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Browse our anti-CYP3A4 (CYP3A4) Antibodies

Full name:
anti-Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 Antibodies (CYP3A4)
On www.antibodies-online.com are 119 Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4) Antibodies from 21 different suppliers available. Additionally we are shipping CYP3A4 Kits (29) and CYP3A4 Proteins (6) and many more products for this protein. A total of 162 CYP3A4 products are currently listed.
Synonyms:
CP33, CP34, CYP3A, CYP3A3, CYP3A4, CYP3A12, CYP3A21, CYP3A80, CYPIIIA3, CYPIIIA4, CYPIIIA21, HLP, MGC108372, NF-25, P450C3, P450PCN1
list all antibodies Gene Name GeneID UniProt
CYP3A4 1576 P08684
CYP3A4    
CYP3A4    

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Most Popular Reactivities for anti-CYP3A4 (CYP3A4) Antibodies

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anti-Human CYP3A4 Antibodies:

anti-Rat (Rattus) CYP3A4 Antibodies:

anti-Mouse (Murine) CYP3A4 Antibodies:

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Top referenced anti-CYP3A4 Antibodies

  1. Human Polyclonal CYP3A4 Primary Antibody for EIA, WB - ABIN360097 : Nelson, Zeldin, Hoffman, Maltais, Wain, Nebert: Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. in Pharmacogenetics 2004 (PubMed)
    Show all 3 references for ABIN360097

  2. Human Monoclonal CYP3A4 Primary Antibody for ICC, FACS - ABIN969512 : van Waterschoot, Rooswinkel, Sparidans, van Herwaarden, Beijnen, Schinkel: Inhibition and stimulation of intestinal and hepatic CYP3A activity: studies in humanized CYP3A4 transgenic mice using triazolam. in Drug metabolism and disposition: the biological fate of chemicals 2009 (PubMed)
    Show all 2 references for ABIN969512

  3. Human Polyclonal CYP3A4 Primary Antibody for IHC, ELISA - ABIN1450923 : Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... in Nature 2003 (PubMed)
    Show all 2 references for ABIN1450923

  4. Human Polyclonal CYP3A4 Primary Antibody for IP, WB - ABIN947776 : Fujiwara, Itoh: Extensive protein interactions involving cytochrome P450 3A4: a possible contributor to the formation of a metabolosome. in Pharmacology research & perspectives 2014 (PubMed)

  5. Human Polyclonal CYP3A4 Primary Antibody for WB - ABIN2784528 : Werk, Lefeldt, Bruckmueller, Hemmrich-Stanisak, Franke, Roos, Küchle, Steubl, Schmaderer, Bräsen, Heemann, Cascorbi, Renders: Identification and characterization of a defective CYP3A4 genotype in a kidney transplant patient with severely diminished tacrolimus clearance. in Clinical pharmacology and therapeutics 2014 (PubMed)

More Antibodies against CYP3A4 Interaction Partners

Horse (Equine) Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4) interaction partners

  1. It was concluded that CYP3A related metabolism in horse is not solely dependent on the expression of the enzyme but also on adequate levels of NADPH P450 reductase (show POR Antibodies) and cytochrome b(5 (show CYB5A Antibodies)).

Human Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4) interaction partners

  1. Both pazopanib and ketoconazole were docked into the activity cavity of CYP3A4.

  2. data suggested that hepatocyte nuclear factor 4 alpha and glucocorticoid receptor, and epigenetic changes of H3K4me2 and H3K27me3 are associated with the ontogenic expressions of CYP3A4/3A7 in the livers of the Chinese Han population.

  3. The results of this study showed that no significant association between CYP3A5 (show CYP3A5 Antibodies)*3 polymorphism and drug-resistance was found.

  4. While CYP2C19 (show CYP2C19 Antibodies) genetic polymorphisms significantly affected plasma pantoprazole concentrations, polymorphisms of CYP2C19 (show CYP2C19 Antibodies), CYP3A4 and MDR1 (show TBC1D9 Antibodies) did not affect H. pylori eradication rates.

  5. Tamsulosin and tolterodine interfere with CYP3A4 gene expression and activity in an enantiomer-specific way.

  6. amount of sufentanil consumed in general anesthesia of patients with CYP3A4*1G point mutation significantly lower than that in the wild type group

  7. findings suggested that polymorphisms of CYP3A4 gene may be associated with susceptibility to steroid-induced osteonecrosis of the femoral head

  8. These results suggested that CYP3A4 flexibility has a significant influence on the permeation ability of 1,3,7-Trimethyluric Acid.

  9. These results suggest the existence of a marked inter-individual variability regarding the presence of the isoforms of CYP3A. In addition, since sorafenib is metabolized by CYP3A4, but not by CYP3A7 (show CYP3A7 Antibodies), an overexpression of CYP3A4 may lead to an increase in the degradation of the drug and then to clinical ineffectiveness.

  10. findings suggest that steroid hormones are able to regulate CYP3A4 mRNA expression, although the circulating levels of these hormones can only regulate control endometrium and not endometriosis tissues, probably because of dysregulated local steroid concentration in these latter samples.

CYP3A4 Antigen Profile

Antigen Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist\; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with CYP3A4

  • cytochrome P450 3A4 (PTRG_01782) antibody
  • cytochrome P450 3A4 (PTRG_06060) antibody
  • cytochrome P450, family 3, subfamily A, polypeptide 4 (cyp3a4) antibody
  • cytochrome P450, family 3, subfamily A, polypeptide 4 (CYP3A4) antibody
  • cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 (CYP3A4) antibody
  • cytochrome P450, subfamily IIIA, polypeptide 4 (CYP3A4) antibody
  • CP33 antibody
  • CP34 antibody
  • CYP3A antibody
  • CYP3A3 antibody
  • CYP3A4 antibody
  • CYP3A12 antibody
  • CYP3A21 antibody
  • CYP3A80 antibody
  • CYPIIIA3 antibody
  • CYPIIIA4 antibody
  • CYPIIIA21 antibody
  • HLP antibody
  • MGC108372 antibody
  • NF-25 antibody
  • P450C3 antibody
  • P450PCN1 antibody

Protein level used designations for CYP3A4

cytochrome P450 3A4 , cytochrome P450, family 3, subfamily A, polypeptide 4 , cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 , Cytochrome P450 CM3A-10 , cytochrome P450 3A21 , 1,8-cineole 2-exo-monooxygenase , P450-III, steroid inducible , albendazole monooxygenase , albendazole sulfoxidase , cytochrome P450 3A3 , cytochrome P450 HLp , cytochrome P450 NF-25 , cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3 , cytochrome P450-PCN1 , glucocorticoid-inducible P450 , nifedipine oxidase , quinine 3-monooxygenase , taurochenodeoxycholate 6-alpha-hydroxylase , cytochrome P450 CYP3A12 , cytochrome P450 3A80

GENE ID SPECIES
6339762 Pyrenophora tritici-repentis Pt-1C-BFP
6344316 Pyrenophora tritici-repentis Pt-1C-BFP
548503 Xenopus (Silurana) tropicalis
463582 Pan troglodytes
100037189 Xenopus laevis
100294525 Equus caballus
100404344 Callithrix jacchus
100462903 Macaca mulatta
1576 Homo sapiens
479740 Canis lupus familiaris
416477 Gallus gallus
507988 Bos taurus
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