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Browse our anti-CYP3A4 (CYP3A4) Antibodies

Full name:
anti-Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 Antibodies (CYP3A4)
On are 115 Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4) Antibodies from 22 different suppliers available. Additionally we are shipping CYP3A4 Kits (34) and CYP3A4 Proteins (6) and many more products for this protein. A total of 164 CYP3A4 products are currently listed.
CP33, CP34, CYP3A, CYP3A3, CYP3A4, CYP3A12, CYP3A21, CYP3A80, CYPIIIA3, CYPIIIA4, CYPIIIA21, HLP, MGC108372, NF-25, P450C3, P450PCN1
list all antibodies Gene Name GeneID UniProt
CYP3A4 1576 P08684

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Most Popular Reactivities for anti-CYP3A4 (CYP3A4) Antibodies

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anti-Human CYP3A4 Antibodies:

anti-Rat (Rattus) CYP3A4 Antibodies:

anti-Mouse (Murine) CYP3A4 Antibodies:

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Top referenced anti-CYP3A4 Antibodies

  1. Human Polyclonal CYP3A4 Primary Antibody for EIA, WB - ABIN360097 : Nelson, Zeldin, Hoffman, Maltais, Wain, Nebert: Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. in Pharmacogenetics 2004 (PubMed)
    Show all 3 references for ABIN360097

  2. Human Polyclonal CYP3A4 Primary Antibody for IHC, ELISA - ABIN1450923 : Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... in Nature 2003 (PubMed)
    Show all 2 references for ABIN1450923

  3. Human Monoclonal CYP3A4 Primary Antibody for ICC, FACS - ABIN969512 : van Waterschoot, Rooswinkel, Sparidans, van Herwaarden, Beijnen, Schinkel: Inhibition and stimulation of intestinal and hepatic CYP3A activity: studies in humanized CYP3A4 transgenic mice using triazolam. in Drug metabolism and disposition: the biological fate of chemicals 2009 (PubMed)
    Show all 2 references for ABIN969512

  4. Cow (Bovine) Polyclonal CYP3A4 Primary Antibody for WB - ABIN2784528 : Werk, Lefeldt, Bruckmueller, Hemmrich-Stanisak, Franke, Roos, Küchle, Steubl, Schmaderer, Bräsen, Heemann, Cascorbi, Renders: Identification and characterization of a defective CYP3A4 genotype in a kidney transplant patient with severely diminished tacrolimus clearance. in Clinical pharmacology and therapeutics 2014 (PubMed)

  5. Human Polyclonal CYP3A4 Primary Antibody for IP, WB - ABIN947776 : Fujiwara, Itoh: Extensive protein interactions involving cytochrome P450 3A4: a possible contributor to the formation of a metabolosome. in Pharmacology research & perspectives 2014 (PubMed)

More Antibodies against CYP3A4 Interaction Partners

Horse (Equine) Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4) interaction partners

  1. It was concluded that CYP3A related metabolism in horse is not solely dependent on the expression of the enzyme but also on adequate levels of NADPH P450 reductase (show POR Antibodies) and cytochrome b(5 (show CYB5A Antibodies)).

Human Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4) interaction partners

  1. miR (show MLXIP Antibodies)-30c-1-3p was shown to alter the expression of CYP3A4, a prototypical target gene of PXR (show NR1I2 Antibodies).

  2. Results show that breast cancer cells resistant to neratinib present an increase expression of CYP3A4 suggesting that increased CYP3A4 activity as a novel mechanism of neratinib resistance.

  3. Results indicate that cytochrome P450 3A4 (CYP3A4) is highly sensitive to the acyl-chain composition of the lipids and fluidity of the membrane in which it is embedded.

  4. The result provides the first direct evidence for an allosteric effect of the peripheral binding site at the protein-membrane interface on the functional properties of CYP3A4.

  5. FGF21 (show FGF21 Antibodies)-PXR (show NR1I2 Antibodies) signaling pathway may be involved in decreased hepatic CYP3A4 metabolic activity in Nonalcoholic fatty liver disease.

  6. This work applies a new strategy to study cytochrome P450 (show CYP Antibodies) allostery and supports the hypothesis that substrate binding at the postulated allosteric site of CYP3A4 may induce functional cooperativity.

  7. The possible association of CYP3A5*3 and CYP3A4*1G polymorphisms on CYP3A activity.

  8. activity assays with the human CYP3A4-specific Luciferin isopropyl acetal (Luciferin-IPA) as well as inhibition studies with ketoconazole and CYP3cide were carried out to identify CYP (show PPIG Antibodies) activity in zebrafish liver microsomes.

  9. Both pazopanib and ketoconazole were docked into the activity cavity of CYP3A4.

  10. data suggested that hepatocyte nuclear factor 4 alpha and glucocorticoid receptor, and epigenetic changes of H3K4me2 and H3K27me3 are associated with the ontogenic expressions of CYP3A4/3A7 in the livers of the Chinese Han population.

CYP3A4 Antigen Profile

Antigen Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist\; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with CYP3A4

  • cytochrome P450 3A4 (PTRG_01782) antibody
  • cytochrome P450 3A4 (PTRG_06060) antibody
  • cytochrome P450, family 3, subfamily A, polypeptide 4 (cyp3a4) antibody
  • cytochrome P450, family 3, subfamily A, polypeptide 4 (CYP3A4) antibody
  • cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 (CYP3A4) antibody
  • cytochrome P450, subfamily IIIA, polypeptide 4 (CYP3A4) antibody
  • CP33 antibody
  • CP34 antibody
  • CYP3A antibody
  • CYP3A3 antibody
  • CYP3A4 antibody
  • CYP3A12 antibody
  • CYP3A21 antibody
  • CYP3A80 antibody
  • CYPIIIA3 antibody
  • CYPIIIA4 antibody
  • CYPIIIA21 antibody
  • HLP antibody
  • MGC108372 antibody
  • NF-25 antibody
  • P450C3 antibody
  • P450PCN1 antibody

Protein level used designations for CYP3A4

cytochrome P450 3A4 , cytochrome P450, family 3, subfamily A, polypeptide 4 , cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 , Cytochrome P450 CM3A-10 , cytochrome P450 3A21 , 1,8-cineole 2-exo-monooxygenase , P450-III, steroid inducible , albendazole monooxygenase , albendazole sulfoxidase , cytochrome P450 3A3 , cytochrome P450 HLp , cytochrome P450 NF-25 , cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3 , cytochrome P450-PCN1 , glucocorticoid-inducible P450 , nifedipine oxidase , quinine 3-monooxygenase , taurochenodeoxycholate 6-alpha-hydroxylase , cytochrome P450 CYP3A12 , cytochrome P450 3A80

6339762 Pyrenophora tritici-repentis Pt-1C-BFP
6344316 Pyrenophora tritici-repentis Pt-1C-BFP
548503 Xenopus (Silurana) tropicalis
463582 Pan troglodytes
100037189 Xenopus laevis
100294525 Equus caballus
100404344 Callithrix jacchus
100462903 Macaca mulatta
1576 Homo sapiens
479740 Canis lupus familiaris
416477 Gallus gallus
507988 Bos taurus
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