Browse our anti-EPAS1 (EPAS1) Antibodies

Full name:
anti-Endothelial PAS Domain Protein 1 Antibodies (EPAS1)
On www.antibodies-online.com are 219 Endothelial PAS Domain Protein 1 (EPAS1) Antibodies from 22 different suppliers available. Additionally we are shipping EPAS1 Kits (21) and EPAS1 Proteins (10) and many more products for this protein. A total of 257 EPAS1 products are currently listed.
Synonyms:
bhlhe73, ecyt4, EPAS, EPAS-1, EPAS1, HIF-2alpha, hif2, hif2a, hif2alpha, hlf, HRF, mop2, pasd2
list all antibodies Gene Name GeneID UniProt
EPAS1 2034 Q99814
EPAS1 13819 P97481
EPAS1 29452 Q9JHS1

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Top referenced anti-EPAS1 Antibodies

  1. Fish Polyclonal EPAS1 Primary Antibody for ChIP, ELISA - ABIN151051 : Conrad, Freeman, Beitner-Johnson, Millhorn: EPAS1 trans-activation during hypoxia requires p42/p44 MAPK. in The Journal of biological chemistry 1999 (PubMed)
    Show all 478 references for 151051

  2. Hamster Monoclonal EPAS1 Primary Antibody for ChIP, ELISA - ABIN151063 : Bernhardt, Wiesener, Weidemann, Schmitt, Weichert, Lechler, Campean, Ong, Willam, Gretz, Eckardt: Involvement of hypoxia-inducible transcription factors in polycystic kidney disease. in The American journal of pathology 2007 (PubMed)
    Show all 146 references for 151063

  3. Hamster Monoclonal EPAS1 Primary Antibody for ELISA, IHC - ABIN250056 : Harvey, Kind, Pantaleon, Armstrong, Thompson: Oxygen-regulated gene expression in bovine blastocysts. in Biology of reproduction 2004 (PubMed)
    Show all 19 references for 250056

  4. Hamster Monoclonal EPAS1 Primary Antibody for ELISA, ICC - ABIN250055 : Mekhail, Gunaratnam, Bonicalzi, Lee: HIF activation by pH-dependent nucleolar sequestration of VHL. in Nature cell biology 2004 (PubMed)
    Show all 15 references for 250055

  5. Human Monoclonal EPAS1 Primary Antibody for AA, ELISA - ABIN863099 : Kim, Perera, Zhou, Carretero, Yeh, Heathcote, Jackson, Nikolinakos, Ospina, Naumov, Brandstetter, Weigman, Zaghlul, Hayes, Padera, Heymach, Kung, Sharpless, Kaelin, Wong: HIF2alpha cooperates with RAS to promote lung tumorigenesis in mice. in The Journal of clinical investigation 2009 (PubMed)
    Show all 4 references for 863099

  6. Human Polyclonal EPAS1 Primary Antibody for EIA, FACS - ABIN952733 : Yi, Liang, Huerta-Sanchez, Jin, Cuo, Pool, Xu, Jiang, Vinckenbosch, Korneliussen, Zheng, Liu, He, Li, Luo, Nie, Wu, Zhao, Cao, Zou, Shan, Li, Yang, Asan, Ni, Tian, Xu, Liu, Jiang, Wu, Zhou, Tang, Qin, Wang, Feng, Li, Huasang, Luosang, Wang, Chen, Wang, Zh: Sequencing of 50 human exomes reveals adaptation to high altitude. in Science (New York, N.Y.) 2010 (PubMed)
    Show all 2 references for 952733

  7. Human Polyclonal EPAS1 Primary Antibody for FACS, WB - ABIN654664 : Bougatef, Menashi, Khayati, Naïmi, Porcher, Podgorniak, Millot, Janin, Calvo, Lebbé, Mourah: EMMPRIN promotes melanoma cells malignant properties through a HIF-2alpha mediated up-regulation of VEGF-receptor-2. in PLoS ONE 2010 (PubMed)
    Show all 2 references for 654664

  8. Human Polyclonal EPAS1 Primary Antibody for WB - ABIN658111 : Mowat, Luhmann, Smith, Lange, Duran, Harten, Shukla, Maxwell, Ali, Bainbridge: HIF-1alpha and HIF-2alpha are differentially activated in distinct cell populations in retinal ischaemia. in PLoS ONE 2010 (PubMed)
    Show all 2 references for 658111

  9. Human Polyclonal EPAS1 Primary Antibody for IF (p), IHC (p) - ABIN686662 : Li, Chen, Shao, Tang, Chen, Chen, Xu: Oxidative stress induces the decline of brain EPO expression in aging rats. in Experimental gerontology 2016 (PubMed)

  10. Cow (Bovine) Polyclonal EPAS1 Primary Antibody for WB - ABIN2779523 : Koizume, Yokota, Miyagi, Hirahara, Tsuchiya, Miyagi: Heterogeneity in binding and gene-expression regulation by HIF-2alpha. in Biochemical and biophysical research communications 2008 (PubMed)

More Antibodies against EPAS1 Interaction Partners

Human Endothelial PAS Domain Protein 1 (EPAS1) interaction partners

  1. Findings show that hypoxia inducible factor 1 alpha subunit (HIF-1alpha (show HIF1A Antibodies)) is phylogenetically conserved among most metazoans, whereas HIF-2alpha protein appeared later.

  2. proteomic experiments on Normoxic Neuroblastoma (show ARHGEF16 Antibodies) cells to investigate HIF-2alpha downstream-regulated proteins or pathways

  3. HIF1A (show HIF1A Antibodies) and HIF2A contribute to cancer stem cells survival but play different roles -HIF1A (show HIF1A Antibodies) being more responsible for survival functions and HIF2A for self-renewal [review].

  4. The negative feedback modulation between LncRNA-SARCC/AR complex and HIF-2alpha signaling may then lead to differentially modulated RCC (show XRCC1 Antibodies) progression in a VHL (show VHL Antibodies)-dependent manner. Together, these results may provide us a new therapeutic approach via targeting this newly identified signal from LncRNA-SARCC to AR-mediated HIF-2alpha/C-MYC (show MYC Antibodies) signals against RCC (show XRCC1 Antibodies) progression.

  5. Results suggested that the oncogenic transcription factor HIF-2alpha stabilized VHL (show VHL Antibodies) disease suppressor B-Myb (show MYBL2 Antibodies), which is also a transcription factor, by physical interaction. Some B-Myb (show MYBL2 Antibodies)-dependent gene expression was similarly affected by B-Myb (show MYBL2 Antibodies) or HIF-2alpha knockdown, suggesting that stabilization of B-Myb (show MYBL2 Antibodies) by HIF-2alpha may play a role in specific gene expressions.

  6. Data suggest a common mechanism by which DNA methyltransferase1 (DNMT1 (show DNMT1 Antibodies)) and hypoxia inducible factors HIF1alpha (show HIF1A Antibodies)/HIF2alpha regulate Sprouty2 (Spry2 (show SPRY2 Antibodies)) transcription.

  7. Hypoxia microenvironment in hepatocellular carcinoma up-regulates HIF2/SCF (show KITLG Antibodies) expression, which in turn promotes angiogenesis and HCC (show FAM126A Antibodies) metastasis.

  8. CK1delta enhances EPO (show EPO Antibodies) secretion from liver cancer cells under hypoxia by modifying HIF-2alpha and promoting its nuclear accumulation.

  9. LOX (show LOX Antibodies), a hypoxia-responsive gene that encodes lysyl oxidase (show LOX Antibodies), is activated by HIF-2-alpha more than HIF-1 (show HIF1A Antibodies). Two new hypoxia response elements identified in the LOX (show LOX Antibodies) promoter mediate most HIF responsiveness.

  10. Our results indicate that HPV16 E6/E7 indirectly upregulated the expression of VEGF by inhibition of liver kinase B1 expression and upregulation of hypoxia-inducible factor 2alpha expression,thus propose a human papillomavirus-liver kinase B1-hypoxia-inducible factor 2A-vascular endothelial growth factor axis for the tumorigenesis of lung cancer

Mouse (Murine) Endothelial PAS Domain Protein 1 (EPAS1) interaction partners

  1. this study shows that HIF-2alpha acts in resting macrophages as a phagocytosis suppressor implying an important relationship between the levels of HIF-2alpha and susceptibility to infection

  2. in neurons HIF-1 (show HIF1A Antibodies) and HIF-2 have redundant functions for cellular survival under ischemic conditions. By contrast, lack of anti-survival factors in Hif1a (show HIF1A Antibodies)/Hif2a-deficient mice might protect from early acute neuronal cell death and neurological impairment, indicating a benefit of HIF-pathway inhibition in neurons in the very acute phase after ischemic stroke

  3. HIF-2alpha is a novel regulator of neutrophil recruitment to colon tumors.

  4. AQP1 (show AQP1 Antibodies) deficiency delays long-term ischemia-reperfusion resolution, partly through repressing angiogenesis mediated by destabilizing HIF-2alpha.

  5. HIF1alpha (show HIF1A Antibodies) and HIF2alpha are dispensable for muscle stem cell function under normoxia but are required for maintaining satellite cell self-renewal in hypoxic environments.

  6. eIF3e (show EIF3E Antibodies) is an angiogenesis suppressor. Silencing of eIF3e (show EIF3E Antibodies) promotes blood perfusion recovery after limb ischemia through stabilization of hypoxia-inducible factor 2alpha activity.

  7. The regulatory connection between HIF-2alpha and VEGFR-1 (show FLT1 Antibodies), VEGFR-2 (show KDR Antibodies) and MMP2 (show MMP2 Antibodies).

  8. HIF2alpha is essential for the acute postprandial regulation of hepatic glucagon (show GCG Antibodies) signaling.

  9. demonstrate that HIF-2alpha is clearly implicated in the TSP1 (show GZMA Antibodies) pulmonary regulation and provide new insights on its contribution to pulmonary arterial hypertension-driven vascular remodelling and vasoconstriction

  10. Findings identify a reciprocal activation mechanism involving HIF-2alpha and the zinc-ZIP8 (show SLC39A8 Antibodies)-MTF1 (show MTF1 Antibodies) axis during osteoarthritis pathogenesis that amplifies catabolic signaling and cartilage destruction.

Pig (Porcine) Endothelial PAS Domain Protein 1 (EPAS1) interaction partners

  1. immunostaining for HIF-1alpha (show HIF1A Antibodies) and HIF-2alpha was observed during endochondral ossification; only HIF-2alpha was present at sites of intramembranous ossification

Cow (Bovine) Endothelial PAS Domain Protein 1 (EPAS1) interaction partners

  1. There was an association of an EPAS1 (HIF2alpha) double variant in the oxygen degradation domain of EPAS1 in Angus cattle with high altitude pulmonary hypertension (HAPH). There was upregulation of 26 of 27 HIF2alpha target genes in EPAS1 carriers with HAPH.

EPAS1 Antigen Profile

Antigen Summary

This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.

Alternative names and synonyms associated with EPAS1

  • endothelial PAS domain protein 1 (EPAS1) antibody
  • endothelial PAS domain protein 1 (epas1) antibody
  • endothelial PAS domain protein 1 (Epas1) antibody
  • bhlhe73 antibody
  • ecyt4 antibody
  • EPAS antibody
  • EPAS-1 antibody
  • EPAS1 antibody
  • HIF-2alpha antibody
  • hif2 antibody
  • hif2a antibody
  • hif2alpha antibody
  • hlf antibody
  • HRF antibody
  • mop2 antibody
  • pasd2 antibody

Protein level used designations for EPAS1

endothelial PAS domain protein 1 , endothelial PAS domain-containing protein 1-like , EPAS-1 , HIF-1-alpha-like factor , HIF-1alpha-like factor , HIF-2-alpha , HIF2-alpha , PAS domain-containing protein 2 , basic-helix-loop-helix-PAS protein MOP2 , class E basic helix-loop-helix protein 73 , endothelial PAS domain-containing protein 1 , hypoxia-inducible factor 2 alpha , hypoxia-inducible factor 2-alpha , member of PAS protein 2 , HIF-related factor , HIF1 alpha-like factor , HIF1alpha-like factor , HLF (HIF1alpha-like factor) , Hif like protein , hypoxia inducible transcription factor 2alpha , mHLF , HIF-2 alpha , HIF2 alpha , hypoxia inducible factor 2, alpha subunit , hypoxia inducible factor 2a , HIF-2alpha

GENE ID SPECIES
459204 Pan troglodytes
714641 Macaca mulatta
100220014 Taeniopygia guttata
100396711 Callithrix jacchus
100439667 Pongo abelii
100543912 Meleagris gallopavo
100551891 Anolis carolinensis
100606638 Nomascus leucogenys
2034 Homo sapiens
13819 Mus musculus
29452 Rattus norvegicus
444145 Xenopus laevis
395596 Gallus gallus
474578 Canis lupus familiaris
100037272 Sus scrofa
282711 Bos taurus
100068622 Equus caballus
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