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Browse our CYP3A7 Proteins (CYP3A7)

Full name:
Cytochrome P450, Family 3, Subfamily A, Polypeptide 7 Proteins (CYP3A7)
On are 5 Cytochrome P450, Family 3, Subfamily A, Polypeptide 7 (CYP3A7) Proteins from 4 different suppliers available. Additionally we are shipping CYP3A7 Antibodies (51) and CYP3A7 Kits (3) and many more products for this protein. A total of 64 CYP3A7 products are currently listed.
list all proteins Gene Name GeneID UniProt
CYP3A7 1551 P24462

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Human Cytochrome P450, Family 3, Subfamily A, Polypeptide 7 (CYP3A7) interaction partners

  1. The CYP3A7*1C allele is associated with a lower urinary estrone levels, a more pronounced reduction in 2-hydroxylation pathway estrone metabolites (EMs) and a lower ratio of 2-hydroxylation:16alpha-hydroxylation EMs in premenopausal women.

  2. data suggested that hepatocyte nuclear factor 4 alpha and glucocorticoid receptor, and epigenetic changes of H3K4me2 and H3K27me3 are associated with the ontogenic expressions of CYP3A4/3A7 in the livers of the Chinese Han population.

  3. These results suggest the existence of a marked inter-individual variability regarding the presence of the isoforms of CYP3A (show CYP3A4 Proteins). In addition, since sorafenib is metabolized by CYP3A4 (show CYP3A4 Proteins), but not by CYP3A7, an overexpression of CYP3A4 (show CYP3A4 Proteins) may lead to an increase in the degradation of the drug and then to clinical ineffectiveness.

  4. CYP3A7*1C influences outcome are required.

  5. CYP3A4 (show CYP3A4 Proteins), CYP3A7, UGT2B11 and UGT2B15 (show UGT2B15 Proteins) genes are significantly downregulated in melanosis coli.

  6. Differences in the expression of nuclear receptors might determine the variability in CYP3A4 (show CYP3A4 Proteins) and CYP3A7 expression observed in foetal liver.

  7. Only CYP1A1 (show CYP1A1 Proteins), CYP1B1 (show CYP1B1 Proteins), CYP3A4 (show CYP3A4 Proteins), CYP3A5 (show CYP3A5 Proteins) and CYP3A7 expressed in lymphocytes and monocytes.

  8. Report CYP3A7 metabolism of inhaled glucocorticoids.

  9. Report distinctive response patterns of HIF-1alpha (show HIF1A Proteins), CYP3A4 (show CYP3A4 Proteins) and CYP3A7 to cobalt chloride in human fetal liver cells.

  10. Expression and regulation of human fetal-specific CYP3A7 in mice

CYP3A7 Protein Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. The enzyme also metabolizes some drugs such as aflatoxin B1. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Transcript variants have been described, but it is not known whether these transcripts are normally produced. This gene undergoes readthrough transcription with the downstream CYP3AP1 pseudogene, resulting in an isoform with a novel C-terminus, as represented in GeneID:100861540.

Alternative names and synonyms associated with CYP3A7

  • cytochrome P450, family 3, subfamily A, polypeptide 7 (CYP3A7)
  • CP37 protein
  • CYPIIIA7 protein
  • P450-HFLA protein

Protein level used designations for CYP3A7

cytochrome P450 3A7 , aryl hydrocarbon hydroxylase , cytochrome P450, subfamily IIIA, polypeptide 7 , cytochrome P450-HFLA , flavoprotein-linked monooxygenase , microsomal monooxygenase , xenobiotic monooxygenase

100144394 Macaca mulatta
1551 Homo sapiens
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