Browse our CYP1B1 Proteins (CYP1B1)

Full name:
Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 Proteins (CYP1B1)
On www.antibodies-online.com are 5 Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1) Proteins from 4 different suppliers available. Additionally we are shipping CYP1B1 Antibodies (124) and CYP1B1 Kits (23) and many more products for this protein. A total of 158 CYP1B1 products are currently listed.
Synonyms:
CP1B, CYP1B, CYP1B1, CYPIB1, GLC3A, P4501b1, zgc:136223
list all proteins Gene Name GeneID UniProt
CYP1B1 1545 Q16678
CYP1B1 13078 Q64429
Rat CYP1B1 CYP1B1 25426 Q64678

Show all synonyms

CYP1B1 Proteins (CYP1B1) by Origin

Select your origin of interest

More Proteins for CYP1B1 Interaction Partners

Human Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1) interaction partners

  1. CYP1B1 genotype activity and the microscopic and clinical phenotypes in human primary congenital glaucoma

  2. Utilizing a mouse model, null for Cyp1b1 and expressing human CYP1B1, the study tested the hypothesis that hCYP1B1 is important for dibenzo[def,p]chrysene (DBC) transplacental carcinogenesis. hCYP1B1 genotype did not impact lung tumor multiplicity, but tended to enhance incidence compared to Cyp1b1 wild-type mice (P = 0.07).

  3. CYP1B1 haplotypes could be more effective in predicting Head and Neck Squamous Cell Carcinoma risk.

  4. Our data suggest that interaction of TEK (show TEK Proteins) and CYP1B1 contributes to primary congenital glaucoma pathogenesis and argue that TEK (show TEK Proteins)-CYP1B1 may perform overlapping as well as distinct functions in manifesting the disease etiology.

  5. molecular basis of the variable phenotypes resulting from the defects in CYP1B1 by using subclones of 23 CYP1B1 mutants reported in glaucoma patients

  6. Cyp1b1 regulation of ocular fissure closure indirectly affects neural crest migration and development through an RA-independent pathway.

  7. MicroRNA-187-5p suppresses cancer cell progression in non-small cell lung cancer through down-regulation of CYP1B1.

  8. CYP1B1, which is also regulated by the AHR (show AHR Proteins), plays a mechanistic role in oxygen toxicity in pulmonary cells.

  9. We identified four homozygous missense mutations (c.1405C>T, p.R469W; c.1397G>T, p.G466V; c.1198C>T, p.P400S; and c.1103G>A, p.R368H) in CYP1B1 in eight Indian families. Among the five mutations identified, G466V in CYP1B1 represent novel mutations.

  10. Five out of 30 families with PCG (16.7%) had disease attributable to CYP1B1 alterations suggesting that CYP1B1 is not the major gene causing PCG in Vietnamese unlike in the case of Arab or Romany patients.

Mouse (Murine) Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1) interaction partners

  1. Utilizing a mouse model, null for Cyp1b1 and expressing human CYP1B1, the study tested the hypothesis that hCYP1B1 is important for dibenzo[def,p]chrysene (DBC) transplacental carcinogenesis. hCYP1B1 genotype did not impact lung tumor multiplicity, but tended to enhance incidence compared to Cyp1b1 wild-type mice (P = 0.07).

  2. CYP1B1 contributed to the development of Ang II (show AGT Proteins)-induced abdominal aortic aneurysm and associated pathogenic events in mice, likely by enhancing oxidative stress and associated signaling events

  3. Miroestrol suppressed beta-naphthoflavone increases in CYP1B1.

  4. Findings provide evidence that CYP1B1 is directly involved in the development of cardiac hypertrophy.

  5. Cyp1b1 affects external control of mouse hepatocytes, fatty acid homeostasis and signaling involving HNF4alpha (show HNF4A Proteins) and PPARalpha (show PPARA Proteins).

  6. hypertension, and associated pathogenesis in ApoE (show APOE Proteins)(-/-)/Cyp1b1(+/+) mice on an atherogenic diet are most likely dependent on CYP1B1-generated oxidative stress and increased plasma lipid levels independent of blood pressure and absorption of lipids.

  7. Follicle stimulating hormone functions via p38 MAPK (show MAPK14 Proteins)-induced dephosphorylation at Ser (show SIGLEC1 Proteins)(727) of STAT1 (show STAT1 Proteins) to downregulate Cyp1b1 expression and maintain the estradiol levels in mouse dominant follicles.

  8. Cyp1b1 contributes to angiotensin II induced hypertension and its pathogenesis in male mice.

  9. Suggest that Cyp1b1 plays a critical role in female mice in protecting against renal dysfunction and end-organ damage associated with ANG II (show AGT Proteins)-induced hypertension.

  10. Data indicaate that adduct formation in cytochrome P450 Cyp1b1 knockout mice was significantly reduced compared to wild-type mice receiving dibenzo[def,p]chrysene (DBC).

Zebrafish Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1) interaction partners

  1. CYP1B1 knockdown studies show CYP1B1 is not a significant factor in causing synergistic toxicity of PAHs, nor, in contrast to CYP1A, in providing protection

CYP1B1 Protein Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma\; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.

Alternative names and synonyms associated with CYP1B1

  • cytochrome P450 1B1 (CYP1B1)
  • cytochrome P450, family 1, subfamily B, polypeptide 1 (CYP1B1)
  • cytochrome P450 1B1-like (LOC100719054)
  • cytochrome P450, family 1, subfamily b, polypeptide 1 (Cyp1b1)
  • cytochrome P450, family 1, subfamily B, polypeptide 1 (cyp1b1)
  • CP1B protein
  • CYP1B protein
  • CYP1B1 protein
  • CYPIB1 protein
  • GLC3A protein
  • P4501b1 protein
  • zgc:136223 protein

Protein level used designations for CYP1B1

cytochrome P450 1B1 , cytochrome P450, family 1, subfamily B, polypeptide 1 , aryl hydrocarbon hydroxylase , cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile) , flavoprotein-linked monooxygenase , microsomal monooxygenase , xenobiotic monooxygenase , CYPIB1 , benz[a]anthracene inducible , cytochrome P450, 1b1, benz[a]anthracene inducible , cytochrome P450CMEF , cytochrome P450EF , P450RAP , cytochrome P450, subfamily 1B, polypeptide 1 , cytochrome P450RAP , cytochrome P4501B

GENE ID SPECIES
100079784 Ornithorhynchus anatinus
100172192 Pongo abelii
459163 Pan troglodytes
100719054 Cavia porcellus
1545 Homo sapiens
428832 Gallus gallus
511470 Bos taurus
13078 Mus musculus
25426 Rattus norvegicus
100150054 Danio rerio
483038 Canis lupus familiaris
421466 Gallus gallus
Selected quality suppliers for CYP1B1 Proteins (CYP1B1)
Did you look for something else?