Browse our DIAPH1 (DIAPH1) ELISA Kits

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Diaphanous Homolog 1 (Drosophila) ELISA Kits (DIAPH1)
On are 1 Diaphanous Homolog 1 (Drosophila) (DIAPH1) ELISA Kits from 1 different suppliers available. Additionally we are shipping DIAPH1 Antibodies (63) and DIAPH1 Proteins (5) and many more products for this protein. A total of 75 DIAPH1 products are currently listed.
D18Wsu154e, DFNA1, DIA1, Diap1, Diaph1, DIAPH2, DRF1, hDIA1, LFHL1, mKIAA4062, p140mDia
list all ELISA KIts Gene Name GeneID UniProt
Rat DIAPH1 DIAPH1 307483  
Mouse DIAPH1 DIAPH1 13367 O08808
DIAPH1 1729 O60610

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More ELISA Kits for DIAPH1 Interaction Partners

Mouse (Murine) Diaphanous Homolog 1 (Drosophila) (DIAPH1) interaction partners

  1. Small Molecule Inhibition of Ligand-Stimulated RAGE (show AGER ELISA Kits)-DIAPH1 Signal Transduction.

  2. Diaphanous-related formin (show DIAPH3 ELISA Kits) signaling plays a role in heart and vascular development and the maintenance of SMC (show DYM ELISA Kits) phenotype.

  3. Liprin-alpha3 (show PPFIA3 ELISA Kits) uses an alpha-helical region to bind to mDia1, counteracting mouse Dia1 (show CYB5R3 ELISA Kits) activation by RhoA (show RHOA ELISA Kits).

  4. Depleting FMNL1 (show FMNL1 ELISA Kits), another Formin (show FMN1 ELISA Kits) family member, resulted in reduced mDia1 expression, while RhoA (show RHOA ELISA Kits) inhibition did not alter mDia1 expression, which indicated that there was a FMNL1 (show FMNL1 ELISA Kits)-mDia1-Profilin1 (show PFN1 ELISA Kits) signaling pathway in mouse oocytes.

  5. Mechanistically, mDia1 deficiency led to a downregulation of membrane-associated genes and a specific upregulation of CD14 (show CD14 ELISA Kits) messenger RNA in granulocytes, but not in other lineages.

  6. Mammalian diaphanous-related formin 1 regulates GSK3beta (show GSK3b ELISA Kits)-dependent microtubule dynamics required for T cell migratory polarization.

  7. mDia1 can efficiently put actin filaments under mechanical tension.

  8. The active form of mDia1 localized to the apical membrane in exocrine pancreas cells; introduction of an active form of mDia1 leads to a marked increase in actin bundle density along the secretory vesicle lumen perimeter.

  9. Dia1 (show CYB5R3 ELISA Kits) and Dia2 (show DIAPH3 ELISA Kits) are dynamic components of meiotic spindle and pole complex during meiotic maturation of oocytes.

  10. Actin-capping protein is a novel regulator of microtubule stability that functions by antagonizing mDia1 activity toward actin filaments.

Human Diaphanous Homolog 1 (Drosophila) (DIAPH1) interaction partners

  1. The authors describe a novel patient-derived DIAPH1 mutation (c.3610C>T) in two unrelated families, which results in early termination prior to a basic amino acid motif (RRKR(1204-1207)) at the DAD C-terminus. The mutant DIA1 (show CYB5R3 ELISA Kits)(R1204X) disrupted the autoinhibitory DID-DAD interaction and was constitutively active.

  2. The description of a novel disorder of platelet formation and hearing loss extends the repertoire of DIAPH1-related disease, and provides new insight into the autoregulation of DIAPH1 activity.

  3. Studies indicate that diaphanous related formin 1 (DIAPH1) is essentially involved in microtubules (MTs (show TIMM8A ELISA Kits))-dependent early adhesion of colon cancer cells.

  4. A 51-year-old patient in a Korean family with ADNSHL was examined by pure-tone audiometry, and genetic analysis of DIAPH1 was performed. A novel variant, p.I530S (c.1589T > G), was identified in the DIAPH1 gene, and the mutation was located in the highly conserved coiled-coil domain of the DIA1 (show CYB5R3 ELISA Kits) protein.

  5. mDia1 is an important regulator of breast cancer cell invasion and that its effects may be mediated by MMP-2 (show MMP2 ELISA Kits) activity.

  6. Findings suggest that regulation of cellular trafficking and microtubule-mediated localization of MT1-MMP (show MMP14 ELISA Kits) by mDia1 is likely important in breast cancer invasion through the expression of cancer stem cell genes.

  7. Loss-of-function variants in DIAPH1 is associated with syndromic microcephaly, blindness, and early onset seizures.

  8. functional complementation experiments and optogenetics to show that mDia1 cooperates with the Arp2 (show ACTR2 ELISA Kits)/3 complex in initiating lamellipodia and ruffles.

  9. Capping protein and dia1 (show CYB5R3 ELISA Kits) functionally coregulate filament barbed-end assembly.

  10. mDia1 displaced from the barbed end by CapZ Actin Capping Protein can randomly slide along the actin filament and later return.

DIAPH1 Antigen Profile

Antigen Summary

This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alternative names and synonyms associated with DIAPH1

  • diaphanous homolog 1 (Drosophila) (DIAPH1) Elisa Kit
  • diaphanous-related formin 1 (DIAPH1) Elisa Kit
  • diaphanous-related formin 1 (diaph1) Elisa Kit
  • diaphanous-related formin 1 (Diaph1) Elisa Kit
  • diaphanous homolog 1 (Drosophila) (diaph1) Elisa Kit
  • diaphanous homolog 1 (Drosophila) (Diap1) Elisa Kit
  • D18Wsu154e Elisa Kit
  • DFNA1 Elisa Kit
  • DIA1 Elisa Kit
  • Diap1 Elisa Kit
  • Diaph1 Elisa Kit
  • DIAPH2 Elisa Kit
  • DRF1 Elisa Kit
  • hDIA1 Elisa Kit
  • LFHL1 Elisa Kit
  • mKIAA4062 Elisa Kit
  • p140mDia Elisa Kit

Protein level used designations for DIAPH1

diaphanous homolog 1 (Drosophila) , diaphanous homolog 1 , diaphanous homolog 2 , protein diaphanous homolog 1 , protein diaphanous homolog 1-like , diaphanous-related formin-1 , mDIA1

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374040 Gallus gallus
307483 Rattus norvegicus
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100562222 Anolis carolinensis
13367 Mus musculus
1729 Homo sapiens
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