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DIAPH1 Products

(Diaphanous Homolog 1 (DIAPH1))

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This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured DIAPH1 Categories

DIAPH1 Antibodies

High quality antibodies with extensive validation data.

DIAPH1 ELISA Kits

Reliable ELISA kits for a wide range of species.

DIAPH1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DIAPH1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application ICC, IF, IHC (p), WB
Validations
  • (4)
Cat. No. ABIN2855273
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ICC, IF, IHC (p), WB
Validations
  • (3)
Cat. No. ABIN2855266
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Rat
Application IHC, WB
Validations
  • (3)
Cat. No. ABIN6263174
Quantity 100 μL
Datasheet Datasheet

Recommended DIAPH1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955376
Quantity 96 tests
Datasheet Datasheet

Recommended DIAPH1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3092158
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3131322
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351590
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our DIAPH1 products

Colón-Franco, Gomez, Billadeau: "Dynamic remodeling of the actin cytoskeleton by FMNL1γ is required for structural maintenance of the Golgi complex." in: Journal of cell science, Vol. 124, Issue Pt 18, pp. 3118-26, (2011) (PubMed).

Goel, Sienkiewicz, Picciani, Lee, Bhattacharya: "Cochlin induced TREK-1 co-expression and annexin A2 secretion: role in trabecular meshwork cell elongation and motility." in: PLoS ONE, Vol. 6, Issue 8, pp. e23070, (2011) (PubMed).

Ryu, Echarri, Li, Pendergast: "Regulation of cell-cell adhesion by Abi/Diaphanous complexes." in: Molecular and cellular biology, Vol. 29, Issue 7, pp. 1735-48, (2009) (PubMed).

Lartey, Smith, Pawade, Strachan, Mellor, López Bernal: "Up-regulation of myometrial RHO effector proteins (PKN1 and DIAPH1) and CPI-17 (PPP1R14A) phosphorylation in human pregnancy is associated with increased GTP-RHOA in spontaneous preterm labor." in: Biology of reproduction, Vol. 76, Issue 6, pp. 971-82, (2007) (PubMed).

Sakata, Taniguchi, Yasuda, Adachi-Morishima, Hamazaki, Nakayama, Miki, Minato, Narumiya: "Impaired T lymphocyte trafficking in mice deficient in an actin-nucleating protein, mDia1." in: The Journal of experimental medicine, Vol. 204, Issue 9, pp. 2031-8, (2007) (PubMed).

Minin, Kulik, Gyoeva, Li, Goshima, Gelfand: "Regulation of mitochondria distribution by RhoA and formins." in: Journal of cell science, Vol. 119, Issue Pt 4, pp. 659-70, (2006) (PubMed).

Jewett, Fischer, Mead, Hackstadt: "Chlamydial TARP is a bacterial nucleator of actin." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 42, pp. 15599-604, (2006) (PubMed).

Li, Higgs: "The mouse Formin mDia1 is a potent actin nucleation factor regulated by autoinhibition." in: Current biology : CB, Vol. 13, Issue 15, pp. 1335-40, (2003) (PubMed).

Pennisi: "The architecture of hearing." in: Science (New York, N.Y.), Vol. 278, Issue 5341, pp. 1223-4, (1997) (PubMed).

Watanabe, Madaule, Reid, Ishizaki, Watanabe, Kakizuka, Saito, Nakao, Jockusch, Narumiya: "p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin." in: The EMBO journal, Vol. 16, Issue 11, pp. 3044-56, (1997) (PubMed).

Synonyms and alternative names related to DIAPH1

diaphanous related formin 1 (DIAPH1), diaphanous related formin 1 (diaph1), diaphanous related formin 2 (DIAPH2), diaphanous-related formin 1 (Diaph1), protein diaphanous homolog 1 (LOC100457442), diaphanous related formin 1 (Diaph1), D18Wsu154e, dfna1, DFNA1, dia1, Dia1, DIA1, diap1, Diap1, DIAPH1, Diaph1, DIAPH2, drf1, Drf1, DRF1, hDIA1, lfhl1, LFHL1, mKIAA4062, p140mDia

Protein level used designations for DIAPH1

  • diaphanous homolog 1 (Drosophila)
  • diaphanous homolog 1
  • diaphanous homolog 2
  • protein diaphanous homolog 1
  • protein diaphanous homolog 1-like
  • diaphanous-related formin-1
  • mDIA1
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