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Browse our anti-S1PR1 (S1PR1) Antibodies

Full name:
anti-Sphingosine-1-Phosphate Receptor 1 Antibodies (S1PR1)
On are 193 Sphingosine-1-Phosphate Receptor 1 (S1PR1) Antibodies from 27 different suppliers available. Additionally we are shipping S1PR1 Kits (24) and S1PR1 Proteins (5) and many more products for this protein. A total of 236 S1PR1 products are currently listed.
AI849002, CD363, CHEDG1, D1S3362, ECGF1, EDG-1, Edg1, fd11a07, Lpb1, S1p, S1p1, wu:fd11a07, zgc:92296
list all antibodies Gene Name GeneID UniProt
S1PR1 1901 P21453
S1PR1 13609 O08530
S1PR1 29733 P48303

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anti-Human S1PR1 Antibodies:

anti-Mouse (Murine) S1PR1 Antibodies:

anti-Rat (Rattus) S1PR1 Antibodies:

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Top referenced anti-S1PR1 Antibodies

  1. Human Polyclonal S1PR1 Primary Antibody for WB - ABIN264982 : Liu, Wada, Yamashita, Mi, Deng, Hobson, Rosenfeldt, Nava, Chae, Lee, Liu, Hla, Spiegel, Proia: Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation. in The Journal of clinical investigation 2000 (PubMed)
    Show all 9 references for ABIN264982

  2. Mouse (Murine) Monoclonal S1PR1 Primary Antibody for FACS, IHC - ABIN4900842 : Maeda, Seki, Kataoka, Takemoto, Utsumi, Fukunari, Sugahara, Chiba: IL-17-Producing Vγ4+ γδ T Cells Require Sphingosine 1-Phosphate Receptor 1 for Their Egress from the Lymph Nodes under Homeostatic and Inflammatory Conditions. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)
    Show all 6 references for ABIN4900842

  3. Human Polyclonal S1PR1 Primary Antibody for EIA, IHC (p) - ABIN358616 : Dorsam, Graeler, Seroogy, Kong, Voice, Goetzl: Transduction of multiple effects of sphingosine 1-phosphate (S1P) on T cell functions by the S1P1 G protein-coupled receptor. in Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)
    Show all 5 references for ABIN358616

  4. Human Monoclonal S1PR1 Primary Antibody for FACS - ABIN4899114 : Williams, Stilhano, To, Tran, Wong, Silva: Hypoxia augments outgrowth endothelial cell (OEC) sprouting and directed migration in response to sphingosine-1-phosphate (S1P). in PLoS ONE 2015 (PubMed)
    Show all 4 references for ABIN4899114

  5. Human Polyclonal S1PR1 Primary Antibody for EIA, IHC (p) - ABIN500650 : Miyasaka, Tanaka: Lymphocyte trafficking across high endothelial venules: dogmas and enigmas. in Nature reviews. Immunology 2004 (PubMed)
    Show all 4 references for ABIN500650

  6. Mouse (Murine) Monoclonal S1PR1 Primary Antibody for FACS - ABIN4898837 : Cuenca, Romero, Sintes, Terhorst, Engel: Targeting of Ly9 (CD229) Disrupts Marginal Zone and B1 B Cell Homeostasis and Antibody Responses. in Journal of immunology (Baltimore, Md. : 1950) 2016 (PubMed)
    Show all 3 references for ABIN4898837

  7. Human Polyclonal S1PR1 Primary Antibody for ICC, IF - ABIN4351831 : Awojoodu, Ogle, Sefcik, Bowers, Martin, Brayman, Lynch, Peirce-Cottler, Botchwey: Sphingosine 1-phosphate receptor 3 regulates recruitment of anti-inflammatory monocytes to microvessels during implant arteriogenesis. in Proceedings of the National Academy of Sciences of the United States of America 2013 (PubMed)

  8. Human Monoclonal S1PR1 Primary Antibody for FACS - ABIN4895626 : Llinàs, Lázaro, de Salort, Matesanz-Isabel, Sintes, Engel: Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry. in Immunology letters 2010 (PubMed)

More Antibodies against S1PR1 Interaction Partners

Human Sphingosine-1-Phosphate Receptor 1 (S1PR1) interaction partners

  1. Mature human thymocytes rely on S1P (show MBTPS1 Antibodies)-R1 to migrate toward S1P (show MBTPS1 Antibodies). Taken in the context of murine work demonstrating that S1P (show MBTPS1 Antibodies) is required for thymocyte egress to the periphery.

  2. ApoM (show APOM Antibodies)-bound sphingosine-1-phosphate regulates adhesion molecule (show NCAM1 Antibodies) abundance, leukocyte-endothelial adhesion, and endothelial barrier function via sphingosine-1-phosphate receptor1.

  3. The S1P1,3 activation results in Akt (show AKT1 Antibodies) phosphorylation and subsequent activation of eNOS (show NOS3 Antibodies) via phosphorylation at serine(1177) and dephosphorylation at threonine(495).

  4. HDL (show HSD11B1 Antibodies)-associated ApoM (show APOM Antibodies) is anti-apoptotic by delivering sphingosine 1-phosphate to S1P1 and S1P3 (show S1PR3 Antibodies) receptors on vascular endothelium.

  5. The present high prevalence of S1PR1 overexpression warrants the consideration of testicular diffuse large B-cell lymphoma as a distinct disease subtype and suggests the potential of the S1P/S1PR1 axis as a therapeutic target.

  6. S1PR1 inhibits the apoptosis of human myeloid leukemia (show BCL11A Antibodies) cells and promotes their proliferation.

  7. These results suggest that S1P (show MBTPS1 Antibodies) signaling plays a role in cell proliferation and drug resistance in multiple myeloma, and targeting this pathway will provide a new therapeutic direction for multiple myelomamanagement.

  8. Sphingosine 1-phosphate-induced IL-8 (show IL8 Antibodies) gene expression is mainly regulated via S1PR(1), and its secretion is regulated through S1PR(2 (show S1PR2 Antibodies)) receptor subtype.

  9. multiple lines of evidence demonstrate that S1PR1 signaling sets the sensitivity of pDC (show PNKD Antibodies) amplification of IFN responses, thereby blunting pathogenic immune responses

  10. The results indicate that sphingosine 1-phosphate is involved in the migration of precursor T-cell lymphoblastic leukemia-lymphoma blasts in vitro, which is dependent on S1P1 expression.

Mouse (Murine) Sphingosine-1-Phosphate Receptor 1 (S1PR1) interaction partners

  1. After axonal damage, S1PR1 expression was decreased in retinal neurons

  2. These results indicate a role for S1P signaling in Bordetella pertussis-mediated pathology.

  3. These results suggest that S1P signaling via S1P1 in cardiomyocytes plays a previously unknown and necessary role in heart development in mice in expansion of cardiomyocyte number and ventricular compaction.

  4. Profound depletion of S1p renders both erythrocyte and platelet pools necessary for recovery during anaphylactic shock.

  5. S1P induced chemotaxis in M1 macrophages and changed cytokine production in M2 macrophages. Phagocytosis was not affected by S1P-signalling.

  6. Data indicate that forkhead box F1 (Foxf1 (show FOXF1 Antibodies)) deletion from endothelial cells decreases the abundance of sphingosine 1-phosphate receptor 1 (S1PR1).

  7. Study provided evidence for a role of S1P1 in regulating oligodendrocyte differentiation and developmental myelination

  8. Galphas (show GNAS Antibodies) depletion blocks the S1PR1-activation induced VE-cadherin (show CDH5 Antibodies) stabilization at junctions.

  9. S1P is localized in the presynaptic regions of mature neurons and is regulated by sphingosine-1-phosphate.

  10. S1P1 receptor-selective up-regulation reduces the severity of acute graft versus host disease by inhibiting macrophage recruitment.

Cow (Bovine) Sphingosine-1-Phosphate Receptor 1 (S1PR1) interaction partners

  1. Polymorphisms in promoter regions of PDHB (show PDHB Antibodies), SORBS1 (show SORBS1 Antibodies), and EDG1 genes showing marbling-associated expression changes.

  2. we detected 2 novel SNPs, referred to as g.1475435G>A and g.1471620G>T, in the 5' flanking region of the EDG1 between low-marbled and high-marbled steer groups

  3. EDG1 SNPs, although they may not be regarded as a causal mutation, may be useful for effective marker-assisted selection to increase the levels of marbling in Japanese Black beef cattle.

S1PR1 Antigen Profile

Antigen Summary

The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion.

Alternative names and synonyms associated with S1PR1

  • sphingosine-1-phosphate receptor 5a (s1pr5a) antibody
  • sphingosine-1-phosphate receptor 1 (S1PR1) antibody
  • sphingosine-1-phosphate receptor 1 (S1pr1) antibody
  • AI849002 antibody
  • CD363 antibody
  • CHEDG1 antibody
  • D1S3362 antibody
  • ECGF1 antibody
  • EDG-1 antibody
  • Edg1 antibody
  • fd11a07 antibody
  • Lpb1 antibody
  • S1p antibody
  • S1p1 antibody
  • wu:fd11a07 antibody
  • zgc:92296 antibody

Protein level used designations for S1PR1

sphingosine-1-phosphate receptor 1 , sphingosine 1-phosphate receptor 1 , endothelial differentiation, sphingolipid G-protein-coupled receptor, 1 , S1P receptor 1 , S1P receptor Edg-1 , endothelial differentiation G-protein coupled receptor 1 , sphingosine 1-phosphate receptor EDG1 , sphingosine 1-phosphate receptor Edg-1 , endothelial differentiation sphingolipid G-protein-coupled receptor 1 , lysophospholipid receptor B1 , EDG1 (Edg1) , S1P1

492350 Danio rerio
100174622 Pongo abelii
424462 Gallus gallus
457063 Pan troglodytes
490138 Canis lupus familiaris
716813 Macaca mulatta
100050049 Equus caballus
1901 Homo sapiens
13609 Mus musculus
29733 Rattus norvegicus
281135 Bos taurus
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