TSC2) interaction partners

  1. Tsc2-mTOR (show FRAP1 ELISA Kits) signaling in mesenchyme is essential for the maintenance of renal structure and for lung alveolarization.

  2. TSC1 (show TSC1 ELISA Kits)/TSC2 complex upregulation of OPN (show SPP1 ELISA Kits) expression is mediated by transcription factor SOX9 (show SOX9 ELISA Kits) in an mTOR (show FRAP1 ELISA Kits)-independent manner. Moreover, ablation of OPN (show SPP1 ELISA Kits) by deficient TSC1 (show TSC1 ELISA Kits)/TSC2 complex contributed to inactivation of AKT (show AKT1 ELISA Kits) in TSC (show SLC12A3 ELISA Kits) cells

  3. Rheb (show RHEB ELISA Kits) and TSC2 have roles in the mechanical activation of mTOR (show FRAP1 ELISA Kits) signaling

  4. this study shows that TSC2 maintains macrophage quiescence and prevents mTORC1-dependent granulomatous disease with clinical implications for sarcoidosis

  5. TSC2 N-terminal lysine acetylation status affects to its stability modulating mTORC1 signaling and autophagy/cell proliferation.

  6. Repression of TSC1 (show TSC1 PLURAL_@12100@)/TSC2 mediated by MeCP2 (show MECP2 PLURAL_@12100@) regulates human embryo lung fibroblast cell differentiation and proliferation.

  7. Formation of ROS (show ROS1 ELISA Kits) and activity of NADPH (show FDXR ELISA Kits) oxidases were significantly higher in mouse embryonic fibroblasts and in primary culture of rat renal proximal tubular epithelial tuberin-deficient cells compared to wild-type cells.

  8. Data suggest that pathological cardiac hypertrophy involved class I histone deacetylases HDAC1 (show HDAC1 ELISA Kits) and HdAC2 (show HDAC2 ELISA Kits), tuberous sclerosis complex 2 (TSC2), and mTOR (show FRAP1 ELISA Kits) srine-threonine kinases (mTOR (show FRAP1 ELISA Kits)).

  9. autophagy via the TSC2-mTORC1 signaling pathway plays an important role in maintenance of cardiac function and mitochondrial quantity and size in the heart.

  10. PAK2 (show PAK2 ELISA Kits) is a direct effector of TSC1 (show TSC1 ELISA Kits)-TSC2-RHEB (show RHEB ELISA Kits) signaling and a new target for rational drug therapy in TSC (show SLC12A3 ELISA Kits).

Pig (Porcine) Tuberous Sclerosis 2 (TSC2) interaction partners

  1. Porcine circovirus type 2 (PCV2) might induce autophagy via the AMPK (show PRKAA1 ELISA Kits)/ERK (show MAPK1 ELISA Kits)/TSC2/mTOR (show FRAP1 ELISA Kits) signaling pathway in the host cells, representing a pivotal mechanism for PCV2 pathogenesis

Cow (Bovine) Tuberous Sclerosis 2 (TSC2) interaction partners

  1. prostaglandin F2alpha phosphorylates TSC2 and activates mTOR (show FRAP1 ELISA Kits) and ribosomal protein S6 (show RPS6 ELISA Kits) kinase (show RPS6KB1 ELISA Kits) signaling in an AKT (show AKT1 ELISA Kits)-independent manner

TSC2 Antigen Profile

Antigen Summary

Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with TSC2

  • tuberous sclerosis 2 (TSC2) Elisa Kit
  • tuberous sclerosis complex 2 (TSC2) (AaeL_AAEL007712) Elisa Kit
  • tuberous sclerosis 2 (tsc2) Elisa Kit
  • tuberous sclerosis 2 (PGTG_00159) Elisa Kit
  • tuberous sclerosis 2 (Tsc2) Elisa Kit
  • fc16b02 Elisa Kit
  • LAM Elisa Kit
  • Nafld Elisa Kit
  • Rc Elisa Kit
  • Tcs2 Elisa Kit
  • TSC2 Elisa Kit
  • TSC4 Elisa Kit
  • tuberin Elisa Kit
  • wu:fc16b02 Elisa Kit

Protein level used designations for Tuberous Sclerosis 2 (TSC2) ELISA Kits

tuberous sclerosis complex 2 (TSC2) , tuberous sclerosis 2 , tuberin-like , tuberin , tuberous sclerosis 2 protein , tuberous sclerosis 2 protein homolog , renal carcinoma , tuberous sclerosis 2 homolog protein

GENE ID SPECIES
100065679 Equus caballus
5569538 Aedes aegypti
468086 Pan troglodytes
567524 Danio rerio
694965 Macaca mulatta
10528144 Puccinia graminis f. sp. tritici CRL 75-36-700-3
100170546 Xenopus (Silurana) tropicalis
100390664 Callithrix jacchus
7249 Homo sapiens
22084 Mus musculus
24855 Rattus norvegicus
479883 Canis lupus familiaris
100505408 Sus scrofa
504985 Bos taurus
416552 Gallus gallus
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