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Browse our anti-POU4F3 (POU4F3) Antibodies

Full name:
anti-POU Domain, Class 4, Transcription Factor 3 Antibodies (POU4F3)
On www.antibodies-online.com are 62 POU Domain, Class 4, Transcription Factor 3 (POU4F3) Antibodies from 16 different suppliers available. Additionally we are shipping POU4F3 Proteins (5) and many more products for this protein. A total of 77 POU4F3 products are currently listed.
Synonyms:
BRN-3, BRN-3.1, brn-3c, BRN3, Brn3.1, Brn3c, ddl, DFNA15, dreidel, POU4F3
list all antibodies Gene Name GeneID UniProt
POU4F3 5459 Q15319
POU4F3 364855  
POU4F3 18998 Q63955

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Most Popular Reactivities for anti-POU4F3 (POU4F3) Antibodies

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anti-Human POU4F3 Antibodies:

anti-Rat (Rattus) POU4F3 Antibodies:

anti-Mouse (Murine) POU4F3 Antibodies:

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Top referenced anti-POU4F3 Antibodies

  1. Chicken Polyclonal POU4F3 Primary Antibody for IHC, WB - ABIN2777732 : Weiss, Meeks, Hurley, Raverot, Frassetto, Jameson: Sox3 is required for gonadal function, but not sex determination, in males and females. in Molecular and cellular biology 2003 (PubMed)
    Show all 2 references for ABIN2777732

  2. Human Polyclonal POU4F3 Primary Antibody for ELISA, WB - ABIN4346890 : van Drunen, Pauw, Collin, Kremer, Huygen, Cremers: Vestibular impairment in a Dutch DFNA15 family with an L289F mutation in POU4F3. in Audiology & neuro-otology 2009 (PubMed)

  3. Human Polyclonal POU4F3 Primary Antibody for ELISA, WB - ABIN1450968 : Vahava, Morell, Lynch, Weiss, Kagan, Ahituv, Morrow, Lee, Skvorak, Morton, Blumenfeld, Frydman, Friedman, King, Avraham: Mutation in transcription factor POU4F3 associated with inherited progressive hearing loss in humans. in Science (New York, N.Y.) 1998 (PubMed)

More Antibodies against POU4F3 Interaction Partners

Human POU Domain, Class 4, Transcription Factor 3 (POU4F3) interaction partners

  1. This study showed that Mendelian sensorineural hearing loss exhibits vestibular dysfunction, including DFNA9 (show COCH Antibodies), DFNA11 (show MYO7A Antibodies), DFNA15 and DFNA28 (show GRHL2 Antibodies).

  2. The pou4f3 gene is regulated by ATOH1 (show ATOH1 Antibodies) and other transcription factors in cochlear hair cells.

  3. These data demonstrate that Nr2f2 (show NR2F1 Antibodies) is a direct target of POU4F3 in vitro and that this regulatory relationship may be relevant to hair cell development and survival.

  4. new variants in genes such as POU4F3 is associated with nonsyndromic deafness and vestibular dysfunction

  5. SNP linkage analysis and whole exome sequencing identify a novel POU4F3 mutation in autosomal dominant late-onset nonsyndromic hearing loss (DFNA15).

  6. This is the first report of a POU4F3 mutation in Asia, and moreover our data suggest that further investigation will need to delineate ethnicity-specific genetic background for autosomal dominant non-syndromic hearing loss within Asian populations.

  7. Mutant POU4F3 loses most of its transcriptional activity and most of its ability to bind to DNA. The mutation causes autosomal-dominant nonsyndromic hearing loss and eventually leads to hair cell morbidity in affected family H members.

  8. Data show that Brn-3c is capable of activating both BDNF (show BDNF Antibodies) and NT-3 (show NTF3 Antibodies) promoters in inner ear sensory epithelial cell lines.

  9. our data show there are common sequence variants in the Brn-3c 5'-flanking region that affect transcriptional regulation in vitro

  10. Mutation analysis of the POU4F3 gene in 30 patients suffering from dominantly inherited hearing impairment revealed a second novel missense mutation (c.668T>C).

Mouse (Murine) POU Domain, Class 4, Transcription Factor 3 (POU4F3) interaction partners

  1. These data demonstrate that Nr2f2 (show NR2F2 Antibodies) is a direct target of POU4F3 in vitro and that this regulatory relationship may be relevant to hair cell development and survival.

  2. Data indicate that Brn3 (show POU4F1 Antibodies) transcription factors Brn3b (show POU4F2 Antibodies) affects Brn3a (show POU4F1 Antibodies) and Brn3c positive Retinal Ganglion Cells (RGCs) in cell autonomous and non-cell autonomous fashion.

  3. induction of POU4F3 by TFE2 and GATA3 (show GATA3 Antibodies)

  4. neither Brn3a (show POU4F1 Antibodies) nor Brn3c are expressed in intrinsically photosensitive retinal ganglion cells

  5. Data show that Ap-2delta occupies and activates the Pou4f3 and Bhlhb4 (show BHLHE23 Antibodies) promoters.

  6. Stress-granule-associated protein Caprin-1 is downregulated by Pou4f3.

  7. Taken together, our data suggest that SHH (show SHH Antibodies) plays an important role in the promotion of auditory hair cell differentiation via the Math1 (show ATOH1 Antibodies)-Brn3.1 signaling pathway.

  8. Brn3c null mice show severe compromised production of these neurotrophins and should therefore show a comparable pattern of nerve fiber loss.

  9. Brn-3c was found to contain an independent N-terminal activation domain that is sufficient to activate gene transcription in the organ-of-Corti-derived cell lines.

  10. Inner hair cells constitutively express alpha9alpha10 nicotinic cholinergic receptors into adulthood by expressing the alpha10 cDNA under the control of the Pou4f3 gene promoter.

POU4F3 Antigen Profile

Antigen Summary

This gene encodes a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. This protein is found in the retina and may play a role in determining or maintaining the identities of a small subset of visual system neurons. Defects in this gene are the cause of non-syndromic sensorineural deafness autosomal dominant type 15.

Alternative names and synonyms associated with POU4F3

  • POU class 4 homeobox 3 (POU4F3) antibody
  • POU class 4 homeobox 3 (Pou4f3) antibody
  • POU domain, class 4, transcription factor 3 (pou4f3) antibody
  • POU domain, class 4, transcription factor 3 (Pou4f3) antibody
  • BRN-3 antibody
  • BRN-3.1 antibody
  • brn-3c antibody
  • BRN3 antibody
  • Brn3.1 antibody
  • Brn3c antibody
  • ddl antibody
  • DFNA15 antibody
  • dreidel antibody
  • POU4F3 antibody

Protein level used designations for POU4F3

POU class 4 homeobox 3 , POU domain, class 4, transcription factor 3 , brain-3 , brain-specific homeobox/POU domain protein 3 , brain-3C , brain-specific homeobox/POU domain protein 3C , brn-3C , brain POU domain gene 3.1 , brain-3.1 , brain-specific homeobox/POU domain protein 3.1 , zfbrn-3.1 , brain-specific homeobox POU domain protein 3C

GENE ID SPECIES
471685 Pan troglodytes
395521 Gallus gallus
5459 Homo sapiens
487200 Canis lupus familiaris
100510953 Sus scrofa
538520 Bos taurus
364855 Rattus norvegicus
30534 Danio rerio
18998 Mus musculus
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