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Browse our anti-EPAS1 (EPAS1) Antibodies

Full name:
anti-Endothelial PAS Domain Protein 1 Antibodies (EPAS1)
On are 213 Endothelial PAS Domain Protein 1 (EPAS1) Antibodies from 22 different suppliers available. Additionally we are shipping EPAS1 Kits (18) and EPAS1 Proteins (10) and many more products for this protein. A total of 248 EPAS1 products are currently listed.
bhlhe73, ecyt4, EPAS, EPAS-1, EPAS1, HIF-2alpha, hif2, hif2a, hif2alpha, hlf, HRF, mop2, pasd2
list all antibodies Gene Name GeneID UniProt
EPAS1 2034 Q99814
EPAS1 13819 P97481
EPAS1 29452 Q9JHS1

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All available anti-EPAS1 Antibodies

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Top referenced anti-EPAS1 Antibodies

  1. Fish Polyclonal EPAS1 Primary Antibody for ChIP, ELISA - ABIN151051 : Conrad, Freeman, Beitner-Johnson, Millhorn: EPAS1 trans-activation during hypoxia requires p42/p44 MAPK. in The Journal of biological chemistry 1999 (PubMed)
    Show all 470 references for ABIN151051

  2. Hamster Monoclonal EPAS1 Primary Antibody for ChIP, ELISA - ABIN151063 : Bernhardt, Wiesener, Weidemann, Schmitt, Weichert, Lechler, Campean, Ong, Willam, Gretz, Eckardt: Involvement of hypoxia-inducible transcription factors in polycystic kidney disease. in The American journal of pathology 2007 (PubMed)
    Show all 145 references for ABIN151063

  3. Hamster Monoclonal EPAS1 Primary Antibody for ELISA, IHC - ABIN250056 : Harvey, Kind, Pantaleon, Armstrong, Thompson: Oxygen-regulated gene expression in bovine blastocysts. in Biology of reproduction 2004 (PubMed)
    Show all 19 references for ABIN250056

  4. Hamster Monoclonal EPAS1 Primary Antibody for ELISA, ICC - ABIN250055 : Mekhail, Gunaratnam, Bonicalzi, Lee: HIF activation by pH-dependent nucleolar sequestration of VHL. in Nature cell biology 2004 (PubMed)
    Show all 15 references for ABIN250055

  5. Human Monoclonal EPAS1 Primary Antibody for AA, ELISA - ABIN863099 : Kim, Perera, Zhou, Carretero, Yeh, Heathcote, Jackson, Nikolinakos, Ospina, Naumov, Brandstetter, Weigman, Zaghlul, Hayes, Padera, Heymach, Kung, Sharpless, Kaelin, Wong: HIF2alpha cooperates with RAS to promote lung tumorigenesis in mice. in The Journal of clinical investigation 2009 (PubMed)
    Show all 4 references for ABIN863099

  6. Human Polyclonal EPAS1 Primary Antibody for EIA, FACS - ABIN952733 : Yi, Liang, Huerta-Sanchez, Jin, Cuo, Pool, Xu, Jiang, Vinckenbosch, Korneliussen, Zheng, Liu, He, Li, Luo, Nie, Wu, Zhao, Cao, Zou, Shan, Li, Yang, Asan, Ni, Tian, Xu, Liu, Jiang, Wu, Zhou, Tang, Qin, Wang, Feng, Li, Huasang, Luosang, Wang, Chen, Wang, Zh: Sequencing of 50 human exomes reveals adaptation to high altitude. in Science (New York, N.Y.) 2010 (PubMed)
    Show all 2 references for ABIN952733

  7. Human Polyclonal EPAS1 Primary Antibody for WB - ABIN658111 : Bougatef, Menashi, Khayati, Naïmi, Porcher, Podgorniak, Millot, Janin, Calvo, Lebbé, Mourah: EMMPRIN promotes melanoma cells malignant properties through a HIF-2alpha mediated up-regulation of VEGF-receptor-2. in PLoS ONE 2010 (PubMed)
    Show all 2 references for ABIN658111

  8. Human Polyclonal EPAS1 Primary Antibody for FACS, WB - ABIN654664 : Mowat, Luhmann, Smith, Lange, Duran, Harten, Shukla, Maxwell, Ali, Bainbridge: HIF-1alpha and HIF-2alpha are differentially activated in distinct cell populations in retinal ischaemia. in PLoS ONE 2010 (PubMed)
    Show all 2 references for ABIN654664

  9. Cow (Bovine) Polyclonal EPAS1 Primary Antibody for WB - ABIN2779523 : Koizume, Yokota, Miyagi, Hirahara, Tsuchiya, Miyagi: Heterogeneity in binding and gene-expression regulation by HIF-2alpha. in Biochemical and biophysical research communications 2008 (PubMed)

  10. Human Polyclonal EPAS1 Primary Antibody for IF (p), IHC (p) - ABIN686662 : Li, Chen, Shao, Tang, Chen, Chen, Xu: Oxidative stress induces the decline of brain EPO expression in aging rats. in Experimental gerontology 2016 (PubMed)

More Antibodies against EPAS1 Interaction Partners

Human Endothelial PAS Domain Protein 1 (EPAS1) interaction partners

  1. The advantageous Tibetan EPAS1 haplotype shared many variants with the Denisovan genome, with an ancient gene tree divergence between the Tibetan and Denisovan haplotypes of about 1 million years ago. With the exception of EPAS1, we observed no evidence of positive selection on Denisovan-like haplotypes

  2. there is a HIF-2alpha-MALAT1-miR (show MLXIP Antibodies)-216b axis regulating multi-drug resistance of hepatocellular carcinoma cells via modulating autophagy.

  3. eIF3e (show EIF3E Antibodies) is an angiogenesis suppressor. Silencing of eIF3e (show EIF3E Antibodies) promotes blood perfusion recovery after limb ischemia through stabilization of hypoxia-inducible factor 2alpha activity.

  4. knockdown of HIF-2-alpha in the osteosarcoma cell line reduced the proliferation of cancer cells and increased apoptosis. These effects likely occurred through the MAPKp38 signaling pathway.

  5. The von Hippel-Lindau protein (pVHL)-dependent degradation of HIF-2a participates in the regulation of ERalpha expression. Additionally, HIF-2a forms a protein complex with ERa, and amino acids 396-823 of HIF-2a physically interact with the ligand-binding domain of ERa

  6. These results suggested that HIF-2alpha may cause meniscal matrix degradation by transactivation of MMP-13 (show MMP13 Antibodies)

  7. We assessed HIF1A (show HIF1A Antibodies) and EPAS1 expression in a 4-day in vitro culture of primary term cytotrophoblasts under 21% O2 and 2.5% O2. In undifferentiated cytotrophoblasts, EPAS1 transcripts were four times more abundant than HIF1A (show HIF1A Antibodies) transcripts. EPAS1 mRNA and protein expression increased during cytotrophoblast differentiation.

  8. HIF-2alpha and HIF2PUT upregulation may be a common feature in human osteosarcomas with aggressive potency. The over-expression of the two molecules, alone or combined, may predict poor prognosis in osteosarcoma patients.

  9. High HIF2A expression is associated with gastric cancer.

  10. Overexpression of EPAS1 is associated with neoplasms.

Mouse (Murine) Endothelial PAS Domain Protein 1 (EPAS1) interaction partners

  1. HIF1alpha (show HIF1A Antibodies) and HIF2alpha are dispensable for muscle stem cell function under normoxia but are required for maintaining satellite cell self-renewal in hypoxic environments.

  2. eIF3e (show EIF3E Antibodies) is an angiogenesis suppressor. Silencing of eIF3e (show EIF3E Antibodies) promotes blood perfusion recovery after limb ischemia through stabilization of hypoxia-inducible factor 2alpha activity.

  3. The regulatory connection between HIF-2alpha and VEGFR-1 (show FLT1 Antibodies), VEGFR-2 (show KDR Antibodies) and MMP2 (show MMP2 Antibodies).

  4. HIF2alpha is essential for the acute postprandial regulation of hepatic glucagon (show GCG Antibodies) signaling.

  5. demonstrate that HIF-2alpha is clearly implicated in the TSP1 (show GZMA Antibodies) pulmonary regulation and provide new insights on its contribution to pulmonary arterial hypertension-driven vascular remodelling and vasoconstriction

  6. Findings identify a reciprocal activation mechanism involving HIF-2alpha and the zinc-ZIP8 (show SLC39A8 Antibodies)-MTF1 (show MTF1 Antibodies) axis during osteoarthritis pathogenesis that amplifies catabolic signaling and cartilage destruction.

  7. This review emphasizes that sympathetic nervous system homeostasis is dependent on a balance between HIF-2alpha and HIF-1alpha (show HIF1A Antibodies).

  8. genetic analysis suggests that tubulointerstitial cellular crosstalk modulates renal EPO (show EPO Antibodies) production under conditions of epithelial HIF activation in the kidney.

  9. Chondrocytes co-cultured with HIF-2alpha-overexpressing fibroblast-like synoviocytes exhibited upregulation of Mmp3 (show MMP3 Antibodies) and Mmp13 (show MMP13 Antibodies), which is similar to the effects induced by interleukin (IL)-6 (show IL6 Antibodies) treatment of chondrocytes.

  10. HIF-2alpha inhibits high-grade soft tissue sarcoma cell growth. Loss of HIF-2alpha promotes sarcoma proliferation and increases calcium and mTORC1 signalling in undifferentiated pleomorphic sarcoma and dedifferentiated liposarcoma.

Pig (Porcine) Endothelial PAS Domain Protein 1 (EPAS1) interaction partners

  1. immunostaining for HIF-1alpha (show HIF1A Antibodies) and HIF-2alpha was observed during endochondral ossification; only HIF-2alpha was present at sites of intramembranous ossification

Cow (Bovine) Endothelial PAS Domain Protein 1 (EPAS1) interaction partners

  1. There was an association of an EPAS1 (HIF2alpha) double variant in the oxygen degradation domain of EPAS1 in Angus cattle with high altitude pulmonary hypertension (HAPH). There was upregulation of 26 of 27 HIF2alpha target genes in EPAS1 carriers with HAPH.

EPAS1 Antigen Profile

Antigen Summary

This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.

Alternative names and synonyms associated with EPAS1

  • endothelial PAS domain protein 1 (EPAS1) antibody
  • endothelial PAS domain protein 1 (epas1) antibody
  • endothelial PAS domain protein 1 (Epas1) antibody
  • bhlhe73 antibody
  • ecyt4 antibody
  • EPAS antibody
  • EPAS-1 antibody
  • EPAS1 antibody
  • HIF-2alpha antibody
  • hif2 antibody
  • hif2a antibody
  • hif2alpha antibody
  • hlf antibody
  • HRF antibody
  • mop2 antibody
  • pasd2 antibody

Protein level used designations for EPAS1

endothelial PAS domain protein 1 , endothelial PAS domain-containing protein 1-like , EPAS-1 , HIF-1-alpha-like factor , HIF-1alpha-like factor , HIF-2-alpha , HIF2-alpha , PAS domain-containing protein 2 , basic-helix-loop-helix-PAS protein MOP2 , class E basic helix-loop-helix protein 73 , endothelial PAS domain-containing protein 1 , hypoxia-inducible factor 2 alpha , hypoxia-inducible factor 2-alpha , member of PAS protein 2 , HIF-related factor , HIF1 alpha-like factor , HIF1alpha-like factor , HLF (HIF1alpha-like factor) , Hif like protein , hypoxia inducible transcription factor 2alpha , mHLF , HIF-2 alpha , HIF2 alpha , hypoxia inducible factor 2, alpha subunit , hypoxia inducible factor 2a , HIF-2alpha

459204 Pan troglodytes
714641 Macaca mulatta
100220014 Taeniopygia guttata
100396711 Callithrix jacchus
100439667 Pongo abelii
100543912 Meleagris gallopavo
100551891 Anolis carolinensis
100606638 Nomascus leucogenys
2034 Homo sapiens
13819 Mus musculus
29452 Rattus norvegicus
444145 Xenopus laevis
395596 Gallus gallus
474578 Canis lupus familiaris
100037272 Sus scrofa
282711 Bos taurus
100068622 Equus caballus
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