Browse our anti-S1PR1 (S1PR1) Antibodies

Full name:
anti-Sphingosine-1-Phosphate Receptor 1 Antibodies (S1PR1)
On www.antibodies-online.com are 203 Sphingosine-1-Phosphate Receptor 1 (S1PR1) Antibodies from 29 different suppliers available. Additionally we are shipping S1PR1 Kits (26) and S1PR1 Proteins (5) and many more products for this protein. A total of 248 S1PR1 products are currently listed.
Synonyms:
AI849002, CD363, CHEDG1, D1S3362, ECGF1, EDG-1, Edg1, fd11a07, Lpb1, S1p, S1p1, wu:fd11a07, zgc:92296
list all antibodies Gene Name GeneID UniProt
S1PR1 1901 P21453
S1PR1 13609 O08530
S1PR1 29733 P48303

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anti-Human S1PR1 Antibodies:

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Top referenced anti-S1PR1 Antibodies

  1. Human Polyclonal S1PR1 Primary Antibody for WB - ABIN264982 : Liu, Wada, Yamashita, Mi, Deng, Hobson, Rosenfeldt, Nava, Chae, Lee, Liu, Hla, Spiegel, Proia: Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation. in The Journal of clinical investigation 2000 (PubMed)
    Show all 9 references for 264982

  2. Mouse (Murine) Monoclonal S1PR1 Primary Antibody for FACS, IHC - ABIN4900842 : Maeda, Seki, Kataoka, Takemoto, Utsumi, Fukunari, Sugahara, Chiba: IL-17-Producing Vγ4+ γδ T Cells Require Sphingosine 1-Phosphate Receptor 1 for Their Egress from the Lymph Nodes under Homeostatic and Inflammatory Conditions. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)
    Show all 6 references for 4900842

  3. Human Polyclonal S1PR1 Primary Antibody for EIA, IHC (p) - ABIN358616 : Dorsam, Graeler, Seroogy, Kong, Voice, Goetzl: Transduction of multiple effects of sphingosine 1-phosphate (S1P) on T cell functions by the S1P1 G protein-coupled receptor. in Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)
    Show all 5 references for 358616

  4. Human Monoclonal S1PR1 Primary Antibody for FACS - ABIN4899114 : Williams, Stilhano, To, Tran, Wong, Silva: Hypoxia augments outgrowth endothelial cell (OEC) sprouting and directed migration in response to sphingosine-1-phosphate (S1P). in PLoS ONE 2015 (PubMed)
    Show all 4 references for 4899114

  5. Mouse (Murine) Monoclonal S1PR1 Primary Antibody for FACS - ABIN4898837 : Cuenca, Romero, Sintes, Terhorst, Engel: Targeting of Ly9 (CD229) Disrupts Marginal Zone and B1 B Cell Homeostasis and Antibody Responses. in Journal of immunology (Baltimore, Md. : 1950) 2016 (PubMed)
    Show all 3 references for 4898837

  6. Human Polyclonal S1PR1 Primary Antibody for ICC, IF - ABIN4351831 : Awojoodu, Ogle, Sefcik, Bowers, Martin, Brayman, Lynch, Peirce-Cottler, Botchwey: Sphingosine 1-phosphate receptor 3 regulates recruitment of anti-inflammatory monocytes to microvessels during implant arteriogenesis. in Proceedings of the National Academy of Sciences of the United States of America 2013 (PubMed)

  7. Human Monoclonal S1PR1 Primary Antibody for FACS - ABIN4895626 : Llinàs, Lázaro, de Salort, Matesanz-Isabel, Sintes, Engel: Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry. in Immunology letters 2010 (PubMed)

More Antibodies against S1PR1 Interaction Partners

Human Sphingosine-1-Phosphate Receptor 1 (S1PR1) interaction partners

  1. Activated S1PR1 signaling regulates the production of cellular adhesion molecules by inhibiting NF- kappaB (show NFKB1 Antibodies) activation via a beta (show SUCLA2 Antibodies)-arrestin2 (show ARRB2 Antibodies)-dependent manner

  2. Model recombinant HDL (show HSD11B1 Antibodies) (rHDL) particles formed in vitro with S1P (show MBTPS1 Antibodies) incorporated into the particle initiated the internalization of S1PR1, whereas rHDL without supplemented S1P (show MBTPS1 Antibodies) did not, suggesting that S1P (show MBTPS1 Antibodies) transported in HDL (show HSD11B1 Antibodies) can selectively activate S1PR1.

  3. Blocking of S1PR activity and inhibition of S1P (show MBTPS1 Antibodies) synthesis led to decreased expression of fibrosis and tissue remodeling-related proteins in primary cultures of orbital fibroblasts derived from patients with GO.

  4. a lipid molecule repeatedly entered the receptor between the extracellular ends of TM1 (show TPM2 Antibodies) and TM7, providing important insights into the pathway of ligand entry into the S1PR1 .

  5. Mature human thymocytes rely on S1P (show MBTPS1 Antibodies)-R1 to migrate toward S1P (show MBTPS1 Antibodies). Taken in the context of murine work demonstrating that S1P (show MBTPS1 Antibodies) is required for thymocyte egress to the periphery.

  6. ApoM (show APOM Antibodies)-bound sphingosine-1-phosphate regulates adhesion molecule (show NCAM1 Antibodies) abundance, leukocyte-endothelial adhesion, and endothelial barrier function via sphingosine-1-phosphate receptor1.

  7. The S1P1,3 activation results in Akt (show AKT1 Antibodies) phosphorylation and subsequent activation of eNOS (show NOS3 Antibodies) via phosphorylation at serine(1177) and dephosphorylation at threonine(495).

  8. HDL (show HSD11B1 Antibodies)-associated ApoM (show APOM Antibodies) is anti-apoptotic by delivering sphingosine 1-phosphate to S1P1 and S1P3 (show S1PR3 Antibodies) receptors on vascular endothelium.

  9. The present high prevalence of S1PR1 overexpression warrants the consideration of testicular diffuse large B-cell lymphoma as a distinct disease subtype and suggests the potential of the S1P/S1PR1 axis as a therapeutic target.

  10. S1PR1 inhibits the apoptosis of human myeloid leukemia (show BCL11A Antibodies) cells and promotes their proliferation.

Mouse (Murine) Sphingosine-1-Phosphate Receptor 1 (S1PR1) interaction partners

  1. The study suggests that vascular leakage of albumin (show ALB Antibodies)-sized particles in ApoM (show APOM Antibodies) deficiency is S1P- and S1P1-dependent and this dependency exacerbates the response to inflammatory stimuli.

  2. The present results suggest that Fas (show FAS Antibodies)/S1P1 signaling via activation of NF-kappaB (show NFKB1 Antibodies) in osteoclast precursor cells is a key factor in the pathogenesis of rheumatoid arthritis in the temporomandibular joint.

  3. Activation of the S1P1 receptor in cardiac mast cells confers cardio-protection during cardiac mast cell degranulation.

  4. this study shows that S1P1 downregulation mirrors the strength and persistence of the TCR stimulation, limiting egress of high affinity T cells from lymph nodes

  5. After axonal damage, S1PR1 expression was decreased in retinal neurons

  6. These results indicate a role for S1P signaling in Bordetella pertussis-mediated pathology.

  7. These results suggest that S1P signaling via S1P1 in cardiomyocytes plays a previously unknown and necessary role in heart development in mice in expansion of cardiomyocyte number and ventricular compaction.

  8. Profound depletion of S1p renders both erythrocyte and platelet pools necessary for recovery during anaphylactic shock.

  9. S1P induced chemotaxis in M1 macrophages and changed cytokine production in M2 macrophages. Phagocytosis was not affected by S1P-signalling.

  10. Data indicate that forkhead box F1 (Foxf1 (show FOXF1 Antibodies)) deletion from endothelial cells decreases the abundance of sphingosine 1-phosphate receptor 1 (S1PR1).

Cow (Bovine) Sphingosine-1-Phosphate Receptor 1 (S1PR1) interaction partners

  1. Polymorphisms in promoter regions of PDHB (show PDHB Antibodies), SORBS1 (show SORBS1 Antibodies), and EDG1 genes showing marbling-associated expression changes.

  2. we detected 2 novel SNPs, referred to as g.1475435G>A and g.1471620G>T, in the 5' flanking region of the EDG1 between low-marbled and high-marbled steer groups

  3. EDG1 SNPs, although they may not be regarded as a causal mutation, may be useful for effective marker-assisted selection to increase the levels of marbling in Japanese Black beef cattle.

S1PR1 Antigen Profile

Antigen Summary

The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion.

Alternative names and synonyms associated with S1PR1

  • sphingosine-1-phosphate receptor 5a (s1pr5a) antibody
  • sphingosine-1-phosphate receptor 1 (S1PR1) antibody
  • sphingosine-1-phosphate receptor 1 (S1pr1) antibody
  • AI849002 antibody
  • CD363 antibody
  • CHEDG1 antibody
  • D1S3362 antibody
  • ECGF1 antibody
  • EDG-1 antibody
  • Edg1 antibody
  • fd11a07 antibody
  • Lpb1 antibody
  • S1p antibody
  • S1p1 antibody
  • wu:fd11a07 antibody
  • zgc:92296 antibody

Protein level used designations for S1PR1

sphingosine-1-phosphate receptor 1 , sphingosine 1-phosphate receptor 1 , endothelial differentiation, sphingolipid G-protein-coupled receptor, 1 , S1P receptor 1 , S1P receptor Edg-1 , endothelial differentiation G-protein coupled receptor 1 , sphingosine 1-phosphate receptor EDG1 , sphingosine 1-phosphate receptor Edg-1 , endothelial differentiation sphingolipid G-protein-coupled receptor 1 , lysophospholipid receptor B1 , EDG1 (Edg1) , S1P1

GENE ID SPECIES
492350 Danio rerio
100174622 Pongo abelii
424462 Gallus gallus
457063 Pan troglodytes
490138 Canis lupus familiaris
716813 Macaca mulatta
100050049 Equus caballus
1901 Homo sapiens
13609 Mus musculus
29733 Rattus norvegicus
281135 Bos taurus
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