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Rat (Rattus) Enkephalin ELISA Kit - ABIN457229
Nuseir, Alzoubi, Alabwaini, Khabour, Kassab: Sucrose-induced analgesia during early life modulates adulthood learning and memory formation. in Physiology & behavior 2015
The expression of the genes coding for proopiomelanocortin (POMC (show POMC ELISA Kits)), proenkephalin (PENK) and prodynorphin (PDYN (show PDYN ELISA Kits)) in porcine luteal cells isolated from corpora lutea (CL) collected on days 3-6, 8-10 and 13-16 of the oestrous cycle is reported.
Members of the SIN3A/HDAC2 corepressor complex are enriched in an extended NANOG interactome.
Functional studies revealed that knockdown of Nanog eliminated the mESC self-renewal-promoting ability of Sp5. Finally, we demonstrated that the self-renewal-promoting function of Sp5 was largely dependent on its zinc finger domains
Otx2 (show OTX2 ELISA Kits)-mediated Nanog (show NANOG ELISA Kits) regulation contributes to the integrity of the embryonic stem cell state and cell lineage specification in preimplantation development (show MTA2 ELISA Kits).
Maintenance of pluripotency is regulated by a network of transcription factors coordinated by Oct4 (show POU5F1 ELISA Kits), Sox2 (show SOX2 ELISA Kits), and Nanog (show NANOG ELISA Kits); Trim24 (show TRIM24 ELISA Kits) significantly improved efficiency of cellular reprogramming, demonstrating its direct functionality in establishing pluripotency.
studies highlight a new hypoxia-induced pathway in which NANOG (show NANOG ELISA Kits) activates BNIP3L (show BNIP3L ELISA Kits) expression, contributing to autophagy induction in hypoxic tumor cells and their resistance to killing by CTL
Genetic reporters can compromise the behavior of important pluripotency-sustaining positive feedback loops, and induce a bifurcation in the underlying dynamics that gives rise to heterogeneous Nanog expression patterns in reporter cell lines that are not representative of the wild-type; findings help explain the range of published observations of Nanog variability and highlight the problem of measurement in live cells.
Here the authors couple mutagenesis with functional and dimerization assays to show that the number of tryptophans within the tryptophan repeat is linked to the strength of homodimerization, Sox2 (show SOX2 ELISA Kits) heterodimerization and self-renewal activity.
In mouse model of acute uterine injury, Nanog (show NANOG ELISA Kits) homebox (NANOG (show NANOG ELISA Kits)) expression reached a peak at 6 h, while sex-determining region Y (show SRY ELISA Kits)-box2 (SOX2 (show SOX2 ELISA Kits)) and octamer-binding protein 4 (OCT4 (show POU5F1 ELISA Kits)) peaked later at 12 h after lipopolysaccharide (LPS (show TLR4 ELISA Kits)) treatment.
NANOG as a key regulator connecting the pluripotency network with constitutive heterochromatin organization in mouse embryonic stem cells.
Data indicate that Nanog homeobox (show NANOG ELISA Kits) protein (show HOXA1 ELISA Kits) is important for the effects of reprogramming media.
The concentration of PENK 143-183 was significantly greater in patients with Moyamoya disease (MMD) than control patients and decreased in an age-dependent manner in MMD.
Nav1.7 (show SCN9A ELISA Kits) deletion has profound effects on gene expression, leading to an upregulation of enkephalin precursor Penk mRNA and met-enkephalin protein in sensory neurons.
The PENK polymorphism-and potentially opioid neurotransmission more generally-modulates functioning and structural integrity of brain regions.
Serum PENK-A levels were not associated with all-cause mortality in patients with type 2 diabetes mellitus, and its association with cardiovascular mortality was strongly attenuated after accounting for all traditional risk factors.
BSP (show KLK6 ELISA Kits) demonstrated that emodin, to a certain degree, affected the demethylation of tumor-suppressor genes P16, RASSF1A (show RASSF1 ELISA Kits), and ppENK in the pancreatic cancer cell line PANC-1.
increased plasma PENK-A levels are associated with disease severity and in-hospital mortality after acute intracerebral hemorrhage.
enhanced plasma proenkephalin A could be a useful, complementary tool to predict short- or long-term clinical outcome after severe traumatic brain injury.
EPS led to the discovery of two novel immunomodulatory proteins, MFAP5 (show MFAP5 ELISA Kits) and PENK that when administered to mice subjected to endotoxemic shock, reversed the cytokine storm and provided a significant survival benefit
Data from women undergoing hysterectomy for uterine fibroids suggest that uterine isthmian-cervical region exhibits nerve fibers expressing enkephalin (ENK); uterine fundus/corpus myoma pseudocapsules do not exhibit nerve fibers expressing ENK.
Promoter methylation of WIF1 (show WIF1 ELISA Kits), PENK and NPY (show NPY ELISA Kits) is associated with colorectal adenocarcinoma (CRC (show CALR ELISA Kits)) diagnosis and can be used to CRC (show CALR ELISA Kits) from other cancers.
Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT-3'. When overexpressed, promotes cells to enter into S phase and proliferation (By similarity).
, ES cell-associated protein 4
, early embryo specific expression NK family
, early embryo specific expression NK-type homeobox protein
, homeobox protein NANOG
, homeobox transcription factor Nanog
, enkephalin A
, preproenkephalin 1
, spermatogenic-specific proenkephalin
, Proenkephalin A
, preproenkephalin 2
, proenkephalin 1
, proenkephalin 2
, proenkephalin related sequence
, enkephalin a