Browse our anti-CYP3A4 (CYP3A4) Antibodies

Full name:
anti-Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 Antibodies (CYP3A4)
On www.antibodies-online.com are 116 Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4) Antibodies from 22 different suppliers available. Additionally we are shipping CYP3A4 Kits (34) and CYP3A4 Proteins (6) and many more products for this protein. A total of 165 CYP3A4 products are currently listed.
Synonyms:
CP33, CP34, CYP3A, CYP3A3, CYP3A4, CYP3A12, CYP3A21, CYP3A80, CYPIIIA3, CYPIIIA4, CYPIIIA21, HLP, MGC108372, NF-25, P450C3, P450PCN1
list all antibodies Gene Name GeneID UniProt
CYP3A4 1576 P08684
CYP3A4    
CYP3A4    

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Most Popular Reactivities for anti-CYP3A4 (CYP3A4) Antibodies

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anti-Human CYP3A4 Antibodies:

anti-Rat (Rattus) CYP3A4 Antibodies:

anti-Mouse (Murine) CYP3A4 Antibodies:

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Top referenced anti-CYP3A4 Antibodies

  1. Human Polyclonal CYP3A4 Primary Antibody for EIA, WB - ABIN360097 : Nelson, Zeldin, Hoffman, Maltais, Wain, Nebert: Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. in Pharmacogenetics 2004 (PubMed)
    Show all 3 references for 360097

  2. Human Monoclonal CYP3A4 Primary Antibody for ICC, FACS - ABIN969512 : van Waterschoot, Rooswinkel, Sparidans, van Herwaarden, Beijnen, Schinkel: Inhibition and stimulation of intestinal and hepatic CYP3A activity: studies in humanized CYP3A4 transgenic mice using triazolam. in Drug metabolism and disposition: the biological fate of chemicals 2009 (PubMed)
    Show all 2 references for 969512

  3. Human Polyclonal CYP3A4 Primary Antibody for IHC, ELISA - ABIN1450923 : Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... in Nature 2003 (PubMed)
    Show all 2 references for 1450923

  4. Cow (Bovine) Polyclonal CYP3A4 Primary Antibody for WB - ABIN2784528 : Werk, Lefeldt, Bruckmueller, Hemmrich-Stanisak, Franke, Roos, Küchle, Steubl, Schmaderer, Bräsen, Heemann, Cascorbi, Renders: Identification and characterization of a defective CYP3A4 genotype in a kidney transplant patient with severely diminished tacrolimus clearance. in Clinical pharmacology and therapeutics 2014 (PubMed)

  5. Human Polyclonal CYP3A4 Primary Antibody for IP, WB - ABIN947776 : Fujiwara, Itoh: Extensive protein interactions involving cytochrome P450 3A4: a possible contributor to the formation of a metabolosome. in Pharmacology research & perspectives 2014 (PubMed)

More Antibodies against CYP3A4 Interaction Partners

Horse (Equine) Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4) interaction partners

  1. It was concluded that CYP3A related metabolism in horse is not solely dependent on the expression of the enzyme but also on adequate levels of NADPH P450 reductase (show POR Antibodies) and cytochrome b(5 (show CYB5A Antibodies)).

Human Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4) interaction partners

  1. Cross-talk between pregnane X receptor (show NR1I2 Antibodies) and AhR (show AHR Antibodies) plays a role in rifampicin regulation of CYP3A4 gene expression.

  2. We observed an association between ABCB1 (show ABCB1 Antibodies) 3435 T/T and lower grade of toxicities (p=0.05) in patients receiving taxanes for breast cancer. No other associations were found for CYP (show PPIG Antibodies) 3A4 *1B, 3A5*3 and ABCB1 (show ABCB1 Antibodies) C1236T.

  3. The authors found a correlation between genetic SNP variations in CYP3A4 enzyme and tacrolimus blood levels in this Jordanian kidney transplant recipients.

  4. Hypertension is more likely to occur in A-allele carriers of the CYP3A4 rs4646437 variant in a cohort of metastatic renal carcinoma (show TSC2 Antibodies) patients treated with sunitinib.

  5. P450 (show CYP2B6 Antibodies) 3A4 is the major liver enzyme responsible for the metabolic activation of berbamine.

  6. CYP3A4*1G and CYP3A5 (show CYP3A5 Antibodies)*3 genetic polymorphisms alter the antihypertensive efficacy of amlodipine in patients with hypertension following renal transplantation.

  7. The CYP3A4 polymorphism A/A+A/G influenced the difference in the mean lymphocyte MN frequency (MNF (show Foxk1 Antibodies)) & micronucleated cell frequency (MNC). After adjusting risk factors, the MNF (show Foxk1 Antibodies) level in the MBOCA-exposed workers was 0.520 MN cells/1000 cells higher than the control group among the CYP3A4 A/A+A/G genotype. Similarly, the MNC level in the MBOCA-exposed workers was 0.593 MN/1000 cells higher than the control group.

  8. miR (show MLXIP Antibodies)-30c-1-3p was shown to alter the expression of CYP3A4, a prototypical target gene of PXR (show NR1I2 Antibodies).

  9. Results show that breast cancer cells resistant to neratinib present an increase expression of CYP3A4 suggesting that increased CYP3A4 activity as a novel mechanism of neratinib resistance.

  10. Results indicate that cytochrome P450 3A4 (CYP3A4) is highly sensitive to the acyl-chain composition of the lipids and fluidity of the membrane in which it is embedded.

CYP3A4 Antigen Profile

Antigen Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist\; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with CYP3A4

  • cytochrome P450 3A4 (PTRG_01782) antibody
  • cytochrome P450 3A4 (PTRG_06060) antibody
  • cytochrome P450, family 3, subfamily A, polypeptide 4 (cyp3a4) antibody
  • cytochrome P450, family 3, subfamily A, polypeptide 4 (CYP3A4) antibody
  • cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 (CYP3A4) antibody
  • cytochrome P450, subfamily IIIA, polypeptide 4 (CYP3A4) antibody
  • CP33 antibody
  • CP34 antibody
  • CYP3A antibody
  • CYP3A3 antibody
  • CYP3A4 antibody
  • CYP3A12 antibody
  • CYP3A21 antibody
  • CYP3A80 antibody
  • CYPIIIA3 antibody
  • CYPIIIA4 antibody
  • CYPIIIA21 antibody
  • HLP antibody
  • MGC108372 antibody
  • NF-25 antibody
  • P450C3 antibody
  • P450PCN1 antibody

Protein level used designations for CYP3A4

cytochrome P450 3A4 , cytochrome P450, family 3, subfamily A, polypeptide 4 , cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 , Cytochrome P450 CM3A-10 , cytochrome P450 3A21 , 1,8-cineole 2-exo-monooxygenase , P450-III, steroid inducible , albendazole monooxygenase , albendazole sulfoxidase , cytochrome P450 3A3 , cytochrome P450 HLp , cytochrome P450 NF-25 , cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3 , cytochrome P450-PCN1 , glucocorticoid-inducible P450 , nifedipine oxidase , quinine 3-monooxygenase , taurochenodeoxycholate 6-alpha-hydroxylase , cytochrome P450 CYP3A12 , cytochrome P450 3A80

GENE ID SPECIES
6339762 Pyrenophora tritici-repentis Pt-1C-BFP
6344316 Pyrenophora tritici-repentis Pt-1C-BFP
548503 Xenopus (Silurana) tropicalis
463582 Pan troglodytes
100037189 Xenopus laevis
100294525 Equus caballus
100404344 Callithrix jacchus
100462903 Macaca mulatta
1576 Homo sapiens
479740 Canis lupus familiaris
416477 Gallus gallus
507988 Bos taurus
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