Browse our COL1A1 Proteins (COL1A1)

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Collagen, Type I, alpha 1 Proteins (COL1A1)
On are 12 Collagen, Type I, alpha 1 (COL1A1) Proteins from 6 different suppliers available. Additionally we are shipping COL1A1 Antibodies (174) and COL1A1 Kits (39) and many more products for this protein. A total of 231 COL1A1 products are currently listed.
Col1a-1, COL1A1, COL1A2, Cola-1, Cola1, COLIA1, MGC52532, Mov-13, Mov13, OI4
list all proteins Gene Name GeneID UniProt
COL1A1 1277 P02452
COL1A1 12842 P11087
COL1A1 29393 P02454

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COL1A1 Proteins (COL1A1) by Origin

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More Proteins for COL1A1 Interaction Partners

Human Collagen, Type I, alpha 1 (COL1A1) interaction partners

  1. Depletion of FKBP65 (show FKBP10 Proteins) and inhibition of FKBP65 (show FKBP10 Proteins) activity reduced the dimeric (active) form of LH2 (show PLOD2 Proteins) but did not affect the binding of monomeric (inactive) LH2 (show PLOD2 Proteins) to procollagen Ialpha1.

  2. COL11A1 as a highly specific biomarker of activated cancer-associated fibroblasts in epithelial cancers.

  3. miR (show MLXIP Proteins)-29b can reduce collagen biosynthesis during skin wound healing likely via post-transcriptional inhibition of HSP47 (show SERPINH1 Proteins) expression.

  4. overexpressed miR185 could inhibit hypertrophic scarring fibroblast growth, and the underlying mechanism was mediated, at least partly, through the suppression of TGFbeta1 and Col1 expression.

  5. TGFbeta (show TGFB1 Proteins) elevated the expression of CamK (show CAMK4 Proteins) IIbeta and CamK (show CAMK4 Proteins) IIdelta, while siRNA silencing of those two subtypes significantly reduced TGFbeta (show TGFB1 Proteins)-mediated expression of collagen A1 and fibronectin 1 (show FN1 Proteins).

  6. Femoral and tibial cartilage show a different behaviour concerning expression values for the genes Col1A1, Col2A1 (show COL2A1 Proteins) and Agg.

  7. COL1A2 (show COL1A2 Proteins) mRNA expression was significantly higher in malignant tissues from gastric cancer than in premalignant and normal tissues.

  8. The authors have identified 5 novel mutations in COL1A1 gene implicated in osteogenesis imperfect in a Czech population.

  9. These findings may improve understanding of the pathogenic gene mutation spectrum and the clinical manifestations of mutations of COL1A1 and COL1A2 (show COL1A2 Proteins) genes in Chinese patients with OI.

  10. Data indicate that binding of hemoblobin (Hb) to glycoprotein1balpha (GP1balpha) induced platelet activation plays a crucial role in thrombus formation on immobilized von Willebrand factor (VWF (show VWF Proteins)) or type I collagen under shear stresses.

Mouse (Murine) Collagen, Type I, alpha 1 (COL1A1) interaction partners

  1. collagen-I-mediated inhibition of proplatelet formation is specifically controlled by GPVI (show GP6 Proteins).

  2. miR (show MLXIP Proteins)-29b can reduce collagen biosynthesis during skin wound healing likely via post-transcriptional inhibition of HSP47 (show SERPINH1 Proteins) expression.

  3. Col1a1Jrt/+ mutant mice produce craniofacial and dental defects consistent with osteogenesis imperfecta (show COL1A2 Proteins) and Ehlers-Danlos syndrome

  4. the rate of collagen I degradation was increased in Poldip2 (show POLDIP2 Proteins)(+/-) vs. Poldip2 (show POLDIP2 Proteins)(+/+) MASMs. Conversely, activation of the PI3K/Akt (show AKT1 Proteins)/mTOR (show FRAP1 Proteins) signaling pathway, involved in regulation of protein synthesis, was significantly elevated in Poldip2 (show POLDIP2 Proteins)(+/-) MASMs as was beta1-integrin expression.

  5. Col1 expression was seen in the cartilage zone of the mandibular condyle cartilage.

  6. HRG (show HRG Proteins) binds to alpha2 integrin through low-affinity interactions in a heparin sulfate-independent manner, thereby blocking endothelial cells adhesion to collagen I.

  7. Calreticulin (show CALR Proteins) in mediates vascular smooth muscle cell responses to injury through the regulation of collagen deposition and neointima formation.

  8. Homocysteine Induces Collagen I Expression by Downregulating Histone Methyltransferase G9a (show EHMT2 Proteins)

  9. These data suggested that intestinal epithelial cells were injured after IM treatment through the pVHL (show VHL Proteins) overexpression-induced degradation of collagen I or HIF-1alpha (show HIF1A Proteins).

  10. lipid nanoparticles loaded with small interfering RNA to the procollagen alpha1(I) gene specifically reduce total hepatic collagen content without detectable side effects, potentially qualifying as a therapy for fibrotic liver diseases

Cow (Bovine) Collagen, Type I, alpha 1 (COL1A1) interaction partners

  1. These observations support a signaling network among JNKs, Smads, Snail1 (show SNAI1 Proteins), and cortactin (show CTTN Proteins) to regulate the invasion of MDA-MB-231 cells embedded in 3D collagen I, which may be targeted during screening of anti-invasion reagents.

  2. Data show that biglycan (show BGN Proteins), collagen type I, collagen type II, decorin (show DCN Proteins), and versican (show Vcan Proteins) were significantly affected by vibration duration, frequency, and amplitude.

  3. specific ADAMTS-2 domains cleave the aminopropeptide of fibrillar procollagens types I-III and V

  4. In advanced stage granulomas in Mycobacterium bovis-infected cattle, there was an increase in the expression of type I procollagen (show COL1A2 Proteins)

  5. These results demonstrate a novel and important functional role of the DDR2 (show DDR2 Proteins) extracellular domain that may contribute to collagen regulation via modulation of fibrillogenesis.

  6. Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.

  7. A molecular model of collagen hydration is used to validate centrifugal dehydration force (CDF (show CTNNA2 Proteins)) and re-hydration isotherm (RHI) methods to measure and characterize hydration compartments on bovine tendon.

Pig (Porcine) Collagen, Type I, alpha 1 (COL1A1) interaction partners

COL1A1 Protein Profile

Protein Summary

This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

Alternative names and synonyms associated with COL1A1

  • collagen, type I, alpha 1 (col1a1)
  • collagen, type I, alpha 1 (COL1A1)
  • collagen 1a1 (col1a1)
  • collagen, type I, alpha 1 (Col1a1)
  • Col1a-1 protein
  • COL1A1 protein
  • COL1A2 protein
  • Cola-1 protein
  • Cola1 protein
  • COLIA1 protein
  • MGC52532 protein
  • Mov-13 protein
  • Mov13 protein
  • OI4 protein

Protein level used designations for COL1A1

collagen, type I, alpha 1 , alpha 1 type I collagen , collagen, type I, alpha 2 , collagen type I alpha 1 , procollagen alpha 1 (I) , collagen 1a1 , alpha-1 type I collagen , collagen alpha 1 chain type I , collagen alpha-1(I) chain , collagen alpha-1(I) chain preproprotein , collagen of skin, tendon and bone, alpha-1 chain , pro-alpha-1 collagen type 1 , alpha-1 type 1 collagen , procollagen, type I, alpha 1 , alpha-1 collagen (I) , collagen alpha-1 chain , type I collagen pre-pro-alpha1(I) chain , prepro-alpha-1 collagen type I , type I collagen alpha 1 chain , type I collagen alpha1 , pro-alpha-1 type 1 collagen , collagen, type 1, alpha 1 , procollagen type I, alpha 1 , procollagen, type 1, alpha 1

380515 Xenopus laevis
443483 Ovis aries
455117 Pan troglodytes
574201 Macaca mulatta
100033877 Equus caballus
100135778 Oncorhynchus mykiss
1277 Homo sapiens
12842 Mus musculus
282187 Bos taurus
395532 Gallus gallus
403651 Canis lupus familiaris
100008952 Oryctolagus cuniculus
397571 Sus scrofa
100733209 Cavia porcellus
29393 Rattus norvegicus
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