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anti-Zebrafish (Danio rerio) Antibodies:
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Zebrafish (Danio rerio) Polyclonal SHHA Primary Antibody for WB - ABIN1882186
Ekker, Ungar, Greenstein, von Kessler, Porter, Moon, Beachy: Patterning activities of vertebrate hedgehog proteins in the developing eye and brain. in Current biology : CB 1995
Show all 4 Pubmed References
Mutation of hmgcs1 (show HMGCS1 Antibodies) had no effect on Shh (show SHH Antibodies) signaling at 2 and 3 days post fertilization (dpf), but did result in a decrease in the expression of gli1 (show GLI1 Antibodies), a known Shh (show SHH Antibodies) target gene, at 4 dpf, after morphological deficits in craniofacial development and chondrocyte differentiation were observed in hmgcs1 (show HMGCS1 Antibodies) mutants.
Shha/Smo is functionally dedicated to ray branching during fin regeneration.
Shh and Rx3 govern formation of a distinct progenitor domain that elaborates patterning through its anisotropic growth and differentiation.
Time-lapse imaging revealed that knockdown of miR (show MYLIP Antibodies)-219 function accelerates the growth of primary cilia, revealing a possible mechanistic link between miR (show MYLIP Antibodies)-219-mediated regulation of apical Par (show AFG3L2 Antibodies) proteins and Shh (show SHH Antibodies) signaling.
Shh (show SHH Antibodies) is not essential for the early activation of has2 (show HAS2 Antibodies), but supports proper chondrogenic differentiation.
Opposing Shh (show SHH Antibodies) and Fgf signals initiate nasotemporal patterning of the zebrafish retina.
Hedgehog (show SHH Antibodies) signaling has a role in dental papilla formation and tooth size during zebrafish odontogenesis
Data indicate that the transgenic lines report Hedgehog (show SHH Antibodies) pathway state in individual cells and with high sensitivity.
We further demonstrate that the elevated Hedgehog (show SHH Antibodies) signaling in Sox11 (show SOX11 Antibodies)-deficient zebrafish was caused by a large increase in shha transcription; indeed, suppressing Shha expression rescued the ocular phenotypes of sox11 (show SOX11 Antibodies) morphants.
Pax6 (show PAX6 Antibodies) has an evolutionarily conserved function in establishing the temporospatial expression of Shh (show SHH Antibodies) in the mid-diencephalic organizer in vertebrates.
Intercellular signal essential for a variety of patterning events during development. Signal produced by the notochord that induces somite patterning, dorso-ventral patterning of the brain and early patterning of the developing eyes. Displays floor plate-inducing activity. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO (By similarity).
sonic hedgehog protein A